TWAS hub - NAT15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0515	0.0214	2.8e-07	0.039	0.033	0.027	NA	0.031	1.9e-08	1.7e-07	2.0e-06	NA	5.0e-07
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.1988	0.0644	1.1e-09	0.056	0.085	0.071	NA	0.077	6.4e-07	9.0e-10	1.9e-08	NA	4.6e-09
3	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0660	0.0350	6.0e-03	-0.004	0.029	0.007	NA	-0.001	6.0e-01	8.8e-03	1.2e-01	NA	3.9e-01
4	TCGA	Lung Adenocarcinoma	0.0601	0.0280	8.9e-05	0.038	0.036	0.025	NA	0.030	2.4e-05	4.1e-05	5.8e-04	NA	1.9e-04
5	TCGA	Lung Squamous Cell Carcinoma	0.0414	0.0208	1.2e-04	0.009	0.037	0.020	NA	0.022	2.8e-02	4.2e-05	2.0e-03	NA	1.4e-03
6	TCGA	Pancreatic Adenocarcinoma	0.2990	0.0810	1.7e-06	0.191	0.196	0.170	NA	0.175	1.9e-08	1.2e-08	1.3e-07	NA	8.1e-08
7	TCGA	Pheochromocytoma and Paraganglioma	0.1000	0.0670	8.9e-03	0.005	0.001	-0.007	NA	-0.006	2.0e-01	2.7e-01	7.8e-01	NA	6.4e-01
8	TCGA	Soft Tissue Sarcoma	0.1970	0.0700	6.3e-07	0.077	0.156	0.172	NA	0.145	2.6e-05	1.6e-09	1.8e-10	NA	5.8e-09
9	TCGA	Thyroid Carcinoma	0.0960	0.0420	1.5e-07	0.047	0.063	0.054	NA	0.065	2.3e-05	9.7e-07	5.4e-06	NA	6.1e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
High blood pressure	8.7	24.2	33.9	-5.8	-2.6	-5.0	-5.7	-5.6	-2.6	-4.6	-5.2	-5.8
Systolic blood pressure, automated reading	8.1	23.7	31.0	-5.6	-3.4	-5.1	-5.5	-5.0	-4.3	-4.9	-4.8	-4.9
Hypertension (Self-reported)	7.8	21.8	30.5	-5.5	-2.2	-4.6	-5.4	-5.4	-2.5	-4.3	-5.1	-5.5
Vascular/heart problems diagnosed by doctor	7.0	19.1	28.3	4.9	2.3	4.2	5.2	5.3	1.9	4.4	4.4	5.3
Number of self-reported non-cancer illnesses	6.9	12.0	19.3	-4.0	-1.9	-3.3	-3.6	-4.4	-1.6	-4.1	-3.0	-4.0
Cardiovascular Disease	6.7	22.2	35.0	-5.1	-2.5	-4.2	-5.7	-5.9	-2.6	-5.0	-4.7	-5.3
Average weekly red wine intake	6.6	9.7	19.9	3.1	3.4	2.3	3.3	3.3	2.0	4.5	2.3	3.1
Lung FVC	6.0	30.5	47.2	-5.1	-6.9	-5.7	-6.3	-5.2	-4.1	-4.5	-5.3	-6.0
Systolic Blood Pressure	5.9	29.5	47.7	-5.8	-3.8	-4.9	-6.9	-5.9	-5.3	-4.9	-5.5	-5.4
Diastolic blood pressure, automated reading	5.1	15.7	21.0	-4.6	-2.6	-4.0	-4.3	-4.2	-3.6	-4.4	-3.7	-3.9
Noisy workplace	4.9	6.1	10.5	-2.5	-2.2	-2.4	-3.2	-2.7	-1.4	-2.6	-1.8	-2.7
Medication: Blood pressure	4.9	9.4	15.3	-3.3	-1.2	-2.8	-3.5	-3.9	-1.4	-2.6	-3.8	-3.6
