Best TWAS P=2.9e-13 · Best GWAS P=1.54e-24 conditioned to 0.031
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RAD52 | 0.14 | 0.07 | lasso | 3 | 0.10 | 1.1e-05 | -6.1 | -6.8 | 1.1e-11 | -0.44 | 0.54 | 0.37 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | RAD52 | 0.46 | 0.04 | lasso | 9 | 0.06 | 1.4e-02 | -5.5 | 5.3 | 1.5e-07 | 0.22 | 0.07 | 0.09 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RAD52 | 0.13 | 0.11 | lasso | 6 | 0.14 | 2.1e-11 | -4.5 | -5.2 | 2.6e-07 | -0.31 | 1.00 | 0.00 | TRUE |
| 4 | NTR | Blood | WNK1 | 0.02 | 0.00 | blup | 453 | 0.01 | 3.9e-04 | -5.9 | 7.3 | 2.9e-13 | 0.35 | 0.06 | 0.21 | TRUE |
| 5 | The Cancer Genome Atlas | Glioblastoma Multiforme | RAD52 | 0.17 | 0.01 | blup | 66 | 0.02 | 9.9e-02 | -3.4 | 5.6 | 1.9e-08 | 0.11 | 0.02 | 0.09 | TRUE |
| 6 | The Cancer Genome Atlas | Glioblastoma Multiforme | WNK1 | 0.19 | 0.07 | blup | 81 | 0.07 | 2.8e-03 | 2.7 | 5.3 | 1.2e-07 | 0.11 | 0.05 | 0.05 | TRUE |