[Hub]/) : Traits : BMI : ← →

chr11:26,693,196-29,054,545

Best TWAS P=4.66e-30 · Best GWAS P=9.15e-61 conditioned to 1.68e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 11.01 11.0 3.6e-28 -0.26 0.86 0.00 FALSE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 -9.62 10.8 2.4e-27 -0.65 0.05 0.81 FALSE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 11.01 8.3 8.3e-17 -0.06 1.00 0.00 FALSE
4 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 1.59 6.7 1.9e-11 0.10 0.80 0.03 FALSE
5 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 -1.07 -9.3 2.0e-20 0.27 0.09 0.11 FALSE
6 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 11.01 6.9 3.9e-12 -0.02 0.95 0.00 FALSE
7 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 11.01 10.4 2.6e-25 -0.14 0.81 0.01 FALSE
8 METSIM Adipose LGR4 0.03 0.01 enet 7 0.02 4.6e-04 -5.92 -5.8 8.9e-09 0.20 0.26 0.05 FALSE
9 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 11.92 -11.4 4.7e-30 0.17 0.52 0.01 TRUE
10 ROSMAP Brain Pre-frontal Cortex METTL15 0.04 0.03 blup 364 0.03 4.6e-05 -3.44 -7.2 7.5e-13 0.26 0.69 0.05 TRUE
11 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 11.62 7.4 1.3e-13 0.12 0.17 0.19 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 11.57 9.8 1.4e-22 -0.11 0.29 0.26 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma BDNFOS 0.03 0.01 blup 83 0.02 1.4e-03 -0.42 8.8 1.3e-18 -0.76 0.01 0.96 TRUE