[Hub]/) : Traits : BMI : ← →

chr2:53,384,500-56,036,348

Best TWAS P=2.32e-10 · Best GWAS P=4.53e-14 conditioned to 3.3e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ACYP2 0.06 0.02 blup 561 0.03 4.8e-05 -4.6 5.3 8.6e-08 0.10 0.32 0.55 FALSE
2 GTEx Artery Aorta HMGB1P31 0.17 0.05 enet 31 0.07 7.4e-05 4.2 -5.5 3.1e-08 -0.03 0.50 0.33 FALSE
3 GTEx Artery Tibial HMGB1P31 0.17 0.00 enet 21 0.06 1.8e-05 -4.4 -5.7 1.3e-08 -0.01 0.11 0.42 TRUE
4 GTEx Brain Hypothalamus GPR75 0.33 0.01 lasso 6 0.02 8.7e-02 -4.5 -5.2 2.0e-07 -0.07 0.06 0.14 FALSE
5 GTEx Breast Mammary Tissue RTN4 0.33 0.18 lasso 4 0.29 3.6e-15 -5.6 -5.4 7.4e-08 0.44 1.00 0.00 FALSE
6 GTEx Nerve Tibial HMGB1P31 0.14 0.02 enet 19 0.09 9.1e-07 -4.3 -5.2 1.6e-07 -0.03 0.05 0.94 FALSE
7 GTEx Pituitary RTN4 0.26 0.09 lasso 4 0.10 2.0e-03 -5.6 -5.3 1.0e-07 0.45 0.09 0.23 FALSE
8 GTEx Pituitary RP11-477N3.1 0.33 0.18 lasso 5 0.21 6.3e-06 -5.5 -5.4 6.0e-08 -0.07 0.02 0.91 FALSE
9 GTEx Prostate HMGB1P31 0.53 0.19 enet 25 0.27 1.5e-07 -4.8 -5.3 1.3e-07 -0.04 0.36 0.38 FALSE
10 GTEx Stomach RTN4 0.20 0.12 lasso 2 0.14 2.9e-07 4.1 -5.2 2.0e-07 0.41 0.98 0.00 FALSE
11 GTEx Testis RTN4 0.26 0.11 lasso 4 0.17 7.4e-08 3.7 -5.2 1.7e-07 0.46 0.97 0.02 FALSE
12 GTEx Testis HMGB1P31 0.17 0.01 enet 21 0.02 4.6e-02 -1.1 -5.5 4.5e-08 -0.02 0.27 0.17 FALSE
13 ROSMAP Brain Pre-frontal Cortex HMGB1P31 0.07 0.07 lasso 7 0.07 7.3e-10 -4.3 -5.5 3.5e-08 -0.06 0.59 0.39 FALSE
14 YFS Blood RTN4 0.04 0.03 bslmm 584 0.03 1.9e-09 -6.0 -6.3 2.3e-10 0.50 0.95 0.05 TRUE
15 The Cancer Genome Atlas Thyroid Carcinoma ACYP2 0.15 0.09 enet 8 0.12 2.0e-11 3.1 5.1 2.9e-07 0.05 0.38 0.53 FALSE