TWAS hub - WDPCP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2260	0.0490	0.0e+00	0.291	NA	0.267	NA	0.291	4.4e-24	NA	6.6e-22	NA	4.6e-24
2	GTEx	Adipose Visceral Omentum	0.0940	0.0450	3.0e-03	0.050	NA	0.015	NA	0.065	1.4e-03	NA	5.5e-02	NA	2.8e-04
3	GTEx	Artery Aorta	0.1570	0.0620	5.8e-06	0.050	NA	0.060	NA	0.068	9.9e-04	NA	3.1e-04	NA	1.4e-04
4	GTEx	Artery Tibial	0.0763	0.0338	7.5e-04	0.016	NA	0.040	NA	0.039	1.7e-02	NA	4.0e-04	NA	4.6e-04
5	GTEx	Brain Cerebellum	0.1430	0.0630	2.9e-03	0.000	NA	0.001	NA	-0.001	3.1e-01	NA	3.1e-01	NA	3.4e-01
6	GTEx	Breast Mammary Tissue (Male)	0.1286	0.0719	2.2e-02	0.014	NA	-0.004	NA	0.028	1.5e-01	NA	4.2e-01	NA	7.4e-02
7	GTEx	Cells Transformed fibroblasts	0.1350	0.0540	1.8e-05	0.075	NA	0.073	NA	0.068	2.7e-06	NA	3.6e-06	NA	7.7e-06
8	GTEx	Colon Sigmoid	0.1480	0.0620	4.3e-04	0.055	NA	0.003	NA	0.030	5.3e-03	NA	2.4e-01	NA	3.0e-02
9	GTEx	Esophagus Mucosa	0.0560	0.0260	2.5e-03	0.035	NA	0.026	NA	0.036	2.2e-03	NA	6.8e-03	NA	1.7e-03
10	GTEx	Esophagus Muscularis	0.0860	0.0370	1.2e-04	0.091	NA	0.042	NA	0.056	3.8e-06	NA	1.4e-03	NA	2.5e-04
11	GTEx	Heart Left Ventricle	0.1069	0.0439	1.7e-04	0.090	NA	0.075	NA	0.074	1.6e-05	NA	7.8e-05	NA	9.1e-05
12	GTEx	Lung	0.1274	0.0398	1.9e-08	0.046	NA	0.094	NA	0.084	2.0e-04	NA	1.2e-07	NA	5.4e-07
13	GTEx	Nerve Tibial	0.0758	0.0326	2.1e-04	0.020	NA	0.049	NA	0.047	1.3e-02	NA	2.2e-04	NA	2.9e-04
14	GTEx	Pancreas	0.1340	0.0520	4.0e-04	0.061	NA	0.021	NA	0.036	1.5e-03	NA	4.3e-02	NA	1.2e-02
15	GTEx	Stomach	0.0750	0.0410	8.4e-03	0.035	NA	0.032	NA	0.023	8.9e-03	NA	1.1e-02	NA	2.7e-02
16	GTEx	Testis	0.1700	0.0700	3.9e-05	0.080	NA	0.123	NA	0.107	2.1e-04	NA	4.2e-06	NA	1.9e-05
17	GTEx	Thyroid	0.0710	0.0270	1.7e-05	0.028	NA	0.056	NA	0.060	2.8e-03	NA	3.9e-05	NA	2.1e-05
18	GTEx	Whole Blood	0.0490	0.0230	1.1e-03	0.042	NA	0.014	NA	0.032	8.5e-05	NA	1.8e-02	NA	5.4e-04
19	METSIM	Adipose	0.0999	0.0264	0.0e+00	0.116	0.152	0.145	0.15	0.139	6.6e-17	5.4e-22	4.9e-21	8.4e-22	3.8e-20

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Prostate Cancer	14.2	20.0	41.7	4.3	3.5	4.3	3.5	3.6	3.7	2.2	5.3	5.4	4.9	3.7	2.6	4.8	5.1	4.0	4.5	6.5	5.2	5.5
Ever unenthusiastic/disinterested for a whole week	8.3	10.2	13.6	3.4	3.1	3.5	2.7	3.3	1.1	2.4	3.0	3.7	3.2	3.4	2.4	3.7	3.0	3.5	3.4	3.5	3.5	3.7
Systolic Blood Pressure	6.7	33.8	51.1	-5.2	-5.3	-5.3	-6.6	-7.2	-4.1	-4.2	-5.8	-6.2	-5.8	-5.3	-5.5	-7.1	-5.4	-6.9	-5.3	-5.8	-5.2	-7.0
Commuting to job workplace: Public transport	6.7	8.0	13.6	2.8	2.9	2.2	3.1	2.4	2.9	2.9	3.2	3.1	2.6	2.6	3.7	1.9	3.1	2.9	2.5	2.9	2.8	2.8
Respiratory disease	6.3	14.0	19.8	4.4	4.3	4.5	2.6	3.8	1.6	2.5	4.4	4.5	3.5	3.0	2.4	3.8	4.1	3.8	4.3	4.2	3.2	4.4
Ever smoked	6.1	10.8	17.0	-3.9	-3.6	-3.2	-2.0	-1.8	-3.5	-2.5	-3.6	-3.4	-4.1	-4.1	-2.8	-2.3	-3.5	-3.3	-3.2	-3.4	-3.6	-3.6
Ever taken oral contraceptive pill	6.0	6.7	15.6	-2.5	-2.3	-2.8	-2.4	-2.3	0.0	-1.2	-3.2	-2.8	-2.7	-4.0	-1.5	-2.7	-2.5	-2.7	-2.8	-3.0	-2.8	-2.9
Past tobacco smoking	5.5	10.0	17.2	3.6	3.4	2.3	1.7	1.9	3.8	2.4	3.6	3.3	4.2	3.5	3.1	2.0	3.5	3.4	2.6	3.4	3.5	3.5
Birth weight	5.3	11.4	18.1	2.0	2.0	3.0	4.0	4.3	2.1	2.9	3.7	4.0	3.5	3.1	2.8	4.0	3.6	3.8	3.8	3.5	3.0	3.8
Financial situation satisfaction	5.2	6.4	13.2	2.3	2.1	2.3	2.5	3.6	0.7	2.6	2.3	2.5	2.3	1.7	2.9	3.6	2.3	3.2	2.8	2.6	1.8	2.4
Ever depressed for a whole week	5.1	6.3	12.5	2.5	2.3	2.6	2.0	2.2	1.1	0.6	2.7	2.7	3.3	3.5	2.4	2.6	2.3	2.6	2.5	2.7	1.9	3.1
Qualifications: NVQ or HND or HNC or equivalent	4.9	5.9	11.0	2.5	2.6	2.6	1.9	3.2	-1.1	1.8	3.3	2.1	1.2	2.5	2.6	2.6	1.9	2.7	2.9	2.8	1.3	2.9
Allergy	4.7	10.9	15.9	-3.4	-3.0	-3.4	-2.5	-3.5	-1.8	-2.1	-4.0	-3.4	-3.8	-2.8	-3.2	-3.2	-3.6	-3.9	-3.2	-3.8	-3.4	-3.8
Allergy or Eczema	4.5	11.8	21.1	3.6	3.0	3.6	2.5	3.3	2.1	2.8	3.6	4.1	3.5	2.9	3.2	3.8	4.1	3.5	3.2	3.2	4.6	3.9
Headache pain in last month	4.5	7.7	12.7	-3.0	-3.0	-3.5	-1.8	-1.9	-0.4	-2.9	-3.1	-2.9	-3.3	-3.1	-1.6	-2.2	-3.2	-2.9	-3.6	-2.8	-2.7	-3.0
Serious illness, injury or assault to yourself	4.4	5.3	11.5	2.1	2.1	1.9	2.3	2.7	1.1	2.8	3.4	1.8	2.7	2.2	3.2	1.4	1.9	3.0	2.1	2.4	1.2	1.7
Lung cancer (father)	4.4	5.1	9.6	-3.1	-2.7	-2.7	-1.1	-1.5	-1.5	-1.4	-2.9	-2.2	-2.8	-2.2	-2.2	-1.4	-2.5	-2.3	-2.6	-2.5	-1.1	-2.5
Medication for hormone replacement therapy	4.3	4.8	9.7	-2.7	-2.6	-2.6	-0.8	-1.0	-1.9	-2.7	-2.8	-2.1	-1.5	-2.4	-1.6	-1.5	-1.9	-2.2	-2.1	-2.2	-3.1	-2.4
Waist circumference	4.2	15.4	27.9	3.9	4.2	4.2	4.0	3.6	2.6	3.6	5.3	3.8	3.7	3.1	3.7	3.5	3.8	4.4	3.6	5.1	4.0	3.5
Rheumatoid Arthritis	4.1	5.7	15.4	2.1	1.5	1.3	1.7	2.2	1.9	0.9	3.0	2.8	3.9	2.9	2.0	1.8	2.8	3.0	1.4	2.9	2.5	2.5
Leg pain on walking	4.1	5.2	8.2	2.0	1.8	2.3	2.9	2.0	0.5	2.5	2.5	2.5	2.3	2.4	1.8	2.2	2.3	2.3	2.6	2.4	2.6	2.3
Bipolar Disorder (2011)	4.0	3.9	7.6	-2.2	-2.1	-2.1	-1.0	-1.8	-1.9	0.3	-2.1	-2.0	-2.5	-2.4	-1.7	-2.8	-1.8	-2.1	-1.2	-2.0	-1.6	-2.4
Body Mass Index (BMI) (2010)	3.9	5.4	9.6	2.3	2.4	3.0	1.9	1.6	0.2	1.3	3.1	2.6	2.4	2.8	1.1	1.6	2.3	2.6	2.6	2.6	2.7	2.9
Blood clot in the leg (DVT)	3.8	4.9	9.9	2.5	2.6	2.2	1.8	2.4	0.9	1.5	2.6	2.0	1.8	1.8	3.0	2.6	2.3	2.4	1.9	3.1	1.1	2.3
Medication: Ventolin 100micrograms inhaler	3.8	4.8	10.0	2.9	3.0	2.6	1.3	1.9	0.4	1.8	2.4	2.4	1.6	2.1	1.1	1.5	1.9	2.4	2.9	2.3	2.1	3.2
Risk taking	3.8	5.5	10.6	-2.3	-2.5	-1.6	-1.3	-1.8	-1.6	-2.1	-2.7	-2.3	-3.2	-3.3	-2.6	-1.5	-2.2	-2.9	-2.6	-1.8	-2.3	-2.8
Smoking Status	3.6	8.7	19.3	-2.9	-2.6	-1.7	-1.6	-1.2	-3.5	-2.5	-3.5	-3.4	-4.4	-3.4	-2.3	-1.5	-3.6	-2.8	-2.1	-3.4	-4.1	-3.1
Maternal smoking around birth	3.6	5.2	9.2	-2.8	-2.3	-1.4	-1.8	-1.3	-2.6	-0.9	-2.5	-2.7	-3.0	-2.1	-1.2	-1.3	-2.9	-2.3	-2.0	-3.0	-2.7	-2.9
Age started oral contraceptive pill	3.6	4.5	7.3	2.6	2.0	1.7	0.1	0.9	2.6	2.2	1.7	2.7	2.2	2.6	1.7	1.6	2.7	1.5	2.4	2.0	2.6	2.5
