TWAS hub - CYB5A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1720	0.0670	5.8e-03	0.010	NA	0.002	NA	0.000	8.2e-02	NA	2.3e-01	NA	3.1e-01
2	GTEx	Artery Tibial	0.1925	0.0459	4.8e-07	0.144	NA	0.084	NA	0.106	2.4e-11	NA	3.8e-07	NA	1.2e-08
3	GTEx	Brain Cerebellar Hemisphere	0.3150	0.0920	9.6e-04	0.268	NA	0.192	NA	0.210	1.4e-07	NA	1.1e-05	NA	4.2e-06
4	GTEx	Brain Cerebellum	0.4420	0.0880	1.1e-06	0.142	NA	0.202	NA	0.177	5.5e-05	NA	1.3e-06	NA	6.2e-06
5	GTEx	Brain Nucleus accumbens basal ganglia	0.3000	0.1120	9.8e-03	0.001	NA	-0.009	NA	0.029	3.0e-01	NA	6.7e-01	NA	5.7e-02
6	GTEx	Cells Transformed fibroblasts	0.2130	0.0540	6.0e-07	0.075	NA	0.089	NA	0.106	2.9e-06	NA	3.3e-07	NA	2.3e-08
7	GTEx	Spleen	0.4310	0.0980	5.9e-05	0.173	NA	0.116	NA	0.190	3.3e-05	NA	6.9e-04	NA	1.3e-05
8	YFS	Blood	0.0680	0.0148	9.6e-11	0.038	0.037	0.063	0.051	0.055	1.8e-12	2.6e-12	9.1e-20	2.7e-16	2.3e-17
9	TCGA	Glioblastoma Multiforme	0.1670	0.0920	1.1e-03	0.136	0.124	0.130	NA	0.117	6.2e-05	1.4e-04	9.2e-05	NA	2.1e-04
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0497	0.0218	7.6e-06	0.062	0.049	0.050	NA	0.057	1.7e-07	2.9e-06	2.8e-06	NA	5.5e-07
11	TCGA	Brain Lower Grade Glioma	0.3732	0.0684	2.8e-15	0.169	0.180	0.205	NA	0.211	9.8e-19	6.0e-20	7.3e-23	NA	1.8e-23
12	TCGA	Lung Squamous Cell Carcinoma	0.0322	0.0184	2.1e-03	0.012	0.015	0.001	NA	0.005	1.3e-02	7.2e-03	2.5e-01	NA	8.5e-02
13	TCGA	Pancreatic Adenocarcinoma	0.0990	0.0710	8.9e-03	0.032	0.019	0.002	NA	0.011	1.7e-02	5.3e-02	2.7e-01	NA	1.0e-01
14	TCGA	Soft Tissue Sarcoma	0.0380	0.0210	6.9e-03	0.022	0.029	0.033	NA	0.029	1.7e-02	7.2e-03	4.5e-03	NA	7.3e-03
15	TCGA	Testicular Germ Cell Tumors	0.1050	0.0610	8.9e-03	0.043	0.032	-0.004	NA	0.009	1.2e-02	2.8e-02	5.0e-01	NA	1.5e-01
16	TCGA	Thyroid Carcinoma	0.1550	0.0500	2.3e-06	0.015	0.062	0.069	NA	0.052	1.2e-02	1.0e-06	2.8e-07	NA	8.3e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Ovarian Cancer	4.2	5.5	7.4	2.2	2.6	-2.6	-2.5	1.3	2.5	-2.5	2.7	2.3	2.5	2.0	2.2	2.3	2.7	2.7	1.5
Osteoarthritis (self-reported)	3.9	5.1	7.1	2.5	2.7	-2.4	-2.3	2.5	2.3	-2.5	2.0	2.0	2.6	2.0	2.4	2.1	2.0	2.1	1.4
Worry (Nagel 2018)	3.7	7.7	14.2	-1.9	-2.8	2.6	3.4	0.2	-3.3	2.8	-1.9	-2.8	-2.8	-2.8	-3.4	-3.3	-3.8	-3.3	0.3
Stomach or abdominal pain in last month	3.6	4.5	10.0	1.5	2.3	-2.3	-1.9	3.2	2.0	-2.4	2.5	1.9	2.3	2.0	2.6	1.5	1.7	1.9	1.0
Waist circumference	3.6	13.1	21.3	3.0	4.6	-4.5	-4.2	0.6	3.9	-4.4	1.8	2.9	4.6	3.8	4.4	3.4	3.7	3.4	1.4
Impedance of whole body	3.6	18.4	30.0	-3.6	-5.1	5.3	4.8	-2.3	-4.4	5.2	-4.3	-3.9	-5.3	-2.5	-5.5	-3.8	-4.4	-3.6	-3.0
Financial difficulties in last 2 years	3.4	4.6	7.5	0.5	2.5	-2.6	-2.7	0.6	2.1	-2.1	1.9	2.6	2.4	1.4	2.4	2.0	2.7	2.7	1.2
Illnesses of siblings	3.3	4.6	8.1	-2.4	-2.8	2.5	2.0	-0.2	-2.2	2.5	-2.8	-2.3	-2.7	-1.5	-2.5	-1.5	-2.0	-1.8	-1.0
Impedance of arm (left)	3.3	15.1	25.2	-3.1	-4.4	4.8	4.1	-2.7	-3.9	4.7	-4.4	-3.5	-4.7	-2.3	-5.0	-3.5	-4.0	-3.1	-2.5
Gout (self-reported)	3.3	4.5	12.1	3.5	2.2	-2.3	-1.9	0.7	2.3	-2.6	1.1	2.2	2.2	1.9	2.4	2.1	1.6	2.2	1.2
Arm fat mass (left)	3.3	13.4	21.7	3.6	4.7	-4.6	-4.1	0.8	3.9	-4.6	1.4	3.0	4.6	3.5	4.6	3.1	3.9	3.3	1.4
Body mass index (BMI)	3.2	13.6	23.1	3.3	4.7	-4.7	-4.1	1.2	3.8	-4.6	2.4	2.9	4.8	3.6	4.8	3.1	3.8	3.1	1.3
BMI	3.1	18.1	27.4	4.3	4.9	-5.0	-4.5	2.2	4.6	-5.2	2.3	4.3	5.0	4.3	5.2	3.8	4.9	3.9	1.4
Weight	3.1	15.3	24.0	3.4	4.9	-4.9	-4.5	1.2	4.4	-4.9	1.6	3.1	4.8	3.7	4.8	3.5	4.5	3.8	1.2
Arm predicted mass (left)	3.1	15.6	24.5	3.0	4.8	-4.8	-4.6	2.1	4.5	-4.9	2.3	3.1	4.7	3.1	4.8	3.5	4.7	4.0	1.5
Impedance of leg (left)	3.0	14.4	24.2	-3.2	-4.7	4.8	4.3	-1.0	-3.9	4.6	-3.6	-3.4	-4.9	-2.1	-4.9	-3.2	-3.8	-3.3	-2.6
Arm fat mass (right)	3.0	12.5	20.8	3.5	4.6	-4.5	-4.0	0.7	3.7	-4.5	1.1	2.8	4.5	3.3	4.5	3.0	3.7	3.1	1.6
Birth weight of first child	3.0	5.5	12.2	-2.5	-2.5	2.5	1.9	-1.5	-2.2	2.8	-3.5	-2.6	-2.5	-1.9	-2.7	-2.1	-1.8	-1.6	-2.2
Leg fat mass (right)	3.0	11.6	18.6	3.0	4.3	-4.2	-3.9	0.8	3.7	-4.3	1.3	2.7	4.3	3.3	4.1	3.3	3.9	3.0	1.3
Arm fat-free mass (left)	3.0	15.0	23.1	2.9	4.7	-4.7	-4.6	2.0	4.4	-4.8	2.4	3.1	4.6	3.0	4.7	3.5	4.6	4.0	1.6
Pain experienced in last month	3.0	5.0	7.5	-0.9	-2.6	2.1	2.6	-0.8	-2.6	2.6	-1.6	-2.5	-2.4	0.8	-2.4	-2.1	-2.7	-2.7	-2.7
Illnesses of mother	2.9	3.6	7.1	-2.0	-2.3	2.2	1.9	-1.4	-2.1	2.3	-0.9	-1.3	-2.1	-2.7	-1.9	-1.5	-2.0	-2.1	0.6
Arm predicted mass (right)	2.9	14.8	23.2	2.8	4.5	-4.5	-4.4	2.3	4.6	-4.8	2.5	3.3	4.4	2.9	4.6	3.5	4.7	4.1	1.4
Pain type(s) experienced in last month: Hip pain	2.9	3.7	6.7	1.2	2.3	-1.9	-2.1	1.7	1.8	-2.4	2.6	1.9	2.2	0.7	2.2	1.5	1.6	1.4	2.2
Basal metabolic rate	2.9	16.0	24.8	3.1	4.9	-4.9	-4.8	1.6	4.6	-5.0	2.1	3.3	4.8	2.9	4.9	3.6	4.8	4.2	1.6
Unable to work because of sickness or disability	2.9	3.8	9.9	3.1	1.9	-1.7	-2.2	-0.2	1.7	-1.8	0.8	1.6	1.8	1.6	1.5	3.0	1.6	2.0	2.5
Leg fat mass (left)	2.9	11.4	18.6	3.0	4.3	-4.2	-3.9	0.6	3.7	-4.3	1.3	2.7	4.2	3.1	4.2	3.2	3.8	3.0	1.3
Leg predicted mass (left)	2.8	14.6	23.0	3.0	4.7	-4.7	-4.6	1.0	4.4	-4.8	2.2	3.1	4.7	2.5	4.7	3.4	4.6	4.0	1.7
Impedance of arm (right)	2.8	13.1	21.3	-2.5	-4.2	4.3	3.7	-2.5	-3.6	4.3	-4.6	-3.2	-4.3	-2.4	-4.6	-3.3	-3.8	-3.0	-2.1
