Best TWAS P=3.2e-08 · Best GWAS P=1.58e-08 conditioned to 0.00514
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RAB24 | 0.14 | 0.06 | enet | 14 | 0.09 | 4.2e-11 | -5.1 | -5.3 | 9.2e-08 | 0.57 | 0.04 | 0.96 | TRUE |
| 2 | METSIM | Adipose | RAB24 | 0.05 | 0.02 | lasso | 4 | 0.02 | 1.2e-03 | -5.1 | -5.2 | 2.5e-07 | 0.60 | 0.03 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MXD3 | 0.05 | 0.00 | lasso | 6 | 0.00 | 6.9e-01 | 5.5 | 5.5 | 3.2e-08 | -0.06 | 0.00 | 0.84 | TRUE |