Best TWAS P=1.58e-11 · Best GWAS P=9.43e-15 conditioned to 0.00198
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LEPROT | 0.02 | 0.01 | blup | 51 | 0.01 | 0.00696 | 3.0 | 5.4 | 5.3e-08 | -0.05 | 0.03 | 0.09 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PDE4B | 0.03 | 0.00 | blup | 320 | 0.01 | 0.03510 | -6.6 | -6.7 | 1.6e-11 | 0.78 | 0.04 | 0.81 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LEPROT | 0.17 | 0.13 | enet | 15 | 0.10 | 0.00025 | 4.1 | 5.6 | 1.8e-08 | -0.10 | 0.08 | 0.19 | TRUE |