High blood pressure (mother)	4.4	6.2	11.6	-2.5	-1.9	-2.1	-2.4	-3.4	-0.9	-2.3	-3.0	-2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.4	9.3	15.0	-3.2	-3.6	-3.9	-2.1	-3.0	-0.1	-3.4	-2.4	-3.8
Medication: Co-codamol	4.3	5.0	10.6	2.5	2.0	3.3	1.9	1.5	1.3	2.2	2.4	2.5
Past tobacco smoking	4.1	7.4	12.2	2.7	2.8	2.0	2.3	3.4	2.3	3.5	2.7	2.6
Diabetes (self-reported)	4.1	6.3	8.8	2.4	2.8	2.6	3.0	2.3	2.0	1.7	2.8	2.9
High blood pressure (siblings)	4.0	5.7	11.1	-2.6	-1.3	-1.8	-2.7	-3.3	-1.0	-2.7	-1.7	-3.2
Medication for cholesterol, blood pressure or diabetes	3.9	6.5	9.6	2.9	1.9	2.1	3.1	2.7	2.0	2.4	3.1	2.3
Blood Eosinophil Count	3.6	27.9	46.4	-5.0	-5.7	-4.2	-5.9	-5.0	-5.7	-4.6	-6.8	-4.1
Had major operations	3.6	4.3	7.7	-2.8	-2.1	-1.2	-2.4	-2.6	-0.3	-1.4	-1.9	-2.5
Smoking status: Previous	3.6	5.5	10.4	-2.5	-1.9	-1.6	-1.8	-2.9	-2.2	-3.2	-2.1	-2.3
Loud music exposure frequency	3.5	3.8	6.9	-2.0	-2.2	-1.6	-1.3	-1.8	-1.5	-2.5	-2.6	-1.6
Medication: Simvastatin	3.4	5.0	11.5	-2.3	-1.5	-1.7	-2.3	-3.4	-0.5	-2.8	-1.9	-2.6
Pulse wave peak to peak time	3.4	4.0	7.9	2.4	1.1	2.8	2.1	1.6	1.0	1.4	2.0	2.6
Diabetes (mother)	3.2	4.1	6.5	2.5	1.7	2.2	2.5	2.0	0.6	0.9	2.2	2.5
Pulse wave Arterial Stiffness index	3.2	3.7	6.7	-2.3	-1.4	-2.6	-2.1	-1.5	-1.1	-1.2	-2.0	-2.4
Tinnitus: Yes, now most or all of the time	3.2	3.8	7.3	-2.2	-1.6	-2.7	-2.3	-1.8	-0.1	-1.6	-1.0	-2.6
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	6.4	1.5	1.0	1.6	2.3	2.4	1.0	2.5	1.0	2.1
Diabetes (father)	3.0	3.7	6.0	1.8	1.6	2.1	1.9	2.4	1.1	1.9	2.0	2.2
Medication for cholesterol	2.9	4.3	7.8	2.5	0.7	1.9	2.2	2.8	1.0	1.5	2.6	2.4
Medication: Levothyroxine sodium	2.7	4.5	9.8	-2.7	-0.7	-3.1	-2.1	-1.0	-1.6	-1.7	-2.7	-2.3
Migraine (self-reported)	2.7	3.4	5.7	-2.0	-2.0	-1.4	-1.8	-2.0	-1.6	-1.6	-2.4	-1.6
Diabetes diagnosed by doctor	2.7	4.5	6.2	2.0	2.3	2.4	2.5	1.4	2.0	1.2	2.5	2.3
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.9	6.3	-1.0	-2.2	-0.0	-2.0	-1.8	-2.5	-2.0	-1.4	-0.5
Illnesses of mother	2.6	3.2	7.7	1.7	0.7	1.3	1.8	2.8	0.1	1.9	1.4	2.6
Medication: Blood pressure	2.5	4.4	7.2	-2.6	-1.0	-2.2	-2.7	-1.9	-1.7	-1.7	-2.3	-2.2
Comparative height size at age 10	2.5	13.7	27.4	3.9	3.0	2.3	4.2	5.2	1.9	4.8	2.4	4.2
Forced vital capacity (FVC)	2.4	9.1	22.1	-2.3	-4.7	-3.3	-3.2	-2.1	-2.5	-1.7	-3.6	-2.8
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	11.4	-2.5	-0.3	-3.4	-2.5	-1.0	-1.7	-1.7	-2.7	-2.2
