Best TWAS P=2.89e-09 · Best GWAS P=1.22e-36 conditioned to 8.94e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C4orf22 | 0.09 | 0.08 | lasso | 5 | 0.07 | 4.5e-09 | 5.0 | 5.6 | 2.0e-08 | 0.59 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Adipose Visceral Omentum | PRDM8 | 0.29 | 0.01 | lasso | 3 | 0.01 | 1.2e-01 | -5.6 | -5.9 | 2.9e-09 | -0.18 | 0.09 | 0.06 | TRUE |
| 3 | GTEx | Nerve Tibial | PRDM8 | 0.14 | 0.14 | lasso | 3 | 0.13 | 1.0e-09 | -5.6 | -5.6 | 1.7e-08 | -0.19 | 1.00 | 0.00 | FALSE |