Hair/balding pattern: Pattern 2	3.5	4.4	7.4	2.3	2.1	1.9	1.3	1.2	2.4	1.5	2.1	2.5	2.4	1.3	1.5	2.4	2.6	1.7	2.3	2.7	2.2	2.6
Fed-up feelings	3.3	6.0	14.7	1.8	2.3	2.1	3.3	3.8	0.3	1.7	2.6	2.1	1.6	2.7	2.4	3.5	1.7	2.9	2.2	2.9	1.3	2.6
Hayfever, allergic rhinitis or eczema	3.3	7.1	14.3	2.7	2.2	2.8	2.0	2.4	1.3	2.1	3.0	2.9	3.2	2.3	2.6	2.5	3.0	3.0	2.5	2.6	3.8	3.0
Long-standing illness, disability or infirmity	3.3	5.1	8.5	2.2	2.2	2.5	2.7	2.6	1.2	1.5	2.9	2.4	1.4	2.1	1.5	2.9	2.1	2.1	2.7	2.7	2.0	2.2
Deep venous thrombosis (DVT) (self-reported)	3.3	4.2	8.2	2.3	2.6	1.9	1.7	2.4	0.8	1.5	2.2	1.6	1.4	1.6	2.8	2.6	2.0	2.3	1.9	2.9	0.8	2.1
Hip circumference	3.2	14.0	29.4	3.7	3.8	4.4	4.4	3.2	2.7	2.7	5.0	3.9	2.9	2.9	3.6	3.6	3.6	3.4	3.6	5.4	3.6	3.5
Medication: Amlodipine	3.2	4.4	11.1	-2.0	-2.1	-2.4	-1.4	-1.5	-0.4	-2.5	-1.9	-2.4	-1.8	-2.7	-1.4	-2.2	-2.5	-1.9	-2.3	-1.5	-3.3	-2.1
Age at first live birth	3.2	5.7	9.3	2.3	2.2	2.1	2.8	2.5	2.2	2.6	2.3	2.2	2.6	1.9	2.2	3.0	2.1	3.0	2.0	1.8	2.3	2.8
Smoking status: Previous	3.2	4.8	9.3	-2.6	-2.4	-0.7	-0.4	-1.2	-2.9	-2.0	-2.5	-2.0	-3.0	-2.4	-2.6	-0.9	-2.4	-2.5	-1.4	-2.2	-2.3	-2.3
Falls in the last year	3.1	4.3	8.1	1.9	2.3	1.9	2.5	2.3	0.6	1.0	2.1	1.8	2.6	1.9	1.6	2.8	1.1	2.6	2.6	2.7	0.6	2.3
HDL Cholesterol	3.0	4.9	8.4	-2.8	-2.9	-2.1	-1.9	-2.1	-1.8	-1.1	-2.0	-2.9	-2.6	-2.4	-2.5	-1.4	-2.4	-2.6	-1.7	-2.2	-1.7	-2.3
Health satisfaction	2.9	3.8	8.4	0.9	0.8	1.2	2.0	2.9	1.3	1.4	2.2	1.6	2.4	1.9	2.3	2.9	1.1	2.6	1.9	2.2	1.3	1.9
Qualifications: College or University degree	2.9	9.2	13.5	3.0	2.6	2.3	2.7	2.6	3.7	3.0	3.3	3.5	3.4	2.3	3.1	2.7	3.6	3.1	2.8	3.2	2.7	3.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.1	10.1	-2.6	-2.0	-2.5	-1.0	-2.1	-2.3	-2.6	-3.2	-2.9	-2.3	-2.6	-2.1	-2.3	-2.7	-2.6	-2.5	-2.6	-3.0	-2.1
Lung FVC	2.8	14.1	22.8	-4.2	-4.2	-3.7	-2.8	-2.9	-2.4	-2.1	-4.5	-4.3	-3.9	-4.2	-3.5	-3.8	-4.4	-3.6	-3.4	-4.8	-4.0	-3.5
Financial difficulties in last 2 years	2.7	3.6	10.7	1.2	1.6	1.5	3.1	3.3	0.3	2.0	1.5	1.5	0.7	1.3	1.9	2.8	1.3	2.1	2.1	2.6	0.5	1.5
Weight	2.7	13.3	25.4	3.4	3.4	4.4	4.4	3.4	2.7	2.7	4.9	3.7	3.4	2.8	3.6	3.4	3.5	3.7	3.2	5.0	3.5	3.1
Peak expiratory flow (PEF)	2.6	5.9	11.5	-2.5	-2.8	-2.1	-1.4	-2.1	-1.5	-1.2	-2.8	-2.9	-2.0	-3.4	-2.3	-2.3	-2.5	-2.6	-2.4	-2.7	-3.0	-2.6
Leg fat mass (right)	2.6	9.9	18.1	2.9	3.2	3.6	3.7	2.8	2.2	2.7	4.2	3.2	2.9	2.3	3.0	3.0	3.2	3.2	2.9	4.2	3.3	2.5
Wears glasses or contact lenses	2.6	3.0	4.7	2.1	1.9	1.8	1.8	1.4	0.7	2.1	2.1	1.5	1.6	1.7	1.2	1.2	1.7	2.1	1.7	1.8	2.2	1.6
Neuroticism (Nagel 2018)	2.5	5.9	16.8	1.6	1.6	2.1	3.0	3.6	0.4	1.2	1.9	2.9	1.5	2.7	2.8	4.1	2.3	2.4	2.3	2.3	1.8	2.7
LDL Cholesterol	2.5	3.9	12.2	2.4	2.3	2.4	1.0	0.5	-0.3	2.1	3.5	1.9	2.8	1.6	1.3	-0.1	2.0	2.1	2.4	2.0	1.4	2.1
BMI	2.5	14.6	26.7	4.0	4.2	4.1	4.5	3.1	3.0	3.0	5.2	3.5	3.6	3.0	3.8	3.3	3.7	4.0	3.3	5.1	3.4	3.6
Other serious medical condition/disability diagnosed by doctor	2.5	3.3	6.6	1.9	1.9	1.6	2.2	1.4	1.8	1.6	2.4	1.6	1.2	1.5	2.3	2.4	1.9	1.0	1.3	2.6	1.1	1.8
Angina	2.5	3.2	5.9	1.9	2.0	2.4	1.4	0.8	1.9	1.8	2.1	1.8	1.6	1.9	1.6	1.8	1.3	1.3	2.3	2.0	1.4	2.0
Shortness of breath walking on level ground	2.5	2.9	5.5	2.0	2.0	1.8	1.1	1.4	0.4	0.6	2.0	2.1	1.5	1.5	0.7	1.9	1.9	1.5	2.3	2.1	2.0	2.0
Whole body fat mass	2.5	10.3	18.8	3.2	3.4	3.7	3.5	2.6	2.1	2.8	4.3	3.3	2.9	2.6	2.8	2.7	3.4	3.3	2.8	4.2	3.8	2.6
Medication for cholesterol	2.5	3.7	7.1	1.9	1.7	2.2	2.2	1.9	1.6	1.9	1.2	2.2	1.1	1.7	1.4	2.4	1.8	2.0	2.2	0.9	2.7	2.4
Asthma (self-reported)	2.5	5.0	9.0	2.4	2.1	2.3	2.2	2.8	1.5	0.8	2.8	2.6	2.6	1.3	1.7	2.1	2.3	2.4	2.4	3.0	0.7	2.7
Depressed Affect (Nagel 2018)	2.4	5.0	11.7	1.5	1.9	1.8	3.2	3.4	0.3	0.9	2.2	2.1	1.2	2.7	2.6	3.4	1.9	2.3	2.2	2.6	0.6	2.5
Body mass index (BMI)	2.4	10.1	22.5	3.2	3.4	3.4	3.5	2.6	2.2	2.2	4.6	3.1	3.1	2.4	2.9	2.7	3.1	3.2	2.8	4.7	3.0	2.7
Arm fat-free mass (right)	2.4	12.2	23.9	2.8	2.5	4.3	4.7	3.8	2.6	2.4	4.6	3.5	3.1	2.6	3.5	3.9	2.9	3.4	3.6	4.9	2.2	3.2
Worry too long after embarrassment	2.4	4.1	13.1	1.3	1.2	1.5	3.1	2.6	1.5	1.6	1.4	2.4	0.9	1.7	2.2	3.6	2.0	1.4	1.6	1.9	2.2	2.2
Wheeze or whistling in the chest in last year	2.4	4.2	9.3	1.5	1.7	3.0	2.2	3.0	0.2	1.1	2.2	2.4	1.4	2.2	1.2	2.9	1.8	2.2	2.4	1.9	1.6	1.9
Arm predicted mass (right)	2.4	12.3	24.1	3.0	2.6	4.3	4.7	3.7	2.8	2.5	4.6	3.5	3.1	2.6	3.6	3.8	3.0	3.4	3.6	4.9	2.2	3.2
Arm fat-free mass (left)	2.4	12.2	24.4	3.0	2.7	4.4	4.5	3.8	2.4	2.2	4.7	3.4	3.0	2.6	3.5	3.8	2.9	3.5	3.4	4.9	2.3	3.2
Arm predicted mass (left)	2.4	12.0	24.1	2.9	2.6	4.2	4.6	3.9	2.6	2.4	4.6	3.4	2.9	2.6	3.5	3.9	2.9	3.5	3.3	4.9	2.3	3.0
Vitamin and mineral supplements	2.3	3.1	8.0	2.1	1.6	2.2	-0.6	0.4	0.0	0.1	2.3	2.0	2.8	2.8	-0.7	-0.0	1.8	2.1	2.0	1.8	1.6	1.8
Pack years adult smoking proportion	2.3	3.5	8.2	-1.7	-1.6	-1.9	-2.3	-1.9	-1.3	-0.8	-1.4	-2.4	-1.3	-1.3	-1.1	-2.9	-2.1	-1.4	-2.0	-2.3	-2.4	-2.3
Asthma	2.3	4.5	8.0	2.4	2.2	2.0	2.0	2.6	1.3	0.6	2.7	2.5	2.6	1.4	1.7	1.8	2.2	2.3	2.2	2.8	0.7	2.6
Loud music exposure frequency	2.3	2.5	5.7	1.8	1.9	2.4	1.6	1.5	0.5	1.4	2.1	1.6	1.6	1.1	1.6	1.1	1.4	1.9	1.6	1.6	1.3	1.4
Leg fat percentage (right)	2.3	8.3	14.0	3.0	3.4	3.2	2.6	2.3	2.0	2.9	3.7	2.9	2.2	2.4	2.7	2.7	3.0	2.8	2.8	3.6	3.4	2.2
Pulse wave peak to peak time	2.3	2.7	9.5	1.6	1.6	3.1	1.2	1.5	1.8	1.2	2.6	1.5	0.4	1.0	1.3	1.6	1.2	1.3	1.9	2.1	0.6	1.6
Leg fat mass (left)	2.3	8.9	17.5	2.9	3.1	3.4	3.4	2.7	1.9	2.4	4.2	3.0	2.7	2.2	2.8	2.7	3.0	3.1	2.7	4.2	3.1	2.4
Neuroticism	2.2	5.4	19.8	1.5	1.5	1.8	3.6	4.0	0.4	0.9	1.5	2.5	0.7	2.3	2.9	4.5	1.9	2.0	1.6	2.1	1.6	2.4
Trunk fat mass	2.2	9.4	16.2	3.1	3.3	3.6	3.2	2.4	2.3	2.9	4.0	3.0	2.6	2.4	2.8	2.5	3.1	3.2	2.5	4.0	3.8	2.4
Prospective memory result	2.2	2.7	5.0	1.8	1.6	1.3	1.9	1.7	0.6	0.4	1.7	1.7	1.7	1.8	1.4	2.2	1.6	1.8	1.4	2.0	1.7	1.9
Supplements: Calcium	2.2	2.4	6.9	-2.0	-2.1	-1.5	-1.6	-1.3	-0.0	-1.0	-2.2	-1.1	-1.9	-1.8	-0.4	-0.0	-1.0	-2.6	-1.4	-1.8	-1.0	-1.8
