TWAS hub - PTBP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0810	0.0220	2.0e-08	0.063	0.067	0.043	0.071	0.081	4.1e-08	1.4e-08	5.6e-06	5.6e-09	4.6e-10
2	GTEx	Breast Mammary Tissue	0.2420	0.0730	2.2e-05	0.129	NA	0.099	NA	0.123	3.8e-07	NA	9.1e-06	NA	7.0e-07
3	GTEx	Breast Mammary Tissue (Female)	0.1593	0.0999	6.7e-02	0.007	NA	-0.010	NA	-0.008	1.9e-01	NA	9.9e-01	NA	6.7e-01
4	GTEx	Cells EBV-transformed lymphocytes	0.2470	0.0780	9.4e-04	0.142	NA	0.025	NA	0.099	2.3e-05	NA	5.2e-02	NA	3.9e-04
5	GTEx	Cells Transformed fibroblasts	0.1840	0.0460	4.5e-06	0.098	NA	0.105	NA	0.097	8.2e-08	NA	3.0e-08	NA	9.6e-08
6	GTEx	Lung	0.0891	0.0369	3.2e-03	0.033	NA	0.003	NA	0.025	1.5e-03	NA	1.6e-01	NA	4.9e-03
7	GTEx	Nerve Tibial	0.1979	0.0490	3.1e-09	0.162	NA	0.117	NA	0.137	1.4e-11	NA	1.3e-08	NA	6.4e-10
8	METSIM	Adipose	0.0775	0.0274	8.0e-06	0.048	0.032	0.035	0.038	0.039	1.0e-07	1.3e-05	5.1e-06	1.9e-06	1.3e-06
9	ROSMAP	Brain Pre-frontal Cortex	0.0491	0.0183	5.0e-04	0.007	0.018	0.012	0.017	0.001	4.0e-02	2.0e-03	1.0e-02	2.2e-03	1.9e-01
10	YFS	Blood	0.1457	0.0291	0.0e+00	0.140	0.162	0.166	0.169	0.167	1.7e-43	1.5e-50	7.3e-52	7.7e-53	2.5e-52
11	TCGA	Brain Lower Grade Glioma	0.0344	0.0208	9.6e-04	0.017	0.022	0.020	NA	0.024	4.0e-03	1.5e-03	1.9e-03	NA	9.4e-04
12	TCGA	Lung Adenocarcinoma	0.0545	0.0281	5.6e-05	0.016	0.012	0.031	NA	0.014	5.2e-03	1.2e-02	1.2e-04	NA	8.0e-03
13	TCGA	Pancreatic Adenocarcinoma	0.1000	0.0540	3.8e-04	0.024	0.064	0.045	NA	0.036	3.4e-02	1.1e-03	5.5e-03	NA	1.2e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Average weekly champagne plus white wine intake	5.5	7.6	12.6	0.4	3.5	3.5	3.5	-1.2	3.2	2.6	2.0	2.0	3.4	2.4	2.4	3.5
Headache pain in last month	5.4	9.3	13.8	-0.8	-3.5	-2.6	-3.7	1.5	-3.7	-3.0	-2.7	-3.3	-3.6	-3.0	-3.1	-3.6
Pain experienced in last month	5.1	8.5	14.4	0.5	3.4	2.7	3.8	0.4	3.8	3.2	2.5	2.6	2.9	2.7	3.6	3.2
Mouth/teeth dental problems: Loose teeth	5.0	5.9	11.2	1.5	1.6	1.0	1.7	-1.9	2.3	2.1	3.1	3.3	2.4	3.1	3.3	2.8
Ever had stillbirth, spontaneous miscarriage or termination	5.0	5.3	8.2	1.2	2.9	2.5	2.6	0.1	2.7	2.3	2.2	2.7	2.6	2.5	1.7	2.5
Frequency of tiredness / lethargy in last 2 weeks	4.8	7.8	14.7	-0.6	-3.5	-2.4	-3.8	1.4	-3.4	-3.2	-2.0	-1.7	-3.1	-3.0	-3.1	-3.1
Reason for reducing amount of alcohol drunk: Health precaution	4.6	5.3	8.7	1.7	1.9	2.0	2.1	-0.7	2.2	2.1	2.4	2.8	2.6	2.8	3.0	2.7
Had menopause	4.5	5.6	10.5	0.5	-2.8	-3.0	-2.8	1.8	-3.1	-1.5	-1.1	-3.2	-2.5	-1.6	-2.3	-2.7
Relative age voice broke	4.1	6.3	15.9	-2.7	-1.8	-3.8	-1.5	4.0	-1.7	-0.3	-0.7	-1.8	-3.6	-2.5	-1.7	-3.2
Chronic bronchitis/emphysema (mother)	3.8	4.5	6.9	-1.1	-2.1	-2.6	-2.1	-0.4	-2.5	-2.0	-2.5	-1.8	-2.3	-2.3	-2.1	-2.5
Qualifications: NVQ or HND or HNC or equivalent	3.8	4.6	6.8	-1.3	-2.6	-2.0	-2.0	0.8	-1.8	-2.5	-2.5	-2.6	-2.5	-2.1	-2.0	-2.2
Body Mass Index (BMI) (2010)	3.7	5.1	14.1	-1.2	2.9	0.5	2.9	3.0	2.5	3.8	3.1	0.4	0.4	1.6	2.1	1.4
Gout (self-reported)	3.7	5.0	12.7	-3.0	-1.6	-0.9	-1.7	0.3	-1.8	-2.0	-2.5	-1.6	-2.6	-3.6	-2.8	-2.5
Comparative body size at age 10	3.6	9.9	24.9	-0.5	3.7	1.1	4.1	2.5	4.1	5.0	4.3	-0.0	1.5	3.3	3.5	2.2
Average weekly spirits intake	3.5	4.3	13.5	-0.5	2.0	0.1	2.5	2.6	2.8	3.7	2.9	0.5	0.4	2.0	1.9	1.1
Reaction Time	3.4	6.5	37.3	6.1	-1.8	-1.1	-1.0	-0.5	0.2	-0.2	2.3	1.7	2.7	3.7	2.2	2.6
Had major operations	3.4	4.0	5.9	1.5	2.4	2.4	2.3	1.7	2.4	2.2	1.9	0.8	1.9	1.9	2.0	1.8
Neck or shoulder pain in last month	3.0	4.3	11.7	0.6	-2.7	-1.9	-2.9	-1.1	-2.5	-3.4	-2.5	-0.5	-1.3	-1.8	-2.0	-1.6
Loud music exposure frequency	2.9	3.2	8.0	1.9	1.4	2.8	1.1	-1.4	1.3	0.4	1.0	2.6	2.4	1.6	1.1	2.4
Worry (Nagel 2018)	2.8	5.9	15.0	2.3	-3.9	-3.5	-3.8	0.3	-3.2	-2.3	-0.8	-0.9	-1.9	-0.4	-2.0	-2.1
Schizophrenia (2014)	2.8	6.1	17.9	4.2	1.0	2.5	1.1	-0.5	1.3	0.4	1.5	3.6	3.5	2.7	2.3	3.3
Worry too long after embarrassment	2.8	4.6	18.3	0.4	-2.1	-2.6	-1.8	4.3	-1.9	-1.3	-1.3	-2.7	-1.9	-1.3	-1.7	-2.1
Wears glasses or contact lenses	2.8	3.2	9.2	-0.7	-1.6	-1.9	-1.9	0.3	-2.6	-1.4	-0.8	-3.0	-1.9	-1.7	-1.6	-2.0
Crohns Disease (2012)	2.7	4.3	8.6	0.5	-2.5	-1.7	-2.7	0.0	-2.6	-2.9	-2.4	-0.6	-1.6	-1.9	-2.9	-1.8
BMI	2.7	15.6	50.8	-5.6	4.2	-0.4	4.5	4.2	4.5	7.1	5.6	-1.5	-2.0	1.3	2.2	0.1
Current tobacco smoking	2.7	4.4	9.0	0.6	2.3	0.8	2.5	0.8	2.7	3.0	2.6	1.8	1.3	2.6	2.3	1.9
Number of incorrect matches in round	2.7	4.4	11.2	2.2	1.5	1.0	2.2	-1.5	1.9	1.4	0.5	3.3	3.2	2.4	1.3	2.9
Hearing difficulty/problems with background noise	2.7	4.4	14.8	-1.8	-1.7	-3.9	-1.9	1.1	-1.5	-0.6	-0.6	-1.8	-3.2	-1.7	-2.0	-2.8
