TWAS
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Traits
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Cardiovascular Disease
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chr12:109,591,369-111,015,121
Best TWAS P=3.75e-08 · Best GWAS P=2.16e-08 conditioned to 0.0277
109.6M
109.8M
110M
110.2M
110.4M
110.6M
110.8M
111M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
TCHP
0.05
0.01
blup
56
0.03
0.0014
3.8
-5.5
3.7e-08
0.76
0.04
0.62
TRUE
1
GTEx
Breast Mammary Tissue (Female)
GLTP
0.14
0.06
lasso
6
0.06
0.0077
-5.6
-5.4
5.4e-08
0.83
0.02
0.82
FALSE