Chronotype (morning person)	2.3	5.2	9.6	3.0	0.3	2.6	1.9	2.7	1.2	2.8	1.1	3.1
Average weekly spirits intake	2.3	2.9	4.9	2.2	0.9	1.8	1.6	1.8	0.3	1.8	2.0	2.1
Illnesses of siblings	2.2	3.0	4.9	1.9	0.8	2.1	2.2	1.9	1.3	1.8	1.0	2.1
Medication: Cholesterol lowering	2.2	3.4	6.4	-2.1	-1.1	-1.6	-1.8	-2.5	-0.3	-2.4	-1.8	-1.9
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	5.2	1.9	0.1	2.3	2.2	1.1	1.1	0.6	1.5	1.9
Birth weight	2.1	4.5	6.9	2.6	0.7	2.1	2.3	2.6	1.3	2.3	2.1	2.3
Forced vital capacity (FVC), Best measure	2.1	7.7	22.8	-1.9	-4.8	-2.8	-2.9	-2.2	-2.0	-1.8	-2.8	-2.6
Alzheimer’s Disease (in father)	2.0	2.2	5.8	1.6	0.3	2.4	1.6	0.2	1.8	1.0	1.8	1.2
Hypothyroidism (self reported)	2.0	4.6	9.0	-2.2	-0.2	-3.0	-2.7	-1.7	-1.0	-1.9	-2.3	-2.6
Birth weight of first child	2.0	3.6	7.1	1.8	1.8	2.7	1.2	2.0	-0.7	2.4	1.0	2.6
Number of full brothers	2.0	2.5	5.2	-1.5	-1.5	-2.0	-1.8	-0.8	-2.3	-1.2	-1.6	-1.0
Pain experienced in last month	2.0	3.3	8.6	-2.3	-1.3	-2.9	-1.3	-0.0	-2.3	-0.6	-2.1	-1.4
Osteoarthritis (self-reported)	1.9	2.5	4.0	1.6	1.6	2.0	1.8	0.7	1.8	0.9	2.0	1.2
Type 2 Diabetes (T2D) (2018)	1.8	3.4	6.7	1.7	1.5	2.3	2.0	1.6	0.9	1.3	2.2	2.6
Medication: Ramipril	1.8	2.3	4.4	-1.5	-2.1	-1.1	-1.3	-1.3	-1.2	-2.0	-1.7	-0.9
Hair/balding pattern: Pattern 4	1.8	4.4	6.6	2.4	2.2	2.5	2.6	1.4	1.4	1.1	2.5	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.6	15.4	-1.9	-3.9	-2.7	-2.1	-2.0	-1.1	-2.0	-2.0	-2.5
Chest pain or discomfort	1.7	2.5	8.2	-1.5	-0.5	-2.1	-0.7	-1.5	0.9	-2.9	-0.6	-1.9
Medication: Bendroflumethiazide	1.7	2.5	6.1	-1.3	-0.3	-1.5	-2.5	-1.9	-0.8	-0.9	-1.7	-2.1
Illnesses of father: High blood pressure	1.7	2.2	4.2	-1.5	-0.7	-2.0	-1.7	-1.1	-1.1	-0.5	-2.0	-1.7
Breast Cancer	1.6	3.9	8.7	-2.8	-1.4	-3.0	-1.7	-1.3	-0.7	-1.6	-1.9	-2.4
Mouth/teeth dental problems	1.6	2.4	5.4	2.0	0.0	1.4	1.7	2.0	0.2	1.5	1.2	2.3
Medication: Lisinopril	1.6	2.0	4.4	-1.4	-1.0	-0.9	-1.8	-2.1	-1.5	-1.3	-1.3	-1.2
Ulcerative Colitis	1.5	2.2	5.0	2.0	0.5	2.2	1.0	1.2	0.5	1.2	2.0	1.7
Relative age of first facial hair	1.5	3.1	4.5	-2.1	-2.0	-1.2	-2.0	-2.1	-1.2	-1.9	-1.2	-1.9
Pain all over the body in last month	1.5	1.6	4.2	1.5	0.5	2.1	0.7	0.9	-0.0	1.2	1.6	1.5
Length of working week for main job	1.5	1.6	6.2	0.8	2.5	1.0	1.3	0.8	1.1	0.7	1.5	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	5.5	-1.5	0.7	-1.3	-0.7	-1.7	-0.5	-2.3	-0.6	-1.6
