[Hub]/) : Traits : BMI :

chr11:29,646,947-32,824,150

Best TWAS P=6.46e-13 · Best GWAS P=1.82e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RCN1 0.19 0.13 lasso 5 0.15 1.1e-17 -5.1 -5.2 2.5e-07 -0.03 0.01 0.99 FALSE
2 GTEx Artery Aorta ARL14EP 0.16 0.02 lasso 5 0.05 7.4e-04 -7.7 -6.2 4.6e-10 0.47 0.37 0.31 FALSE
3 GTEx Brain Cerebellum ARL14EP 0.33 0.25 lasso 10 0.26 3.7e-08 6.2 -6.5 1.0e-10 0.40 0.97 0.00 FALSE
4 GTEx Cells Transformed fibroblasts RCN1 0.31 0.23 lasso 4 0.24 5.8e-18 -5.4 -5.6 1.9e-08 -0.04 0.00 1.00 TRUE
5 GTEx Colon Sigmoid ARL14EP 0.16 0.05 lasso 13 0.10 2.6e-04 5.8 -6.0 1.4e-09 0.51 0.09 0.59 FALSE
6 GTEx Esophagus Gastroesophageal Junction ARL14EP 0.15 0.14 lasso 3 0.11 1.2e-04 6.2 -6.3 3.3e-10 0.39 0.57 0.04 TRUE
7 GTEx Esophagus Mucosa ARL14EP 0.09 0.03 enet 11 0.05 1.8e-04 5.8 -5.6 2.2e-08 0.49 0.31 0.32 TRUE
8 GTEx Esophagus Muscularis ARL14EP 0.18 0.20 lasso 8 0.19 9.5e-12 6.4 -7.2 6.7e-13 0.46 1.00 0.00 TRUE
9 GTEx Lung ARL14EP 0.10 0.06 lasso 8 0.11 1.1e-08 -3.3 -7.0 2.2e-12 0.71 0.31 0.69 FALSE
10 GTEx Nerve Tibial ARL14EP 0.19 0.17 enet 22 0.18 4.2e-13 6.3 -6.5 7.9e-11 0.46 1.00 0.00 TRUE
11 GTEx Ovary ARL14EP 0.35 0.21 enet 31 0.18 2.8e-05 6.4 -5.3 8.7e-08 0.36 0.18 0.18 TRUE
12 GTEx Pancreas ARL14EP 0.16 0.08 lasso 6 0.07 1.0e-03 5.6 -6.5 1.1e-10 0.39 0.16 0.52 FALSE
13 GTEx Pituitary ARL14EP 0.30 0.28 lasso 4 0.22 3.0e-06 7.0 -7.2 6.5e-13 0.55 0.44 0.10 FALSE
14 GTEx Spleen ARL14EP 0.34 0.19 enet 24 0.30 1.7e-08 2.3 -5.5 3.6e-08 0.68 0.11 0.80 TRUE
15 GTEx Thyroid RCN1 0.16 0.09 enet 23 0.11 6.9e-09 3.8 -5.3 1.2e-07 -0.07 0.41 0.54 FALSE
16 GTEx Thyroid ARL14EP 0.20 0.05 lasso 6 0.09 1.0e-07 -2.1 -6.2 5.3e-10 0.50 0.90 0.10 TRUE
17 METSIM Adipose RCN1 0.09 0.09 lasso 2 0.09 2.6e-13 -5.2 -5.2 1.7e-07 -0.05 0.01 0.99 FALSE
18 ROSMAP Brain Pre-frontal Cortex MPPED2 0.25 0.29 lasso 7 0.29 4.4e-37 6.5 -6.6 5.1e-11 0.54 1.00 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex ARL14EP 0.08 0.07 enet 13 0.08 5.3e-10 6.4 -6.0 1.5e-09 0.35 1.00 0.00 FALSE
20 The Cancer Genome Atlas Lung Adenocarcinoma MPPED2 0.07 0.01 blup 149 0.03 7.0e-05 7.0 -5.3 9.8e-08 0.38 0.32 0.26 TRUE