Best TWAS P=7.44e-09 · Best GWAS P=7.29e-08 conditioned to 0.0629
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | HINT1 | 0.10 | 0.07 | enet | 16 | 0.06 | 8.8e-06 | -5.1 | -5.8 | 7.4e-09 | 0.70 | 0.04 | 0.95 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | HINT1 | 0.10 | 0.06 | lasso | 2 | 0.05 | 2.1e-04 | -5.1 | -5.4 | 5.7e-08 | 0.94 | 0.04 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | HINT1 | 0.07 | 0.04 | lasso | 2 | 0.01 | 1.8e-02 | -5.4 | -5.4 | 7.3e-08 | 1.00 | 0.00 | 0.98 | FALSE |