Back pain experienced in last month	2.7	3.9	7.6	-0.0	-2.2	-1.3	-2.6	-0.8	-2.3	-2.5	-2.0	-1.9	-1.6	-1.9	-2.8	-1.9
Smoking Status	2.6	6.2	12.3	-0.3	3.4	1.9	3.3	3.3	3.5	3.4	2.3	1.4	1.0	2.2	1.7	2.0
Smoking status: Current	2.6	4.1	8.6	0.5	2.3	0.9	2.5	1.1	2.6	2.9	2.4	1.9	1.3	2.5	2.1	1.8
Neuroticism (Nagel 2018)	2.5	5.8	16.1	1.8	-3.7	-4.0	-3.4	2.0	-2.8	-1.8	-0.2	-1.4	-2.5	-0.6	-1.5	-2.3
Diverticular disease/diverticulitis (self-reported)	2.5	3.0	5.1	-1.9	-1.2	-1.1	-0.9	2.2	-1.4	-1.0	-1.6	-2.1	-2.3	-2.2	-1.5	-2.2
Medication: Allopurinol	2.5	3.4	8.6	-2.6	-1.2	-1.2	-1.4	-0.2	-1.4	-1.9	-2.0	-0.6	-2.2	-2.9	-2.1	-2.1
Medication: Amlodipine	2.4	3.3	5.8	1.6	1.8	1.1	1.7	-1.0	2.0	1.5	1.8	1.8	2.0	2.2	2.0	2.4
Mean time to correctly identify matches	2.4	4.6	26.8	5.2	-2.1	-2.2	-1.4	-0.4	-0.6	-0.7	1.6	0.7	2.1	2.8	1.1	1.8
Supplements: Calcium	2.4	2.6	4.3	1.1	2.0	2.0	1.3	-1.1	1.8	0.9	1.3	1.9	2.1	1.5	1.3	2.1
Impedance of arm (left)	2.3	10.9	28.2	2.8	-4.4	-2.9	-4.8	-1.5	-4.7	-5.3	-3.5	-1.2	-1.2	-1.7	-3.0	-1.9
Townsend deprivation index at recruitment	2.2	3.1	8.9	0.4	2.0	-0.7	2.2	1.1	3.0	1.9	1.5	2.0	1.1	2.0	1.5	1.7
Worrier / anxious feelings	2.2	4.1	10.7	1.8	-3.3	-2.2	-3.0	2.0	-2.6	-2.1	-1.2	-0.7	-1.6	-0.8	-1.7	-1.7
Ever highly irritable/argumentative for 2 days	2.2	2.6	4.4	-0.8	-1.9	-1.0	-2.0	-1.3	-1.6	-2.1	-1.9	0.3	-1.8	-1.9	-1.8	-1.6
Eye problems/disorders: None of the above	2.2	2.5	5.8	1.7	1.2	2.1	1.0	-1.5	1.2	-0.0	0.3	1.8	2.4	2.0	0.9	2.2
Commuting to job workplace: Public transport	2.2	2.7	6.0	-0.4	2.4	1.7	2.4	0.9	2.2	1.3	0.6	2.2	1.6	0.8	1.1	1.7
Medication for pain relief, constipation, heartburn	2.1	3.6	7.2	0.0	2.7	2.7	2.2	-1.3	2.0	0.8	0.4	2.4	2.6	1.1	1.5	2.3
Age at last live birth	2.1	3.1	10.6	3.3	0.0	1.6	0.1	1.2	0.7	-0.2	1.0	2.9	2.3	1.7	1.7	2.2
Ever had bowel cancer screening	2.1	2.5	4.7	1.3	-1.9	-1.2	-2.1	0.5	-2.2	-1.7	-1.4	-1.8	-1.1	-0.7	-2.0	-1.5
Age started oral contraceptive pill	2.1	2.7	6.3	2.1	-2.5	-1.4	-2.2	-0.3	-2.1	-2.0	-1.6	-1.2	0.0	-0.5	-2.0	-0.5
Impedance of whole body	2.1	10.5	26.9	3.0	-4.5	-2.6	-4.8	-1.0	-4.6	-5.2	-3.6	-0.9	-1.1	-1.6	-2.8	-1.9
Hearing difficulty/problems: Yes	2.0	3.0	7.8	-1.7	-1.4	-2.4	-1.7	1.4	-1.5	-0.4	0.0	-1.3	-2.8	-1.9	-1.4	-2.4
Fed-up feelings	2.0	3.7	9.3	-1.3	-2.4	-2.7	-2.5	-0.0	-2.1	-1.1	-0.3	-1.2	-3.0	-1.6	-1.3	-2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	11.4	1.5	-1.7	-2.6	-1.7	3.4	-1.7	-0.1	0.8	-1.3	-2.0	-0.3	-0.9	-1.8
Eye problems/disorders: Cataract	2.0	2.3	5.2	-1.5	-1.5	-2.3	-1.3	1.3	-1.3	-0.7	-0.8	-1.4	-2.0	-1.8	-1.3	-1.9
Past tobacco smoking	1.9	3.5	12.5	0.9	-2.6	-1.0	-2.1	-3.5	-2.2	-2.5	-2.1	-1.1	-0.1	-1.1	-0.9	-0.7
Leg fat mass (right)	1.9	7.2	25.7	-5.1	2.1	-1.3	2.2	3.0	2.2	4.4	3.2	-1.8	-2.8	-0.3	0.5	-1.2
Crohns Disease (2017)	1.8	4.0	7.4	-0.4	-2.4	-1.4	-2.3	-0.1	-2.6	-2.7	-2.6	-1.2	-1.5	-2.1	-2.7	-1.7
Trunk fat percentage	1.8	7.4	21.7	-4.2	-0.8	-3.6	-0.9	3.5	-0.6	1.3	1.3	-3.3	-4.7	-1.8	-1.7	-3.2
Stomach or abdominal pain in last month	1.8	2.2	4.5	0.6	-1.8	-1.8	-2.0	2.1	-1.6	-1.2	-0.3	-1.1	-1.7	-0.8	-1.4	-1.8
Body mass index (BMI)	1.8	7.8	25.8	-5.1	2.1	-1.7	2.2	3.2	2.5	4.6	3.6	-1.4	-3.0	-0.1	0.7	-1.2
Hip circumference	1.8	7.8	26.1	-5.1	1.7	-1.7	1.7	4.3	1.3	3.7	2.5	-3.1	-3.4	-1.0	-0.2	-2.1
Arm fat mass (right)	1.8	7.3	23.3	-4.8	1.7	-2.0	1.8	3.8	2.0	4.0	3.2	-2.1	-3.2	-0.4	0.1	-1.5
Illnesses of father: Heart disease	1.8	2.5	9.8	-1.5	1.2	-1.4	1.6	3.1	0.8	2.8	1.5	-1.6	-1.2	-0.1	0.1	-0.5
Leg fat mass (left)	1.8	6.9	24.3	-4.9	1.9	-1.2	2.0	3.5	2.1	4.1	3.1	-1.7	-2.9	-0.4	0.3	-1.3
Depression (Nagel 2018)	1.7	2.6	5.9	1.6	-2.3	-2.2	-2.4	1.8	-1.8	-1.3	0.2	-0.8	-1.6	-0.8	-0.7	-1.5
Ever had hysterectomy (womb removed)	1.7	2.0	4.4	0.1	-1.6	-1.2	-1.7	-2.1	-1.9	-1.5	-1.3	-1.4	-0.6	-1.0	-1.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.8	15.1	-1.6	2.4	3.9	2.5	-0.2	2.4	1.4	0.6	2.1	1.5	0.1	0.7	2.0
Trunk fat mass	1.7	7.2	22.9	-4.8	0.5	-2.6	0.5	3.9	0.7	2.7	2.2	-3.0	-4.2	-1.3	-0.9	-2.6
Had other major operations	1.7	2.1	4.5	-0.0	2.1	1.4	1.9	1.9	2.1	2.0	1.5	0.3	0.7	1.2	0.6	0.8
Happiness	1.7	2.1	4.9	0.4	-2.2	-1.2	-2.1	0.9	-1.7	-1.1	-0.2	-0.6	-2.1	-1.1	-0.7	-2.0
Arm fat mass (left)	1.7	7.0	24.2	-4.9	1.3	-2.1	1.3	3.8	1.5	3.6	2.9	-2.2	-3.6	-0.8	-0.3	-1.8
Pain type(s) experienced in last month: Hip pain	1.7	2.2	4.2	-0.4	-1.5	-1.0	-1.9	0.4	-1.8	-1.9	-1.7	-1.0	-1.4	-1.4	-2.0	-1.4
Arm predicted mass (left)	1.7	8.5	23.7	-4.0	3.8	1.8	4.1	2.8	3.8	4.9	3.2	-0.3	-0.4	0.6	1.9	0.6
Alzheimer’s Disease (in mother)	1.6	1.9	5.1	1.2	1.9	1.3	1.6	1.1	1.5	0.4	0.1	0.8	2.2	1.0	0.3	2.1