Medication: Amlodipine	2.8	3.9	6.4	2.4	1.7	-2.0	-1.8	1.8	2.3	-2.0	0.5	2.4	1.9	2.5	1.9	1.8	2.5	2.2	0.8
Medication for hormone replacement therapy	2.7	3.0	7.3	0.8	1.7	-1.7	-1.9	1.8	1.7	-2.1	0.5	1.5	1.8	2.7	1.9	1.8	1.8	1.9	-0.6
Leg fat-free mass (left)	2.7	14.5	22.6	3.0	4.7	-4.7	-4.6	1.0	4.4	-4.8	2.2	3.1	4.7	2.5	4.6	3.4	4.6	3.9	1.8
Medication: Ramipril	2.7	3.4	6.8	1.9	2.2	-2.3	-1.7	-0.5	1.8	-2.6	1.9	1.1	2.4	0.1	2.3	1.8	1.3	0.7	2.5
Depression (self-reported)	2.7	3.2	7.3	0.7	1.8	-1.7	-2.4	-0.3	1.8	-1.7	1.0	2.4	1.6	1.9	1.3	2.3	2.4	2.7	0.7
Loud music exposure frequency	2.7	2.9	6.4	-0.8	-2.0	1.9	2.1	-0.0	-2.5	2.0	-1.0	-1.6	-1.9	-1.0	-1.9	-1.6	-2.0	-2.1	-0.7
Knee pain experienced in last month	2.7	4.2	7.5	1.1	2.2	-1.9	-2.2	0.9	2.5	-2.0	2.2	2.4	2.1	0.7	2.2	2.3	2.5	2.7	1.5
Whole body fat-free mass	2.7	15.3	23.9	3.0	4.7	-4.7	-4.7	1.7	4.6	-4.9	2.3	3.2	4.6	2.6	4.7	3.5	4.8	4.2	1.6
Whole body water mass	2.7	15.3	23.9	3.0	4.7	-4.7	-4.7	1.7	4.6	-4.9	2.3	3.2	4.6	2.8	4.8	3.5	4.8	4.2	1.6
Had menopause	2.6	3.3	6.0	-0.5	-1.8	1.8	1.9	0.2	-1.7	1.9	-2.4	-2.2	-1.7	-0.9	-2.1	-2.0	-1.8	-2.0	-2.3
Arm fat-free mass (right)	2.6	13.3	21.3	2.9	4.3	-4.3	-4.2	2.0	4.3	-4.6	2.2	3.1	4.2	2.9	4.4	3.2	4.4	3.8	1.2
Trunk fat-free mass	2.5	14.6	22.1	2.9	4.5	-4.5	-4.7	2.2	4.5	-4.7	2.0	3.1	4.5	2.6	4.6	3.5	4.6	4.1	1.7
Trunk predicted mass	2.5	14.0	21.2	2.8	4.5	-4.5	-4.5	2.3	4.4	-4.6	2.0	3.0	4.4	2.6	4.5	3.4	4.6	4.1	1.6
Comparative height size at age 10	2.5	13.7	24.2	2.7	4.1	-3.8	-4.6	-0.5	4.8	-4.0	0.9	4.7	3.7	2.1	3.9	3.6	4.9	4.7	2.0
Medication: Metformin	2.4	3.4	5.0	0.9	2.2	-2.0	-2.0	0.6	2.0	-2.1	1.8	1.8	2.1	0.8	2.1	2.2	1.8	1.8	2.2
Medication: Allopurinol	2.4	3.1	10.0	3.2	1.5	-2.0	-1.7	0.3	1.9	-2.2	0.1	2.0	1.6	1.5	1.9	1.8	1.8	1.8	0.6
Whole body fat mass	2.4	9.9	17.0	2.8	4.0	-4.0	-3.6	0.4	3.5	-4.1	0.7	2.5	4.0	2.9	3.9	2.7	3.6	2.8	1.1
Leg fat-free mass (right)	2.4	13.0	21.0	2.9	4.4	-4.5	-4.3	0.7	4.2	-4.6	2.3	3.0	4.4	2.3	4.4	3.1	4.3	3.8	1.8
Leg predicted mass (right)	2.4	12.8	20.8	2.8	4.4	-4.4	-4.3	0.8	4.2	-4.6	2.2	3.0	4.3	2.3	4.3	3.0	4.3	3.8	1.7
Type 2 Diabetes (T2D) (2018)	2.3	4.3	6.3	1.0	2.1	-2.2	-2.1	0.3	2.2	-2.5	2.5	2.4	2.1	1.7	2.1	2.5	2.2	2.1	1.8
Impedance of leg (right)	2.3	11.2	18.9	-2.8	-4.1	4.3	3.6	-0.5	-3.5	4.2	-3.4	-2.9	-4.3	-1.6	-4.4	-2.6	-3.3	-2.9	-2.5
Qualifications: CSEs or equivalent	2.3	3.0	7.0	0.7	2.1	-1.7	-2.1	1.0	1.7	-1.8	0.4	1.4	1.6	2.5	1.3	2.0	2.4	2.6	0.5
Age when periods started (menarche)	2.2	5.2	8.8	-3.0	-2.5	2.9	2.3	0.4	-2.3	2.8	-2.0	-2.8	-2.5	-1.8	-2.9	-1.3	-2.5	-1.9	-0.6
Worrier / anxious feelings	2.2	4.2	6.5	-1.8	-2.0	1.9	2.4	-0.6	-2.2	2.4	-2.1	-1.7	-2.3	-2.2	-2.5	-2.2	-2.5	-2.0	0.0
Medication: Omeprazole	2.2	2.7	5.2	2.1	1.9	-1.5	-1.9	0.3	1.5	-1.4	0.7	1.9	1.7	0.2	1.4	1.9	1.3	2.3	2.3
Qualifications: nursing, teaching	2.2	3.4	6.6	-1.7	-2.2	1.9	2.1	0.3	-1.8	2.6	-1.2	-1.5	-2.0	-1.1	-1.9	-2.1	-1.7	-1.5	-2.4
Alcohol drinker status: Never	2.2	2.6	12.1	-0.5	1.5	-1.1	-2.2	-0.5	1.5	-1.2	0.6	2.1	1.3	3.5	0.8	1.5	1.6	2.3	-0.2
Number of treatments/medications taken	2.1	3.7	7.4	2.1	2.0	-2.4	-1.7	0.6	2.1	-2.6	1.4	1.7	2.3	0.8	2.2	1.9	1.7	1.1	2.7
Multivitamins +/- minerals	2.1	2.7	5.0	-0.5	-1.8	1.6	2.2	-0.8	-2.1	1.9	-0.8	-2.2	-1.6	-0.7	-1.7	-1.8	-1.8	-1.9	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.7	12.4	1.6	2.6	-2.6	-3.0	1.5	3.2	-2.8	1.0	3.2	2.4	2.5	3.0	2.0	3.5	3.5	0.4
High blood pressure (siblings)	2.1	3.1	6.4	2.5	2.2	-1.7	-1.6	0.9	1.4	-2.0	1.6	2.1	2.0	2.2	1.9	1.3	1.1	1.6	0.8
Trunk fat mass	2.0	8.7	14.8	2.6	3.8	-3.6	-3.3	0.1	3.3	-3.9	0.2	2.3	3.7	3.1	3.6	2.5	3.3	2.7	0.7
Hip circumference	2.0	8.5	14.1	2.3	3.7	-3.8	-3.3	1.1	3.1	-3.4	1.6	2.1	3.6	3.3	3.5	2.6	3.4	2.7	0.2
Peak expiratory flow (PEF)	2.0	4.6	8.1	0.6	2.0	-2.0	-2.3	1.5	2.4	-1.9	2.2	2.8	1.9	2.5	2.6	1.8	2.7	2.8	-0.5
Medication for cholesterol, blood pressure or diabetes	2.0	3.4	8.0	-2.1	-1.9	2.2	1.8	0.6	-1.9	2.3	-0.4	-1.4	-2.2	-0.3	-1.9	-2.6	-1.5	-1.2	-2.8
Emphysema/chronic bronchitis	2.0	2.2	9.2	-3.0	-1.0	1.3	1.4	-0.9	-1.7	1.3	1.4	-1.3	-1.2	0.0	-1.2	-1.6	-1.5	-1.6	-1.5
Medication: Blood pressure	2.0	3.6	5.8	2.4	2.0	-2.4	-1.8	-0.1	2.1	-2.2	0.0	1.8	2.2	0.8	2.0	2.4	1.8	1.3	2.3
Leg pain on walking	2.0	2.5	5.4	1.6	2.3	-2.1	-1.9	-0.5	1.2	-1.6	1.4	1.2	2.3	-0.0	2.0	1.5	1.2	1.0	1.2
Age started oral contraceptive pill	2.0	2.5	4.8	-0.1	-1.6	1.9	1.7	0.0	-1.3	1.5	-2.2	-1.9	-1.7	-0.5	-1.9	-2.2	-1.5	-1.6	-1.6
Blood Platelet Count	1.9	21.5	41.7	-3.1	-5.1	4.8	5.9	-2.7	-5.5	4.6	-2.7	-5.2	-4.8	-3.4	-5.0	-3.8	-6.2	-6.5	-2.0
Ever had hysterectomy (womb removed)	1.9	2.1	5.8	0.0	-1.6	1.9	1.1	1.5	-1.2	1.3	-1.9	-1.8	-1.6	-0.1	-1.7	-1.2	-1.1	-0.8	-2.4
Angina	1.9	2.4	5.9	-0.8	-1.8	1.9	1.7	-0.5	-1.8	2.4	-1.6	-1.3	-1.8	0.3	-1.8	-1.0	-1.8	-1.2	-1.7
Maternal smoking around birth	1.9	2.7	6.6	0.3	1.5	-1.4	-1.9	-1.7	1.5	-1.1	1.6	2.6	1.4	0.4	1.2	2.4	1.5	2.2	1.9
Serious illness, injury or assault to yourself	1.9	2.3	5.1	-0.5	-1.5	1.5	1.4	0.3	-2.3	1.8	-0.9	-2.2	-1.5	-1.2	-2.2	-0.9	-1.9	-1.8	-0.2
Heart disease (mother)	1.9	2.3	4.5	0.7	2.1	-1.9	-1.7	0.4	1.2	-1.9	1.4	1.5	1.9	1.7	1.8	1.5	1.1	1.6	-0.3
Arm fat percentage (left)	1.9	7.7	13.0	2.9	3.6	-3.5	-3.1	0.0	2.8	-3.4	0.7	2.3	3.6	3.0	3.5	2.4	2.8	2.4	1.2
