[Hub]/) : Traits : BMI : ← →

chr19:1,086,043-2,732,986

Best TWAS P=6.09e-14 · Best GWAS P=7.98e-14 conditioned to 0.000462

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REXO1 0.07 0.01 bslmm 391 0.01 1.7e-02 -5.3 7.5 6.1e-14 -0.51 0.12 0.57 TRUE
2 GTEx Adipose Visceral Omentum ATP8B3 0.23 0.01 enet 35 0.12 6.5e-07 -2.7 -5.7 1.4e-08 0.22 0.18 0.08 FALSE
3 GTEx Brain Cerebellum AC012615.1 0.36 0.11 lasso 4 0.04 3.3e-02 -5.8 -5.9 3.8e-09 0.11 0.07 0.44 TRUE
4 GTEx Esophagus Muscularis KLF16 0.17 0.07 enet 9 0.09 3.7e-06 -6.5 -6.5 8.3e-11 0.50 0.20 0.74 FALSE
5 GTEx Esophagus Muscularis BTBD2 0.17 0.07 lasso 4 0.09 4.5e-06 -5.0 -5.5 2.8e-08 0.05 0.70 0.04 FALSE
6 GTEx Esophagus Muscularis CTB-31O20.6 0.16 0.07 lasso 5 0.05 7.8e-04 -6.5 -6.6 4.6e-11 0.50 0.21 0.66 FALSE
7 GTEx Heart Atrial Appendage ATP8B3 0.24 0.12 lasso 3 0.10 2.3e-05 -5.6 -5.3 1.2e-07 0.57 0.14 0.18 FALSE
8 GTEx Lung ATP8B3 0.20 0.07 lasso 7 0.15 1.8e-11 -5.6 -5.3 1.4e-07 0.44 0.82 0.18 FALSE
9 GTEx Skin Sun Exposed Lower leg CTB-31O20.6 0.15 0.04 lasso 3 0.01 7.5e-02 -5.2 5.3 9.6e-08 -0.04 0.06 0.14 FALSE
10 GTEx Thyroid BTBD2 0.18 0.01 lasso 4 0.06 2.4e-05 -5.7 -5.1 2.8e-07 0.18 0.64 0.03 FALSE
11 ROSMAP Brain Pre-frontal Cortex KLF16 0.12 0.08 bslmm 372 0.08 1.0e-10 -7.5 -5.9 3.2e-09 0.85 0.00 1.00 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATP8B3 0.06 0.00 blup 49 0.03 2.7e-04 -2.1 -6.0 1.4e-09 0.54 0.06 0.18 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ATP8B3 0.04 0.01 blup 49 0.02 2.2e-03 -7.5 -6.7 2.6e-11 0.84 0.00 0.76 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma SCAMP4 0.04 0.00 blup 49 0.01 9.5e-03 -5.3 -5.8 7.2e-09 0.41 0.02 0.10 FALSE