Best TWAS P=2.05e-07 · Best GWAS P=7.54e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | KCNJ11 | 0.04 | 0.03 | lasso | 3 | 0.03 | 0.00026 | -5.3 | -5.2 | 2.0e-07 | 0.96 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | DKFZp686O24166 | 0.04 | 0.01 | blup | 71 | 0.02 | 0.00150 | -4.2 | 5.1 | 2.9e-07 | -0.84 | 0.01 | 0.90 | FALSE |