Best TWAS P=1.25e-08 · Best GWAS P=9.16e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | SMCO4 | 0.29 | 0.24 | lasso | 7 | 0.20 | 1.2e-09 | -5.7 | 5.7 | 1.2e-08 | -0.98 | 0 | 1.00 | TRUE |
| 2 | GTEx | Thyroid | SMCO4 | 0.11 | 0.02 | enet | 7 | 0.00 | 4.1e-01 | 4.8 | 5.5 | 3.4e-08 | -0.94 | 0 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SMCO4 | 0.08 | 0.07 | lasso | 4 | 0.08 | 6.4e-11 | -5.7 | 5.4 | 7.4e-08 | -0.91 | 0 | 1.00 | FALSE |