Best TWAS P=6.39e-10 · Best GWAS P=2.99e-19 conditioned to 2.19e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | PLCB1 | 0.06 | 0.01 | lasso | 3 | 0.03 | 7.8e-05 | 0.35 | 6.2 | 6.4e-10 | -0.69 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | PLCB1 | 0.23 | 0.09 | lasso | 9 | 0.09 | 1.7e-06 | -7.29 | 6.0 | 1.7e-09 | -0.55 | 0.66 | 0.21 | TRUE |