Worrier / anxious feelings	2.1	3.9	11.3	1.3	1.2	1.8	1.8	2.0	1.8	1.5	1.1	3.0	1.7	1.9	1.6	3.4	2.5	1.1	1.9	1.6	2.7	1.9
Heart disease (mother)	2.1	2.5	8.9	2.1	1.4	1.0	0.9	0.9	0.5	0.7	1.6	2.5	1.1	2.2	0.7	0.6	2.1	1.1	0.5	1.1	3.0	2.5
Back pain experienced in last month	2.1	3.0	10.2	0.7	0.7	1.6	2.6	3.1	1.5	1.1	1.2	1.4	0.9	1.1	2.5	3.2	1.1	1.6	1.7	1.6	-0.0	1.4
Basal metabolic rate	2.1	11.9	23.2	2.9	2.7	4.2	4.7	3.7	2.6	2.2	4.6	3.4	3.2	2.6	3.5	3.6	3.0	3.5	3.0	4.8	2.6	3.1
Pack years of smoking	2.1	3.1	7.7	-1.5	-1.3	-1.5	-2.2	-1.9	-1.5	-0.8	-1.3	-2.2	-1.2	-1.2	-1.2	-2.8	-1.9	-1.3	-1.7	-2.2	-2.2	-2.1
Fasting Glucose	2.0	2.4	4.5	-1.4	-1.5	-1.1	-1.5	-1.8	-1.3	-1.2	-1.9	-1.7	-1.4	-0.6	-1.5	-2.1	-1.7	-2.1	-1.7	-1.9	-1.0	-1.4
Frequency of depressed mood in last 2 weeks	2.0	2.8	9.5	0.4	0.6	1.1	2.9	3.1	1.0	1.5	1.2	1.2	0.1	1.1	2.1	3.0	0.7	1.4	2.3	1.7	-0.2	1.3
Depression (self-reported)	2.0	2.4	7.1	-2.7	-2.4	-2.3	1.2	1.1	-0.5	-1.6	-1.6	-1.1	-1.4	-1.3	-0.8	0.6	-1.9	-0.7	-2.2	-0.6	-1.4	-1.6
Arm fat mass (right)	2.0	8.1	17.0	2.8	3.1	3.2	3.2	2.3	2.0	2.3	4.0	2.7	2.7	2.2	2.7	2.4	2.8	2.9	2.3	4.1	3.0	2.2
Angina (self-reported)	2.0	2.6	5.1	1.6	1.8	2.2	1.2	0.7	1.9	1.6	1.9	1.6	1.5	1.7	1.5	1.6	1.1	1.1	2.1	1.7	1.2	1.8
Arm fat mass (left)	2.0	8.3	17.1	2.9	3.1	3.3	3.0	2.2	1.9	2.4	4.1	2.9	2.8	2.4	2.6	2.3	2.9	2.9	2.3	4.1	3.1	2.3
Medication: Blood pressure	2.0	3.8	8.6	-1.5	-1.6	-2.1	-2.9	-2.6	-1.5	-1.0	-1.5	-2.4	-1.4	-1.6	-1.2	-2.4	-1.9	-2.2	-1.8	-1.2	-2.0	-2.7
Depression (Nagel 2018)	1.9	2.8	9.8	0.8	0.9	1.9	2.3	2.6	0.2	1.1	1.4	1.4	0.6	1.6	1.4	3.1	0.9	1.4	2.6	1.8	-0.2	1.8
Trunk fat-free mass	1.9	10.9	23.0	2.5	2.2	4.2	4.8	3.9	2.2	1.9	4.3	3.4	2.9	2.6	3.4	3.9	2.7	3.3	3.2	4.4	1.8	3.2
Trunk predicted mass	1.9	11.0	23.2	2.5	2.1	4.2	4.8	4.0	2.2	1.9	4.3	3.4	2.9	2.6	3.4	4.0	2.7	3.3	3.2	4.4	1.8	3.2
Chest pain or discomfort	1.9	2.8	7.2	1.2	1.1	1.5	1.2	2.7	-0.8	2.2	2.4	1.6	0.8	1.6	1.2	1.3	1.2	2.4	2.0	1.3	1.4	1.9
Guilty feelings	1.9	2.9	8.9	0.7	0.6	1.6	2.3	1.9	1.5	2.1	1.3	2.1	0.7	1.4	1.7	3.0	1.5	1.0	1.7	1.6	2.5	1.1
Bipolar Disorder (2018)	1.8	2.9	5.1	-2.1	-2.1	-1.4	0.0	-1.6	-1.6	-1.1	-1.6	-1.6	-2.1	-1.6	-1.8	-1.5	-1.8	-2.1	-1.2	-1.3	-2.3	-2.0
Intelligence (Savage-Jansen 2018)	1.8	5.6	22.6	-1.6	-1.9	-3.0	-2.8	-3.7	0.3	-1.8	-2.3	-2.1	0.1	-1.5	-3.2	-4.8	-1.6	-1.8	-3.1	-2.1	-0.4	-1.7
Leg fat-free mass (left)	1.8	9.5	20.5	2.5	2.4	3.4	4.4	3.2	2.7	2.0	4.2	2.9	3.2	2.0	3.1	2.8	2.8	3.3	2.3	4.5	2.5	2.6
Current tobacco smoking	1.8	2.9	6.4	-1.2	-1.0	-1.7	-2.5	-1.0	-1.3	-1.7	-1.8	-2.2	-1.7	-1.8	-1.4	-1.6	-2.0	-0.9	-1.5	-1.8	-2.2	-1.6
Multivitamins +/- minerals	1.8	2.3	6.5	-2.3	-1.9	-1.6	0.7	-0.3	0.9	-0.0	-1.9	-1.4	-2.1	-2.5	0.8	0.6	-1.4	-2.0	-1.5	-1.7	-1.2	-1.3
Leg predicted mass (left)	1.8	9.7	20.6	2.5	2.4	3.5	4.4	3.2	2.7	2.0	4.2	3.0	3.2	2.1	3.2	2.9	2.9	3.4	2.3	4.5	2.5	2.7
Pain all over the body in last month	1.8	1.9	6.4	1.2	1.7	0.7	2.5	2.3	-0.1	0.3	1.1	0.8	0.5	1.1	1.5	2.2	0.7	1.5	1.2	1.4	-0.0	1.5
Forced expiratory volume in 1-second (FEV1)	1.8	6.0	12.9	-3.3	-3.2	-1.9	-1.1	-1.4	-1.4	-1.1	-3.1	-2.8	-2.1	-3.6	-2.0	-2.0	-2.6	-2.2	-2.5	-3.1	-2.5	-2.6
Happiness	1.8	2.2	5.2	1.5	1.4	0.9	1.7	1.9	0.9	0.1	1.0	1.6	1.7	1.4	1.9	2.3	1.5	1.6	1.4	1.2	1.4	1.6
Pulse wave Arterial Stiffness index	1.8	2.1	7.9	-1.5	-1.5	-2.8	-0.9	-1.1	-1.8	-0.9	-2.3	-1.3	-0.3	-0.8	-1.0	-1.3	-1.1	-1.1	-1.6	-1.9	-0.5	-1.4
Pulse wave reflection index	1.8	2.2	6.1	-1.4	-1.3	-2.5	-0.5	-0.3	-2.3	-1.6	-2.2	-1.4	-0.4	-1.9	-0.6	-1.1	-0.9	-0.8	-1.5	-1.9	-1.5	-1.2
Ever highly irritable/argumentative for 2 days	1.8	2.1	8.2	-1.9	-1.7	-1.2	-0.5	-0.2	-0.8	-1.3	-1.7	-1.9	-1.4	-1.0	-0.6	-0.2	-2.3	-1.1	-1.1	-1.0	-2.9	-1.6
Whole body fat-free mass	1.8	10.4	21.9	2.5	2.3	4.0	4.7	3.6	2.4	1.9	4.3	3.1	3.0	2.3	3.3	3.5	2.7	3.3	2.8	4.6	2.0	3.0
Whole body water mass	1.8	10.2	21.3	2.5	2.3	3.9	4.6	3.6	2.4	1.9	4.3	3.2	3.0	2.3	3.2	3.4	2.7	3.2	2.8	4.5	2.1	2.9
Tinnitus: Yes, now most or all of the time	1.8	2.1	7.5	1.1	1.0	0.9	2.7	2.2	1.8	1.5	0.7	1.4	0.4	0.9	1.5	2.4	1.1	1.1	1.2	1.4	1.3	0.9
Diastolic blood pressure, automated reading	1.8	5.5	12.4	-1.8	-1.4	-2.5	-3.0	-3.5	-0.9	-0.9	-2.9	-2.3	-2.4	-2.1	-1.9	-2.6	-1.8	-3.5	-1.5	-2.2	-1.7	-3.2
High blood pressure	1.7	4.6	12.0	-2.2	-2.1	-2.2	-2.1	-2.2	-1.7	-1.1	-2.0	-2.4	-1.2	-2.1	-2.1	-3.5	-1.8	-1.7	-1.7	-2.0	-2.4	-3.3
Medication: Cholesterol lowering	1.7	2.7	5.5	1.7	1.9	1.8	1.6	1.3	0.6	1.3	2.4	1.1	2.2	1.7	1.0	0.9	1.4	2.1	1.9	2.3	1.0	1.5
Length of working week for main job	1.7	1.9	5.9	1.2	0.9	1.9	-0.2	0.8	1.5	1.3	1.6	1.1	2.4	0.9	0.7	1.0	1.2	1.5	2.0	1.7	0.8	1.8
Body fat percentage	1.7	6.6	11.9	2.8	3.2	2.8	2.2	1.8	1.8	2.7	3.5	2.5	2.1	2.0	2.3	1.9	2.7	2.6	2.1	3.4	3.4	1.9
Comparative body size at age 10	1.7	4.8	18.1	2.7	2.6	1.5	0.6	0.2	4.3	0.1	1.4	1.9	4.0	2.0	1.9	2.2	2.2	1.4	1.3	2.9	1.7	1.6
Trunk fat percentage	1.6	6.4	13.2	2.7	3.1	2.8	2.1	1.7	1.9	2.8	3.2	2.4	2.0	2.0	2.2	1.8	2.7	2.7	1.9	3.3	3.6	1.8
Chronic bronchitis/emphysema (father)	1.6	1.9	4.1	1.8	1.9	1.3	0.3	1.2	-0.8	-0.4	1.6	1.1	1.9	2.0	0.6	0.2	1.1	2.0	0.9	2.0	0.8	1.6
Had other major operations	1.6	1.9	6.1	-0.7	-0.9	-0.8	-1.1	-1.0	-2.5	-1.3	-0.9	-1.4	-1.5	-0.9	-1.5	-1.9	-1.6	-1.3	-1.7	-1.5	-1.8	-0.8
Fluid intelligence score	1.6	3.3	12.7	-0.9	-1.2	-1.7	-1.8	-2.4	-0.6	-1.9	-1.6	-1.7	-1.1	-1.4	-2.5	-3.6	-1.5	-1.4	-2.3	-2.0	-1.3	-1.2
Neuroticism score	1.6	3.4	11.9	1.0	1.2	1.1	2.9	3.3	0.4	0.8	1.2	2.0	0.7	1.7	2.3	3.5	1.5	1.6	1.4	1.9	1.1	1.7
Handedness (chirality/laterality): Left-handed	1.6	1.9	5.8	-1.8	-1.3	-2.4	-0.2	0.3	-1.2	-1.3	-1.5	-1.7	-1.1	-1.2	-0.2	-0.9	-1.7	-0.3	-2.0	-1.3	-1.4	-1.7
Qualifications: nursing, teaching	1.6	2.5	7.2	1.2	1.2	1.5	2.7	1.9	0.6	0.5	1.4	1.9	1.9	1.7	1.6	1.6	1.9	1.5	1.4	1.3	0.5	2.0