Allergy or Eczema	1.8	4.7	14.4	-3.8	-2.5	2.5	2.0	-2.3	-2.1	2.7	-1.7	-1.1	-2.4	-1.2	-2.1	-1.5	-1.7	-1.8	-1.6
High blood pressure	1.8	5.0	8.7	3.0	2.7	-2.7	-2.3	0.5	2.2	-2.6	0.4	2.0	2.7	2.2	2.5	2.0	1.8	1.8	2.5
Arm fat percentage (right)	1.8	7.1	12.2	3.0	3.4	-3.5	-3.0	-0.0	2.6	-3.3	0.4	2.1	3.5	2.9	3.4	2.3	2.6	2.0	1.2
Diabetes diagnosed by doctor	1.8	3.0	6.4	0.9	1.9	-1.8	-1.7	0.4	1.7	-2.0	1.8	1.8	1.8	1.2	1.8	2.5	1.4	1.6	2.2
Neuroticism (Nagel 2018)	1.7	4.0	7.3	-1.9	-2.0	1.8	2.6	0.2	-2.5	1.8	-1.3	-1.7	-2.0	-1.8	-2.3	-2.4	-2.6	-2.7	-0.0
Nervous feelings	1.7	3.1	6.3	-0.3	-1.9	1.6	2.5	-0.1	-2.1	1.7	-0.9	-2.0	-1.9	-1.7	-1.9	-2.0	-2.4	-2.4	-0.1
Medication: Ibuprofen	1.7	2.0	3.8	1.1	1.7	-1.9	-1.5	0.6	1.2	-1.9	1.2	1.2	1.7	1.6	1.6	1.5	1.3	0.7	0.8
Medication: Bendroflumethiazide	1.7	2.6	4.4	1.4	2.1	-1.9	-2.0	0.2	1.7	-1.8	0.5	1.6	1.9	1.9	1.4	1.6	1.6	2.0	0.9
Forced vital capacity (FVC), Best measure	1.6	5.7	10.1	1.2	2.4	-2.6	-2.5	1.5	3.0	-2.7	1.6	3.1	2.4	1.7	3.2	1.9	3.1	2.7	1.0
Leg fat percentage (right)	1.6	5.7	9.8	2.0	3.1	-2.9	-2.7	0.4	2.2	-2.8	0.8	1.8	3.0	3.1	2.9	2.6	2.5	1.9	0.7
Shortness of breath walking on level ground	1.6	1.9	3.4	1.6	1.7	-1.7	-1.2	-0.2	1.4	-1.6	1.1	1.2	1.7	1.8	1.8	1.1	1.2	0.8	0.3
Neck or shoulder pain in last month	1.6	2.3	5.5	0.5	2.1	-1.9	-2.2	0.1	0.8	-1.6	0.7	1.6	2.1	-0.6	1.2	1.6	1.1	1.5	2.3
Angina (self-reported)	1.6	2.2	5.3	-0.7	-1.7	1.7	1.6	-0.4	-1.7	2.3	-1.6	-1.1	-1.7	0.6	-1.7	-0.8	-1.6	-1.1	-1.7
Forced vital capacity (FVC)	1.5	5.7	10.9	1.2	2.4	-2.6	-2.5	0.6	2.9	-2.6	2.2	3.3	2.3	1.6	3.2	2.0	3.1	2.6	1.0
Hypertension (Self-reported)	1.5	4.3	8.3	2.9	2.4	-2.4	-2.0	0.7	2.0	-2.3	0.2	1.9	2.4	2.5	2.2	2.0	1.6	1.7	2.1
Hearing aid user	1.5	1.7	3.6	0.2	-1.3	0.8	1.8	1.0	-1.5	1.7	-0.3	-1.2	-1.2	-1.1	-1.2	-1.2	-1.9	-1.9	-1.1
Lupus	1.4	2.1	3.7	-0.9	-1.9	1.7	1.7	-1.0	-1.3	1.6	-0.7	-1.1	-1.8	-1.9	-1.5	-1.3	-1.5	-1.3	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.2	0.5	1.1	-0.9	-1.2	1.6	1.1	-0.6	1.6	1.3	1.0	2.1	1.4	0.8	1.3	1.9	-0.6
Wheeze or whistling in the chest in last year	1.4	2.6	5.0	0.8	1.9	-2.2	-1.8	-0.5	1.3	-1.9	1.6	2.1	2.2	1.0	2.2	1.9	0.9	0.6	0.9
Osteoporosis (self-reported)	1.4	1.7	4.3	0.4	-1.4	1.4	1.8	0.4	-1.6	1.4	-0.9	-1.4	-1.2	-0.3	-1.2	-1.0	-1.9	-2.1	-1.1
Vascular/heart problems diagnosed by doctor	1.4	3.9	7.8	-2.8	-2.4	2.4	2.0	-0.0	-1.9	2.4	-0.7	-1.7	-2.4	-1.7	-2.2	-1.8	-1.6	-1.6	-2.3
Chronotype (morning person)	1.3	3.0	5.4	-0.4	-2.3	2.3	2.2	-0.3	-1.8	2.2	-1.7	-1.2	-2.3	-1.5	-1.9	-1.5	-1.6	-2.0	-0.4
Average weekly fortified wine intake	1.3	1.5	5.7	2.4	0.8	-0.9	-0.8	-1.0	1.0	-0.6	1.7	1.6	0.7	-0.8	0.9	0.8	0.9	1.1	2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.1	5.0	-1.7	-1.9	1.7	2.1	-1.6	-2.2	1.7	-0.0	-2.2	-1.6	-1.8	-2.0	-1.4	-2.0	-2.1	-0.2
Alcohol intake versus 10 years previously	1.3	2.0	3.6	1.0	1.4	-1.4	-1.6	1.4	1.4	-1.6	-1.1	1.9	1.3	1.5	1.4	1.5	1.4	1.6	0.4
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	8.3	1.1	2.0	-2.2	-2.5	0.8	2.3	-2.1	1.5	2.7	1.8	1.9	2.5	1.8	2.8	2.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	3.2	1.2	1.4	-1.6	-1.4	0.4	1.1	-1.6	1.8	1.0	1.5	1.0	1.2	1.4	1.3	0.7	0.8
Breastfed as a baby	1.3	1.7	3.1	1.4	1.5	-1.5	-1.2	1.0	1.5	-1.5	0.4	1.3	1.4	1.2	1.6	0.9	1.8	1.2	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.1	4.6	-1.8	-1.5	1.3	1.5	0.5	-1.4	1.6	-1.8	-0.9	-1.5	0.2	-1.1	-1.6	-1.4	-1.3	-2.1
Medication: Seretide 50 evohaler	1.3	1.5	2.8	-1.3	-1.4	1.1	1.1	-0.8	-1.1	1.2	-0.7	-1.7	-1.0	-1.4	-1.0	-1.3	-0.9	-1.7	-1.3
Leg fat percentage (left)	1.3	4.8	8.4	1.7	2.9	-2.8	-2.4	0.1	2.1	-2.7	0.7	1.6	2.8	2.8	2.7	2.3	2.3	1.7	0.8
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	3.2	1.6	1.5	-1.1	-1.5	0.6	1.0	-1.2	0.3	1.3	1.4	-0.1	1.0	1.2	1.0	1.8	1.6
Ulcerative Colitis	1.2	1.7	3.6	0.6	1.5	-1.4	-1.6	0.0	1.6	-1.7	0.1	1.3	1.5	1.2	1.6	0.8	1.9	1.4	0.2
Lung FEV1/FVC ratio	1.2	6.0	17.0	1.7	2.6	-2.3	-3.4	0.3	2.6	-2.6	1.2	2.3	2.1	1.7	1.9	3.0	3.3	4.1	1.2
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.5	0.0	-1.3	1.5	1.2	0.8	-1.0	0.8	-1.5	-1.4	-1.2	0.1	-0.9	-1.2	-1.6	-1.6	-1.2
Past tobacco smoking	1.2	2.2	6.3	-1.1	-1.1	1.4	0.7	1.5	-1.4	1.6	-2.1	-1.4	-1.4	2.0	-1.5	-1.0	-1.0	-0.1	-2.5
Diabetes (self-reported)	1.2	1.8	4.7	1.0	1.4	-1.4	-1.3	1.2	1.4	-1.5	1.0	1.4	1.4	1.1	1.4	2.2	1.2	1.2	1.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.7	-0.9	1.3	-1.4	-1.2	-0.1	1.3	-1.4	1.4	0.9	1.2	1.9	1.2	0.9	1.3	1.2	-0.3
Body fat percentage	1.2	4.8	8.5	2.0	2.9	-2.8	-2.4	-0.2	2.3	-2.8	-0.0	1.7	2.8	2.7	2.7	1.9	2.3	1.8	0.5
Alcohol intake frequency.	1.2	2.7	11.0	0.5	1.6	-1.1	-2.1	0.4	1.6	-1.3	-0.1	2.0	1.4	3.3	0.9	2.3	1.4	1.9	1.3
Average weekly red wine intake	1.2	1.8	4.9	-1.3	-1.3	1.1	1.3	-0.5	-1.7	1.6	-2.2	-1.6	-1.2	-0.6	-1.1	-1.2	-0.9	-1.6	-1.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	5.3	-0.8	-1.5	1.0	0.9	0.8	-1.2	1.5	-2.3	-0.4	-1.4	0.3	-1.3	-0.4	-0.7	-0.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.6	-1.1	-0.7	0.5	1.5	1.1	-1.0	0.6	0.0	-1.9	-0.8	0.5	-0.8	-1.7	-1.4	-1.9	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.7	-0.3	1.0	-0.8	-0.7	1.5	0.9	-0.5	2.2	1.1	0.8	1.4	1.3	0.7	1.0	1.1	-0.5
