[Hub]/) : Traits : Cardiovascular Disease :

chr16:3,015,262-5,593,819

Best TWAS P=1.14e-10 · Best GWAS P=1.17e-10 conditioned to 5.97e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GLYR1 0.14 0.03 bslmm 416 0.07 3.8e-09 -2.3 5.7 1.2e-08 -0.50 0.64 0.28 TRUE
2 GTEx Adipose Visceral Omentum AC006111.1 0.18 0.12 enet 12 0.10 1.1e-05 4.5 6.5 1.1e-10 0.02 0.64 0.06 TRUE
3 GTEx Brain Cortex AC006111.1 0.32 0.02 enet 16 0.00 3.2e-01 -4.3 6.2 6.1e-10 -0.04 0.03 0.31 TRUE
4 GTEx Pancreas TRAP1 0.36 0.09 lasso 6 0.13 2.9e-06 -3.6 5.3 1.4e-07 0.01 0.18 0.09 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic AC006111.1 0.19 0.12 enet 13 0.18 2.1e-10 -3.6 5.8 5.1e-09 0.02 0.52 0.45 FALSE
6 GTEx Skin Sun Exposed Lower leg AC006111.1 0.23 0.10 enet 25 0.12 9.2e-10 -3.6 5.1 3.0e-07 0.03 0.97 0.02 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma NAT15 0.05 0.04 blup 56 0.03 1.7e-07 4.6 -5.1 2.9e-07 -0.02 0.91 0.09 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma UBN1 0.05 0.04 enet 7 0.05 4.2e-04 5.2 -5.5 3.7e-08 0.67 0.04 0.51 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TRAP1 0.11 0.01 blup 43 0.05 9.4e-04 -1.5 5.5 5.1e-08 0.02 0.00 0.18 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma NAT15 0.06 0.04 blup 56 0.04 4.1e-05 5.1 -5.7 1.4e-08 -0.01 0.09 0.78 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NAT15 0.04 0.01 blup 56 0.04 4.2e-05 4.9 -5.9 3.3e-09 -0.05 0.16 0.46 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma NAT15 0.10 0.05 lasso 6 0.07 6.1e-07 5.0 -5.3 1.4e-07 -0.04 0.76 0.22 FALSE