Best TWAS P=2.48e-30 · Best GWAS P=3.47e-39 conditioned to 3.85e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -8.2 | 9.2 | 3.7e-20 | -0.66 | 0.74 | 0.09 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 7.5 | 11.4 | 2.5e-30 | -0.48 | 0.99 | 0.01 | TRUE |