Best TWAS P=3.69e-08 · Best GWAS P=1.61e-20 conditioned to 1.68e-19
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | RNF219 | 0.08 | 0.02 | enet | 16 | 0.02 | 7.2e-03 | 4.2 | -5.5 | 3.7e-08 | 0.05 | 0.26 | 0.03 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | RNF219-AS1 | 0.15 | 0.11 | bslmm | 766 | 0.11 | 1.7e-13 | 4.3 | 5.1 | 3.0e-07 | -0.05 | 1.00 | 0.00 | FALSE |