Impedance of arm (right)	1.6	7.7	22.6	3.2	-3.6	-2.1	-4.0	-1.1	-3.9	-4.8	-2.9	-0.9	-0.3	-1.0	-2.4	-1.0
Trunk fat-free mass	1.6	9.1	24.1	-3.3	4.2	2.5	4.6	2.3	4.1	4.9	3.0	0.1	0.5	1.0	2.3	1.2
Illnesses of mother	1.6	2.0	4.2	0.6	0.7	2.0	0.9	-0.9	2.0	0.8	1.5	2.0	1.2	1.3	1.6	1.4
Trunk predicted mass	1.6	9.1	23.9	-3.4	4.2	2.5	4.6	2.2	4.1	4.9	3.0	0.1	0.4	1.0	2.3	1.1
Body fat percentage	1.6	6.4	17.7	-4.2	-0.2	-3.3	-0.2	3.3	0.2	2.2	2.0	-2.8	-4.2	-1.2	-1.1	-2.6
Heart disease (mother)	1.6	2.0	3.3	-0.8	-1.0	-1.2	-1.3	1.6	-1.8	-1.3	-1.4	-1.7	-1.4	-1.5	-1.7	-1.4
Whole body fat mass	1.6	6.7	22.4	-4.7	0.8	-2.3	0.8	3.7	1.0	3.0	2.5	-2.7	-3.8	-1.0	-0.7	-2.3
Number of full sisters	1.6	1.9	10.2	-3.2	1.4	-1.5	1.4	0.6	0.9	1.7	0.4	-0.8	-1.6	-0.8	-0.2	-0.7
Arm fat-free mass (left)	1.6	8.0	22.3	-4.0	3.6	1.7	3.9	2.6	3.7	4.7	3.0	-0.4	-0.6	0.5	1.7	0.5
Number of operations (self-reported)	1.6	2.4	7.8	0.0	2.0	1.3	1.8	2.8	2.3	1.8	1.8	0.4	0.8	0.8	0.9	1.1
Heart disease (siblings)	1.6	2.0	4.8	-2.0	-0.5	-1.6	-0.7	1.4	-1.0	0.1	-0.3	-2.1	-2.2	-1.8	-0.9	-1.7
Mean Putamen Volume	1.5	1.7	5.5	-1.6	-1.2	-2.3	-1.2	-1.2	-1.1	-0.4	-0.2	-0.4	-2.1	-0.9	-0.5	-1.6
Neuroticism (2016)	1.5	2.2	4.9	0.7	-2.2	-1.9	-2.2	1.4	-1.6	-1.7	-0.9	-1.3	-1.4	-0.9	-0.7	-1.2
Weight	1.5	7.6	27.7	-5.3	2.3	-0.9	2.5	3.5	2.4	4.3	3.0	-2.0	-2.8	-0.5	0.4	-1.3
Tense / ‘highly strung’	1.5	2.4	5.6	-0.6	-2.1	-1.9	-2.1	-1.2	-1.4	-1.2	-0.9	0.3	-2.4	-0.9	-1.8	-1.8
Arm fat-free mass (right)	1.5	7.5	22.0	-3.9	3.4	1.6	3.8	2.6	3.5	4.7	2.9	-0.3	-0.6	0.4	1.7	0.3
Wheeze or whistling in the chest in last year	1.5	2.6	5.9	-0.4	1.8	0.3	1.8	1.0	2.1	2.4	2.4	1.8	0.7	1.5	1.4	1.4
Number of children fathered	1.5	1.7	9.5	-3.1	0.7	0.8	0.4	-0.2	-0.7	0.2	-1.0	-0.9	-1.7	-1.9	-0.7	-1.4
Arm predicted mass (right)	1.5	7.8	22.9	-3.8	3.6	1.7	3.9	2.5	3.6	4.8	3.1	-0.4	-0.4	0.6	1.8	0.5
Medication: Aspirin	1.5	2.0	9.7	0.7	-1.9	-3.1	-1.7	0.1	-1.2	-0.5	-0.2	-1.2	-1.8	-0.3	-0.9	-1.3
Whole body fat-free mass	1.5	8.3	22.8	-3.8	3.9	2.0	4.2	2.5	3.8	4.8	3.0	-0.3	-0.1	0.7	1.8	0.8
Supplements: Fish oil (including cod liver oil)	1.5	1.9	4.7	-0.2	1.8	2.0	2.2	-0.8	1.4	0.9	-0.2	1.0	1.9	0.7	0.8	1.9
Medication: Bendroflumethiazide	1.5	2.3	4.9	-2.0	-0.7	-1.2	-1.0	0.7	-1.1	-0.3	-0.7	-2.2	-2.2	-1.8	-1.8	-2.0
Ever smoked	1.5	2.7	12.8	0.4	1.9	0.7	1.5	3.6	2.0	2.0	1.7	1.1	0.5	1.5	0.7	0.9
Basal cell carcinoma (self-reported)	1.5	1.8	2.9	1.0	1.4	1.4	1.5	0.9	1.4	1.1	1.0	1.6	1.6	1.4	1.2	1.7
Age at First Birth	1.4	2.0	7.7	2.8	0.0	1.6	-0.1	0.5	1.1	-0.7	0.3	1.7	2.1	1.5	0.8	1.8
Neuroticism	1.4	3.4	11.0	1.9	-2.7	-3.3	-2.6	2.1	-1.8	-1.1	0.3	-0.9	-1.7	0.3	-0.8	-1.5
Diabetes (father)	1.4	1.7	5.3	-2.3	-0.5	-1.4	-0.9	0.9	-1.3	-0.3	-0.2	-1.1	-1.8	-1.7	-1.4	-1.4
Waist circumference	1.4	5.0	13.8	-3.7	1.9	-0.8	1.7	3.1	1.9	3.6	3.2	-1.1	-2.4	0.1	0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	14.5	-1.2	2.0	3.8	2.1	-0.5	1.8	1.1	0.5	2.4	1.8	0.0	0.6	2.2
Arm fat percentage (right)	1.4	5.4	14.8	-3.8	0.8	-2.7	0.7	3.4	1.1	2.9	2.8	-2.1	-3.3	-0.3	-0.2	-1.6
Leg fat percentage (right)	1.4	5.0	16.7	-4.1	1.1	-2.1	1.3	2.3	1.5	3.6	2.9	-1.5	-2.9	-0.1	0.2	-1.4
Migraine (self-reported)	1.4	1.7	4.9	-0.4	-1.0	-0.3	-1.2	0.6	-1.9	-1.1	-1.2	-2.2	-1.2	-1.6	-1.3	-1.6
Medication: Omeprazole	1.4	1.6	3.5	-0.5	-1.2	-1.1	-1.4	1.7	-1.3	-0.4	-0.1	-1.7	-1.9	-1.2	-1.2	-1.5
Illnesses of siblings: Diabetes	1.4	1.8	4.4	-0.9	1.6	0.8	1.3	0.7	1.6	2.0	2.1	1.5	-0.1	0.6	1.5	0.5
Arm fat percentage (left)	1.4	5.7	17.0	-4.1	0.4	-2.9	0.3	3.2	0.7	2.6	2.5	-2.3	-3.7	-0.8	-0.6	-2.1
Friendships satisfaction	1.4	1.8	4.6	-1.1	-0.8	-2.1	-0.6	1.7	-0.9	0.3	-0.2	-1.0	-2.2	-1.2	-1.2	-1.9
Whole body water mass	1.4	8.0	21.7	-3.8	3.8	2.0	4.1	2.5	3.7	4.7	3.0	-0.4	-0.2	0.6	1.8	0.7
Basal metabolic rate	1.4	8.0	22.6	-4.2	3.6	1.4	3.9	2.8	3.6	4.8	3.1	-0.7	-0.8	0.4	1.6	0.3
Myopia	1.4	2.1	4.3	1.8	1.3	1.4	0.9	0.1	1.2	1.0	1.5	2.1	1.9	1.6	1.0	1.7
Lupus	1.3	2.0	6.0	0.9	-2.5	-1.4	-1.9	1.8	-1.2	-2.0	-1.3	-0.1	-0.5	-0.9	-1.1	-0.6
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	4.4	0.6	-2.0	-2.1	-2.1	0.0	-1.7	-1.2	-0.5	0.2	-1.7	-0.8	-1.5	-1.8
Overall health rating	1.3	2.7	6.9	0.2	-2.1	-2.6	-2.2	1.6	-1.5	-0.7	0.7	-1.5	-2.3	-0.7	-1.5	-1.6
Leg pain on walking	1.3	1.6	4.5	-0.7	-1.1	-1.1	-1.3	0.0	-1.7	-0.8	-0.3	-1.2	-1.5	-1.4	-2.1	-1.5
Mother’s age at death	1.3	1.7	4.0	0.3	-1.2	-0.4	-1.2	0.8	-1.5	-1.8	-2.0	-1.4	-0.5	-1.5	-1.8	-1.1
Leg fat percentage (left)	1.3	4.7	15.1	-3.9	1.1	-1.8	1.1	2.6	1.5	3.4	3.0	-1.2	-2.8	-0.2	0.4	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.5	-0.4	-1.3	-1.7	-1.3	1.4	-1.2	-0.1	0.1	-1.5	-1.9	-1.0	-1.5	-1.6