Medication for cholesterol	1.1	1.6	3.4	-1.2	-1.8	1.5	1.3	-0.5	-1.0	1.6	-1.5	-0.8	-1.8	-1.5	-1.8	-1.0	-0.5	-0.9	-0.5
Eye problems/disorders: Diabetes related eye disease	1.0	1.0	4.4	1.0	1.0	-0.7	-0.9	2.1	0.7	-0.3	0.8	0.9	0.9	1.9	0.7	0.8	0.7	0.8	-0.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	4.4	-1.2	-1.2	0.6	1.2	-0.6	-1.5	1.0	-0.6	-1.2	-0.9	-0.6	-0.8	-0.5	-1.7	-2.1	0.2
Qualifications: A levels/AS levels or equivalent	1.0	2.2	3.6	-1.7	-1.6	1.4	1.4	-1.8	-1.0	1.6	-1.8	-1.5	-1.6	-1.9	-1.5	-1.7	-0.5	-1.0	-0.9
Age at first live birth	1.0	1.8	3.2	-0.2	-1.7	1.4	1.7	-1.8	-1.0	1.5	-1.2	-0.9	-1.6	-1.4	-1.2	-1.1	-1.1	-1.1	-1.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.1	-0.1	-1.1	0.4	1.5	-1.7	-0.2	0.3	-0.7	-1.1	-0.7	-2.3	-0.5	-0.8	-0.7	-1.9	0.2
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	3.8	-0.4	-1.0	1.5	1.0	0.3	-1.9	1.7	-1.1	-1.5	-1.1	-0.7	-1.6	-0.8	-1.8	-1.1	-1.2
Heart disease (siblings)	1.0	1.3	3.7	1.3	1.5	-1.6	-0.4	-0.7	0.7	-1.3	1.9	0.5	1.5	0.8	1.8	0.1	0.3	-0.3	-0.6
Bipolar Disorder (2018)	0.9	1.4	3.9	-0.5	-1.3	1.3	0.9	-0.1	-1.0	1.0	-2.0	-1.2	-1.3	-1.8	-1.4	-0.8	-0.9	-1.6	0.5
Trunk fat percentage	0.9	3.6	6.6	1.7	2.6	-2.4	-2.0	-0.6	2.0	-2.5	-0.4	1.3	2.5	2.5	2.3	1.4	2.0	1.6	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.9	1.9	3.6	-1.6	-1.3	0.9	1.6	-1.8	-1.9	1.0	0.7	-1.6	-1.0	-1.9	-1.1	-1.0	-1.5	-1.9	-0.1
Hayfever, allergic rhinitis or eczema	0.9	1.9	6.2	-2.5	-1.6	1.4	1.4	-1.6	-1.7	1.8	-0.6	-0.6	-1.4	-0.6	-1.2	-0.9	-1.1	-1.5	-1.2
Medication: Simvastatin	0.9	1.2	7.8	1.2	1.1	-1.1	-0.9	-1.1	0.6	-1.2	0.4	0.2	1.3	-0.8	0.9	1.0	0.2	-0.1	2.8
Number of live births	0.9	1.3	9.6	0.1	1.0	-0.4	-0.7	3.1	0.2	-0.5	1.5	0.7	0.5	2.0	0.2	0.9	-0.1	1.2	0.2
Medication: Cholesterol lowering	0.9	1.4	7.5	1.4	0.9	-1.4	-0.8	-0.4	0.8	-1.6	0.4	0.3	1.3	-0.4	0.9	1.8	0.5	0.1	2.7
Tense / ‘highly strung’	0.9	1.6	3.7	-0.8	-1.0	1.0	1.0	1.9	-1.6	1.4	-0.5	-0.9	-1.1	-1.3	-1.6	-0.8	-1.6	-1.3	1.2
Hair/balding pattern: Pattern 4	0.9	2.2	4.6	1.0	-1.7	1.5	2.0	-1.0	-1.4	1.0	-1.0	-1.3	-1.6	-1.9	-1.8	-1.4	-1.6	-2.1	0.4
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.8	0.4	1.4	-1.5	-1.2	-0.2	1.1	-1.2	1.5	0.9	1.5	0.3	1.7	0.8	0.7	0.6	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.0	0.7	0.9	-1.0	-1.2	-0.1	1.1	-0.8	-0.3	1.7	0.9	1.5	1.0	1.3	1.4	1.5	-0.4
Eye problems/disorders: None of the above	0.9	1.0	3.1	0.5	-1.2	1.2	0.7	-1.7	-0.1	0.7	-1.8	-1.5	-1.1	-1.0	-1.0	-0.4	-0.3	-0.8	0.4
Chest pain or discomfort	0.9	1.2	2.7	0.8	1.3	-1.5	-1.5	-0.6	0.8	-0.7	0.1	1.6	1.3	0.5	1.1	1.1	1.1	1.6	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	6.5	-1.3	-0.8	0.9	1.0	1.1	-0.7	0.6	-0.6	-1.3	-0.8	0.5	-0.6	-0.6	-0.5	-0.7	-2.5
Supplements: Vitamin C	0.9	1.0	4.9	0.1	0.6	-0.9	-0.7	-2.2	0.6	-1.0	0.8	1.2	0.7	-0.9	0.7	0.8	0.9	0.9	1.5
Illnesses of father: Heart disease	0.9	1.2	3.2	-1.5	-1.0	0.5	1.2	0.7	-1.1	0.6	-0.3	-1.1	-0.8	-1.1	-0.8	-1.8	-1.2	-1.4	-1.1
Smoking status: Previous	0.9	1.4	5.9	1.0	0.6	-1.0	-0.0	-0.3	1.0	-1.1	1.4	0.8	0.9	-2.4	1.0	0.3	0.7	-0.4	2.4
Long-standing illness, disability or infirmity	0.9	1.3	4.4	1.2	1.1	-1.6	-0.7	0.2	0.7	-1.0	2.1	1.0	1.3	0.8	1.0	1.8	0.7	0.4	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	4.0	1.2	1.5	-1.4	-1.6	0.6	1.8	-1.5	0.7	1.4	1.4	1.5	1.6	0.8	1.9	2.0	0.2
Ever smoked	0.9	1.6	3.8	1.0	0.9	-1.1	-0.9	-1.6	1.4	-1.5	1.9	1.4	1.1	-1.5	1.3	0.9	0.8	0.6	1.5
Basal cell carcinoma (self-reported)	0.9	1.0	5.2	-0.2	-0.8	1.0	0.7	0.5	-0.7	0.6	-1.8	-0.7	-0.8	0.9	-0.8	-1.2	-0.5	-0.4	-2.3
Alzheimer’s Disease (in father)	0.8	0.8	2.0	1.2	0.9	-1.0	-0.8	-0.3	0.7	-1.0	1.0	0.7	0.9	0.2	1.0	1.4	0.7	0.5	1.3
Relative age voice broke	0.8	1.3	3.4	-1.1	-1.3	1.5	1.0	0.4	-1.0	1.7	-1.2	-1.2	-1.5	-0.4	-1.9	-0.3	-0.8	-0.2	-0.7
Allergy	0.8	1.8	7.3	2.7	1.4	-1.4	-1.3	1.2	1.6	-1.3	0.0	0.7	1.3	0.2	1.2	1.0	1.4	1.4	0.9
Lung cancer (father)	0.8	1.0	3.6	-0.2	0.8	-0.8	-0.7	-1.6	0.7	-1.1	0.5	1.1	0.9	1.9	1.0	1.3	0.4	0.5	0.3
Length of working week for main job	0.8	0.9	2.2	1.0	0.5	-0.8	-1.3	1.1	1.0	-0.6	-0.6	0.7	0.5	0.2	0.7	1.4	1.4	1.5	0.5
Ever highly irritable/argumentative for 2 days	0.8	1.0	4.6	-0.1	1.3	-0.9	-1.0	-0.6	0.5	-1.1	0.6	1.3	1.2	-0.1	0.7	1.1	0.7	0.8	2.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.7	-1.6	-1.1	1.2	1.1	-0.7	-0.7	1.4	-1.2	-1.0	-1.2	-1.1	-1.2	-1.4	-0.3	-0.5	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	4.5	-0.9	-1.2	0.9	1.1	0.3	-0.3	0.8	-0.9	-0.9	-1.2	-0.8	-0.7	-1.2	0.1	-0.9	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.2	-1.5	-1.1	1.2	0.5	1.0	-1.1	1.0	-1.4	-0.7	-1.1	-0.3	-1.2	-0.5	-0.9	-0.6	-0.5
Medication: Aspirin	0.8	1.0	2.7	-1.1	-1.1	1.0	1.2	0.8	-1.1	1.0	-0.5	-1.6	-1.0	-0.7	-1.1	-1.1	-0.9	-0.9	-0.3
Number of self-reported non-cancer illnesses	0.8	1.4	3.4	0.6	1.4	-1.2	-1.2	0.6	0.9	-1.7	0.0	0.8	1.5	1.4	0.9	1.8	0.4	0.7	1.8
Irritable Bowel Disease (IBD)	0.7	1.6	3.7	0.9	1.3	-1.4	-1.2	0.9	1.4	-1.6	0.5	1.5	1.3	-1.0	1.6	1.0	1.3	0.9	1.9
Coronary Artery Disease (CAD)	0.7	0.8	4.7	0.6	0.6	-0.7	-0.8	-0.7	0.6	-0.8	0.1	1.0	0.8	-0.1	0.8	2.2	0.2	0.2	1.4
HbA1C	0.7	0.7	4.9	0.0	-1.2	0.1	0.6	-0.7	-0.1	0.9	-2.2	0.4	-1.3	-0.8	-1.0	0.1	-0.6	-0.3	0.1
