Best TWAS P=9.91e-08 · Best GWAS P=1.95e-07 conditioned to 0.965
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | CTSF | 0.11 | 0.00 | lasso | 1 | -0.01 | 6.7e-01 | -5.2 | -5.2 | 2.0e-07 | 1.00 | 0.01 | 0.27 | FALSE |
2 | GTEx | Colon Sigmoid | CTSF | 0.26 | 0.13 | enet | 6 | 0.15 | 4.4e-06 | -5.2 | -5.3 | 1.5e-07 | 0.90 | 0.00 | 0.96 | TRUE |
3 | GTEx | Esophagus Mucosa | C11orf80 | 0.27 | 0.07 | enet | 31 | 0.07 | 1.3e-05 | -5.2 | 5.3 | 9.9e-08 | -0.72 | 0.00 | 0.97 | TRUE |