[Hub]/) : Traits : BMI : ← →

chr16:2,741,812-5,706,977

Best TWAS P=3.82e-24 · Best GWAS P=3.14e-32 conditioned to 1.45e-10

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NLRC3	0.44	0.40	lasso	3	0.40	9.3e-53	5.3	-5.2	2.1e-07	-0.04	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	TRAP1	0.43	0.30	enet	19	0.29	2.6e-24	-4.4	5.9	3.4e-09	0.02	1.00	0.00	FALSE
3	GTEx	Artery Aorta	CLUAP1	0.40	0.33	enet	18	0.33	5.4e-19	5.3	5.9	3.4e-09	0.08	1.00	0.00	FALSE
4	GTEx	Artery Aorta	UBN1	0.18	0.15	lasso	4	0.14	6.8e-08	6.7	-6.1	8.9e-10	-0.04	0.05	0.95	FALSE
5	GTEx	Artery Coronary	TRAP1	0.44	0.27	lasso	3	0.29	1.6e-10	-4.4	5.7	1.6e-08	0.08	0.88	0.01	FALSE
6	GTEx	Artery Tibial	UBN1	0.20	0.06	lasso	7	0.07	4.8e-06	6.3	-5.9	4.6e-09	-0.02	0.11	0.89	FALSE
7	GTEx	Artery Tibial	TRAP1	0.42	0.26	enet	27	0.32	1.3e-25	-4.4	5.1	2.8e-07	0.09	1.00	0.00	FALSE
8	GTEx	Artery Tibial	NLRC3	0.39	0.26	lasso	7	0.36	1.5e-29	5.3	-6.4	2.0e-10	-0.08	1.00	0.00	FALSE
9	GTEx	Brain Caudate basal ganglia	NLRC3	0.41	0.11	lasso	4	0.24	2.0e-07	5.3	-6.9	4.8e-12	-0.06	0.46	0.03	FALSE
10	GTEx	Brain Cerebellar Hemisphere	NLRC3	0.40	0.39	lasso	2	0.40	2.1e-11	5.3	-6.3	3.7e-10	-0.02	0.94	0.00	FALSE
11	GTEx	Brain Cerebellum	NLRC3	0.36	0.36	lasso	4	0.36	1.4e-11	5.3	-5.6	1.7e-08	-0.02	0.97	0.00	FALSE
12	GTEx	Brain Cerebellum	SLX4	0.33	0.14	lasso	3	0.10	6.8e-04	6.0	-6.3	3.4e-10	-0.01	0.16	0.05	FALSE
13	GTEx	Brain Cortex	NLRC3	0.30	0.34	lasso	1	0.31	2.3e-09	5.3	-5.3	1.3e-07	-0.03	0.88	0.01	FALSE
14	GTEx	Brain Frontal Cortex BA9	NLRC3	0.50	0.18	enet	30	0.33	1.6e-09	4.3	-7.6	2.9e-14	0.03	0.44	0.06	TRUE
15	GTEx	Brain Hippocampus	CLUAP1	0.37	0.10	lasso	5	0.09	4.9e-03	5.3	6.9	5.7e-12	0.02	0.17	0.06	FALSE
16	GTEx	Brain Hippocampus	NLRC3	0.49	0.28	lasso	5	0.34	8.0e-09	5.3	-6.4	1.4e-10	-0.07	0.18	0.05	FALSE
17	GTEx	Brain Hypothalamus	NLRC3	0.38	0.15	lasso	6	0.17	8.3e-05	5.3	-6.0	1.7e-09	-0.07	0.14	0.07	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	NLRC3	0.24	0.14	enet	6	0.22	1.1e-06	5.3	-6.0	2.1e-09	-0.05	0.37	0.03	FALSE
19	GTEx	Brain Putamen basal ganglia	ROGDI	0.41	0.38	lasso	7	0.30	7.9e-08	4.6	-5.2	1.9e-07	-0.06	0.07	0.91	FALSE
20	GTEx	Breast Mammary Tissue	CLUAP1	0.26	0.13	lasso	8	0.13	4.6e-07	5.3	5.7	1.2e-08	0.05	1.00	0.00	FALSE
21	GTEx	Breast Mammary Tissue	UBN1	0.21	0.05	enet	29	0.09	1.9e-05	4.2	-5.4	5.2e-08	-0.01	0.22	0.40	FALSE
22	GTEx	Colon Sigmoid	CLUAP1	0.47	0.32	lasso	9	0.34	1.1e-12	4.3	6.1	1.4e-09	0.04	1.00	0.00	FALSE
23	GTEx	Colon Transverse	CLUAP1	0.25	0.09	lasso	3	0.14	2.0e-07	5.3	5.6	2.3e-08	0.06	0.89	0.00	FALSE
