Best TWAS P=1.34e-08 · Best GWAS P=9.4e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | NME6 | 0.12 | 0.07 | lasso | 9 | 0.08 | 6.1e-04 | -5.3 | 5.4 | 5.9e-08 | -0.97 | 0.04 | 0.88 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | FCF1P2 | 0.07 | 0.04 | lasso | 7 | 0.02 | 5.1e-02 | -5.3 | 5.3 | 1.2e-07 | -1.00 | 0.02 | 0.95 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | FCF1P2 | 0.09 | 0.01 | lasso | 4 | 0.03 | 8.6e-02 | -4.3 | 5.5 | 3.8e-08 | -0.88 | 0.03 | 0.66 | FALSE |
| 4 | GTEx | Pituitary | SLC26A6 | 0.16 | 0.18 | lasso | 8 | 0.14 | 2.0e-04 | -5.2 | -5.1 | 2.7e-07 | 0.98 | 0.02 | 0.84 | FALSE |
| 5 | NTR | Blood | ZNF589 | 0.02 | 0.02 | lasso | 8 | 0.02 | 2.8e-06 | -5.3 | -5.7 | 1.3e-08 | 0.97 | 0.01 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CDC25A | 0.02 | 0.00 | blup | 20 | 0.01 | 5.0e-02 | -5.2 | -5.3 | 1.3e-07 | 0.97 | 0.01 | 0.64 | FALSE |