Best TWAS P=2.56e-08 · Best GWAS P=3.45e-08 conditioned to 0.18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | NRBF2 | 0.09 | 0.04 | lasso | 6 | 0.03 | 1.6e-02 | 4.7 | 5.6 | 2.6e-08 | 0.87 | 0.05 | 0.62 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | REEP3 | 0.10 | 0.11 | lasso | 8 | 0.09 | 7.2e-12 | 5.0 | -5.2 | 2.1e-07 | -0.75 | 0.04 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | REEP3 | 0.04 | 0.04 | blup | 59 | 0.05 | 1.8e-06 | 5.1 | -5.2 | 2.5e-07 | -0.77 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | NRBF2 | 0.09 | 0.02 | enet | 6 | 0.04 | 1.4e-05 | 4.2 | 5.2 | 2.2e-07 | 0.64 | 0.01 | 0.98 | FALSE |