Leg fat percentage (left)	1.6	5.8	11.6	2.6	2.9	2.7	2.2	1.9	1.4	2.2	3.4	2.4	1.8	1.9	2.1	2.1	2.4	2.4	2.3	3.3	2.8	1.9
Neuroticism (2016)	1.5	2.2	7.9	0.2	0.2	1.8	2.4	2.8	0.0	0.9	1.3	1.3	0.3	1.0	1.4	2.6	1.2	1.5	1.7	1.7	0.0	0.9
Systolic blood pressure, automated reading	1.5	4.3	10.0	-1.5	-1.5	-1.3	-3.1	-3.2	-2.4	-0.9	-1.6	-2.1	-2.3	-1.1	-2.3	-2.7	-1.9	-2.7	-0.8	-1.8	-1.2	-2.6
Severe depression (siblings)	1.5	1.7	6.7	0.5	0.5	1.2	2.4	2.0	0.3	0.6	1.2	1.2	0.8	0.1	1.6	2.6	1.0	0.9	1.2	1.5	0.6	1.0
Heart attack	1.5	1.9	4.7	2.2	2.1	1.5	-1.1	-0.7	1.7	0.6	1.7	0.8	1.9	1.4	0.3	-0.5	1.2	1.1	1.5	2.0	0.8	1.4
Impedance of arm (right)	1.5	7.0	15.3	-2.5	-2.2	-3.3	-3.7	-2.6	-2.0	-1.1	-3.8	-2.6	-2.2	-1.8	-2.4	-3.1	-1.9	-2.2	-3.2	-3.9	-0.9	-2.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	10.5	-2.7	-2.5	-1.7	-0.7	-1.1	-1.5	-1.1	-2.6	-2.6	-1.8	-3.2	-1.6	-2.0	-2.7	-1.8	-2.3	-2.4	-2.8	-2.0
Crohns Disease (2012)	1.4	2.3	4.0	1.4	1.7	2.0	1.4	1.7	-0.8	1.7	1.6	1.4	0.6	1.9	0.7	1.2	1.1	1.8	2.0	1.3	1.6	1.9
Medication: Metformin	1.4	1.9	4.7	-1.3	-1.0	-1.1	-1.1	-1.8	0.3	-2.2	-1.2	-1.7	-1.6	-1.2	-1.4	-0.4	-1.5	-1.8	-1.6	-0.3	-1.9	-1.4
Hearing difficulty/problems with background noise	1.4	2.3	6.9	1.2	1.3	1.9	2.1	2.1	1.0	1.2	1.5	1.4	0.5	1.1	1.3	2.6	1.2	1.4	1.4	1.7	0.5	1.7
Had major operations	1.4	1.6	4.7	0.1	0.1	1.1	1.2	2.2	0.1	1.5	2.1	1.2	0.9	1.1	0.6	1.4	1.2	1.9	1.1	0.9	1.7	1.2
Illnesses of siblings: Diabetes	1.4	1.7	3.6	1.3	1.2	1.1	0.3	1.2	1.9	1.6	1.0	1.6	0.7	0.8	0.9	1.7	1.4	1.4	1.7	1.2	1.5	1.4
Smoking status: Current	1.4	2.3	4.7	-1.2	-1.0	-1.6	-2.2	-0.5	-1.2	-1.4	-1.6	-2.0	-1.7	-1.7	-1.1	-1.4	-1.8	-0.6	-1.4	-1.6	-2.1	-1.4
Townsend deprivation index at recruitment	1.3	1.8	4.3	-1.5	-1.4	-2.1	-0.4	-0.9	-1.3	-1.5	-1.2	-1.2	-1.0	-0.6	-1.2	-2.0	-1.2	-0.7	-1.6	-1.5	-0.7	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	8.2	-0.2	0.2	0.9	2.2	2.9	-0.3	0.9	0.9	0.9	0.3	1.2	1.4	2.7	0.7	1.3	1.4	1.1	-0.4	0.8
Forced vital capacity (FVC)	1.3	5.1	10.8	-3.1	-3.3	-1.4	-0.9	-1.2	-1.8	-0.9	-2.8	-2.2	-2.1	-3.2	-2.2	-2.0	-2.3	-2.0	-1.9	-3.1	-1.7	-2.4
Medication: Simvastatin	1.3	2.0	4.3	1.5	1.6	1.6	0.6	1.0	0.0	1.3	2.1	1.2	1.9	1.5	0.3	0.4	1.7	2.0	1.5	1.9	1.0	1.1
Medication: Lansoprazole	1.3	1.5	3.8	-1.4	-1.2	-0.9	-1.1	-0.7	-1.3	-0.4	-1.1	-1.5	-1.4	-1.7	-0.6	-0.1	-2.0	-1.2	-0.5	-1.1	-1.6	-1.7
Impedance of arm (left)	1.3	6.0	13.7	-2.0	-1.8	-3.1	-3.7	-2.9	-1.8	-0.7	-3.5	-2.2	-1.9	-1.4	-2.3	-3.2	-1.6	-2.2	-2.7	-3.6	-0.6	-2.3
Knee pain experienced in last month	1.3	2.0	4.8	0.8	1.0	1.4	1.9	2.1	-0.3	1.6	1.7	0.9	0.7	0.6	1.8	2.2	0.3	1.6	1.6	1.8	0.1	1.1
Worry (Nagel 2018)	1.2	2.6	9.7	0.8	0.8	1.2	2.2	2.9	0.2	-0.0	0.9	1.8	1.4	1.7	1.8	3.1	1.2	1.7	1.4	1.3	1.2	1.8
Ever used hormone-replacement therapy (HRT)	1.2	1.5	2.6	-0.7	-1.1	-0.8	-0.9	-1.5	-1.5	-1.6	-1.5	-0.9	-1.3	-0.0	-1.5	-1.6	-1.2	-1.6	-0.5	-1.2	-1.6	-1.0
Mouth/teeth dental problems	1.2	1.9	6.4	1.3	0.8	1.0	0.8	0.2	2.2	0.9	1.1	1.8	2.5	1.2	1.1	0.2	1.9	1.0	1.3	1.0	1.9	1.5
Pulse rate	1.2	2.1	4.4	-1.8	-1.8	-1.3	-1.2	-1.0	0.7	-1.3	-2.1	-1.1	-1.4	-1.7	-1.4	-0.1	-1.5	-1.9	-1.1	-1.6	-1.3	-1.6
Tense / ‘highly strung’	1.2	2.0	6.9	-2.6	-2.3	-1.5	1.1	1.6	-1.3	-2.0	-1.2	-0.6	-1.4	-1.2	-0.8	0.9	-1.4	-0.6	-0.9	-0.5	-1.4	-1.4
Gout (self-reported)	1.2	1.7	5.9	-1.1	-0.8	-0.5	-0.2	-1.1	-2.4	-1.6	-1.2	-1.2	-1.7	-1.5	-1.2	-1.3	-1.2	-1.4	-1.1	-1.1	-0.8	-1.6
Medication: Allopurinol	1.2	1.5	3.7	-1.1	-1.0	-0.7	-0.1	-1.4	-1.4	-1.1	-1.2	-1.4	-1.6	-1.4	-1.0	-1.6	-1.2	-1.5	-1.1	-0.9	-0.6	-1.9
Pulse rate, automated reading	1.2	3.7	7.5	-1.9	-1.6	-2.3	-1.1	-1.1	0.0	-2.5	-2.7	-1.7	-1.8	-2.6	-1.2	-1.4	-1.7	-2.4	-2.2	-1.8	-2.4	-2.2
Supplements: Vitamin C	1.2	1.4	4.6	-0.9	-0.5	-2.1	0.7	-0.4	0.2	-1.3	-1.7	-1.2	-1.5	-1.2	0.9	-0.3	-0.7	-1.4	-1.7	-0.7	-1.5	-1.1
Hypertension (Self-reported)	1.2	3.4	9.0	-1.8	-1.8	-1.8	-1.7	-1.9	-1.1	-0.8	-1.7	-2.0	-1.2	-1.8	-1.5	-2.9	-1.4	-1.6	-1.5	-1.6	-2.1	-3.0
Leg fat-free mass (right)	1.2	6.5	16.0	2.0	1.9	2.9	3.9	2.6	2.3	1.3	3.6	2.3	2.7	1.6	2.5	2.2	2.2	2.8	1.7	4.0	1.9	2.1
Leg predicted mass (right)	1.2	6.3	15.7	1.9	1.8	2.8	3.8	2.6	2.3	1.3	3.6	2.3	2.7	1.5	2.5	2.1	2.1	2.7	1.6	4.0	1.9	2.1
Average weekly beer plus cider intake	1.2	1.7	9.9	-1.2	-0.4	-0.3	-0.6	-0.4	-3.1	-0.4	-1.5	-1.6	-2.1	-1.1	-1.3	-1.1	-1.3	-0.7	-1.0	-1.4	-0.9	-1.3
Triglycerides	1.1	1.8	2.9	1.7	1.7	1.5	1.3	1.3	1.2	1.0	1.5	1.4	0.7	1.7	1.4	0.9	1.1	1.6	1.1	1.5	1.3	1.4
Blood Eosinophil Count	1.1	8.7	14.9	3.6	3.6	3.0	1.7	3.2	1.4	2.4	3.4	2.5	3.4	2.8	3.1	2.6	2.5	3.9	2.6	3.5	2.1	3.3
Average weekly spirits intake	1.1	1.3	6.2	-1.0	-0.7	-1.5	-1.4	-0.5	-2.5	-1.1	-1.0	-0.8	-1.2	-0.8	-1.3	-1.3	-0.9	-0.4	-0.8	-1.4	0.4	-0.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.9	-1.0	-1.0	-1.0	-1.7	-1.0	-0.4	-0.9	-1.3	-0.8	-1.3	-1.7	-1.0	-1.7	-0.6	-1.0	-1.1	-0.9	-0.6	-1.2
Supplements: Glucosamine	1.1	1.5	3.5	-1.6	-1.4	-1.6	-0.5	-1.2	-0.5	-0.3	-1.9	-1.2	-1.1	-1.1	-0.5	-0.4	-0.9	-1.7	-1.4	-1.6	-1.0	-1.5
Overall health rating	1.1	2.3	10.2	0.3	0.5	1.0	1.9	3.2	0.4	1.1	2.3	1.0	0.7	0.7	2.0	1.9	0.4	2.3	1.4	1.9	0.6	0.9
Arm fat percentage (left)	1.1	4.6	10.2	2.3	2.7	2.2	2.0	1.2	1.4	2.0	3.2	2.0	2.2	1.6	1.9	1.2	2.3	2.1	1.4	3.1	2.9	1.5
Loneliness, isolation	1.1	1.6	4.8	0.8	1.1	0.8	2.2	2.1	0.1	0.7	1.1	1.1	0.4	1.0	1.4	1.8	1.1	1.4	1.2	1.1	1.1	1.1
Illnesses of father: None of the above (group 1)	1.1	1.3	3.3	-1.8	-1.4	-0.4	1.2	0.6	-0.6	-0.4	-1.0	-1.1	-1.6	-1.6	0.7	1.0	-1.8	-0.8	-0.6	-1.0	-1.6	-0.7
High cholesterol (Self-reported)	1.1	2.0	5.4	1.9	1.9	1.6	-0.4	-0.1	0.5	1.5	2.3	1.3	1.4	2.0	0.8	0.0	1.6	1.1	1.0	1.7	1.8	0.9
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.6	1.9	1.8	1.4	-1.3	-1.0	1.5	0.3	1.5	0.5	1.5	1.1	0.2	-0.7	0.9	0.7	1.2	1.7	0.4	1.1
