Best TWAS P=8e-10 · Best GWAS P=3.49e-10 conditioned to 5.2e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC25A37 | 0.08 | 0.05 | lasso | 5 | 0.05 | 4.8e-07 | -4.7 | 5.4 | 7.5e-08 | -0.16 | 0.25 | 0.74 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SLC25A37 | 0.13 | 0.05 | lasso | 5 | 0.04 | 3.0e-04 | -6.3 | 6.1 | 8.0e-10 | -0.14 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SLC25A37 | 0.11 | 0.09 | lasso | 5 | 0.09 | 7.8e-10 | -5.1 | -5.7 | 1.2e-08 | 0.32 | 0.67 | 0.33 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC25A37 | 0.04 | 0.02 | lasso | 2 | 0.03 | 1.1e-04 | -5.1 | -5.1 | 2.9e-07 | 0.31 | 0.07 | 0.20 | FALSE |