Best TWAS P=2.28e-07 · Best GWAS P=3.69e-10 conditioned to 0.153
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | WDPCP | 0.15 | 0.05 | lasso | 4 | 0.03 | 3.0e-02 | 3.8 | 5.2 | 2.4e-07 | 0.64 | 0.34 | 0.36 | TRUE |
| 2 | GTEx | Thyroid | WDPCP | 0.07 | 0.03 | lasso | 6 | 0.06 | 2.1e-05 | 3.3 | 5.1 | 3.1e-07 | 0.50 | 0.37 | 0.59 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TMEM17 | 0.10 | 0.03 | lasso | 4 | 0.04 | 2.5e-05 | 4.4 | -5.2 | 2.3e-07 | -0.39 | 0.00 | 0.78 | TRUE |