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	5.7	-0.6	-1.3	-0.6	-0.9	-2.4	-0.2	-1.7	-1.4	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	4.9	-1.1	-1.1	-0.6	-0.4	-1.9	1.3	-2.2	-0.3	-1.7
Maternal smoking around birth	1.4	2.0	4.4	-2.1	0.6	-1.8	-0.9	-0.8	-1.2	-1.5	-1.2	-1.8
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	11.4	-1.9	-3.4	-2.6	-2.0	-1.3	-1.7	-1.4	-2.3	-2.1
Medication: Seretide 50 evohaler	1.4	1.6	4.9	-0.8	-2.2	-0.8	-0.9	-0.9	-0.7	-1.1	-2.2	-0.4
Heart disease (mother)	1.4	1.7	3.0	-1.1	-1.0	-0.3	-1.6	-1.7	-1.6	-1.2	-1.2	-1.3
Mood swings	1.4	2.6	6.9	-1.5	-1.0	-1.2	-1.6	-2.2	-0.6	-2.6	-0.6	-2.0
Pain type(s) experienced in last month: Hip pain	1.4	1.7	8.2	0.3	1.4	0.9	0.2	-1.3	2.9	-0.3	1.4	-0.9
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.3	-0.9	-2.1	-0.9	-1.5	-1.8	-1.1	-1.3	-1.0	-1.3
Basal cell carcinoma (self-reported)	1.4	1.7	3.2	1.6	-0.9	1.5	0.3	1.6	-1.3	1.8	-0.3	1.5
Medication: Metformin	1.3	1.8	4.2	1.0	2.0	1.2	1.4	1.1	1.0	0.7	1.7	1.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.9	0.8	0.9	-0.9	0.6	2.4	0.6	2.1	0.4	0.8
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.4	-1.6	-0.8	-1.3	-1.8	-1.3	-1.7	-1.1	-1.7	-1.4
Miserableness	1.3	2.3	4.2	-1.9	-0.7	-1.1	-1.5	-2.0	-0.5	-1.6	-1.5	-2.0
Ever smoked	1.3	2.2	5.1	-1.4	-1.5	-0.8	-0.7	-2.0	-1.1	-2.3	-1.6	-1.3
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.7	-1.4	-0.8	-1.6	-1.2	-1.3	-0.9	-0.8	-1.0	-1.5
Severe depression (siblings)	1.2	1.3	2.1	-1.2	-1.0	-1.2	-0.9	-1.3	-0.0	-1.3	-1.3	-1.4
Serious illness, injury or assault to yourself	1.2	1.4	5.6	0.5	0.4	1.1	1.7	-0.4	2.4	-0.7	1.5	-0.0
Medication: Atenolol	1.2	1.5	3.0	-1.0	-0.7	-1.3	-1.0	-1.7	0.7	-0.9	-1.6	-1.7
Financial difficulties in last 2 years	1.2	1.6	5.3	-0.7	-0.9	-0.0	-0.9	-2.3	-0.2	-2.2	-0.3	-1.4
Time employed in main current job	1.2	1.4	3.5	1.0	0.4	0.3	1.6	1.9	0.5	1.7	-0.1	1.3
Medication: Lansoprazole	1.2	1.3	3.0	-1.0	-1.7	-0.6	-1.4	-1.5	-0.3	-1.2	-0.9	-1.0
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	3.7	-1.1	0.4	-1.1	-1.0	-1.8	-0.0	-1.9	-0.3	-1.7
Number of children fathered	1.2	1.3	3.4	1.3	0.6	1.8	1.1	0.6	1.0	1.4	0.9	1.1
Health satisfaction	1.2	1.5	5.7	1.7	-0.9	2.4	0.8	0.0	0.2	-0.5	0.7	1.7
Depressed Affect (Nagel 2018)	1.1	2.4	6.0	-1.4	-1.0	-1.1	-1.4	-2.4	-0.0	-1.8	-0.8	-2.4
Depression (Nagel 2018)	1.1	1.6	4.1	-1.3	-0.7	-0.6	-0.8	-2.0	0.2	-1.9	-0.3	-1.8
