Best TWAS P=2.95e-09 · Best GWAS P=1.42e-07 conditioned to 1.11e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | TSPY26P | 0.08 | 0.01 | lasso | 4 | 0.03 | 1.7e-03 | -4.6 | -5.9 | 4.0e-09 | 0.16 | 0.08 | 0.70 | FALSE |
| 2 | GTEx | Brain Cerebellum | TSPY26P | 0.25 | 0.06 | lasso | 6 | 0.15 | 2.9e-05 | 4.2 | -5.9 | 2.9e-09 | 0.16 | 0.06 | 0.43 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | TSPY26P | 0.07 | 0.05 | lasso | 5 | 0.03 | 1.2e-03 | 4.8 | -5.3 | 1.2e-07 | 0.11 | 0.04 | 0.81 | FALSE |
| 4 | GTEx | Thyroid | TSPY26P | 0.12 | 0.08 | enet | 18 | 0.08 | 7.2e-07 | -4.6 | -5.6 | 1.8e-08 | 0.25 | 0.09 | 0.89 | FALSE |