Best TWAS P=7.87e-09 · Best GWAS P=9.81e-12 conditioned to 3.93e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | C8orf46 | 0.27 | 0.26 | enet | 23 | 0.22 | 3.7e-12 | 3.8 | 5.3 | 1.3e-07 | -0.46 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | ADHFE1 | 0.37 | 0.22 | enet | 23 | 0.13 | 3.0e-04 | 4.3 | -5.3 | 9.3e-08 | 0.62 | 0.45 | 0.24 | FALSE |
| 3 | GTEx | Colon Transverse | C8orf46 | 0.19 | 0.06 | enet | 11 | 0.03 | 1.6e-02 | -3.9 | 5.8 | 7.9e-09 | -0.62 | 0.10 | 0.57 | TRUE |