[Hub]/) : Traits : Medication: Cholesterol lowering : ← →

chr5:73,969,058-75,594,743

Best TWAS P=3.27e-14 · Best GWAS P=1.55e-13 conditioned to 0.163

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	HMGCR	0.04	0.02	enet	4	0.03	6.0e-03	7.4	7.6	3.3e-14	0.89	0.00	0.91	TRUE
2	GTEx	Esophagus Mucosa	COL4A3BP	0.09	0.06	lasso	5	0.05	4.2e-04	6.4	-6.6	5.6e-11	-0.69	0.11	0.87	FALSE
5	The Cancer Genome Atlas	Prostate Adenocarcinoma	POLK	0.03	0.01	blup	53	0.01	1.6e-02	5.0	-5.9	4.7e-09	-0.63	0.07	0.87	FALSE
1	GTEx	Brain Cerebellar Hemisphere	POLK	0.27	0.20	lasso	6	0.16	8.3e-05	5.9	5.4	8.5e-08	0.64	0.31	0.24	FALSE
3	GTEx	Thyroid	CTC-366B18.2	0.06	0.03	lasso	9	0.02	6.2e-03	5.3	5.3	1.3e-07	0.57	0.29	0.19	FALSE