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.3	1.5	0.5	-0.4	-1.0	1.0	0.9	-0.4	-0.5	0.6	0.4	1.5	0.4	0.9	1.1	1.1	0.7
Lung FVC	0.7	3.6	5.5	0.8	2.3	-2.3	-2.1	0.8	2.2	-2.0	2.2	2.3	2.1	1.4	2.3	1.2	2.2	1.8	1.1
Neuroticism	0.7	1.7	3.3	-0.8	-1.2	1.1	1.7	0.4	-1.8	1.1	-1.3	-1.2	-1.4	-0.7	-1.5	-1.6	-1.6	-1.4	-0.4
Vitamin and mineral supplements	0.7	1.0	2.1	0.4	1.2	-0.8	-1.2	1.5	1.3	-1.0	0.4	1.1	1.0	0.8	1.1	0.7	1.0	1.0	0.1
Townsend deprivation index at recruitment	0.7	1.0	3.5	1.9	0.8	-0.9	-0.8	0.1	0.7	-0.4	0.7	1.5	0.9	0.9	1.3	1.0	0.8	0.2	1.3
Taking other prescription medications	0.7	1.1	3.2	1.0	1.0	-1.3	-0.5	1.5	0.8	-1.4	1.8	1.0	1.3	0.2	1.1	0.7	0.4	0.4	1.2
Medication: Levothyroxine sodium	0.7	1.2	3.6	0.4	1.1	-1.4	-0.8	0.8	1.0	-1.0	1.3	0.5	1.3	1.9	1.2	1.3	1.1	0.5	-0.8
Time employed in main current job	0.7	0.8	1.8	1.2	0.8	-0.8	-0.7	-0.9	0.9	-1.0	-0.0	0.7	0.8	0.9	1.2	1.3	0.7	-0.1	1.1
Happiness	0.7	0.8	1.8	-0.1	-1.3	0.9	1.0	0.7	-0.7	0.9	-1.2	-0.9	-1.1	-0.7	-1.1	-0.6	-0.7	-1.3	-0.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.7	0.8	1.3	-1.5	-1.2	0.9	1.1	-1.2	1.6	0.6	1.5	1.1	1.3	1.3	1.0	0.7	0.2
Exposure to tobacco smoke outside home	0.7	0.9	2.8	1.4	0.6	-0.5	-0.8	-0.7	0.9	-0.5	0.9	1.7	0.5	-1.0	0.5	1.0	1.0	1.1	1.5
Comparative body size at age 10	0.7	2.0	4.3	2.0	1.7	-2.1	-1.1	0.8	1.6	-1.9	0.2	1.0	1.5	1.2	2.1	0.5	1.7	0.8	-0.3
Had major operations	0.7	0.8	1.8	0.6	1.0	-1.2	-0.7	0.3	1.0	-1.3	0.4	1.0	1.2	0.5	1.1	0.7	1.0	0.8	0.7
Commuting to job workplace: Walk	0.7	0.8	2.0	1.1	1.0	-0.8	-0.8	0.3	1.0	-0.8	0.5	1.4	1.1	0.6	1.0	1.0	0.5	0.9	1.0
Illnesses of father: None of the above (group 1)	0.7	0.8	2.6	0.8	0.3	-0.1	-0.9	0.2	1.1	-0.4	-1.0	0.8	0.2	1.6	0.2	1.3	1.5	1.3	-0.7
Wears glasses or contact lenses	0.7	0.8	2.7	-0.3	-0.6	0.3	1.0	-0.6	-0.6	0.4	-1.6	-1.2	-0.6	0.1	-0.6	-1.1	-0.8	-1.2	-1.5
Verbal and Numeric Reasoning (VNR)	0.6	1.4	4.0	0.0	0.9	-0.8	-1.6	0.8	1.4	-0.3	-0.5	0.9	0.9	1.7	0.7	1.0	1.9	2.0	-1.1
Bipolar Disorder (2011)	0.6	0.6	1.5	0.6	0.6	-0.8	-0.9	0.0	0.9	-0.7	-0.3	1.0	0.5	0.0	1.0	0.8	1.2	1.1	0.0
Alcohol usually taken with meals	0.6	1.0	1.9	-1.0	-0.9	0.9	1.1	-0.6	-1.4	1.1	-0.8	-1.1	-0.9	-1.2	-1.0	-0.9	-1.0	-1.2	-0.7
Exposure to tobacco smoke at home	0.6	0.7	1.7	0.0	-0.6	0.9	0.8	-0.6	-0.7	0.5	0.5	-0.5	-0.6	-1.3	-1.1	-0.2	-1.1	-1.0	1.3
Number of full brothers	0.6	0.8	3.8	0.7	0.4	-0.3	-0.6	0.3	0.5	-0.4	0.9	1.1	0.5	2.0	0.8	0.4	0.6	1.1	-1.6
Suffer from ‘nerves’	0.6	1.0	2.3	0.3	-0.7	0.4	1.2	0.7	-1.3	0.7	-0.3	-1.2	-0.6	-1.5	-0.8	-1.0	-1.4	-1.4	0.8
Family relationship satisfaction	0.6	0.7	2.2	-0.2	-0.9	1.1	0.6	0.4	-0.8	1.3	-0.5	-1.1	-0.9	-0.3	-1.5	-0.3	-0.6	-0.5	-1.0
Illnesses of siblings: Diabetes	0.6	0.8	3.0	0.1	1.2	-0.6	-0.7	-0.8	0.6	-0.7	1.7	0.5	0.9	-1.2	0.6	0.8	0.4	0.9	1.0
Fractured/broken bones in last 5 years	0.6	0.8	2.6	-1.0	-0.4	0.3	0.6	1.6	-1.1	0.9	-1.3	-0.8	-0.6	-0.5	-0.9	-1.1	-0.8	-0.8	-0.8
Depression (Nagel 2018)	0.5	0.7	1.6	-0.5	-0.8	0.7	1.0	-0.2	-1.2	0.5	-0.5	-0.4	-0.7	-0.8	-0.8	-0.8	-1.3	-1.2	-0.8
Intelligence (Savage-Jansen 2018)	0.5	1.7	4.0	1.1	1.2	-0.9	-1.8	0.5	1.4	-0.6	-0.8	1.0	1.1	2.0	1.2	1.6	1.7	2.0	-0.5
Ulcerative Colitis (UC)	0.5	1.0	1.8	1.4	1.0	-1.2	-1.0	0.6	1.1	-1.2	-0.7	1.0	1.1	-0.5	1.2	0.7	1.2	0.5	1.2
Sensitivity / hurt feelings	0.5	0.9	2.2	-0.7	-1.1	0.9	1.1	0.8	-1.2	0.9	-0.4	-0.6	-1.1	-1.5	-1.1	-0.9	-0.6	-1.0	0.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.5	0.3	0.8	-1.1	-0.6	0.3	0.7	-0.9	0.7	0.2	1.0	1.2	1.0	0.9	0.5	0.4	-0.8
Sitting height	0.5	3.2	6.8	0.4	2.0	-2.1	-2.1	0.2	2.6	-2.4	0.9	1.6	1.9	0.6	2.1	1.3	2.6	2.4	0.6
Chronic bronchitis/emphysema (father)	0.5	0.6	3.9	0.2	0.7	-0.5	-0.1	-1.1	0.5	-1.1	2.0	0.7	0.7	-0.2	1.0	-0.3	-0.2	0.2	0.6
Father’s age at death	0.5	0.6	2.9	-0.2	-0.5	0.7	0.5	1.0	-0.3	0.8	-1.3	-0.8	-0.7	0.6	-0.6	-0.8	-0.1	0.1	-1.7
Medication: Ventolin 100micrograms inhaler	0.5	0.6	3.0	0.4	0.6	-0.5	-0.7	1.7	0.9	-0.9	-0.3	0.7	0.6	0.8	0.6	0.6	0.9	0.7	0.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	3.2	-0.6	-0.5	0.6	0.5	1.8	-0.8	0.5	-0.5	0.4	-0.4	1.3	-0.3	-0.4	-1.0	-0.6	0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	5.7	-0.6	-0.3	0.4	0.3	-1.2	-0.2	0.2	0.1	-0.1	-0.1	-2.4	-0.5	-0.3	-0.4	-0.4	1.1
Ever had bowel cancer screening	0.5	0.6	3.2	-1.8	-0.0	-0.1	0.6	-0.1	-0.3	-0.3	0.2	-0.3	0.2	-1.4	-0.1	-0.2	-1.0	-1.2	0.8
Eye problems/disorders: Cataract	0.5	0.6	2.2	-1.2	-0.1	0.1	0.7	0.9	-1.5	0.9	0.4	-0.2	-0.4	0.5	-0.6	-0.6	-1.0	0.0	-1.3
Medication: Gliclazide	0.5	0.6	0.9	1.0	0.9	-1.0	-0.7	-0.5	0.9	-0.9	0.6	0.4	0.9	-0.2	0.8	0.7	0.6	0.8	0.7
Ever taken oral contraceptive pill	0.5	0.6	3.8	0.2	-0.7	0.6	0.2	-1.9	0.3	0.1	1.6	-0.4	-0.7	-0.5	-0.3	-0.1	-0.0	0.0	-0.9
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.2	0.7	-0.3	0.3	0.8	0.3	-1.3	0.8	0.8	-1.5	-0.2	0.1	-0.6	-0.5	-1.3	-1.2	-0.4
Medication: Atorvastatin	0.5	0.6	3.2	0.4	-0.5	0.6	0.8	0.5	-0.9	0.6	-1.8	-0.8	-0.7	0.5	-0.7	-0.4	-1.1	-0.5	-0.4
Illnesses of father: High blood pressure	0.5	0.7	2.1	-0.3	-0.4	0.7	1.0	1.0	-0.8	0.5	-0.1	-0.7	-0.6	-1.3	-0.8	-0.9	-1.5	-0.7	0.5
Risk taking	0.5	0.8	4.5	-0.8	-0.6	0.7	0.6	2.1	-0.9	0.6	0.6	-0.3	-0.5	-0.1	-0.8	-0.7	-1.0	-0.3	-1.2