Schizophrenia vs Biploar Disorder	1.2	1.5	5.3	2.3	-1.4	0.4	-1.6	-0.7	-1.4	-2.1	-1.1	0.5	0.3	-0.5	-1.1	0.2
Allergy or Eczema	1.2	3.1	6.1	-0.5	-1.6	-0.5	-1.9	-0.3	-2.5	-2.2	-2.3	-1.4	-1.9	-2.1	-1.7	-2.2
Supplements: Zinc	1.2	1.3	5.9	0.3	1.0	0.6	0.9	-2.4	0.7	-0.1	-0.7	1.5	1.7	0.6	0.8	1.3
Medication: Co-codamol	1.2	1.4	9.6	-0.5	0.3	-1.4	0.7	3.1	0.9	1.4	0.5	-1.3	-0.7	0.1	0.1	-0.5
Leg fat-free mass (left)	1.2	6.4	19.9	-4.5	3.0	1.0	3.2	2.6	2.9	4.0	2.5	-1.4	-1.2	-0.1	0.9	-0.2
Leg predicted mass (left)	1.2	6.4	19.7	-4.4	3.0	1.0	3.2	2.6	2.9	4.1	2.6	-1.4	-1.2	-0.1	0.9	-0.1
Prospective memory result	1.2	1.5	5.3	2.3	-0.0	0.3	0.4	-1.7	0.7	0.5	0.5	1.2	1.7	1.8	0.6	1.6
Medication: Gliclazide	1.2	1.3	3.5	-1.8	-0.2	-0.1	0.2	1.9	-0.4	-0.0	-1.0	-1.8	-0.9	-1.5	-1.2	-1.0
Commuting to job workplace: Cycle	1.2	1.4	3.4	0.2	1.3	1.9	1.4	-0.9	1.3	0.8	0.6	1.4	1.5	0.9	0.9	1.5
Depressed Affect (Nagel 2018)	1.1	2.4	9.0	0.7	-2.3	-3.0	-2.3	1.4	-1.4	-1.1	0.3	-0.4	-1.8	-0.3	-0.7	-1.4
Ever used hormone-replacement therapy (HRT)	1.1	1.3	3.1	-0.8	-0.7	-1.3	-0.8	0.2	-1.5	-0.4	-0.9	-1.7	-1.1	-1.4	-1.8	-1.4
Angina	1.1	1.4	3.4	0.4	1.5	0.8	1.2	-0.2	0.9	1.3	1.7	1.3	0.9	1.2	1.8	1.2
Emphysema/chronic bronchitis	1.1	1.3	4.5	0.8	-1.4	-1.1	-1.3	-0.5	-1.1	-2.1	-1.9	-0.7	-0.1	-0.7	-0.8	-0.2
Smoking status: Previous	1.1	1.6	8.1	-0.8	1.9	0.6	1.2	2.8	1.2	1.6	1.5	0.2	-0.2	0.5	0.7	0.3
Leg fat-free mass (right)	1.1	6.0	15.4	-3.8	3.1	1.4	3.2	2.4	3.1	3.9	2.8	-0.8	-0.8	0.2	1.2	0.2
Leg predicted mass (right)	1.1	6.0	15.0	-3.8	3.1	1.4	3.2	2.5	3.1	3.9	2.7	-0.9	-0.8	0.2	1.2	0.2
Alcohol drinker status: Previous	1.1	1.3	3.6	1.5	0.4	1.3	0.5	-0.5	0.8	0.2	0.9	1.9	1.4	1.4	1.2	1.2
Schizophrenia (2018)	1.0	2.1	13.8	3.7	-0.4	0.8	-0.5	0.4	-0.2	-0.8	0.3	1.4	1.9	1.5	0.5	1.7
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.3	1.2	0.3	-0.9	-0.0	1.6	0.3	1.2	1.8	1.3	0.7	1.4	1.2	0.7
Chronotype (morning person)	1.0	2.4	9.0	-3.0	1.8	0.3	1.7	-2.9	0.7	2.0	1.3	0.3	-0.0	0.3	1.1	0.3
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.2	-0.8	1.4	-0.3	1.3	2.3	1.2	1.6	0.7	-0.2	-0.2	0.4	0.3	0.3
Medication for hormone replacement therapy	1.0	1.1	3.4	-1.7	1.7	-0.3	1.6	0.6	1.0	1.8	0.8	-0.5	-0.1	0.1	-0.3	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	6.3	0.4	-1.1	-2.5	-1.0	1.7	-0.3	0.4	1.1	-0.1	-1.7	0.2	0.4	-1.1
Alcohol usually taken with meals	1.0	1.5	4.1	-1.0	-0.8	0.4	-1.1	-0.9	-2.0	-1.0	-1.2	-1.3	-0.8	-1.9	-1.4	-1.3
Father’s age at death	1.0	1.4	8.5	2.9	-0.5	0.0	-0.7	0.4	-0.6	-1.3	-0.1	0.4	1.8	1.3	-0.2	1.2
Birth weight	1.0	2.2	6.2	-1.4	-1.1	-0.5	-0.8	1.3	-1.2	-1.0	-2.0	-2.5	-1.5	-1.8	-1.3	-1.7
Chest pain or discomfort	1.0	1.5	5.5	2.4	-1.9	-1.1	-2.0	0.4	-1.2	-1.6	-0.0	0.8	0.2	0.4	-0.2	0.3
Diastolic blood pressure, automated reading	1.0	3.1	10.4	-2.8	2.0	-0.5	2.1	0.4	2.1	3.2	2.0	-1.0	-1.2	0.8	1.2	-0.4
Pack years of smoking	1.0	1.4	2.8	1.2	-1.7	-1.4	-1.7	1.4	-1.5	-1.3	-0.4	-0.1	-1.0	-0.7	-1.1	-1.0
Hand grip strength (left)	0.9	2.2	6.0	-2.2	-0.0	0.9	0.1	1.2	-0.6	-0.1	-1.8	-2.4	-1.6	-2.2	-1.2	-1.8
Frequency of depressed mood in last 2 weeks	0.9	1.3	4.8	1.6	-1.1	-1.3	-1.3	2.2	-0.9	0.3	1.8	-0.2	-0.8	0.3	-0.1	-0.7
Medication: Metformin	0.9	1.2	4.7	-2.2	-0.6	-1.2	-0.2	-0.1	-0.3	0.5	-0.3	-1.1	-1.7	-1.3	-0.6	-1.6
Impedance of leg (right)	0.9	4.4	10.7	2.7	-3.0	-1.6	-2.9	-1.5	-3.0	-3.3	-2.4	-0.0	0.1	-0.5	-1.2	-0.7
Hand grip strength (right)	0.9	2.4	6.9	-2.4	0.5	0.9	0.5	2.6	-0.3	0.8	-0.7	-2.5	-1.7	-1.8	-0.8	-1.7
Impedance of leg (left)	0.9	4.5	12.8	3.1	-2.9	-1.0	-3.0	-1.3	-2.9	-3.6	-2.3	0.6	0.3	-0.5	-1.0	-0.4
Nervous feelings	0.9	1.7	4.9	2.2	-1.9	-1.6	-2.0	-0.2	-1.7	-1.6	-0.6	0.2	-0.5	0.3	-0.7	-0.7
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.9	1.3	-1.2	-0.4	-1.7	0.1	-1.5	-1.4	-0.4	0.4	-0.7	-1.0	-1.1	-0.6
Illnesses of siblings	0.9	1.3	5.1	2.1	-0.7	0.8	-0.5	-2.3	-0.4	-1.0	-0.7	1.0	1.4	0.8	-0.5	0.7
Medication: Paracetamol	0.9	1.5	3.5	-1.6	-0.8	-0.3	-0.9	0.8	-1.1	-0.4	-0.3	-1.9	-1.8	-1.5	-0.7	-1.7
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	4.2	-1.3	1.5	1.0	2.0	-0.4	1.7	1.9	1.2	1.2	0.7	0.4	1.2	1.2
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.5	0.7	-0.6	1.8	-0.9	-0.1	-0.6	-1.9	-1.8	0.7	0.8	-0.9	-0.7	0.5
Qualifications: nursing, teaching	0.9	1.3	2.7	1.2	0.8	0.8	0.9	-1.3	1.0	1.3	1.4	1.2	1.2	1.6	1.1	0.9
Hearing aid user	0.9	1.0	2.3	-0.1	-1.5	-1.5	-1.4	0.3	-1.4	-0.7	-0.1	-0.8	-1.0	-0.5	-1.1	-0.8
Prostate Cancer	0.8	1.1	4.9	2.2	-0.2	0.9	-0.3	-0.0	0.4	-0.9	-0.1	1.6	1.6	1.0	0.2	1.3
Heel T-Score	0.8	6.7	13.2	-2.9	3.2	3.6	3.0	-3.2	3.2	2.1	1.2	3.6	1.4	0.3	1.1	2.0