24	GTEx	Esophagus Gastroesophageal Junction	CLUAP1	0.58	0.36	lasso	9	0.38	1.5e-14	5.3	5.3	1.4e-07	0.06	1.00	0.00	FALSE
25	GTEx	Esophagus Gastroesophageal Junction	NLRC3	0.29	0.16	lasso	3	0.18	5.1e-07	5.3	-6.4	1.6e-10	-0.05	0.81	0.01	FALSE
26	GTEx	Esophagus Mucosa	CLUAP1	0.30	0.18	lasso	7	0.19	1.3e-12	5.3	5.2	2.1e-07	0.06	1.00	0.00	FALSE
27	GTEx	Esophagus Mucosa	UBN1	0.12	0.06	lasso	3	0.08	5.1e-06	6.2	-6.8	1.4e-11	-0.05	0.09	0.90	TRUE
28	GTEx	Esophagus Muscularis	CLUAP1	0.42	0.42	lasso	2	0.44	4.8e-29	5.3	5.8	5.9e-09	0.03	1.00	0.00	FALSE
29	GTEx	Esophagus Muscularis	UBN1	0.18	0.19	lasso	4	0.19	9.1e-12	6.7	-6.7	2.8e-11	-0.04	0.05	0.95	FALSE
30	GTEx	Esophagus Muscularis	NLRC3	0.48	0.29	lasso	6	0.36	5.1e-23	5.3	-6.8	9.5e-12	-0.07	1.00	0.00	FALSE
31	GTEx	Heart Atrial Appendage	CLUAP1	0.40	0.16	enet	13	0.29	2.3e-13	4.3	6.1	1.2e-09	0.07	1.00	0.00	FALSE
32	GTEx	Heart Atrial Appendage	NLRC3	0.27	0.07	lasso	3	0.08	2.2e-04	5.3	-6.4	1.8e-10	-0.07	0.29	0.09	FALSE
33	GTEx	Heart Left Ventricle	CLUAP1	0.39	0.30	lasso	6	0.34	1.4e-18	5.3	5.7	1.2e-08	0.04	1.00	0.00	FALSE
34	GTEx	Lung	CLUAP1	0.16	0.10	enet	9	0.12	2.1e-09	5.3	5.9	3.0e-09	0.02	1.00	0.00	FALSE
35	GTEx	Lung	ZSCAN32	0.08	0.02	lasso	3	0.02	6.3e-03	6.0	6.0	2.3e-09	0.04	0.04	0.69	FALSE
36	GTEx	Muscle Skeletal	CLUAP1	0.21	0.19	lasso	6	0.20	3.8e-19	5.3	5.9	2.8e-09	0.02	1.00	0.00	FALSE
37	GTEx	Muscle Skeletal	TRAP1	0.32	0.06	enet	26	0.22	1.6e-21	-4.4	5.8	5.4e-09	0.04	1.00	0.00	FALSE
38	GTEx	Muscle Skeletal	NLRC3	0.16	0.11	lasso	2	0.11	7.9e-11	5.3	-5.4	8.0e-08	-0.03	1.00	0.00	FALSE
39	GTEx	Nerve Tibial	CLUAP1	0.53	0.27	lasso	7	0.42	9.9e-32	5.3	6.4	1.2e-10	0.01	1.00	0.00	FALSE
40	GTEx	Nerve Tibial	UBN1	0.14	0.12	lasso	4	0.11	5.6e-08	6.6	-6.7	1.8e-11	-0.04	0.07	0.93	FALSE
41	GTEx	Nerve Tibial	TRAP1	0.60	0.34	enet	49	0.39	5.6e-29	-4.4	5.6	2.3e-08	0.00	1.00	0.00	FALSE
42	GTEx	Nerve Tibial	NLRC3	0.29	0.24	lasso	3	0.32	8.7e-23	5.3	-6.4	1.7e-10	-0.06	1.00	0.00	FALSE
43	GTEx	Nerve Tibial	LA16c-306E5.3	0.19	0.12	lasso	2	0.10	2.5e-07	5.3	-5.4	7.6e-08	-0.03	0.98	0.00	FALSE
44	GTEx	Ovary	CLUAP1	0.29	0.14	lasso	3	0.11	1.4e-03	5.3	5.5	4.6e-08	0.03	0.14	0.05	FALSE
45	GTEx	Ovary	NLRC3	0.40	0.11	lasso	7	0.16	9.5e-05	6.7	-6.5	6.0e-11	-0.07	0.31	0.05	FALSE
46	GTEx	Pancreas	CLUAP1	0.28	0.21	lasso	3	0.24	2.3e-10	6.2	6.6	4.6e-11	0.03	0.99	0.00	FALSE
47	GTEx	Pancreas	TRAP1	0.36	0.09	lasso	6	0.13	2.9e-06	-4.4	5.2	2.3e-07	0.12	0.19	0.04	FALSE
48	GTEx	Pituitary	CLUAP1	0.32	0.26	lasso	3	0.17	5.6e-05	6.7	6.5	6.3e-11	0.02	0.18	0.05	FALSE