Myopia	0.5	0.8	2.9	0.1	0.5	-0.4	-0.8	-1.7	0.9	-0.5	-0.4	1.2	0.5	-0.1	0.5	1.3	1.4	0.8	1.0
Alcohol drinker status: Previous	0.5	0.6	2.0	-1.0	0.8	-0.9	-0.8	-1.4	0.5	-0.2	1.0	0.7	0.7	0.3	0.6	0.7	0.7	0.6	0.7
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-0.3	-0.5	0.2	0.6	0.8	-0.8	0.3	0.2	-0.8	-0.5	-1.1	-0.6	-1.3	-1.2	-0.4	-0.3
Major Depression (MDD)	0.4	0.5	1.5	-1.1	0.5	-0.2	-0.6	0.0	0.4	-0.6	1.2	0.2	0.5	1.0	0.5	0.6	0.3	0.9	-0.8
Age at First Birth	0.4	0.5	2.2	0.4	-0.7	0.6	0.2	-0.6	-0.1	1.1	-1.5	-0.5	-0.9	-0.6	-0.6	0.1	0.1	0.2	-1.4
Crohns Disease (2012)	0.4	0.6	2.4	-1.5	-1.0	0.8	0.7	1.5	-0.3	0.8	-0.5	-0.0	-0.8	-1.1	-0.5	-0.2	-0.4	-0.3	-0.1
Mean Putamen Volume	0.4	0.5	1.9	-0.1	-0.6	0.7	0.4	-1.4	-0.0	0.0	-1.3	-0.6	-0.5	-0.6	-0.5	-0.8	-0.6	-0.7	-0.3
Fasting Glucose	0.4	0.4	1.7	-1.3	-0.3	0.7	0.6	1.0	-0.1	0.3	0.1	-0.1	-0.4	0.0	-0.3	-1.3	-0.1	-0.2	-1.2
Height	0.4	8.5	18.3	1.4	2.9	-2.7	-3.5	0.6	4.2	-3.7	0.1	3.0	2.8	1.9	3.1	3.1	4.3	3.9	0.7
Relative age of first facial hair	0.4	0.8	1.9	-0.6	-1.0	0.7	1.0	1.4	-1.1	1.3	-0.3	-0.7	-1.0	-0.0	-1.1	-0.2	-0.9	-0.6	-0.9
Medication: Co-codamol	0.4	0.5	2.5	0.7	0.7	-0.5	-0.6	0.1	0.9	-0.8	0.8	1.6	0.7	0.4	0.7	0.5	0.2	0.6	0.7
Hand grip strength (right)	0.4	1.2	5.4	-2.3	-0.7	0.7	0.1	1.0	-1.2	1.2	0.5	-1.0	-1.0	1.4	-1.2	-0.1	-0.4	0.5	-1.8
High blood pressure (mother)	0.4	0.5	3.1	1.8	0.8	-0.5	-0.4	0.6	0.7	-0.8	-0.4	0.4	0.6	0.6	0.3	0.2	0.6	0.2	1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.7	-1.1	0.5	-0.5	-0.4	0.5	0.5	-0.6	1.3	1.1	0.4	0.7	0.4	0.9	0.5	0.4	0.0
Pain all over the body in last month	0.4	0.4	2.3	0.2	-0.7	0.4	0.9	-0.3	-0.2	0.5	0.3	0.1	-0.4	-1.5	-0.1	-1.0	-0.4	-1.0	-0.3
Medication: Lansoprazole	0.4	0.5	2.4	-0.5	-0.3	-0.1	0.6	-0.9	-0.0	0.6	1.3	0.1	-0.1	-1.5	-0.3	-0.7	-0.2	-0.6	1.1
Headache pain in last month	0.4	0.6	2.5	-0.1	0.3	0.0	-1.0	0.8	0.3	-0.4	-0.3	1.3	0.1	1.6	-0.1	0.7	0.8	1.5	0.6
Glaucoma (self-reported)	0.4	0.5	2.3	1.0	0.2	-0.3	-0.3	0.0	0.5	-0.1	-1.5	0.9	0.3	1.1	0.7	0.4	0.4	0.5	-1.0
Birth weight	0.4	0.8	4.8	-0.0	-0.1	0.1	-0.1	2.1	0.0	0.3	-1.4	-0.3	-0.2	2.2	0.1	0.7	0.1	-0.2	-0.7
Number of children fathered	0.4	0.5	1.9	-1.0	0.2	-0.3	0.6	-0.1	-0.4	-0.0	1.4	-0.9	0.3	-1.1	0.6	-0.1	-0.5	-1.3	0.5
Health satisfaction	0.4	0.5	1.0	-0.1	-0.8	0.8	0.6	-0.8	-0.7	1.0	-1.0	-0.5	-0.8	0.2	-0.9	-0.5	-0.2	-0.5	-1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.9	-0.2	-0.5	0.3	0.6	0.2	-0.9	0.5	-1.4	-0.6	-0.6	0.1	-0.5	-0.3	-0.5	-0.6	-1.2
Medication: Aspirin	0.4	0.5	1.6	-0.7	-0.6	0.5	0.7	0.6	-0.8	0.4	0.1	-1.3	-0.5	-1.1	-0.8	-0.8	-0.6	-0.5	0.4
Mood swings	0.4	0.7	1.9	-0.1	1.1	-1.4	-0.8	0.2	0.2	-1.0	0.9	0.6	1.1	0.8	0.9	1.3	0.7	0.1	0.9
Loneliness, isolation	0.4	0.6	2.0	0.7	-0.7	0.7	1.1	-1.4	-0.5	0.6	-0.2	0.2	-0.5	-1.0	-0.9	-0.6	-0.7	-1.0	0.2
Friendships satisfaction	0.4	0.5	1.7	1.0	0.1	-0.2	-0.7	1.3	0.3	0.7	-0.3	0.2	0.1	1.2	-0.1	0.8	1.1	0.7	-0.8
Guilty feelings	0.4	0.5	2.1	-0.6	-0.6	0.7	0.2	-0.3	-0.4	1.0	-1.5	0.6	-0.6	0.8	-0.6	-1.0	-0.0	0.2	-1.0
Mother’s age at death	0.4	0.5	1.0	0.4	0.8	-0.5	-0.6	1.0	0.8	-0.8	0.8	0.6	0.6	0.0	0.6	0.6	0.6	1.0	0.4
Commuting to job workplace: Public transport	0.4	0.5	1.9	-0.4	0.5	-0.4	-0.1	1.1	0.5	-0.5	1.4	0.8	0.5	-0.1	0.4	-0.1	0.3	0.2	1.3
Commuting to job workplace: Cycle	0.4	0.5	2.6	-0.5	0.1	-0.1	-0.1	1.3	1.0	-0.5	1.6	0.2	0.0	0.1	0.4	0.0	1.1	0.7	-0.1
Bipolar Disorder or Schizophrenia	0.3	0.7	2.5	-0.6	-0.9	1.0	0.6	-0.3	-0.7	0.9	-0.3	-0.6	-0.9	-1.6	-1.0	-0.1	-0.8	-1.1	1.0
Schizophrenia vs Biploar Disorder	0.3	0.4	1.0	0.6	0.8	-0.8	-0.2	0.0	0.3	-0.3	1.0	0.9	0.7	0.8	0.9	0.3	0.2	0.7	-0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	0.8	0.8	0.8	-0.8	-0.7	0.6	0.1	-0.7	0.9	0.2	0.7	-0.5	0.6	0.3	0.1	0.6	0.8
Reaction Time	0.3	0.5	3.9	0.3	0.2	0.0	0.0	-0.7	-0.0	-0.6	-0.3	0.6	0.1	-2.0	0.1	-0.0	-0.2	-0.4	1.5
Breast Cancer	0.3	0.7	5.7	0.8	0.1	0.6	-0.2	-0.5	-0.3	0.2	-2.4	-0.0	-0.3	0.9	-0.3	0.1	-0.1	0.9	-1.4
HDL Cholesterol	0.3	0.5	3.1	-0.6	0.3	-0.2	-0.4	-1.8	0.7	-0.2	1.3	0.6	0.3	0.5	0.4	0.5	0.6	0.8	-0.3
LDL Cholesterol	0.3	0.5	2.1	1.1	0.6	-0.6	-0.1	0.2	0.3	-0.7	0.5	0.5	0.7	-1.1	0.8	0.2	-0.3	-0.5	1.4
Rheumatoid Arthritis	0.3	0.3	1.6	1.2	-0.2	0.2	-0.0	-0.9	0.0	0.2	-1.3	-0.6	-0.3	-0.2	-0.7	-0.1	0.0	0.1	-0.7
Triglycerides	0.3	0.5	2.0	-0.3	0.1	0.3	0.7	0.6	-0.8	0.2	0.7	-0.7	-0.1	-1.0	-0.2	-1.4	-0.9	-0.8	-0.3
Waist Hip Ratio (WHR)	0.3	1.5	2.9	0.7	1.4	-1.4	-1.7	-0.5	1.6	-1.5	0.0	1.0	1.4	1.5	1.3	1.0	1.2	1.5	0.5
Smoking Status	0.3	0.7	4.4	-0.6	0.1	-0.2	-0.0	-1.0	0.1	-0.2	1.8	0.5	0.1	-2.1	0.3	-0.1	-0.1	-0.2	1.0
Hypothyroidism (self reported)	0.3	0.6	2.8	0.9	0.6	-0.8	-0.5	0.5	0.6	-0.6	1.7	0.4	1.0	0.7	0.9	1.0	0.4	-0.1	0.1
Hand grip strength (left)	0.3	0.9	4.2	-1.8	-0.4	0.3	-0.1	0.7	-0.5	0.5	0.8	-0.4	-0.7	1.8	-0.3	0.3	-0.1	0.7	-2.0
Average weekly spirits intake	0.3	0.3	0.8	0.8	0.8	-0.6	-0.4	-0.9	0.4	-0.3	0.6	0.3	0.5	-0.4	0.5	0.7	0.4	0.5	-0.3
Diabetes (father)	0.3	0.4	1.3	0.1	0.6	-0.5	-1.1	0.2	0.4	-0.7	-0.9	-0.2	0.6	-0.3	0.2	0.5	0.3	0.7	0.9
Diabetes (mother)	0.3	0.4	1.1	0.1	0.4	-0.5	-0.2	1.1	0.3	-0.8	0.8	0.1	0.4	0.8	0.5	1.1	0.4	-0.4	0.8
Severe depression (siblings)	0.3	0.4	2.0	-0.0	-0.4	0.2	-0.0	-0.5	0.5	0.1	1.2	1.4	-0.3	-0.9	0.3	0.1	0.3	0.2	0.6