Ever had hysterectomy (womb removed)	1.1	1.2	3.5	-1.0	-0.7	-0.6	-0.3	-1.9	0.7	-1.7	-0.2	-1.4
Age when periods started (menarche)	1.1	2.6	5.8	-1.3	-1.2	-1.4	-2.4	-1.4	-2.0	-1.1	-1.5	-1.6
Prospective memory result	1.1	1.4	2.3	1.5	-0.0	1.5	1.4	0.9	1.1	0.9	1.5	1.0
Wheeze or whistling in the chest in last year	1.1	1.9	4.3	-1.6	-0.2	-1.8	-1.0	-1.4	-0.8	-2.1	-1.3	-1.2
Qualifications: College or University degree	1.1	3.5	7.7	1.5	1.8	1.7	1.9	2.3	0.7	2.0	1.5	2.8
Medication for pain relief, constipation, heartburn	1.1	1.9	4.9	-1.5	-1.9	-1.3	-0.6	0.3	-2.2	-0.6	-2.0	0.3
Medication: Allopurinol	1.1	1.4	3.2	-1.4	-0.8	-1.0	-1.4	-1.4	-0.9	-0.5	-1.8	-1.1
Leg pain on walking	1.1	1.4	3.5	0.8	1.5	1.6	1.2	0.4	1.1	0.6	1.9	0.8
Eye problems/disorders: Cataract	1.1	1.3	3.0	-1.0	-1.7	-0.7	-1.1	-1.1	-0.9	-0.2	-1.7	-1.0
Unable to work because of sickness or disability	1.1	1.4	4.8	-0.3	-0.8	0.4	0.1	-1.9	2.2	-1.1	-0.1	-1.4
Alzheimer’s Disease (in mother)	1.0	1.2	4.8	-0.5	-0.1	-1.0	0.4	-1.1	2.2	-1.0	0.4	-1.5
Alzheimer’s Disease (including proxy)	1.0	1.4	6.5	-0.4	-0.6	-0.4	0.9	-1.4	2.5	-1.0	0.5	-1.2
Ovarian Cancer	1.0	1.3	5.2	-0.4	-1.3	-0.2	-0.0	-1.4	1.0	-2.3	0.7	-0.9
LDL Cholesterol	1.0	1.6	4.6	-0.9	-2.1	-0.3	-1.2	-1.8	-0.3	-0.8	-1.1	-1.2
Lupus	1.0	1.5	6.2	0.5	-1.1	0.9	0.1	1.0	-2.5	0.6	-0.8	1.8
Diverticular disease/diverticulitis (self-reported)	1.0	1.1	4.8	-0.8	-1.7	-0.9	0.1	-0.1	-0.8	-0.2	-2.2	-0.3
Chronic bronchitis/emphysema (father)	1.0	1.2	6.2	0.2	2.5	0.1	0.9	1.2	0.3	0.1	1.3	0.9
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	4.8	-1.7	0.0	-2.2	-0.7	-0.3	-0.3	-0.5	-1.1	-1.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	3.7	1.1	-0.4	1.9	1.3	-0.1	1.8	-0.6	1.8	1.0
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	4.2	0.8	-1.0	0.8	1.1	1.9	0.2	2.1	-0.2	1.8
Emphysema/chronic bronchitis	1.0	1.1	3.4	-0.9	-1.2	-0.6	-1.0	-0.7	-1.8	-0.8	-1.5	-0.2
Loneliness, isolation	1.0	1.4	3.1	1.1	1.4	1.1	1.8	1.0	0.8	0.3	1.4	0.9
Medication: Gliclazide	1.0	1.2	2.2	1.4	0.2	1.2	0.9	1.4	-0.5	1.2	0.4	1.5
Average weekly beer plus cider intake	1.0	1.5	3.0	-0.8	-0.2	-1.1	-1.7	-1.3	-1.5	-1.5	-0.7	-1.3
Smoking Status	0.9	2.3	4.5	-1.6	-1.3	-1.1	-1.1	-2.1	-1.0	-1.8	-1.1	-1.9
Angina	0.9	1.1	3.7	-0.7	-0.3	-0.7	-0.9	-1.6	0.5	-1.9	0.1	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	4.5	1.7	0.3	1.3	1.3	2.0	-0.5	1.9	0.3	2.1