49	GTEx	Prostate	CLUAP1	0.44	0.36	lasso	3	0.35	1.1e-09	5.3	5.2	2.4e-07	0.04	0.73	0.02	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	UBN1	0.22	0.16	lasso	4	0.14	2.5e-08	6.3	-5.9	3.5e-09	-0.04	0.09	0.91	FALSE
51	GTEx	Skin Not Sun Exposed Suprapubic	NLRC3	0.29	0.16	lasso	6	0.16	6.2e-09	5.3	-5.5	4.0e-08	-0.04	0.99	0.00	FALSE
52	GTEx	Skin Sun Exposed Lower leg	CLUAP1	0.34	0.25	lasso	6	0.27	1.1e-22	6.0	6.5	8.6e-11	0.04	1.00	0.00	FALSE
53	GTEx	Skin Sun Exposed Lower leg	PPL	0.10	0.04	lasso	6	0.02	5.7e-03	6.2	6.2	4.4e-10	0.05	0.08	0.72	FALSE
54	GTEx	Skin Sun Exposed Lower leg	UBN1	0.16	0.15	lasso	5	0.17	9.5e-14	6.7	-6.5	7.6e-11	-0.05	0.06	0.94	FALSE
55	GTEx	Skin Sun Exposed Lower leg	NLRC3	0.16	0.17	lasso	3	0.18	1.7e-14	4.3	-5.1	3.1e-07	-0.05	1.00	0.00	FALSE
56	GTEx	Stomach	TRAP1	0.42	0.18	enet	28	0.20	3.9e-10	-4.4	5.3	1.0e-07	0.08	0.93	0.00	FALSE
57	GTEx	Testis	TRAP1	0.37	0.26	enet	20	0.25	1.2e-11	-4.4	5.4	6.1e-08	0.07	1.00	0.00	FALSE
58	GTEx	Thyroid	CLUAP1	0.37	0.17	lasso	6	0.27	1.1e-20	5.3	6.0	1.9e-09	0.03	1.00	0.00	FALSE
59	GTEx	Thyroid	LA16c-306E5.3	0.11	0.15	lasso	1	0.15	1.0e-11	5.3	-5.3	1.3e-07	-0.03	1.00	0.00	FALSE
60	GTEx	Uterus	NLRC3	0.50	0.28	lasso	4	0.29	8.8e-07	5.3	-5.4	7.9e-08	-0.06	0.20	0.05	FALSE
61	GTEx	Whole Blood	CLUAP1	0.07	0.02	lasso	3	0.01	6.5e-02	6.1	5.9	3.3e-09	0.03	0.17	0.03	FALSE
62	ROSMAP	Brain Pre-frontal Cortex	RP11-462G12.1	0.11	0.07	enet	18	0.06	1.1e-08	-11.2	-10.1	3.8e-24	0.86	0.00	1.00	TRUE
63	ROSMAP	Brain Pre-frontal Cortex	RP11-127I20.5	0.31	0.32	bslmm	374	0.40	2.0e-55	6.3	5.5	3.1e-08	0.03	0.36	0.64	FALSE
64	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	NLRC3	0.05	0.01	blup	39	0.02	9.8e-03	6.2	-6.9	6.3e-12	-0.09	0.02	0.68	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLUAP1	0.03	0.02	enet	5	0.02	3.3e-05	5.6	5.2	2.2e-07	0.07	0.10	0.64	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	NLRC3	0.09	0.07	lasso	5	0.10	2.9e-19	5.3	-6.5	1.0e-10	-0.07	0.65	0.35	FALSE
67	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	NLRC3	0.07	0.02	blup	39	0.01	7.4e-02	-5.2	-6.9	4.0e-12	-0.12	0.02	0.76	FALSE
68	The Cancer Genome Atlas	Colon Adenocarcinoma	BTBD12	0.05	0.01	blup	41	0.02	1.5e-02	-5.6	5.5	4.1e-08	0.14	0.02	0.20	FALSE
69	The Cancer Genome Atlas	Colon Adenocarcinoma	NLRC3	0.14	0.04	blup	39	0.10	1.9e-06	5.0	-6.4	1.5e-10	-0.09	0.03	0.89	FALSE
70	The Cancer Genome Atlas	Colon Adenocarcinoma	UBN1	0.05	0.04	enet	7	0.05	4.2e-04	-6.4	5.6	1.8e-08	0.06	0.02	0.76	FALSE
