Best TWAS P=6.17e-10 · Best GWAS P=7.72e-09 conditioned to 1.2e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | C12orf52 | 0.09 | 0.06 | enet | 26 | 0.05 | 1.3e-04 | 3.6 | -5.8 | 5.9e-09 | -0.06 | 0.78 | 0.03 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | C12orf52 | 0.17 | 0.00 | enet | 31 | 0.02 | 7.9e-02 | 3.6 | -6.2 | 6.2e-10 | -0.11 | 0.10 | 0.06 | TRUE |
| 3 | YFS | Blood | OAS3 | 0.05 | 0.04 | bslmm | 391 | 0.04 | 8.1e-13 | -4.2 | 5.2 | 2.3e-07 | 0.00 | 0.61 | 0.33 | TRUE |