Sensitivity / hurt feelings	0.8	1.3	7.5	1.5	-0.3	-0.7	-0.1	2.7	0.2	1.0	1.8	0.4	-0.1	1.2	0.9	0.4
Vitamin and mineral supplements	0.8	1.1	3.4	-0.2	-1.1	-0.7	-1.1	0.3	-1.5	-0.8	-0.5	-1.8	-1.0	-1.1	-0.9	-1.5
Diabetes (mother)	0.8	1.0	4.6	-0.8	1.2	-0.3	1.4	0.2	0.9	2.1	1.6	0.8	-0.1	0.4	0.5	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.0	-0.1	-1.0	-1.5	-0.7	1.7	-1.2	-0.1	-0.1	-1.4	-1.0	-0.5	-0.3	-1.3
Angina (self-reported)	0.8	1.1	3.0	0.5	1.1	0.4	0.8	-0.5	0.6	1.0	1.6	1.4	0.7	1.1	1.7	1.0
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.0	-0.1	-1.1	-0.3	-1.2	0.4	-1.2	-0.5	-0.4	-1.7	-0.9	-1.0	-1.0	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.9	-1.0	1.1	1.2	1.7	0.4	1.1	1.6	0.6	-0.4	0.3	0.3	0.5	0.6
Mineral and other dietary supplements	0.8	1.1	2.5	0.7	-1.4	-1.5	-1.6	1.0	-0.8	-0.6	0.1	-0.2	-1.4	-0.3	-0.5	-1.5
Ever taken oral contraceptive pill	0.8	0.8	5.6	-1.3	0.5	-0.7	0.9	-2.4	0.4	1.1	0.8	0.3	0.0	0.1	0.3	0.0
Medication: Paracetamol	0.8	1.2	2.6	-1.4	-0.9	-0.3	-0.9	0.9	-1.1	-0.4	-0.2	-1.6	-1.6	-1.4	-0.7	-1.4
Bipolar Disorder or Schizophrenia	0.7	1.8	9.1	3.0	-0.0	0.2	-0.1	0.6	0.1	0.1	1.0	1.8	1.8	1.8	0.9	1.5
Intelligence (Savage-Jansen 2018)	0.7	2.1	6.7	-0.1	1.5	2.6	1.3	-0.3	2.0	0.6	0.9	2.2	1.3	0.4	1.9	1.2
Alzheimer’s Disease (in father)	0.7	0.7	1.9	-0.3	0.9	0.0	1.2	0.7	1.2	1.4	1.1	0.4	0.6	0.7	0.7	0.7
Alzheimer’s Disease (including proxy)	0.7	1.0	2.8	0.5	1.1	0.4	1.2	1.2	1.4	0.2	0.2	0.6	1.6	0.8	0.1	1.7
Irritable Bowel Disease (IBD)	0.7	1.7	7.1	-0.6	-0.5	0.2	-0.7	-0.3	-1.1	-2.4	-2.7	-0.4	-0.1	-1.6	-2.0	-0.3
HbA1C	0.7	0.7	4.4	1.5	-0.6	-0.9	-0.8	2.1	-0.5	-0.8	0.1	0.5	-0.0	0.1	-0.1	0.0
Blood White Count	0.7	4.9	8.1	-0.4	2.9	2.3	2.7	0.8	2.6	2.8	2.6	1.9	1.9	2.1	1.8	2.4
Multivitamins +/- minerals	0.7	0.9	2.0	0.9	0.9	0.4	1.1	0.0	1.1	0.9	0.7	0.7	1.1	1.3	0.7	1.4
Mouth/teeth dental problems	0.7	1.1	3.4	-1.8	0.9	-0.9	0.8	1.2	-0.0	1.0	-0.2	-1.7	-0.9	-0.8	-0.7	-0.8
Heart attack	0.7	0.8	5.4	2.3	-0.3	0.5	-0.5	-0.4	-0.4	0.0	1.3	0.3	0.8	1.0	0.4	0.9
Fluid intelligence score	0.7	1.4	3.7	-0.2	1.5	1.2	1.3	1.9	1.5	0.9	1.2	1.0	1.0	0.4	1.1	1.1
Falls in the last year	0.7	1.0	5.0	2.2	-1.0	-0.7	-1.4	-0.5	-0.6	-1.2	0.4	0.5	0.5	0.6	-1.0	0.5
Length of working week for main job	0.7	0.8	5.2	-2.3	0.7	0.6	0.2	-0.8	-0.2	-0.3	-0.6	-0.0	-0.7	-1.3	0.3	-0.7
Pulse wave reflection index	0.7	0.9	4.0	-0.3	1.3	2.0	1.6	0.4	1.1	0.4	-0.3	0.1	0.7	0.3	0.6	0.9
Mouth/teeth dental problems: Bleeding gums	0.7	0.8	2.7	1.0	-1.3	0.8	-1.0	-0.5	0.1	-1.6	-0.7	1.6	0.6	-0.3	-0.2	0.5
High blood pressure (siblings)	0.7	1.0	3.5	-1.9	0.4	-1.0	0.5	1.6	0.5	0.9	0.3	-1.3	-1.4	-0.7	0.1	-0.9
Age at first live birth	0.7	1.2	4.2	2.0	-0.6	1.8	-0.5	2.0	-0.0	-0.8	-0.3	0.7	1.2	0.3	0.1	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.8	0.6	-0.1	-1.1	-0.2	1.0	0.8	1.4	1.9	0.4	-0.7	1.0	0.1	-0.1
Medication: Aspirin	0.7	1.0	7.3	0.8	-1.2	-2.7	-1.0	-0.1	-0.5	0.1	0.3	-0.3	-1.1	0.3	-0.3	-0.5
Eye problems/disorders: Glaucoma	0.7	0.8	2.8	0.0	0.9	0.3	0.8	0.8	0.5	1.7	1.7	-0.1	0.3	0.4	1.5	0.3
Medication: Lisinopril	0.7	0.9	3.6	1.5	-1.0	-1.1	-0.7	1.7	-0.3	-0.3	0.4	-1.9	-0.2	0.4	0.5	0.0
Medication: Atorvastatin	0.7	0.9	1.4	0.5	1.1	1.2	0.9	0.2	0.8	0.9	1.2	1.1	0.6	1.1	1.1	0.8
Ulcerative Colitis (UC)	0.6	1.1	3.2	-0.8	1.2	1.6	0.9	-0.9	0.6	-1.2	-1.8	0.7	1.1	-0.6	-0.5	0.9
Ulcerative Colitis	0.6	0.8	1.7	-0.9	1.3	1.1	1.3	-0.2	1.0	-0.4	-0.9	1.3	0.8	-0.3	0.2	0.8
Blood Eosinophil Count	0.6	4.3	9.2	-0.4	2.7	1.4	2.6	-1.1	3.0	2.5	2.3	1.6	1.9	1.9	1.6	2.4
Severe depression (siblings)	0.6	0.6	4.5	-1.2	-0.2	-2.1	-0.4	-0.2	-0.2	0.1	0.3	-0.1	-0.9	-0.5	-0.3	-0.6
Pack years adult smoking proportion	0.6	0.9	1.9	0.7	-1.4	-1.2	-1.3	1.1	-1.2	-0.9	-0.1	0.1	-1.1	-0.5	-0.6	-0.9
Age when periods started (menarche)	0.6	1.4	4.9	-1.0	-0.3	0.9	-0.4	-0.8	-0.5	-1.9	-2.2	-1.0	0.3	-1.5	-2.0	-0.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	2.2	-1.3	1.3	1.1	0.9	-1.5	0.5	0.6	0.1	0.6	0.4	-0.5	0.8	0.0
Medication: Simvastatin	0.6	0.8	2.5	-1.5	0.1	0.5	-0.3	0.8	-0.1	0.5	0.3	-0.8	-1.6	-1.1	-1.2	-1.1
Neuroticism score	0.6	1.2	4.7	1.0	-1.4	-2.0	-1.2	2.2	-0.6	-0.1	0.6	0.0	-1.2	0.6	-0.2	-0.6
Time employed in main current job	0.6	0.7	4.9	0.2	-1.1	-0.0	-0.8	-2.2	-0.6	-0.9	-0.4	0.4	0.2	0.0	0.1	0.1
Exposure to tobacco smoke at home	0.6	0.7	2.4	0.9	0.6	0.1	0.5	1.5	0.8	0.9	1.3	-0.0	0.5	1.1	0.6	0.9
Hair/balding pattern: Pattern 4	0.6	1.5	2.9	-1.5	-1.1	-0.7	-1.0	-0.3	-0.8	-1.7	-1.7	-0.3	-1.3	-1.7	-1.2	-1.3
Glaucoma (self-reported)	0.6	0.7	2.0	1.0	0.9	0.4	0.6	0.3	0.3	1.3	1.4	0.1	0.5	0.8	1.3	0.6