Alcohol drinker status: Previous	1.1	1.3	6.5	-0.1	-0.3	0.5	2.1	1.1	2.5	0.6	0.3	1.0	-0.7	0.5	1.1	2.5	0.4	-0.1	0.6	0.8	1.1	0.1
Hair Pigment	1.0	27.8	49.8	5.3	5.2	4.8	4.3	6.4	2.2	6.3	6.0	5.2	4.8	4.6	5.2	4.4	5.4	7.1	5.5	5.4	5.5	4.9
Illnesses of siblings	1.0	1.4	4.0	-1.9	-1.7	-1.6	0.6	0.3	0.2	-0.8	-1.1	-1.4	-0.3	-2.0	0.2	-0.9	-1.4	-0.3	-1.6	-0.6	-1.5	-1.1
Arm fat percentage (right)	1.0	3.9	9.3	2.0	2.5	2.0	1.9	1.2	1.3	1.8	3.0	1.7	2.0	1.4	1.8	1.2	2.0	2.1	1.1	3.0	2.6	1.2
Neck or shoulder pain in last month	1.0	1.4	4.0	-1.3	-1.6	-0.6	-1.3	-1.0	-0.4	-1.8	-0.9	-1.6	-0.6	-0.4	-1.3	-0.9	-2.0	-1.1	-1.0	-1.1	-1.4	-0.9
Alcohol intake frequency.	1.0	2.4	6.5	1.1	1.0	1.9	1.3	0.6	2.5	-0.1	2.1	1.7	1.6	2.5	1.5	1.8	1.1	0.9	1.2	1.5	1.7	1.1
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	5.8	-0.5	-0.7	-0.3	-2.4	-2.1	0.8	-1.1	-1.4	-0.3	-0.2	-0.2	-1.9	-0.8	-0.4	-1.3	-0.7	-1.5	0.7	-0.2
Illnesses of father: Heart disease	1.0	1.4	6.2	1.0	0.4	-0.2	-2.5	-2.5	2.1	-0.2	0.3	0.2	1.1	0.3	-1.2	-2.0	0.8	-1.0	-0.0	0.4	0.5	0.1
Friendships satisfaction	1.0	1.2	3.3	1.3	1.3	0.7	0.4	1.1	0.1	-0.2	1.2	1.0	1.8	0.7	1.4	1.1	1.0	1.3	0.6	1.0	1.5	1.3
Eye problems/disorders: Cataract	1.0	1.1	3.1	0.8	1.1	1.5	1.1	0.4	0.9	0.1	1.1	0.9	0.7	1.7	0.1	1.8	0.6	0.3	1.1	1.6	0.6	1.0
Number of operations (self-reported)	1.0	1.5	2.6	-1.6	-1.5	-1.4	-1.0	-0.5	-1.6	-0.8	-0.7	-1.1	-1.4	-1.1	-1.5	-1.1	-1.3	-1.0	-1.4	-1.4	-1.2	-1.3
Impedance of whole body	1.0	5.2	13.2	-1.9	-1.8	-2.6	-3.5	-2.4	-1.7	-0.3	-3.6	-2.0	-2.4	-1.3	-2.1	-2.4	-1.6	-2.2	-1.9	-3.6	-0.8	-2.2
Verbal and Numeric Reasoning (VNR)	0.9	2.3	12.5	-0.8	-0.8	-1.2	-1.4	-2.6	0.1	-1.6	-1.0	-1.4	0.3	-0.7	-2.1	-3.5	-1.1	-0.9	-1.9	-1.3	-0.3	-0.9
Age when periods started (menarche)	0.9	2.2	4.8	2.0	2.0	1.6	-1.1	0.5	-0.6	1.4	1.8	1.5	1.8	2.2	0.7	0.4	1.5	1.6	1.8	0.6	1.4	2.0
Medication: Ibuprofen	0.9	1.1	4.4	-0.7	-0.6	-1.1	0.8	0.7	0.3	0.6	-0.5	-1.4	-1.4	-2.1	0.9	0.8	-1.0	-0.2	-1.1	-0.4	-1.7	-1.0
Heart disease (siblings)	0.9	1.2	4.1	1.6	1.2	1.9	-0.4	-1.1	0.6	0.8	1.1	1.2	0.4	2.0	-0.0	0.7	1.0	-0.4	1.0	0.3	1.2	1.0
Lung FEV1/FVC ratio	0.8	4.0	13.2	-1.4	-0.6	-1.6	-1.1	-1.9	0.1	-2.5	-2.9	-2.9	-1.6	-2.4	-0.9	-0.7	-2.3	-2.0	-2.2	-1.8	-3.6	-1.6
Tanning	0.8	9.9	17.7	-4.2	-3.7	-2.9	-1.7	-1.3	-4.0	-3.5	-3.0	-3.3	-2.1	-2.8	-3.8	-3.2	-3.7	-1.9	-2.6	-3.9	-3.1	-3.2
Exposure to tobacco smoke outside home	0.8	1.0	4.7	-1.0	-0.9	-0.7	-0.2	-0.2	0.0	-2.2	-1.1	-0.8	-1.1	-1.4	-0.2	-0.1	-1.0	-1.3	-0.1	-0.5	-1.9	-1.0
Hearing aid user	0.8	0.9	2.0	1.1	0.8	0.9	1.3	0.9	0.4	0.6	1.2	1.0	1.4	0.9	1.2	0.8	1.1	0.8	0.7	0.5	0.4	1.3
Vascular/heart problems diagnosed by doctor	0.8	2.1	9.5	1.2	1.2	1.3	1.6	1.9	1.1	0.6	0.9	1.7	0.4	1.1	1.3	3.1	1.1	0.9	0.9	1.1	1.6	2.3
Ovarian Cancer	0.7	0.9	2.5	1.4	1.4	0.8	0.7	1.3	-0.9	-0.2	1.0	1.0	0.7	0.7	0.5	0.5	0.7	1.4	0.5	0.6	1.1	1.6
Coronary Artery Disease (CAD)	0.7	0.8	3.0	-0.3	-0.5	0.0	-1.4	-1.6	-1.2	-0.3	-1.0	-0.1	-1.0	-0.3	-1.7	-1.2	-0.2	-1.0	-0.0	-1.0	-0.0	-0.7
Waist Hip Ratio (WHR)	0.7	3.3	11.8	1.9	2.3	1.1	0.1	2.0	1.0	3.4	1.9	1.6	1.5	1.2	2.5	1.4	1.9	2.5	1.1	1.0	2.1	1.3
Sensitivity / hurt feelings	0.7	1.1	2.8	1.3	1.0	1.1	0.8	0.8	0.2	0.6	1.3	1.4	0.7	1.7	1.6	1.1	1.2	0.6	0.5	0.8	1.3	1.1
Impedance of leg (left)	0.7	3.6	10.4	-1.7	-1.5	-1.9	-2.8	-1.5	-1.8	-0.4	-3.1	-1.5	-2.5	-0.9	-1.5	-1.2	-1.4	-2.1	-1.0	-3.2	-1.2	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	8.3	-0.8	-0.9	-0.1	1.9	2.9	-0.6	-0.1	0.6	0.8	0.0	0.5	0.9	1.9	0.1	0.8	0.6	0.4	-0.7	0.4
Qualifications: None of the above	0.7	1.5	6.2	-1.6	-1.1	-0.9	-0.4	-0.2	-2.5	-0.7	-1.2	-1.2	-1.7	-1.0	-1.6	-0.8	-1.5	-0.7	-1.1	-1.2	-0.5	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.4	-0.4	-0.7	-0.2	-1.8	-1.7	0.2	0.6	0.1	-0.9	-0.5	-0.7	0.4	-1.4	-0.8	-1.2	-0.1	-0.5	-1.0	-0.7
Mouth/teeth dental problems: Dentures	0.7	1.1	2.7	-0.4	0.0	-0.4	-1.2	-1.2	-1.2	-1.4	-0.8	-1.4	-1.6	-0.5	-0.8	-0.9	-1.3	-1.1	-1.0	-0.7	-1.3	-1.2
Medication: Aspirin	0.7	1.0	2.1	1.2	1.4	0.7	0.7	0.9	0.1	0.4	1.5	0.8	0.9	1.2	1.4	0.3	1.1	1.0	1.1	1.4	0.2	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	4.5	-0.0	0.4	-0.7	1.2	2.1	-0.9	0.6	0.2	-0.6	0.0	-0.7	1.4	-0.0	-0.7	1.6	0.1	0.3	-1.6	0.1
Medication: Aspirin	0.7	1.0	2.3	1.2	1.5	0.5	0.8	1.0	0.2	0.4	1.4	0.6	0.8	1.2	1.4	0.4	0.9	1.1	0.9	1.5	0.1	0.9
Miserableness	0.7	1.2	3.4	0.7	0.8	0.8	1.8	1.7	-0.0	-0.7	1.1	1.2	0.4	1.3	1.3	1.3	0.8	0.7	0.6	1.5	-0.1	1.5
Medication: Bendroflumethiazide	0.7	1.0	4.0	-0.3	-0.1	-1.1	-1.6	-1.3	-1.3	0.3	-0.8	-1.3	-0.6	-0.6	-0.4	-2.0	-0.5	-0.4	-0.3	-1.0	-0.9	-1.5
Medication: Paracetamol	0.7	1.0	1.9	-0.9	-0.8	-1.0	-0.2	-0.9	1.3	-0.1	-1.2	-1.4	-1.0	-1.4	0.5	-0.4	-1.3	-1.2	-1.1	-0.8	-1.3	-1.0
Alzheimer’s Disease (including proxy)	0.6	0.9	2.8	-0.6	-0.3	-1.0	-0.7	-0.2	-1.4	-1.3	-0.6	-1.1	-0.4	-0.8	-0.7	-1.7	-1.2	0.1	-1.4	-1.0	-0.9	-0.7
Crohns Disease (2017)	0.6	1.4	4.1	0.7	1.1	1.0	0.5	1.6	-0.7	2.0	1.0	1.3	0.0	1.2	0.6	1.4	0.9	1.1	1.8	1.3	1.4	1.0
Chronotype (morning person)	0.6	1.3	5.2	0.4	0.2	1.4	0.8	1.4	2.3	0.5	0.2	1.4	1.0	-0.9	1.3	2.3	1.0	0.2	1.3	1.3	-0.5	0.5
Supplements: Zinc	0.6	0.7	2.1	-0.9	-0.7	-1.0	0.6	-0.1	0.2	-0.5	-1.1	-0.6	-1.5	-1.3	0.2	0.4	-0.7	-1.2	-0.9	-0.8	-0.7	-0.7
Average weekly fortified wine intake	0.6	0.7	2.1	-0.6	-0.6	-1.4	0.6	-0.7	1.0	-0.5	-1.0	-0.5	-0.5	-1.3	-0.1	-0.7	-0.0	-1.1	-1.2	-0.5	-1.1	-0.1
Medication: Levothyroxine sodium	0.6	1.1	3.1	1.3	1.8	0.6	1.1	1.1	0.3	-1.6	0.1	1.3	1.0	0.6	0.9	1.0	1.3	0.3	0.5	1.2	-0.5	1.3
High blood pressure (mother)	0.6	0.8	2.5	-0.7	-0.7	-1.5	0.1	-1.2	0.5	-0.6	-0.8	-0.6	-0.6	-1.0	0.3	-0.3	-0.8	-1.6	-0.7	-0.4	-1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.6	0.9	3.9	0.5	0.2	1.1	0.8	0.6	2.0	-0.5	0.9	1.2	1.1	1.0	0.6	0.4	0.9	0.5	0.6	0.5	1.6	0.7