71	The Cancer Genome Atlas	Glioblastoma Multiforme	NLRC3	0.32	0.11	lasso	5	0.21	4.3e-07	5.3	-6.1	1.1e-09	-0.08	0.07	0.54	FALSE
72	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NLRC3	0.04	0.02	lasso	3	0.03	2.1e-04	-4.0	-6.1	9.0e-10	-0.15	0.07	0.44	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NLRC3	0.13	0.12	blup	39	0.13	4.9e-14	5.3	-5.5	4.0e-08	-0.05	0.03	0.97	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ROGDI	0.03	0.04	lasso	3	0.03	1.6e-04	6.3	-6.3	3.3e-10	0.01	0.02	0.95	FALSE
75	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBN1	0.07	0.01	enet	13	0.04	2.7e-05	4.4	-6.0	1.6e-09	0.05	0.07	0.27	FALSE
76	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	NLRC3	0.35	0.08	lasso	6	0.17	4.4e-10	-4.0	-5.9	3.2e-09	-0.11	0.10	0.90	FALSE
77	The Cancer Genome Atlas	Brain Lower Grade Glioma	NLRC3	0.32	0.28	enet	17	0.35	8.2e-41	5.3	-6.8	1.5e-11	-0.10	0.81	0.19	FALSE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	ROGDI	0.05	0.02	lasso	2	0.03	6.0e-04	-3.9	-5.7	9.8e-09	-0.05	0.05	0.10	FALSE
79	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	NLRC3	0.10	0.04	lasso	2	0.04	6.2e-03	5.3	-6.0	1.5e-09	-0.02	0.01	0.81	FALSE
80	The Cancer Genome Atlas	Lung Adenocarcinoma	NLRC3	0.09	0.08	enet	3	0.08	3.5e-09	5.3	-5.3	9.0e-08	-0.03	0.80	0.20	FALSE
81	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NLRC3	0.03	0.01	lasso	3	0.00	3.3e-01	6.0	-5.9	3.7e-09	-0.02	0.01	0.62	FALSE
82	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	NLRC3	0.15	0.05	lasso	2	0.11	1.1e-07	5.3	-6.2	7.5e-10	-0.07	0.21	0.35	FALSE
83	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NLRC3	0.14	0.11	enet	7	0.14	2.5e-06	5.3	-5.5	3.0e-08	-0.05	0.09	0.68	FALSE
84	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NLRC3	0.36	0.20	enet	18	0.25	2.9e-10	5.3	-5.3	1.2e-07	-0.07	0.08	0.92	FALSE
85	The Cancer Genome Atlas	Prostate Adenocarcinoma	NLRC3	0.42	0.25	lasso	6	0.36	1.2e-38	5.3	-6.5	7.3e-11	-0.07	0.61	0.39	FALSE
86	The Cancer Genome Atlas	Rectum Adenocarcinoma	NLRC3	0.32	0.08	enet	10	0.23	3.3e-06	5.3	-6.4	1.9e-10	-0.14	0.03	0.48	FALSE
87	The Cancer Genome Atlas	Soft Tissue Sarcoma	NLRC3	0.13	0.09	lasso	1	0.09	8.2e-06	5.3	-5.3	1.3e-07	-0.03	0.60	0.32	FALSE
88	The Cancer Genome Atlas	Thyroid Carcinoma	NLRC3	0.31	0.21	lasso	3	0.26	8.4e-26	5.3	-6.0	1.9e-09	-0.07	0.83	0.17	FALSE
89	The Cancer Genome Atlas	Thyroid Carcinoma	TRAP1	0.08	0.02	lasso	4	0.03	2.7e-04	-6.4	5.5	3.2e-08	0.18	0.00	0.99	FALSE
90	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NLRC3	0.33	0.00	blup	40	0.02	9.3e-02	5.3	-6.3	3.4e-10	-0.14	0.02	0.31	FALSE