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.5	-1.9	1.0	-0.7	1.0	-0.5	0.4	1.7	1.1	-0.1	-0.5	-0.1	0.3	-0.1
Number of full brothers	0.6	0.8	2.7	-0.8	-0.0	-1.6	-0.3	-1.1	-0.7	0.3	0.2	-0.9	-1.4	-0.1	0.7	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.8	0.6	0.1	-0.5	0.2	2.2	-0.2	1.2	1.5	0.1	-0.3	0.9	-0.3	0.3
Qualifications: College or University degree	0.6	2.0	15.6	0.7	1.2	4.0	0.9	-0.4	0.4	0.3	0.4	1.7	1.6	0.4	0.5	1.0
Supplements: Vitamin C	0.6	0.7	3.4	-0.8	-0.7	-0.3	-0.7	-1.8	0.2	-0.9	-0.9	1.1	-0.7	-0.6	-0.2	-0.2
Illnesses of father: None of the above (group 1)	0.6	0.7	2.2	1.0	-0.5	0.6	-0.7	-1.2	-0.6	-1.5	-0.6	1.2	1.0	-0.1	0.4	0.4
High cholesterol (Self-reported)	0.6	1.1	3.9	-1.2	-0.2	-0.3	-0.8	0.5	-0.7	-0.0	0.1	-0.6	-2.0	-1.4	-1.6	-1.7
Risk taking	0.6	0.9	2.7	0.9	-0.6	1.0	-1.3	0.7	-0.3	-1.6	-0.9	1.5	-0.3	-0.6	-1.1	0.1
Unable to work because of sickness or disability	0.6	0.8	3.0	1.7	-0.6	-0.6	-0.4	-1.6	0.1	-0.1	0.8	0.8	0.8	1.4	0.2	0.6
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.5	-0.8	1.2	1.0	1.1	0.5	1.6	1.0	1.3	1.3	0.3	0.0	1.6	0.4
Bipolar Disorder (2011)	0.5	0.5	2.4	0.4	-0.4	-1.5	-0.1	0.8	-0.5	0.8	0.7	-0.9	-0.4	0.5	-0.1	-0.5
Waist Hip Ratio (WHR)	0.5	2.1	6.2	1.8	-1.5	0.2	-2.0	-2.2	-1.2	-2.5	-1.0	1.9	0.3	-0.2	-0.6	0.4
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.6	-1.7	1.1	0.0	1.3	0.4	1.2	1.9	1.0	-0.2	-0.7	0.0	0.8	-0.1
Qualifications: CSEs or equivalent	0.5	0.6	2.4	0.1	-0.3	-0.8	0.2	-1.5	0.3	1.2	1.2	-0.0	-0.3	0.9	1.1	0.0
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.5	0.1	-0.7	-0.2	-1.0	-0.6	-1.6	-1.2	-1.5	-1.0	-0.9	-1.2	-1.2	-1.2
Diabetes (self-reported)	0.5	0.8	3.6	-1.9	0.5	-0.5	0.7	1.0	0.6	1.1	-0.1	-0.7	-1.4	-0.8	-0.1	-0.9
Alcohol intake versus 10 years previously	0.5	0.8	3.0	0.5	-1.0	-1.7	-1.2	0.5	-0.6	-1.0	-0.1	0.1	-1.0	-0.3	-0.9	-0.7
Number of live births	0.5	0.7	3.3	-0.8	0.4	-1.3	0.5	0.3	-0.7	1.1	0.7	-1.8	0.0	0.4	0.5	-0.4
Pulse rate	0.5	0.9	3.7	1.2	0.1	-0.9	-0.2	-1.9	0.2	0.5	1.4	0.9	0.3	1.2	0.9	0.3
Pulse wave Arterial Stiffness index	0.5	0.6	1.6	-0.7	0.9	0.5	1.1	-0.4	0.8	1.0	0.7	-1.3	-0.1	0.3	1.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	6.9	-0.6	-0.3	0.0	-0.2	2.6	-0.3	-0.1	-0.5	-0.9	-0.6	-0.8	-0.4	-0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.0	0.8	-1.4	-1.1	-1.2	-0.1	-1.2	-1.4	-1.1	-0.4	-0.0	-0.1	-0.3	-0.5
Pulse wave peak to peak time	0.5	0.6	1.3	0.4	-0.8	-0.4	-1.0	0.5	-0.8	-1.1	-0.9	1.1	0.0	-0.5	-1.1	-0.3
Medication: Seretide 50 evohaler	0.5	0.6	2.9	-0.4	0.1	-0.9	0.1	1.7	0.0	0.9	1.1	-1.0	-0.5	0.2	-0.0	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.6	-0.4	1.1	-0.4	1.3	0.2	1.2	1.0	0.6	0.1	0.4	0.8	0.7	0.6
Comparative height size at age 10	0.5	2.6	8.4	0.2	2.0	0.0	2.3	0.4	1.8	2.9	2.2	-0.1	1.0	1.7	1.7	1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.7	-0.2	1.3	0.8	1.3	-0.0	1.0	1.0	0.1	-0.6	0.5	0.8	0.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	6.2	-2.5	0.7	0.1	1.1	-0.7	0.4	1.2	0.2	-0.8	-0.7	-1.0	-0.4	-0.9
Average weekly red wine intake	0.5	0.8	2.0	-0.8	-0.7	0.1	-0.9	-0.8	-1.3	-0.8	-0.5	-0.2	-0.8	-1.2	-1.4	-0.7
Mood swings	0.5	0.9	4.6	0.5	-1.3	-2.2	-0.9	1.5	-0.2	-0.2	0.0	0.5	-0.9	0.4	-0.6	-0.5
Diabetes diagnosed by doctor	0.5	0.9	2.6	-1.3	1.3	0.4	1.4	0.6	1.4	1.6	0.7	0.3	-0.3	0.1	0.9	0.1
Commuting to job workplace: Walk	0.5	0.5	1.3	0.6	1.0	0.0	1.0	-0.5	1.1	0.4	0.2	0.5	0.7	1.0	0.7	0.8
Breast cancer (self-reported)	0.5	0.5	2.1	0.1	-0.8	-0.5	-0.7	1.2	-0.5	-0.4	-0.2	-0.2	-0.6	-0.8	-1.4	-0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.9	0.3	0.2	1.7	0.2	1.4	-0.1	-0.4	-1.0	-0.3	0.6	-0.4	-0.9	0.2
Medication: Blood pressure	0.5	1.0	2.8	0.4	-1.1	-1.2	-1.7	-1.1	-1.1	-1.2	-0.3	-0.6	-1.1	-0.4	-0.7	-0.9
Irritability	0.5	0.9	3.5	-1.4	-1.0	-1.1	-0.2	0.6	0.1	0.8	-0.3	-1.2	-1.9	-0.2	-0.6	-1.2
Bipolar Disorder (2018)	0.4	0.6	1.4	0.2	0.4	-0.7	0.5	0.5	0.4	1.2	1.1	1.1	0.4	1.0	0.8	0.3
Major Depression (MDD)	0.4	0.5	2.0	1.3	0.3	0.9	0.1	0.2	0.6	0.2	0.7	1.4	0.4	0.6	0.6	0.5
Ovarian Cancer	0.4	0.5	1.3	-0.5	0.8	0.5	1.0	-0.3	1.2	0.3	-0.1	1.1	0.7	0.2	0.2	0.9
Fasting Glucose	0.4	0.5	1.8	-1.4	0.7	0.4	0.8	0.4	0.5	-0.2	-1.3	-0.3	-0.7	-0.8	-0.5	-0.5
Number of treatments/medications taken	0.4	0.8	2.5	-1.6	0.8	-0.5	0.7	1.0	0.4	1.3	0.6	-1.0	-1.2	-0.6	-0.4	-0.5
Relative age of first facial hair	0.4	0.9	4.2	-1.3	-0.0	-1.2	0.1	2.0	0.4	0.8	0.4	0.5	-1.3	-0.6	0.2	-0.9
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.4	-0.6	-0.6	1.2	-0.4	0.3	-0.5	-0.8	-0.9	0.2	-0.2	-1.2	-0.6	-0.4
Systolic blood pressure, automated reading	0.4	1.1	3.6	-1.9	-0.2	-1.4	-0.3	0.3	-0.5	0.6	0.1	-1.5	-1.8	-1.0	-0.7	-1.4