Noisy workplace	0.6	0.7	1.7	0.5	0.7	1.3	0.7	1.2	-0.4	1.1	1.3	0.6	0.6	0.8	1.2	0.4	0.5	1.0	0.6	1.2	0.7	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.1	-0.4	-0.2	-0.5	1.2	1.1	0.5	0.6	-0.0	-0.9	-1.2	-1.8	1.4	1.1	-0.6	0.1	-0.5	-0.0	-1.3	-0.6
Medication: Paracetamol	0.6	1.0	2.2	-1.3	-1.1	-1.3	0.4	0.0	0.5	0.1	-1.1	-1.4	-1.5	-1.4	0.3	-0.2	-1.4	-0.8	-1.1	-0.8	-1.2	-0.9
Breast cancer (self-reported)	0.6	0.7	1.4	-1.1	-1.2	-0.4	0.4	-0.8	1.1	-0.3	-1.0	-0.8	-0.7	-1.2	-0.2	-0.6	-0.6	-1.1	-0.7	-0.3	-0.8	-1.1
Average weekly champagne plus white wine intake	0.6	0.8	6.1	-0.4	-0.5	-1.2	0.8	0.1	2.5	0.6	-1.1	-0.3	-0.4	-1.8	0.8	0.4	0.2	-0.6	-0.4	-0.2	-0.4	-0.6
Pain type(s) experienced in last month: Hip pain	0.6	0.8	4.7	-0.6	-0.2	0.8	2.2	1.6	0.4	-1.2	-0.4	0.2	-1.0	-0.2	-0.0	1.7	-0.4	0.0	-0.2	0.3	-0.8	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	3.2	-1.1	-0.6	-0.6	1.8	0.1	-0.2	-1.0	-0.5	-0.6	0.0	-1.2	0.2	-0.1	-1.0	-0.5	-1.2	0.3	-1.0	-1.1
Pain experienced in last month	0.6	0.9	4.2	0.5	0.4	0.6	-0.9	-1.2	-1.3	0.4	0.5	0.9	1.0	0.5	-1.4	-1.6	1.0	0.1	0.4	-0.8	2.0	-0.1
Alzheimer’s Disease (in mother)	0.5	0.6	2.0	-0.4	-0.3	-0.4	-1.3	-0.4	-1.0	-0.9	-0.1	-1.0	-0.2	-0.3	-0.9	-1.4	-1.0	0.1	-0.8	-0.8	-0.5	-0.5
Lupus	0.5	0.7	2.9	1.0	1.1	0.7	0.2	-0.1	0.1	0.6	0.8	0.6	1.7	1.0	0.5	-0.8	0.7	1.3	0.8	0.8	1.1	0.3
Blood Platelet Count	0.5	6.3	13.2	3.1	3.3	2.1	0.3	2.5	-0.4	1.7	3.6	1.8	2.6	2.9	2.3	1.9	1.8	3.4	2.3	3.4	1.2	3.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.9	1.2	1.4	0.4	0.4	0.6	-0.2	0.6	0.6	0.5	0.3	0.4	0.2	1.0	0.7	0.7	0.8	1.3	0.5	0.9
Stomach or abdominal pain in last month	0.5	0.6	2.2	-0.8	-0.9	1.1	0.3	1.5	-0.7	1.2	0.1	0.8	-0.7	-0.5	0.5	1.1	-0.0	0.3	1.1	-0.7	-0.1	0.0
Time employed in main current job	0.5	0.6	2.8	0.5	0.5	0.5	0.0	0.6	0.3	1.5	1.2	0.8	0.5	0.3	0.6	0.2	0.8	0.7	0.3	0.5	1.7	0.3
Hair/balding pattern: Pattern 3	0.5	0.8	2.7	-1.1	-0.9	-1.4	0.0	0.1	0.0	0.2	-0.5	-1.2	-0.4	-0.7	0.3	-0.8	-1.4	0.1	-1.6	-1.4	-0.4	-1.1
Breastfed as a baby	0.5	0.6	2.8	0.8	0.4	-0.1	1.3	-0.5	1.7	0.7	0.7	-0.1	1.2	0.6	0.6	-0.9	0.2	0.9	-0.0	1.0	0.5	0.5
Hair/balding pattern: Pattern 4	0.5	1.2	3.4	1.8	1.7	0.6	-1.0	-0.6	0.7	1.0	1.4	0.2	1.2	1.5	1.6	-1.2	0.9	1.0	0.6	0.7	-0.2	0.3
Forced vital capacity (FVC), Best measure	0.5	1.9	6.2	-1.9	-2.0	-0.7	-0.2	-0.1	-1.3	-0.3	-1.6	-1.6	-1.1	-2.5	-0.9	-1.1	-1.7	-0.8	-1.2	-1.7	-1.6	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.4	-1.6	-1.5	-1.2	0.1	1.0	-0.3	-0.8	-0.4	-0.2	-0.5	-0.7	-0.5	0.5	-0.9	-0.4	-0.4	-0.2	-1.2	-0.6
Mouth/teeth dental problems: Loose teeth	0.5	0.5	3.3	-0.6	-0.5	-1.1	0.6	0.6	-1.8	-0.1	-0.3	-0.6	-0.1	-0.5	-0.1	-1.0	-0.5	0.3	-0.7	-0.7	-1.0	-0.6
Migraine (self-reported)	0.5	0.6	5.5	-0.1	-0.2	0.4	0.1	-1.2	0.3	-2.3	-0.3	-0.3	-0.3	0.0	-0.3	-0.3	-0.1	-1.3	-0.5	-0.7	-1.0	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	2.0	-1.0	-1.3	0.6	0.1	-0.7	0.1	-0.8	-0.5	0.0	-0.9	0.0	-1.4	0.2	-0.3	-1.2	0.4	-0.7	-0.6	-0.5
Suffer from ‘nerves’	0.5	0.7	4.4	-0.2	-0.1	-0.1	2.1	1.6	0.1	-0.7	0.2	0.6	0.8	0.9	0.8	1.4	0.1	0.9	-0.1	0.2	0.4	0.6
Mother’s age at death	0.5	0.6	1.8	-0.3	-0.5	-1.1	-0.5	-1.1	0.1	-0.8	-1.1	-0.7	-0.9	-0.8	-0.2	-0.3	-0.5	-1.3	-1.0	-0.6	-0.8	-0.4
Unable to work because of sickness or disability	0.5	0.6	1.4	-0.9	-0.8	-0.9	-0.4	0.2	-0.3	-1.0	-1.1	-0.7	-1.0	-0.2	-0.4	0.6	-1.2	-0.7	-0.6	-0.9	-1.2	-0.7
Bipolar Disorder or Schizophrenia	0.4	0.9	3.3	-1.0	-0.8	-0.9	0.9	-0.4	0.3	-0.5	-0.8	-0.7	-1.1	-1.8	0.3	0.3	-0.7	-1.3	0.1	-0.5	-1.6	-1.2
Schizophrenia (2018)	0.4	0.8	3.4	0.4	0.6	-0.0	1.1	0.7	1.8	0.3	0.2	0.4	0.2	-0.7	1.8	1.7	0.5	-0.0	1.2	0.3	-0.2	0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.4	0.9	1.2	0.3	-0.2	0.9	1.1	0.5	0.5	0.4	0.2	0.2	1.0	1.1	0.2	0.6	0.9	0.4	-0.3	1.0
Mean Putamen Volume	0.4	0.4	3.4	-0.5	-0.7	-0.1	0.1	-1.1	1.9	-0.0	-0.6	0.2	-0.3	0.4	-0.0	0.4	0.1	-1.3	0.0	-0.4	0.4	-0.5
Height	0.4	8.2	17.6	2.8	2.3	4.2	3.4	3.1	1.2	3.2	2.4	3.3	1.9	2.8	3.2	2.4	2.6	3.0	3.2	2.4	2.7	3.0
Cardiovascular Disease	0.4	1.3	7.8	-0.8	-0.6	-1.0	-1.6	-1.3	-0.9	0.6	-0.2	-1.3	0.4	-0.7	-0.6	-2.8	-0.5	-0.2	-0.9	-0.8	-1.0	-1.8
Hearing difficulty/problems: Yes	0.4	0.6	2.0	1.1	1.1	1.4	1.0	0.5	0.3	0.2	0.7	0.7	-0.3	0.4	0.4	1.0	0.8	0.4	0.6	0.7	0.7	0.9
Diabetes (father)	0.4	0.5	2.2	-1.2	-1.5	-1.1	-0.4	-0.3	-0.1	-0.3	-0.3	-0.1	0.0	-0.7	-0.9	-0.7	-0.6	-0.1	-0.6	-1.1	-0.1	-0.8
Diabetes (mother)	0.4	0.5	2.0	-1.2	-1.3	0.1	1.1	0.6	-1.4	-0.8	-0.1	-0.1	-0.2	0.4	-0.3	0.1	-0.7	-0.4	-0.4	0.1	-0.6	-0.7
Qualifications: CSEs or equivalent	0.4	0.5	1.5	0.0	0.3	0.7	-0.1	1.0	0.7	0.3	0.7	-0.0	-0.3	-0.4	0.7	1.2	0.1	0.3	1.1	1.2	-1.1	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.8	-1.3	-0.8	-0.3	0.3	0.4	-0.3	-0.5	-0.3	-0.7	-0.3	-1.3	-0.1	0.2	-1.0	-0.1	0.1	-0.8	-1.3	-0.5
Alcohol usually taken with meals	0.4	0.7	3.6	-0.1	-0.6	-0.6	-0.8	-1.8	1.9	0.1	-0.4	-0.4	0.4	-1.0	-0.4	-1.1	-0.5	-1.0	-0.5	-0.9	-0.4	-0.2
Diabetes (self-reported)	0.4	0.7	1.9	-0.8	-0.5	-0.9	-0.2	-0.5	1.0	-1.3	-0.8	-0.9	-0.7	-0.7	-0.8	0.2	-0.8	-0.9	-0.9	0.3	-1.4	-0.7
Father’s age at death	0.4	0.6	1.8	-0.6	-0.7	-1.4	0.0	-0.2	-0.8	0.1	-0.8	-0.7	-1.0	-0.9	0.3	-0.8	-0.7	-0.5	-1.0	-0.8	-0.8	-0.9
Number of live births	0.4	0.6	2.2	-0.8	-0.9	0.7	1.0	0.9	-1.5	-0.5	1.0	-0.5	-0.8	0.2	0.5	0.3	-0.8	0.2	0.4	0.6	-0.9	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.1	-1.0	-1.2	-0.1	1.1	1.5	0.2	-0.6	0.1	0.4	0.3	0.0	0.6	1.8	-0.2	0.1	0.2	0.6	-0.5	0.1
Birth weight of first child	0.4	0.8	2.5	0.5	0.6	0.6	1.0	1.0	1.6	0.3	0.8	0.7	1.0	0.4	1.0	1.1	0.6	1.0	0.1	1.0	1.0	1.0
Number of children fathered	0.4	0.5	1.6	0.4	0.6	1.2	1.0	1.2	-0.4	0.4	0.1	-0.2	-0.3	-0.4	0.0	1.2	-0.3	1.1	1.0	0.1	-0.6	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.0	-0.6	-0.4	0.3	0.4	-0.1	-0.3	-0.3	-1.4	-0.3	-1.1	-0.7	-0.5	0.9	-0.5	-1.1	-0.8	-0.9	-0.4	-0.9
