[Hub]/) : Traits : BMI :

chr12:109,231,851-111,634,281

Best TWAS P=7.25e-11 · Best GWAS P=9.17e-11 conditioned to 0.00348

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MMAB 0.10 -0.01 lasso 4 0.00 3.8e-01 -5.3 -5.7 1.2e-08 0.01 0.07 0.42 TRUE
2 GTEx Artery Tibial VPS29 0.05 0.03 lasso 3 0.02 5.9e-03 6.5 6.1 1.4e-09 0.98 0.02 0.92 FALSE
3 GTEx Cells EBV-transformed lymphocytes ARPC3 0.13 0.09 lasso 4 0.04 2.0e-02 6.3 -6.3 2.6e-10 -0.65 0.02 0.84 FALSE
4 GTEx Cells Transformed fibroblasts VPS29 0.09 0.13 lasso 3 0.13 9.8e-10 6.5 6.1 1.1e-09 0.99 0.01 0.99 FALSE
5 GTEx Colon Sigmoid KCTD10 0.25 0.16 lasso 8 0.15 6.2e-06 4.9 -5.5 3.0e-08 -0.01 0.09 0.89 FALSE
6 GTEx Colon Transverse VPS29 0.13 0.01 enet 41 0.10 2.0e-05 4.7 5.4 7.0e-08 0.58 0.05 0.48 FALSE
7 GTEx Colon Transverse MMAB 0.08 0.07 lasso 2 0.05 1.7e-03 4.9 -5.1 2.9e-07 -0.02 0.11 0.74 FALSE
8 GTEx Esophagus Mucosa VPS29 0.14 0.13 lasso 6 0.13 3.0e-09 4.9 5.5 2.9e-08 0.94 0.05 0.95 FALSE
9 GTEx Esophagus Muscularis IFT81 0.26 0.24 lasso 5 0.26 6.7e-16 4.7 5.3 9.2e-08 0.65 0.02 0.98 FALSE
10 GTEx Lung GPN3 0.08 0.08 enet 8 0.07 1.0e-05 4.8 -5.2 1.9e-07 -0.83 0.37 0.62 FALSE
11 GTEx Muscle Skeletal ARPC3 0.14 0.11 enet 23 0.10 2.2e-10 6.0 -6.3 3.8e-10 -0.75 0.03 0.97 FALSE
12 GTEx Muscle Skeletal VPS29 0.06 0.06 lasso 3 0.05 4.3e-06 6.5 6.2 6.9e-10 0.99 0.01 0.99 FALSE
13 GTEx Muscle Skeletal IFT81 0.08 0.08 lasso 5 0.07 1.7e-07 6.3 6.5 7.2e-11 0.67 0.02 0.98 TRUE
14 GTEx Muscle Skeletal ANAPC7 0.08 0.01 lasso 3 0.00 1.1e-01 4.8 6.0 2.4e-09 0.90 0.03 0.77 FALSE
15 GTEx Nerve Tibial VPS29 0.05 0.01 lasso 4 0.00 2.5e-01 5.4 5.4 7.6e-08 0.91 0.05 0.57 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic VPS29 0.06 0.01 lasso 3 0.01 6.9e-02 6.3 6.5 8.8e-11 0.87 0.03 0.72 FALSE
17 GTEx Skin Sun Exposed Lower leg ARPC3 0.13 0.15 lasso 3 0.15 1.9e-12 6.1 -6.1 9.2e-10 -0.69 0.05 0.95 FALSE
18 GTEx Spleen VPS29 0.24 0.01 enet 14 0.04 2.9e-02 4.7 5.7 1.3e-08 0.75 0.03 0.67 FALSE
19 GTEx Testis ARPC3 0.16 0.16 lasso 3 0.14 7.5e-07 6.1 -6.1 9.0e-10 -0.69 0.04 0.96 FALSE
20 GTEx Thyroid VPS29 0.07 0.01 lasso 5 0.01 8.9e-02 5.4 5.4 5.4e-08 0.90 0.02 0.78 FALSE
21 NTR Blood GPN3 0.03 0.01 blup 236 0.02 2.7e-06 4.8 -5.8 6.5e-09 -0.81 0.04 0.96 FALSE
22 YFS Blood ARPC3 0.06 0.04 lasso 4 0.05 7.9e-16 5.5 -5.7 1.3e-08 -0.87 0.56 0.44 FALSE
23 YFS Blood GLTP 0.05 0.01 enet 14 0.04 1.5e-13 4.7 5.8 6.0e-09 0.60 0.01 0.99 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma VPS29 0.02 0.02 lasso 5 0.03 4.6e-06 5.4 6.0 2.7e-09 0.94 0.02 0.97 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ARPC3 0.03 0.01 blup 22 0.02 3.6e-03 6.1 -5.2 1.8e-07 -0.67 0.00 0.87 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MYO1H 0.22 0.16 lasso 5 0.15 4.1e-16 -5.2 5.2 2.3e-07 -0.08 0.00 0.99 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma RAD9B 0.04 0.02 blup 29 0.03 4.9e-04 6.0 6.0 1.9e-09 0.74 0.01 0.90 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma VPS29 0.06 0.06 enet 7 0.06 2.1e-07 5.4 6.0 1.5e-09 0.94 0.09 0.91 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma RAD9B 0.04 0.03 lasso 5 0.01 7.0e-03 6.1 5.8 5.6e-09 0.61 0.02 0.98 FALSE
30 The Cancer Genome Atlas Prostate Adenocarcinoma KCTD10 0.30 0.20 enet 12 0.22 3.1e-22 -5.2 -5.4 6.4e-08 0.05 0.01 0.99 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma C12orf24 0.08 0.08 lasso 3 0.10 1.6e-09 5.5 -5.2 2.6e-07 -0.89 0.19 0.80 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma RAD9B 0.10 0.06 enet 5 0.06 1.2e-06 6.1 6.1 9.5e-10 0.69 0.02 0.98 FALSE