Best TWAS P=2.74e-09 · Best GWAS P=3.16e-06 conditioned to 0.00711
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | RP11-958N24.1 | 0.22 | 0.02 | lasso | 5 | 0.06 | 4.8e-03 | -4.3 | 5.7 | 1.2e-08 | -0.61 | 0.00 | 0.16 | FALSE |
2 | GTEx | Cells EBV-transformed lymphocytes | PKD1P6 | 0.14 | 0.00 | lasso | 5 | 0.00 | 2.7e-01 | 3.4 | 6.0 | 2.7e-09 | -0.36 | 0.00 | 0.03 | TRUE |
3 | NTR | Blood | PDXDC1 | 0.12 | 0.12 | enet | 26 | 0.15 | 1.3e-46 | -4.2 | 5.4 | 8.1e-08 | -0.79 | 0.02 | 0.87 | FALSE |