Maternal smoking around birth	0.4	0.6	1.6	-1.2	-0.4	-0.3	-0.4	-0.0	0.3	-0.9	-1.0	-0.2	-1.0	-1.1	-1.3	-0.7
Taking other prescription medications	0.4	0.6	2.8	-1.7	0.7	0.1	0.7	1.3	0.6	0.7	-0.3	0.3	-0.6	-0.7	-0.8	-0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.3	-0.5	1.0	0.8	1.1	-0.5	0.4	0.3	0.0	0.2	0.9	0.0	1.0	0.4
Supplements: Glucosamine	0.4	0.5	2.8	-1.7	1.1	0.4	1.0	0.2	0.5	0.6	-0.1	-0.1	0.3	-0.4	-0.0	0.4
Medication: Levothyroxine sodium	0.4	0.7	3.0	-1.7	0.7	-0.1	1.0	0.2	1.0	1.3	0.9	1.1	-0.5	-0.2	0.1	0.2
Qualifications: None of the above	0.4	0.8	2.7	0.2	0.2	-1.6	0.5	-1.3	0.8	0.7	1.0	1.1	0.4	0.8	1.1	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.3	-0.3	-1.1	-0.8	-1.0	0.4	-1.1	-0.5	-0.1	-0.1	-0.4	-0.9	0.0	-0.7
Asthma	0.4	0.8	6.4	-1.1	0.7	0.7	0.8	2.5	0.7	1.0	0.3	0.1	-0.2	-0.1	-0.1	0.2
Medication: Cholesterol lowering	0.4	0.7	2.5	-0.9	1.2	0.7	1.0	0.3	0.8	1.6	1.2	0.5	-0.3	-0.0	-0.2	0.0
Depression (self-reported)	0.4	0.5	1.7	0.3	1.0	-0.1	0.7	0.5	0.5	1.2	1.3	0.8	-0.1	0.8	0.3	0.2
Peak expiratory flow (PEF)	0.4	0.9	3.0	-1.3	0.8	1.7	0.7	0.4	0.6	0.1	-1.1	-1.4	-0.5	-1.1	-0.4	-0.7
Family relationship satisfaction	0.4	0.5	4.8	0.6	-0.2	0.4	0.1	2.2	0.5	0.4	0.3	0.4	-0.2	0.4	-0.1	0.0
Loneliness, isolation	0.4	0.5	2.1	0.8	-1.1	-1.5	-0.9	0.3	0.1	-0.4	0.4	1.1	-0.4	0.4	-0.2	-0.1
Long-standing illness, disability or infirmity	0.4	0.6	1.9	-1.4	0.6	1.3	0.4	-0.6	-0.1	0.2	-0.4	-0.4	-0.3	-1.1	-1.0	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.8	0.5	0.7	1.2	0.7	-1.1	0.6	0.2	0.0	1.3	1.1	0.6	0.5	0.8
Medication for cholesterol	0.4	0.5	1.8	0.5	-0.4	0.9	0.2	-0.5	-0.0	-0.9	-1.4	0.9	1.2	-0.0	0.4	0.7
Asthma (self-reported)	0.4	0.8	6.5	-1.0	0.6	0.3	0.8	2.5	0.7	1.0	0.3	-0.3	-0.2	0.0	-0.2	0.2
Osteoarthritis (self-reported)	0.4	0.5	2.3	-0.2	-0.6	-1.5	-0.8	-0.2	-0.7	-0.4	-0.3	-0.6	-1.1	-0.3	-0.5	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	4.2	-0.0	-0.0	1.2	0.0	-2.0	0.5	0.4	0.9	1.2	0.3	0.3	1.2	0.3
Number of self-reported non-cancer illnesses	0.4	0.7	2.0	-1.3	1.0	-0.2	0.6	0.9	0.5	1.4	1.0	0.3	-1.0	-0.2	0.0	-0.4
Guilty feelings	0.4	0.6	2.6	1.6	-0.1	-1.2	-0.2	0.7	0.1	0.4	0.9	0.6	-0.0	1.1	0.7	0.3
Financial situation satisfaction	0.4	0.5	1.8	0.9	-0.8	-1.4	-0.9	-0.5	-0.7	-0.1	0.8	0.5	-0.7	0.0	0.5	-0.6
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.8	1.9	-0.5	0.4	-0.8	-0.4	-0.7	-0.3	0.9	-0.0	0.4	0.5	0.0	0.5
Triglycerides	0.3	0.5	2.2	-0.2	0.6	0.9	0.6	-1.4	0.4	0.3	0.4	1.5	0.7	-0.1	0.2	0.7
Blood Red Count	0.3	3.0	7.4	-0.1	-2.1	-2.7	-2.2	0.4	-2.4	-1.2	-0.7	-1.8	-1.7	-1.1	-1.6	-1.9
Systolic Blood Pressure	0.3	1.5	3.8	-0.9	-1.0	-1.6	-0.9	1.0	-1.2	-0.1	-0.8	-1.8	-1.9	-1.0	-0.9	-1.8
Cardiovascular Disease	0.3	1.1	4.9	-2.2	1.0	0.6	0.3	-0.3	0.7	0.9	0.9	-0.3	-1.9	-0.9	-0.3	-0.8
Hypothyroidism (self reported)	0.3	0.7	1.5	-1.1	0.9	1.0	1.2	-0.6	0.8	1.0	0.5	0.8	0.7	-0.2	0.7	0.9
Lung FEV1/FVC ratio	0.3	1.6	3.1	-0.4	-1.3	-1.0	-1.6	0.8	-1.6	-0.7	0.1	-1.8	-1.4	-0.9	-1.6	-1.6
Average weekly fortified wine intake	0.3	0.4	2.2	-0.3	-0.0	0.9	0.1	-0.1	-0.2	-0.5	-1.5	-0.2	0.2	-0.6	-1.1	-0.1
High blood pressure	0.3	0.8	3.7	-1.2	-0.2	-1.1	-1.0	-0.5	-0.2	-0.3	0.3	-0.4	-1.9	-0.9	-0.6	-1.2
Medication: Atenolol	0.3	0.3	0.9	-0.6	0.4	-0.9	0.1	-0.7	-0.2	1.0	0.8	-0.3	-0.2	0.2	0.6	-0.3
Chronic bronchitis/emphysema (father)	0.3	0.4	1.2	-0.0	-0.8	-0.8	-1.0	-0.2	-0.7	-0.6	-0.4	-0.3	-1.1	-0.1	-0.2	-0.8
Hair/balding pattern: Pattern 2	0.3	0.4	1.9	-0.4	-0.5	-0.7	-0.3	-0.0	0.1	0.7	0.3	-0.7	-1.4	0.3	0.1	-0.9
Pain all over the body in last month	0.3	0.4	1.6	0.1	-0.7	-1.2	-0.6	0.3	0.2	-0.1	0.4	0.9	-0.5	-0.3	-0.9	-0.4
Medication: Ramipril	0.3	0.4	2.5	-0.5	0.4	1.6	0.4	-0.5	0.5	0.1	-0.1	0.9	0.4	-0.3	-0.3	0.5
Noisy workplace	0.3	0.4	1.1	0.8	-0.7	-0.3	-0.7	-1.1	-0.7	-0.2	0.8	-0.0	-0.4	0.6	0.8	-0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.5	0.6	0.1	2.1	-0.3	1.0	-0.2	-1.1	-0.7	0.9	0.5	-0.6	-0.7	0.0
Mouth/teeth dental problems: Dentures	0.3	0.4	3.1	1.8	-0.3	-0.0	-0.4	0.1	-0.3	-0.2	0.7	0.1	0.4	0.9	0.8	0.3
Lung cancer (father)	0.3	0.4	2.3	-1.2	0.1	0.0	0.2	-1.5	0.5	0.4	0.0	0.6	-0.3	-0.2	-0.6	-0.2
Breastfed as a baby	0.3	0.3	1.0	0.8	-0.4	0.1	-0.4	1.0	-0.3	-0.7	-0.6	-0.4	0.5	-0.2	-0.9	0.5
Exposure to tobacco smoke outside home	0.3	0.4	1.7	1.3	-0.7	-0.8	-0.6	0.2	0.3	-0.5	0.4	0.5	0.2	0.4	0.1	0.6
Shortness of breath walking on level ground	0.3	0.4	2.5	0.2	0.2	-0.9	-0.1	0.3	0.2	0.8	1.6	-0.3	-0.7	0.3	0.1	-0.4
Medication: Ibuprofen	0.3	0.4	1.5	0.7	0.1	-0.4	0.3	1.2	-0.2	0.6	0.6	-0.8	0.3	0.6	0.7	0.1