Medication for pain relief, constipation, heartburn	0.4	0.7	2.2	0.9	0.7	0.7	-1.5	-0.8	-1.0	-0.7	0.0	0.7	0.9	1.1	-1.3	-0.7	0.6	0.3	0.6	-0.5	1.3	0.5
Medication: Seretide 50 evohaler	0.4	0.5	2.3	-0.0	0.1	-0.4	-0.4	-0.2	-1.5	-1.3	-0.5	-0.3	-0.4	0.2	-1.4	-0.8	-0.2	-0.3	-0.3	-0.3	-0.6	-0.5
Age at last live birth	0.4	0.5	2.6	-0.1	-0.5	0.4	1.6	0.6	1.2	1.0	0.4	0.4	0.2	0.4	0.3	1.2	0.1	0.7	-0.3	-0.2	1.1	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.3	0.1	0.3	0.5	0.3	1.1	-0.6	1.0	0.3	0.6	0.4	1.1	0.3	1.0	0.3	0.9	0.7	0.4	0.9	0.2
Ever had bowel cancer screening	0.4	0.4	1.4	-1.2	-1.1	-0.0	0.3	0.3	-0.6	-0.9	-0.7	-0.3	-0.9	-0.2	-0.5	0.3	-1.1	-0.4	-0.0	-0.9	-0.3	-0.2
Diabetes diagnosed by doctor	0.4	0.7	3.0	-0.8	-0.7	-1.0	-0.7	-0.6	0.4	-1.7	-0.6	-1.0	-0.6	-0.3	-1.2	0.1	-0.8	-0.8	-0.8	0.4	-1.4	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.7	0.3	0.0	0.4	0.6	0.6	-0.2	0.7	1.1	0.5	1.2	0.6	0.3	-0.2	0.4	1.3	0.5	-0.1	0.5	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.0	-1.2	-1.0	-0.8	-0.2	0.8	-1.2	-0.1	-0.7	-0.9	-1.1	-0.2	0.1	0.7	-1.0	-0.4	-0.7	-0.1	-1.4	-0.9
Mineral and other dietary supplements	0.4	0.6	1.6	1.3	1.0	1.0	-0.7	0.1	0.2	0.3	1.1	0.6	0.7	0.3	-0.3	-1.1	0.4	1.0	1.0	0.7	0.4	0.9
Osteoporosis (self-reported)	0.4	0.5	1.7	0.7	0.5	0.5	-0.0	0.5	1.3	0.9	-0.2	0.2	0.2	-0.6	1.1	1.0	0.2	0.0	1.2	0.8	-0.5	0.5
Osteoarthritis (self-reported)	0.4	0.5	2.1	0.5	0.6	-0.2	1.5	1.0	-0.9	0.1	0.7	0.6	0.5	0.5	0.0	1.1	0.5	0.9	0.6	1.1	0.4	0.5
Myopia	0.4	0.7	5.2	0.2	-0.1	0.5	1.6	0.1	0.7	1.1	0.2	1.2	-0.2	-0.0	0.2	0.6	0.7	0.2	0.3	0.4	2.3	0.0
Age at First Birth	0.3	0.5	2.1	0.9	0.7	0.6	1.4	0.4	0.4	0.6	0.3	-0.0	0.5	-0.2	1.1	1.0	0.3	0.6	0.3	0.9	0.7	0.6
Schizophrenia (2014)	0.3	0.7	3.1	0.4	0.7	0.3	0.9	0.6	1.3	0.8	0.3	0.1	0.0	-1.1	1.8	1.2	0.3	-0.1	1.4	0.6	-0.8	0.1
Hypothyroidism (self reported)	0.3	0.7	6.6	0.2	0.6	-0.4	0.5	0.7	-0.7	-2.6	-0.2	0.1	0.0	-0.3	-0.0	0.3	0.2	-0.1	-0.8	0.2	-1.8	0.7
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.5	-0.7	-0.4	-0.8	0.1	-0.2	1.1	-1.6	-0.5	-0.4	-0.8	-0.4	-0.5	0.8	-0.2	-0.7	-0.9	0.5	-0.9	-0.3
Impedance of leg (right)	0.3	1.3	5.8	-0.8	-0.7	-1.1	-1.9	-0.7	-0.9	0.7	-2.3	-0.5	-1.6	-0.1	-0.4	-0.2	-0.3	-1.1	-0.2	-2.4	-0.3	-0.9
Taking other prescription medications	0.3	0.4	1.1	0.6	0.9	1.0	1.0	0.9	-0.1	-0.1	0.1	0.8	-0.3	0.7	0.5	1.0	0.5	0.1	1.0	0.6	-0.1	0.2
Alcohol intake versus 10 years previously	0.3	0.5	2.3	0.4	0.6	1.5	0.2	-0.3	-1.1	-1.3	1.0	0.2	0.5	0.9	-0.0	-0.6	-0.1	0.2	-0.2	0.1	0.4	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.4	-0.3	-0.3	0.7	0.4	1.5	0.3	0.5	1.1	0.7	-0.2	0.3	1.3	1.1	0.3	0.2	0.7	0.7	0.0	0.4
Illnesses of mother	0.3	0.4	1.9	0.3	0.5	0.5	0.7	1.4	0.3	0.3	0.3	0.1	0.7	-0.0	0.6	0.6	0.3	1.4	0.4	0.1	0.2	0.6
Standing height	0.3	2.6	7.7	0.8	0.3	2.6	2.8	2.2	1.0	1.5	1.2	1.8	1.0	1.3	1.8	2.0	1.2	1.6	1.3	1.3	1.3	1.3
Exposure to tobacco smoke at home	0.3	0.3	3.6	-0.2	0.1	-0.4	-0.3	0.0	-0.0	-1.9	-0.6	-0.1	0.4	-0.2	-0.4	0.4	0.1	-0.2	-0.7	0.1	-0.9	-0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.0	0.1	-0.3	0.6	1.0	0.6	0.1	0.9	0.5	0.8	-0.3	0.4	-0.4	1.4	0.4	-0.0	0.8	0.6	0.9	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.4	-0.5	-0.9	-0.3	-0.6	-0.0	-1.2	-0.9	-0.9	-0.0	-1.0	-0.5	-0.5	0.5	-0.7	-1.0	-0.6	-0.9	-0.3	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	3.3	0.8	1.2	0.1	1.2	0.9	-0.4	-1.8	0.2	0.7	0.4	0.2	0.3	0.3	0.7	0.3	-0.1	0.6	-1.1	1.2
Medication: Omeprazole	0.3	0.4	3.8	-0.6	-0.2	-0.1	1.9	0.8	0.2	-0.1	-0.1	0.0	0.4	-0.8	0.5	0.4	-0.3	0.2	-0.6	0.6	-0.4	-0.5
Family relationship satisfaction	0.3	0.4	2.1	1.0	0.7	0.4	-0.4	-0.2	0.3	-0.1	0.4	0.5	0.9	1.2	0.0	-0.5	0.5	0.5	-0.2	0.6	1.5	0.4
Average weekly red wine intake	0.3	0.5	1.3	0.1	-0.3	-1.1	-0.9	-0.7	-0.7	-0.7	-0.8	-0.3	-0.0	-1.0	-0.7	-1.1	-0.2	-0.4	-0.8	-1.0	0.0	0.1
Mood swings	0.3	0.5	2.1	-0.3	0.1	0.0	1.4	1.0	1.2	0.4	0.1	0.4	-0.5	0.7	1.1	1.4	0.3	-0.1	0.4	0.6	-0.2	-0.1
Number of self-reported non-cancer illnesses	0.3	0.6	1.1	0.8	0.9	0.9	1.0	1.0	-0.0	0.5	0.8	1.1	0.3	0.4	0.5	1.0	0.9	0.5	1.1	0.8	0.3	0.4
Medication: Lisinopril	0.3	0.4	2.4	-0.5	-0.2	-0.8	-0.6	-0.3	1.0	-0.0	-0.2	-0.4	0.2	0.2	0.2	-0.9	-0.2	-0.1	-1.4	-0.1	0.1	-1.6
Medication: Atorvastatin	0.3	0.3	0.9	1.0	0.7	0.4	-0.4	-0.4	0.6	0.9	0.9	0.3	0.5	0.5	0.7	-0.4	0.4	0.3	0.3	0.8	0.6	0.3
Fractured/broken bones in last 5 years	0.3	0.4	2.3	0.3	0.6	0.4	1.1	0.4	0.6	1.1	0.4	0.3	0.1	0.0	0.7	1.5	0.1	-0.1	0.1	0.7	0.0	0.2
Commuting to job workplace: Cycle	0.3	0.4	1.4	0.7	0.5	0.8	0.6	0.6	-0.5	-0.7	0.8	0.1	0.7	0.6	-0.2	0.3	0.5	1.0	-0.0	0.0	-0.6	1.2
Basal cell carcinoma (self-reported)	0.3	0.3	1.0	0.8	0.6	0.7	0.7	0.1	0.3	-0.1	0.7	0.5	0.5	1.0	0.2	0.9	0.7	0.2	0.4	0.9	0.0	0.2
Alzheimer’s Disease (in father)	0.2	0.2	1.3	-0.0	0.1	-0.6	-0.7	0.2	-1.1	-0.6	-0.3	-0.1	0.2	-0.2	-0.3	-1.0	-0.0	0.3	-0.0	-0.4	-0.5	0.1
Major Depression (MDD)	0.2	0.3	1.4	-0.2	-0.3	-0.1	0.4	1.2	-1.1	0.3	0.4	0.5	-0.5	0.2	0.3	1.0	0.2	0.3	0.3	0.1	-0.3	0.6
Reaction Time	0.2	0.5	3.3	-0.5	-0.6	-1.1	0.0	-0.3	-0.8	-1.8	-0.2	-0.6	-0.4	-0.3	-0.8	-0.5	-0.6	-0.3	-0.8	0.2	-0.2	-0.2
Breast Cancer	0.2	0.4	1.7	0.3	0.3	-0.2	-0.9	-0.4	-0.9	-1.1	-0.2	-0.5	0.6	0.1	-0.7	-1.3	-0.3	0.3	0.1	-0.3	-1.0	0.4
HbA1C	0.2	0.2	1.6	0.1	0.2	0.2	1.3	0.2	0.5	0.1	0.6	0.4	-0.2	0.1	0.2	0.0	0.3	0.0	-0.3	0.6	0.4	0.3
Primary Biliary Cirrhosis	0.2	0.4	2.6	0.4	0.3	0.3	-0.1	-0.7	0.6	1.4	0.1	0.2	-0.3	0.6	-0.7	0.3	0.3	0.1	0.3	0.1	1.6	0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.9	0.3	0.0	0.5	-0.6	-0.0	0.2	-0.1	0.3	0.2	-0.0	0.8	-0.6	0.2	0.3	0.1	1.0	0.5	-0.4	0.4
Heel T-Score	0.2	1.4	5.8	-0.8	-0.7	-0.3	-1.6	-1.3	-2.4	-1.1	-1.2	-0.7	-1.1	-0.4	-2.2	-0.4	-0.6	-1.4	-0.3	-1.6	-0.7	-0.8
Hand grip strength (left)	0.2	0.6	2.2	-1.4	-1.5	-0.6	0.3	-0.5	0.0	-0.2	-0.7	-0.8	-0.3	-1.4	-0.8	-0.3	-0.5	-0.8	-0.6	-0.1	-1.1	-0.6
