Best TWAS P=6.21e-23 · Best GWAS P=3.91e-28 conditioned to 1.09e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ATP2B1 | 0.08 | 0.01 | enet | 10 | 0.03 | 3.5e-03 | -11.0 | -9.9 | 6.2e-23 | 0.87 | 0.01 | 0.96 | TRUE |
| 2 | GTEx | Lung | RP11-981P6.1 | 0.08 | 0.01 | lasso | 3 | 0.01 | 3.9e-02 | -4.7 | -6.8 | 7.9e-12 | 0.60 | 0.25 | 0.28 | FALSE |
| 3 | GTEx | Prostate | POC1B | 0.25 | 0.00 | enet | 37 | 0.01 | 1.6e-01 | -10.1 | 6.7 | 1.7e-11 | -0.50 | 0.02 | 0.63 | FALSE |
| 4 | METSIM | Adipose | POC1B | 0.07 | 0.03 | bslmm | 381 | 0.03 | 5.2e-05 | -4.6 | 5.4 | 7.2e-08 | -0.55 | 0.90 | 0.02 | FALSE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | LOC338758 | 0.14 | 0.00 | enet | 6 | 0.01 | 6.2e-02 | 1.8 | -7.4 | 1.5e-13 | 0.31 | 0.01 | 0.07 | TRUE |