Best TWAS P=9.96e-13 · Best GWAS P=1.21e-23 conditioned to 7.49e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PTBP2 | 0.08 | 0.06 | lasso | 10 | 0.08 | 4.6e-10 | -1.01 | -5.6 | 2.4e-08 | 0.44 | 0.99 | 0.01 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | EEF1A1P11 | 0.12 | 0.00 | enet | 24 | 0.03 | 8.2e-02 | 0.61 | 5.9 | 4.3e-09 | -0.46 | 0.03 | 0.27 | TRUE |
| 3 | GTEx | Nerve Tibial | PTBP2 | 0.20 | 0.16 | lasso | 8 | 0.14 | 6.4e-10 | 7.71 | 7.1 | 1.0e-12 | -0.14 | 1.00 | 0.00 | TRUE |
| 4 | METSIM | Adipose | PTBP2 | 0.08 | 0.05 | lasso | 4 | 0.04 | 1.3e-06 | 7.71 | 5.6 | 2.2e-08 | 0.04 | 0.98 | 0.00 | TRUE |