Pack years adult smoking proportion	0.3	0.5	3.0	1.3	0.3	0.1	-0.4	-0.8	-0.6	0.5	-1.7	-0.1	0.2	-0.5	-0.4	0.4	-1.0	0.3	0.7
Fluid intelligence score	0.3	0.6	1.8	0.2	0.2	-0.0	-0.8	1.1	0.9	-0.0	-0.3	0.4	0.3	1.1	-0.0	0.4	1.1	1.3	-1.3
Hair/balding pattern: Pattern 3	0.3	0.5	1.4	-0.6	0.3	0.1	-1.0	0.2	0.6	0.2	-1.1	1.2	0.1	0.9	0.4	0.7	0.6	1.1	-0.1
Mouth/teeth dental problems: Dentures	0.3	0.6	1.3	0.5	0.9	-0.9	-0.7	0.9	0.6	-1.0	0.8	0.6	1.0	1.0	1.1	0.5	0.5	-0.0	-0.2
Qualifications: College or University degree	0.3	0.9	3.4	-0.8	-0.8	0.8	0.8	0.4	-1.0	1.6	-0.4	-1.1	-0.8	-0.0	-1.0	-1.0	-0.3	-0.4	-1.8
Mean time to correctly identify matches	0.3	0.6	3.8	0.3	0.5	-0.1	-0.1	-0.5	0.2	-0.8	-0.6	0.4	0.3	-1.9	0.0	-0.2	0.1	-0.3	1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.2	0.6	0.5	-0.5	-0.9	-0.8	0.9	-0.7	-0.5	0.8	0.5	0.0	0.3	0.4	1.1	1.5	0.7
Back pain experienced in last month	0.3	0.4	1.9	-0.2	0.7	-0.4	-0.3	0.2	0.4	-0.6	1.4	0.6	0.5	-0.6	0.8	0.5	0.3	0.2	1.2
Mineral and other dietary supplements	0.3	0.5	1.7	-1.1	-0.2	0.5	-0.5	-0.7	0.7	-0.0	-0.9	0.8	-0.5	0.4	-0.4	0.2	0.7	1.3	-0.6
Financial situation satisfaction	0.3	0.3	1.5	0.2	-0.7	0.6	0.7	-0.5	-0.5	0.8	-0.0	-0.1	-0.5	-1.2	-0.5	-0.4	-0.2	-0.8	-0.2
High cholesterol (Self-reported)	0.3	0.5	2.6	1.6	0.6	-0.9	-0.7	-0.1	0.4	-0.6	-0.5	-0.1	0.8	0.4	0.5	0.6	0.1	0.3	1.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	-0.6	-0.3	0.4	0.7	-1.1	-0.2	0.2	0.4	-0.8	-0.3	0.2	-0.6	-0.5	-0.6	-0.9	0.3
Diastolic blood pressure, automated reading	0.3	0.8	2.1	0.6	-0.8	0.9	1.0	-0.3	-0.9	0.7	-1.5	-0.6	-1.0	1.1	-0.9	-1.2	-0.9	-0.7	-0.9
Supplements: Calcium	0.3	0.4	2.9	1.7	-0.0	-0.4	0.2	-1.1	-0.2	0.0	-0.5	0.2	0.3	-0.3	0.3	0.4	-0.1	-0.5	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	0.8	0.7	-0.4	-0.6	-0.8	0.9	-0.7	0.4	0.6	0.6	-0.3	0.6	0.5	0.2	0.8	0.4
Pack years of smoking	0.3	0.5	3.5	1.1	0.4	-0.0	-0.4	-0.6	-0.5	0.3	-1.9	-0.1	0.3	-0.6	-0.4	0.4	-1.0	0.1	0.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.0	-0.6	-0.3	0.1	1.0	0.7	-1.0	0.1	0.5	-0.3	-0.4	0.3	-0.7	-0.6	-0.7	-1.0	-0.2
Crohns Disease (2017)	0.2	0.4	2.4	-0.6	-0.0	0.0	0.2	0.8	0.1	-0.3	1.0	0.6	0.1	-1.6	0.3	0.2	-0.1	-0.0	1.4
Prostate Cancer	0.2	0.3	1.5	-0.1	0.5	-0.2	-0.3	-0.3	0.4	-0.3	0.5	1.2	0.5	0.2	0.9	-0.2	0.4	0.8	-1.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.4	0.6	0.6	-0.6	-0.2	-0.3	0.5	-0.4	1.2	0.8	0.6	0.2	0.6	0.1	0.1	0.4	0.0
Primary Biliary Cirrhosis	0.2	0.3	1.7	-1.1	-0.1	0.5	-0.2	0.5	-0.1	0.4	-1.3	0.3	-0.3	0.6	-0.5	0.2	0.4	0.7	0.2
Blood White Count	0.2	1.4	6.9	-0.1	-0.7	0.3	0.9	-1.9	-1.0	0.5	-0.4	-1.0	-0.3	-2.6	-0.4	-0.6	-1.5	-2.1	1.2
Systolic Blood Pressure	0.2	0.8	4.2	0.8	-0.6	0.8	0.6	-1.3	-0.7	0.5	-2.0	-0.6	-0.6	0.6	-0.6	-1.1	-0.8	-0.7	-1.0
Cardiovascular Disease	0.2	0.7	3.9	1.9	0.6	-0.4	-0.6	0.4	0.6	-0.5	-0.5	0.6	0.6	2.0	0.5	0.7	0.3	0.9	0.0
Hearing difficulty/problems: Yes	0.2	0.3	1.5	0.4	-0.2	-0.1	0.0	0.7	0.4	0.0	0.7	0.5	-0.0	0.6	0.2	-0.1	0.8	0.3	-1.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.3	1.1	0.3	-0.3	-0.1	-0.6	0.1	-0.6	0.6	-0.2	0.4	-0.7	-0.0	-0.4	-0.2	-0.3	-0.1
Systolic blood pressure, automated reading	0.2	0.5	2.1	0.8	-0.3	0.4	0.7	-0.9	-0.7	0.2	-1.4	-0.5	-0.3	0.7	-0.4	-0.6	-0.9	-1.0	-0.4
Supplements: Zinc	0.2	0.3	1.1	1.0	0.4	-0.3	0.1	-0.9	-0.3	0.0	-0.6	0.2	0.3	-1.1	0.1	-0.0	0.3	-0.1	0.6
Current tobacco smoking	0.2	0.3	1.9	-0.4	-0.1	0.1	-0.2	-1.4	-0.6	0.1	0.8	-0.4	-0.1	-0.1	-0.1	0.2	-0.8	-0.4	0.2
Fed-up feelings	0.2	0.3	1.8	-0.6	0.2	-0.3	0.3	1.4	-0.2	-0.4	1.0	0.0	0.0	0.5	0.0	0.2	0.2	-0.5	0.6
Supplements: Glucosamine	0.2	0.3	0.5	0.7	0.7	-0.7	0.2	-0.1	0.5	-0.7	0.6	-0.1	0.7	0.0	0.5	0.2	0.6	-0.2	0.4
Medication: Atenolol	0.2	0.3	1.5	0.2	0.2	0.0	-0.0	0.7	0.0	-0.2	-1.2	-0.1	0.2	0.5	0.4	-0.6	-0.2	0.3	-1.1
Hearing difficulty/problems with background noise	0.2	0.3	1.6	-0.1	-0.4	0.2	0.4	-0.4	-0.5	0.6	0.5	-0.8	-0.3	-0.2	-0.5	-0.4	0.1	-0.4	-1.3
Had other major operations	0.2	0.2	1.5	0.3	0.4	-0.4	-0.4	0.5	0.1	0.1	0.4	0.0	0.3	1.2	0.2	0.5	0.4	0.5	-0.5
Qualifications: None of the above	0.2	0.5	2.9	1.7	0.3	-0.4	-0.1	0.5	-0.1	-0.4	0.5	0.8	0.3	1.5	0.4	0.4	-0.5	-0.4	0.5
Mouth/teeth dental problems	0.2	0.3	1.5	0.9	0.1	-0.3	-0.4	-0.2	0.8	-0.2	-0.4	0.6	0.0	0.1	0.2	0.2	1.2	1.0	-0.5
Heart attack	0.2	0.3	0.8	0.5	0.6	-0.3	-0.5	-0.9	0.7	-0.5	0.5	0.5	0.5	-0.5	0.4	0.4	0.0	0.7	0.4
Neuroticism score	0.2	0.5	1.2	-0.4	-0.6	0.5	0.9	0.2	-1.1	0.7	-0.6	-0.2	-0.9	-0.5	-1.0	-0.7	-0.8	-0.6	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.8	-0.5	0.3	-0.6	-0.0	1.3	-0.1	-0.1	0.8	0.1	0.3	0.9	0.5	0.0	-0.2	-0.1	-0.2
Falls in the last year	0.2	0.2	0.7	0.5	0.4	-0.5	-0.2	-0.5	0.6	-0.8	0.2	0.5	0.6	0.8	0.8	0.1	0.3	0.1	0.4
Pulse rate	0.2	0.3	0.7	-0.2	-0.3	0.3	0.6	-0.8	-0.7	0.1	-0.8	-0.8	-0.3	0.2	-0.4	-0.4	-0.7	-0.8	-0.5
Noisy workplace	0.2	0.3	1.1	-1.0	-0.4	0.5	0.0	-0.5	-0.1	0.2	0.1	0.5	-0.3	-0.7	-0.3	0.4	-0.5	0.2	0.9
Prospective memory result	0.2	0.2	1.2	-0.3	-0.0	0.1	0.4	0.2	-0.7	0.3	-0.3	-0.4	-0.1	-0.0	-0.1	-0.6	-0.7	-0.6	-1.1
Pulse wave Arterial Stiffness index	0.2	0.3	2.3	-1.5	0.6	-0.4	-0.3	-0.7	-0.0	-0.0	-0.1	-0.6	0.4	-0.1	0.2	-0.1	-0.3	-0.0	0.1