Number of treatments/medications taken	0.2	0.4	1.8	0.1	0.5	-0.5	1.2	1.0	1.0	0.1	-0.1	-0.0	-0.2	-0.1	1.3	0.8	0.2	-0.1	0.2	0.7	-1.1	-0.3
Relative age of first facial hair	0.2	0.3	1.2	-0.3	-0.3	0.0	0.5	0.2	0.3	0.4	-0.5	0.7	-0.9	-1.1	0.0	0.7	0.9	-0.7	0.4	-0.2	0.6	-0.2
Medication: Co-codamol	0.2	0.2	1.1	0.4	0.7	-0.2	0.5	0.7	-0.3	0.1	-0.2	0.1	-1.1	-0.4	0.5	0.6	-0.0	0.3	-0.0	-0.3	0.7	0.2
Hand grip strength (right)	0.2	0.5	2.0	-0.6	-1.1	-0.3	-0.5	-1.4	0.0	-0.4	-0.4	-0.5	-0.1	-0.9	-1.4	-0.9	-0.2	-1.1	0.1	-0.2	-0.8	0.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.1	-0.2	-0.2	0.1	-0.4	0.6	-1.0	-0.4	0.5	-0.1	0.4	-0.6	-0.0	-0.2	-0.4	0.7	0.4	-0.3	-0.6	0.5
Medication: Atenolol	0.2	0.3	0.7	0.9	0.7	0.6	-0.4	-0.4	0.5	0.6	0.7	0.1	0.2	0.6	0.5	-0.6	0.5	0.2	0.2	0.2	0.6	-0.4
Sitting height	0.2	1.1	4.4	0.2	-0.2	1.9	2.1	1.4	0.8	0.6	1.0	0.9	1.0	0.9	1.0	1.0	0.4	1.1	0.9	1.1	-0.2	1.1
Number of incorrect matches in round	0.2	0.3	1.7	-0.0	-0.1	0.6	-0.2	0.3	1.0	-0.1	0.1	0.8	0.4	0.4	0.8	1.3	0.5	-0.1	0.5	0.2	0.7	-0.1
Nervous feelings	0.2	0.4	2.3	-0.3	-0.5	0.3	1.5	1.5	0.3	-0.5	-0.4	0.5	0.3	-0.2	0.3	1.4	0.3	0.4	0.3	-0.1	0.2	0.3
Had menopause	0.2	0.2	0.9	0.6	0.4	0.2	0.5	-0.0	0.4	0.5	0.1	0.4	0.4	0.9	0.5	0.4	0.4	0.1	0.7	0.4	0.1	0.6
Medication: Ramipril	0.2	0.3	0.9	0.2	0.4	0.0	-0.9	-0.6	-0.9	0.9	0.1	-0.5	0.4	-0.3	-0.2	-0.9	-0.0	0.3	0.5	0.3	-0.2	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.2	-0.6	-0.6	-1.1	0.9	0.6	0.1	-0.2	0.0	-0.2	0.5	0.1	0.6	-0.4	-0.4	0.4	-0.9	0.1	-0.1	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	3.1	-0.4	0.4	-0.0	-0.2	0.3	-1.8	0.5	0.1	-0.5	0.2	-0.0	-0.3	-0.1	-0.6	0.4	0.6	0.3	-0.1	-0.5
High blood pressure (siblings)	0.2	0.3	0.8	0.7	0.6	0.4	-0.6	-0.8	0.5	0.1	-0.3	0.3	-0.9	0.9	0.1	0.1	0.4	-0.8	0.3	-0.4	0.4	-0.4
Number of full brothers	0.2	0.3	1.5	-0.6	-0.9	0.5	0.1	0.0	-0.6	-0.1	0.0	-0.1	-0.2	0.8	-0.8	0.3	-0.4	-0.0	0.0	-0.1	1.2	-0.1
Eye problems/disorders: None of the above	0.2	0.2	0.7	-0.8	-0.5	-0.1	0.3	0.6	0.1	0.7	-0.3	-0.3	-0.2	0.0	0.3	-0.3	-0.4	0.5	0.2	-0.7	-0.1	-0.4
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.5	0.7	0.2	-0.4	0.1	-0.9	0.3	0.4	-0.5	-0.5	-0.2	-0.6	-0.2	-0.6	0.6	0.2	-0.4	-0.4	0.1
Medication: Blood pressure	0.2	0.3	2.2	-0.2	0.2	-0.5	-0.2	-0.6	1.0	0.3	-0.2	-0.8	0.1	-0.5	-0.4	-1.5	-0.0	0.3	-0.1	-0.1	-0.5	-1.1
Mean time to correctly identify matches	0.2	0.4	3.1	-0.0	-0.1	-0.5	0.4	0.0	-1.4	-1.8	0.2	-0.0	-0.1	0.5	-0.6	-0.7	-0.2	0.2	-0.3	0.2	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	0.1	-0.0	0.8	1.3	1.0	1.3	-0.2	0.0	0.2	0.1	-0.2	0.7	1.1	0.4	0.2	0.5	0.5	-0.8	0.6
Commuting to job workplace: Walk	0.2	0.2	0.8	0.5	0.7	0.3	-0.6	-0.5	-0.4	0.0	-0.3	-0.1	-0.9	-0.1	-0.2	-0.3	0.1	-0.5	0.5	-0.0	-0.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.1	-0.1	0.1	-0.5	-0.6	-0.5	0.4	-0.7	-1.1	0.0	-0.7	-0.7	0.3	0.4	-0.1	-0.9	-0.1	-0.3	0.2	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.0	-0.0	0.2	-0.3	0.9	-0.0	-1.0	0.3	-0.3	-0.3	-0.2	0.8	0.7	0.3	-0.1	-0.0	-0.5	-0.5	0.1	0.0
Illnesses of father: High blood pressure	0.2	0.2	0.6	0.1	-0.2	0.1	0.5	0.4	0.7	-0.1	0.5	0.5	0.2	0.5	-0.3	0.8	0.6	0.1	0.2	0.7	-0.2	0.4
Alcohol drinker status: Never	0.2	0.2	0.7	0.1	-0.1	0.8	-0.4	-0.4	0.3	-0.3	0.4	0.4	0.6	0.7	-0.5	0.6	0.3	0.1	0.8	0.2	0.7	0.1
Irritability	0.2	0.3	1.3	-0.5	-0.9	-0.5	0.3	1.2	0.4	0.1	-0.5	0.8	-0.5	-0.2	0.3	0.8	0.5	-0.1	-0.5	-0.1	0.1	0.0
Ever had prostate specific antigen (PSA) test	0.2	0.3	2.5	0.0	-0.4	0.7	-0.4	-0.3	0.8	0.0	0.3	0.6	-0.2	0.2	-0.1	0.6	0.5	-0.2	-0.1	-0.4	1.6	0.1
Cholesterol lowering medication	0.2	0.3	1.9	-0.2	-0.0	-0.3	-1.4	-0.3	-0.4	-0.0	0.9	-0.4	0.8	0.2	-0.3	-0.9	-0.2	0.4	-0.4	1.0	-0.5	-0.3
Irritable Bowel Disease (IBD)	0.1	0.4	1.1	0.1	0.3	0.1	0.0	0.9	-0.9	1.1	0.6	0.5	0.1	0.0	0.2	0.7	0.4	0.6	0.9	0.9	0.8	0.2
Ulcerative Colitis (UC)	0.1	0.3	1.1	-0.6	-0.6	-0.8	-0.7	-0.2	-0.4	-0.6	-0.2	-0.3	0.2	-1.1	-0.3	-0.1	-0.1	-0.4	-0.3	0.1	-0.2	-0.8
Ulcerative Colitis	0.1	0.2	1.2	0.0	-0.1	0.1	0.2	0.2	-0.2	-0.1	0.5	0.3	1.1	0.5	0.2	0.2	0.4	0.4	0.4	0.7	0.1	0.3
Blood Red Count	0.1	0.9	3.6	-0.3	0.0	0.5	-1.1	-1.3	-0.6	-0.3	-1.0	-1.1	-1.9	-0.5	-0.6	-0.2	-0.7	-1.1	-0.6	-1.4	-0.1	-1.6
Blood White Count	0.1	0.8	4.2	1.3	2.0	0.5	-1.1	0.7	-0.7	-0.3	1.4	0.1	0.1	0.5	1.2	-0.6	0.0	1.0	0.2	0.5	-0.5	1.3
Ever had hysterectomy (womb removed)	0.1	0.1	0.5	0.3	-0.1	0.7	-0.4	-0.4	0.4	0.5	-0.4	0.4	-0.5	-0.1	0.1	0.0	0.4	-0.2	0.1	-0.2	0.4	-0.1
Relative age voice broke	0.1	0.2	0.7	0.5	0.3	0.6	-0.9	-0.6	-0.7	0.1	0.1	0.4	0.0	-0.1	-0.6	0.0	0.7	-0.2	0.6	-0.1	0.5	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.3	-0.2	-0.5	-0.2	-0.6	-0.3	0.2	0.4	-0.5	-0.4	-0.1	-1.1	-0.6	0.1	0.2	-0.3	-0.1	-0.3	-0.8	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	2.7	-0.1	-0.3	-0.7	0.2	-0.2	0.5	0.1	-0.7	-0.4	-0.5	-1.6	-0.9	0.3	0.1	-0.4	-0.7	-0.0	0.0	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.6	0.1	-0.1	-0.4	1.0	-0.1	1.3	0.3	-0.3	0.4	0.4	0.0	0.7	0.3	0.6	-0.2	-0.3	0.1	0.8	0.1
Glaucoma (self-reported)	0.1	0.1	0.7	-0.1	-0.1	-0.1	-0.0	-0.2	0.3	-0.1	-0.3	-0.1	-0.4	-0.6	0.3	0.1	-0.4	-0.8	-0.4	-0.4	-0.6	-0.2
Comparative height size at age 10	0.1	0.6	2.9	-0.8	-0.9	0.5	1.7	0.6	0.7	0.5	-0.9	0.2	-0.6	0.2	0.8	1.2	-0.0	-0.4	0.3	0.2	0.1	-1.0
Number of full sisters	0.1	0.2	0.5	-0.6	-0.7	-0.4	-0.0	0.2	0.3	-0.5	0.0	-0.4	0.2	-0.6	0.1	-0.3	-0.6	-0.0	-0.5	0.4	-0.5	-0.5
Medication: Gliclazide	0.1	0.2	0.5	0.3	0.1	0.1	-0.3	0.3	-0.1	0.3	0.6	0.4	0.4	0.2	-0.2	-0.4	0.4	0.7	0.4	0.4	0.6	0.7
Eye problems/disorders: Glaucoma	0.1	0.1	0.6	0.2	-0.1	0.3	-0.1	-0.3	0.6	-0.4	-0.2	-0.0	-0.2	-0.3	-0.1	0.2	-0.2	-0.8	0.1	-0.2	-0.8	0.3

Hub : Genes

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Models

Trait associations