Best TWAS P=3.93e-13 · Best GWAS P=4.52e-13 conditioned to 0.00146
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | RP11-220I1.1 | 0.15 | 0 | lasso | 4 | 0.00 | 0.1590 | 6.4 | 5.3 | 1.1e-07 | -0.69 | 0.05 | 0.42 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PAX5 | 0.05 | 0 | blup | 204 | 0.02 | 0.0019 | 5.0 | -7.3 | 3.9e-13 | 0.67 | 0.01 | 0.86 | TRUE |