Worry too long after embarrassment	0.2	0.3	1.6	0.2	-0.2	0.1	0.6	-0.3	-0.5	0.1	-1.1	-0.1	-0.3	-1.3	-0.4	-0.4	-0.6	-0.4	0.6
Pulse wave peak to peak time	0.2	0.2	2.0	1.4	-0.6	0.4	0.2	0.7	0.1	-0.1	-0.0	0.7	-0.4	0.2	-0.2	0.2	0.4	0.2	-0.2
Medication for pain relief, constipation, heartburn	0.2	0.4	2.4	-0.2	-0.5	0.5	0.6	-1.1	-0.5	0.8	-0.6	0.0	-0.5	0.1	-0.3	-0.3	-0.6	-0.2	-1.6
Pulse rate, automated reading	0.2	0.7	1.7	-0.8	-0.5	0.7	0.5	-1.2	-1.3	0.8	-1.2	-0.9	-0.6	-0.5	-0.9	-0.6	-1.1	-0.8	-0.2
Overall health rating	0.2	0.4	1.5	1.2	0.6	-0.7	-0.6	-0.2	0.7	-0.6	0.2	0.8	0.7	0.6	0.6	0.6	0.6	0.4	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.6	-0.8	-0.4	0.3	0.5	0.1	-0.6	0.8	-0.2	-0.2	-0.4	-0.5	-0.3	-0.6	-0.4	-0.5	0.1
Smoking status: Current	0.2	0.3	2.4	-0.5	-0.1	0.2	-0.1	-1.5	-0.7	0.2	0.7	-0.3	-0.2	-0.3	-0.2	0.2	-0.6	-0.3	0.3
Average weekly champagne plus white wine intake	0.2	0.3	1.6	-0.7	-0.0	-0.3	0.4	-0.7	-0.1	-0.1	1.1	-0.0	0.1	-1.3	-0.1	-0.1	-0.2	-0.4	0.9
Miserableness	0.2	0.3	1.6	-0.2	0.6	-0.4	-0.4	0.7	-0.3	-0.2	0.1	0.9	0.2	1.3	-0.0	0.9	0.1	0.8	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.0	0.4	0.2	0.0	-0.2	0.2	0.1	0.4	0.8	0.4	0.2	-0.8	0.3	0.9	0.1	0.2	1.0
Medication: Blood pressure	0.2	0.4	1.1	0.9	0.8	-0.5	-0.2	-0.7	0.6	-0.8	1.0	0.3	0.9	0.2	0.7	0.1	-0.1	0.0	0.8
Medication: Paracetamol	0.2	0.3	1.8	-0.2	-0.4	0.6	-0.4	0.5	-0.0	0.2	-1.4	-0.1	-0.5	0.8	-0.5	0.1	0.3	0.3	-0.1
Number of operations (self-reported)	0.2	0.3	2.7	-0.5	-0.3	0.2	0.4	0.3	-0.4	0.1	-1.6	-0.1	-0.3	0.1	-0.7	-0.0	-0.1	-0.1	-0.4
Average weekly beer plus cider intake	0.2	0.3	1.3	1.1	-0.2	0.3	0.2	1.1	-0.1	0.0	-0.2	0.6	-0.3	0.7	0.1	-0.6	-0.3	-0.1	-0.6
Irritability	0.2	0.3	1.2	-1.1	0.2	-0.8	-0.2	0.9	-0.3	0.0	-0.2	-0.1	0.3	-0.3	0.5	0.2	0.2	-0.6	0.8
Ever depressed for a whole week	0.2	0.2	1.7	-1.3	0.2	-0.2	0.1	-0.1	0.0	0.0	0.4	0.8	0.2	0.7	0.2	-0.1	-0.1	0.1	-0.6
Cholesterol lowering medication	0.2	0.3	1.1	-0.3	-0.3	0.6	0.1	-0.6	-0.6	0.8	-1.1	-0.9	-0.3	0.0	-0.4	-0.6	-0.8	-0.4	-0.5
Schizophrenia (2018)	0.1	0.2	1.2	-0.3	-0.1	0.2	-0.0	-0.4	-0.1	0.4	1.1	0.2	-0.1	-0.6	-0.2	0.5	-0.4	-0.1	1.1
Neuroticism (2016)	0.1	0.2	0.5	-0.4	0.2	-0.1	-0.4	-0.0	0.2	0.2	-0.6	0.6	-0.2	0.6	-0.3	0.7	0.4	0.7	0.3
Schizophrenia (2014)	0.1	0.3	1.2	0.3	-0.2	0.4	0.4	0.0	-0.4	0.6	0.2	-0.1	-0.3	-0.9	-0.4	0.1	-0.8	-0.8	1.1
Heel T-Score	0.1	0.5	2.4	-0.1	0.9	-0.9	-0.3	-0.6	0.0	-0.8	1.1	0.2	0.9	-0.3	0.5	0.4	-0.1	0.1	1.6
Respiratory disease	0.1	0.2	1.2	-0.5	-0.2	0.1	0.1	-0.5	-0.5	0.3	0.3	0.5	-0.0	1.1	0.0	-0.1	-0.7	-0.6	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.3	0.4	0.4	-0.4	-0.3	-0.1	0.1	-0.4	0.1	1.1	0.3	-0.5	0.4	0.4	0.4	0.0	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.4	0.3	-0.2	-0.1	0.4	-0.5	-0.1	-0.1	0.3	0.2	-0.1	-0.6	0.0	-0.0	-0.5	-0.6	0.1
Number of incorrect matches in round	0.1	0.2	1.6	0.2	-0.2	0.1	-0.1	-0.5	0.1	0.1	-0.4	0.0	-0.1	-0.7	-0.3	-0.8	-0.3	-0.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.7	-0.3	0.0	-0.4	-0.1	0.8	-0.3	0.0	-0.4	0.6	0.0	0.2	-0.1	0.1	0.2	0.0	0.7
Hair/balding pattern: Pattern 2	0.1	0.1	0.7	-0.6	0.2	0.0	0.0	0.6	0.1	-0.1	0.0	-0.8	-0.0	0.3	-0.5	-0.1	0.1	0.2	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.6	-0.7	-0.1	-0.1	0.1	-0.5	0.2	-0.2	0.7	0.6	-0.1	0.8	0.2	0.3	0.2	-0.0	-0.1
Asthma	0.1	0.2	0.5	-0.5	0.3	-0.1	-0.5	0.1	-0.1	-0.0	0.7	0.6	0.4	0.6	0.1	0.5	-0.1	0.1	0.6
Standing height	0.1	1.4	4.3	0.3	0.9	-0.9	-1.6	0.2	1.9	-1.2	-1.6	0.8	0.7	0.4	0.7	1.1	2.1	2.0	-0.2
Pulse wave reflection index	0.1	0.1	0.7	-0.8	0.3	0.1	-0.2	0.5	0.2	0.4	0.6	0.1	0.1	0.0	-0.1	0.1	-0.0	0.3	0.6
Blood clot in the leg (DVT)	0.1	0.1	0.4	0.2	0.0	-0.0	-0.1	0.7	0.3	-0.3	-0.3	-0.2	0.0	0.6	-0.1	0.4	0.2	0.3	-0.4
Migraine (self-reported)	0.1	0.2	1.3	-0.5	0.0	0.1	0.0	1.1	-0.2	0.0	-0.5	-0.3	-0.1	0.5	-0.6	-0.2	-0.2	0.3	0.2
Number of full sisters	0.1	0.1	0.8	-0.6	0.1	0.0	0.0	0.5	0.1	-0.3	0.9	0.3	0.1	0.3	0.1	0.4	0.1	-0.3	-0.1
Age at last live birth	0.1	0.1	0.4	0.1	-0.3	0.1	0.3	-0.1	0.2	0.0	0.5	0.3	-0.4	0.2	-0.1	0.0	-0.2	0.3	-0.6
Breast cancer (self-reported)	0.1	0.1	0.9	0.3	-0.2	0.1	0.1	0.9	-0.5	0.1	-0.2	-0.5	-0.3	0.6	-0.4	-0.1	-0.1	-0.2	0.2
Asthma (self-reported)	0.1	0.1	0.3	-0.4	0.2	-0.1	-0.3	0.0	-0.2	-0.0	0.6	0.4	0.4	0.5	0.1	0.2	-0.4	-0.1	0.5
Eye problems/disorders: Glaucoma	0.1	0.2	0.7	0.5	-0.2	0.1	0.3	0.6	0.1	0.3	-0.4	0.6	-0.1	0.7	0.3	0.3	-0.0	-0.2	-0.9
Medication: Lisinopril	0.1	0.2	1.0	1.0	0.5	-0.4	-0.1	-0.2	0.2	-0.4	0.2	-0.3	0.6	0.1	0.8	0.1	-0.1	-0.2	0.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	0.3	0.2	-0.2	-0.2	0.6	0.4	-0.6	-0.1	-0.1	0.2	0.4	0.1	0.5	0.3	0.2	-0.1
Blood Eosinophil Count	0.0	0.3	1.0	-0.3	0.0	-0.4	0.1	-0.6	0.1	-0.6	0.3	-0.2	0.4	-1.0	0.4	-0.6	-0.4	-0.9	0.5
Blood Red Count	0.0	0.3	1.0	0.2	0.5	-0.3	-0.2	0.7	-0.0	-0.2	-0.9	-0.3	0.6	0.3	0.3	-0.8	-0.2	-0.5	-1.0
Hair Pigment	0.0	0.8	2.9	-0.6	-0.8	0.2	1.1	-0.8	0.0	-0.1	1.2	-1.2	-0.4	-1.7	-0.4	-0.8	-0.8	-1.4	0.2
Tanning	0.0	0.2	1.9	-0.1	0.1	0.1	-0.0	-1.1	-0.2	0.2	-1.4	-0.3	-0.0	-0.2	-0.3	0.1	-0.3	-0.1	0.4
Medication: Paracetamol	0.0	0.1	0.2	-0.2	-0.3	0.4	-0.4	0.2	0.3	-0.1	-0.2	-0.2	-0.3	0.2	-0.2	0.1	0.3	0.1	0.4

Hub : Genes

CYB5A

Models

Trait associations