Best TWAS P=1.64e-07 · Best GWAS P=2.47e-07 conditioned to 0.105
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | CYB5A | 0.43 | 0.17 | lasso | 9 | 0.19 | 1.3e-05 | -5.0 | -5.2 | 1.6e-07 | 0.80 | 0.03 | 0.94 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CYB5A | 0.03 | 0.01 | blup | 85 | 0.01 | 7.2e-03 | -4.7 | 5.2 | 2.5e-07 | -0.83 | 0.02 | 0.87 | FALSE |