Osteoporosis (self-reported)	0.3	0.4	1.8	-1.0	-0.4	-0.5	-0.3	0.5	-0.8	-0.3	-0.3	-1.4	-0.3	-0.9	-0.4	-0.4
Illnesses of father: High blood pressure	0.3	0.4	1.3	-1.1	0.0	-0.2	0.3	0.0	0.1	1.2	0.5	-0.8	-0.8	0.3	0.0	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.1	0.6	-0.1	1.4	-0.1	1.1	-0.2	0.1	0.2	-0.5	0.4	0.1	-0.2	0.1
Ever depressed for a whole week	0.3	0.4	1.9	1.4	-0.0	1.2	-0.1	-0.0	-0.2	-0.3	0.1	0.9	0.7	0.1	-0.2	0.7
Cholesterol lowering medication	0.3	0.5	1.7	-0.8	-0.4	-0.0	-0.6	-0.4	-0.5	-0.0	-0.1	-1.0	-1.3	-0.6	-0.8	-1.0
Breast Cancer	0.2	0.6	2.3	-0.8	0.8	-0.4	0.6	-1.2	0.3	0.5	0.7	-1.5	0.0	0.4	0.9	0.0
Coronary Artery Disease (CAD)	0.2	0.3	0.7	0.6	-0.4	-0.5	-0.1	-0.0	-0.2	-0.7	-0.7	-0.8	0.1	-0.3	-0.8	-0.4
LDL Cholesterol	0.2	0.3	1.4	1.2	-0.1	-0.1	0.1	0.4	0.3	0.1	0.3	0.8	0.3	0.7	0.7	0.4
Rheumatoid Arthritis	0.2	0.3	1.0	-0.6	-0.1	0.4	-0.5	-0.1	-0.4	-1.0	-0.5	-0.0	-0.3	-0.9	-0.7	-0.3
Respiratory disease	0.2	0.5	2.1	-1.5	0.4	0.3	0.5	0.9	0.2	1.1	0.4	-0.0	-0.7	-0.3	0.2	-0.4
Lung FVC	0.2	1.0	2.4	-1.2	-0.7	0.2	-0.8	0.9	-0.5	-0.9	-1.5	0.1	-1.4	-1.6	-0.8	-1.2
Serious illness, injury or assault to yourself	0.2	0.2	1.7	-0.2	-0.1	0.8	-0.2	1.3	-0.2	-0.2	-0.0	0.0	-0.2	-0.7	-0.1	-0.3
Forced vital capacity (FVC)	0.2	0.7	3.2	-1.5	0.7	1.8	0.6	0.5	0.8	0.2	-0.9	-0.1	-0.6	-0.8	-0.0	-0.4
Financial difficulties in last 2 years	0.2	0.3	1.0	-0.2	-0.5	-1.0	-0.4	1.0	0.0	0.2	0.6	0.5	-0.8	-0.2	0.0	-0.4
Allergy	0.2	0.4	1.4	-0.1	0.1	-0.5	0.4	-0.5	0.7	0.8	1.2	-0.1	0.2	0.7	0.8	0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.5	-1.5	0.4	1.6	0.3	0.1	0.4	0.1	-0.7	-0.6	-0.8	-1.1	-0.0	-0.7
Medication: Lansoprazole	0.2	0.3	0.9	0.4	0.5	0.7	0.3	1.0	0.5	0.3	0.6	0.4	0.1	0.4	-0.4	0.3
Birth weight of first child	0.2	0.3	0.8	0.1	0.2	-0.8	0.8	-0.8	0.5	0.5	-0.1	0.2	0.9	0.6	0.2	0.9
Blood clot in the leg (DVT)	0.2	0.3	0.7	0.8	-0.1	0.3	-0.0	-0.6	0.0	-0.2	-0.3	0.9	0.6	0.7	0.1	0.7
Health satisfaction	0.2	0.2	0.6	-0.0	-0.3	-0.0	-0.5	-0.4	-0.4	-0.1	0.3	0.1	-0.8	-0.5	-0.8	-0.6
Pulse rate, automated reading	0.2	0.7	2.8	-0.6	0.5	-1.0	0.1	-1.0	0.5	1.2	1.7	0.3	-0.9	0.7	0.3	-0.5
Alcohol intake frequency.	0.2	0.4	1.3	1.0	-0.8	-1.1	-0.8	-0.1	-0.7	-0.8	0.0	-0.4	0.1	0.1	0.2	0.1
Knee pain experienced in last month	0.2	0.4	1.3	-1.1	-0.2	-0.1	-0.0	-1.2	-0.4	0.2	-0.3	-0.4	-0.5	-0.8	-0.8	-0.6
Hypertension (Self-reported)	0.2	0.6	2.8	-0.9	-0.2	-0.9	-0.9	-0.3	-0.1	-0.2	0.4	-0.3	-1.7	-0.8	-0.4	-1.0
Miserableness	0.2	0.4	1.6	-0.4	0.1	-0.6	-0.2	1.2	0.2	0.4	1.0	0.0	-0.9	0.1	0.3	-0.5
Alcohol drinker status: Never	0.2	0.3	1.0	0.3	-0.1	-0.5	-0.6	-0.3	-0.7	-0.3	0.6	-1.0	-0.5	-0.2	0.5	-0.3
Average weekly beer plus cider intake	0.2	0.4	1.5	0.5	-0.6	-1.1	-0.3	-1.2	0.4	-0.1	0.2	0.4	-0.2	0.4	0.7	-0.1
Fractured/broken bones in last 5 years	0.2	0.3	0.8	-0.5	0.6	0.3	0.5	0.4	0.8	-0.1	-0.5	0.7	0.3	-0.4	-0.9	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.0	0.1	0.4	0.9	1.3	0.7	0.4	0.5	-0.6	0.1	1.4	0.4	0.4	0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.0	1.0	-0.1	0.2	-0.1	-0.5	-0.0	-0.2	-0.2	1.0	0.7	0.8	0.0	0.8
HDL Cholesterol	0.1	0.2	1.0	-0.7	-0.0	0.4	-0.1	-1.0	-0.3	-0.2	-0.5	-0.0	0.1	-0.4	-0.8	-0.1
Primary Biliary Cirrhosis	0.1	0.2	1.2	-0.4	0.6	-0.0	0.3	-1.1	0.4	0.4	0.3	0.5	-0.1	-0.0	0.4	0.0
Blood Platelet Count	0.1	1.7	2.6	1.0	1.6	1.3	1.6	-0.0	1.6	1.5	1.6	0.4	1.3	1.4	0.9	1.4
Height	0.1	2.8	12.7	-1.6	-0.2	0.3	-0.0	2.1	-0.7	-0.7	-2.0	-3.6	-1.2	-2.3	-1.8	-1.4
Hair Pigment	0.1	1.8	5.3	0.3	1.2	1.5	0.9	-1.9	1.5	-0.6	-0.5	2.3	1.8	0.2	-0.2	1.9
Tanning	0.1	0.8	3.2	1.4	-1.2	0.1	-0.9	-1.8	-0.4	-1.3	-0.6	0.2	0.3	0.2	0.0	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.8	0.1	-0.2	0.0	0.1	0.9	-0.1	-0.4	-0.8	-0.1	0.1	0.0	0.3	0.2
Sitting height	0.1	0.6	1.6	-1.2	0.5	1.3	0.7	0.2	-0.3	0.3	-0.8	-1.3	-0.1	-1.2	-0.5	-0.6
High blood pressure (mother)	0.1	0.1	0.6	-0.6	0.0	0.3	0.0	-0.6	-0.5	0.2	-0.0	-0.8	-0.3	0.0	-0.1	-0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.6	-0.5	-0.1	-0.6	-0.1	-0.1	-0.8	0.5	0.6	-0.4	0.1	0.1	-0.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.4	-1.0	0.3	1.6	0.3	-0.5	0.6	-0.0	-0.5	0.2	-0.4	-0.8	0.1	-0.3
Standing height	0.1	1.1	3.3	-1.2	0.7	1.3	0.8	1.5	0.0	0.0	-1.1	-1.8	-0.3	-1.2	-0.9	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.5	1.9	-1.4	0.2	1.4	0.3	-0.2	0.6	-0.1	-1.0	0.1	-0.7	-1.0	-0.2	-0.5
Medication: Blood pressure	0.1	0.2	0.7	-0.8	0.3	0.4	0.2	0.3	0.6	0.3	0.1	-0.8	-0.7	-0.5	-0.3	-0.3
Suffer from ‘nerves’	0.1	0.2	0.6	0.3	-0.6	-0.5	-0.6	-0.1	-0.6	-0.0	0.4	0.8	-0.5	0.4	0.4	-0.3

Hub : Genes

PTBP2

Models

Trait associations