Best TWAS P=6.41e-09 · Best GWAS P=3.43e-12 conditioned to 1.02e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATP5G1 | 0.07 | 0.05 | lasso | 3 | 0.06 | 4.7e-08 | -4.8 | 5.1 | 2.8e-07 | -0.01 | 0.99 | 0.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | RP11-463M16.4 | 0.10 | 0.00 | enet | 21 | 0.01 | 2.8e-02 | -5.0 | 5.5 | 3.9e-08 | 0.22 | 0.27 | 0.07 | FALSE |
| 3 | GTEx | Esophagus Muscularis | SNF8 | 0.08 | 0.03 | lasso | 3 | 0.01 | 5.7e-02 | -5.0 | 5.2 | 1.9e-07 | -0.06 | 0.12 | 0.04 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 2.6e-04 | 5.0 | -5.3 | 1.0e-07 | -0.80 | 0.11 | 0.75 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 2.5e-03 | 6.2 | -5.8 | 6.4e-09 | -0.79 | 0.04 | 0.87 | TRUE |