Multivitamins +/- minerals	0.9	1.1	2.8	0.9	-1.1	0.8	0.3	1.4	-1.2	1.1	-0.3	1.7
Alcohol usually taken with meals	0.9	1.4	2.2	1.1	1.5	0.9	1.1	1.2	1.2	1.2	1.3	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.7	1.6	-0.0	1.0	1.3	2.2	-0.5	2.0	-0.1	2.1
Asthma	0.9	1.8	3.8	-1.6	-0.6	-1.9	-1.4	-1.2	-1.2	-1.0	-1.0	-1.4
Worry too long after embarrassment	0.9	1.5	3.3	0.7	1.1	0.3	1.8	1.7	0.9	0.6	1.4	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.7	-1.0	-0.6	-0.1	-1.0	-1.6	-1.3	-1.9	-0.7	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.0	-1.5	-0.2	-1.5	-0.8	-0.7	0.1	-0.7	-0.8	-1.7
Angina (self-reported)	0.9	1.2	3.9	-0.8	-0.6	-0.8	-1.0	-1.6	0.2	-2.0	-0.0	-1.3
Medication: Omeprazole	0.9	1.1	3.6	-0.5	-0.5	0.2	0.1	-1.6	1.1	-1.9	0.2	-1.1
Medication: Paracetamol	0.9	1.3	4.1	-0.5	-0.4	-0.6	-1.1	-2.0	-0.2	-1.6	-0.2	-1.9
Number of operations (self-reported)	0.9	1.3	3.4	-1.2	-1.4	-0.1	-0.6	-1.8	-0.1	-1.8	-0.5	-1.1
Risk taking	0.9	1.3	3.2	0.5	1.1	1.6	0.9	-1.2	1.8	-0.9	1.4	0.1
Commuting to job workplace: Cycle	0.9	1.1	3.5	-0.8	-1.2	-0.1	-0.9	-1.9	-0.5	-1.6	-0.4	-0.9
Coronary Artery Disease (CAD)	0.8	1.0	5.7	0.3	-0.2	0.3	-0.4	0.8	-2.4	0.9	-0.7	1.1
Blood White Count	0.8	6.0	14.4	-2.1	-1.6	-0.8	-3.8	-3.5	-2.6	-1.8	-1.7	-2.6
Allergy or Eczema	0.8	2.1	3.4	-1.4	-1.1	-1.8	-1.6	-1.6	-0.7	-1.3	-1.3	-1.9
Hearing difficulty/problems with background noise	0.8	1.3	3.9	0.9	1.8	0.1	1.1	0.5	2.0	0.5	1.5	0.1
Hair/balding pattern: Pattern 2	0.8	1.0	4.7	-1.1	-0.1	-2.2	-0.2	-0.1	0.5	-0.6	-1.1	-1.3
Tense / ‘highly strung’	0.8	1.2	3.6	-0.8	-1.4	-0.9	-1.1	-1.2	-0.9	-1.9	-0.3	-0.8
Medication: Amlodipine	0.8	1.2	2.2	-0.7	0.2	-1.1	-1.4	-1.5	-0.1	-0.6	-1.4	-1.5
Average weekly champagne plus white wine intake	0.8	1.1	3.4	0.7	-0.9	1.2	1.3	1.2	-0.7	0.5	0.5	1.9
Guilty feelings	0.8	1.2	2.2	0.7	1.0	0.9	1.5	1.2	-0.4	0.7	1.4	1.5
Hearing aid user	0.8	0.9	1.4	-0.9	-1.2	-1.2	-0.6	-1.0	1.0	-0.7	-0.6	-1.1
Medication: Atorvastatin	0.8	1.0	5.9	0.4	2.4	0.3	0.4	0.1	1.3	0.6	0.8	0.2
Age started oral contraceptive pill	0.8	1.1	3.2	-1.3	0.3	-1.4	-1.0	0.1	-1.8	-0.4	-0.9	-0.7
Reaction Time	0.7	1.3	2.3	-1.2	-1.3	-0.6	-1.5	-1.5	-0.8	-1.2	-0.7	-1.2
Body Mass Index (BMI) (2010)	0.7	1.0	2.8	0.7	1.7	0.9	1.4	0.3	1.5	0.1	0.6	0.3
Current tobacco smoking	0.7	1.1	2.8	1.1	0.1	1.2	1.7	0.5	1.5	0.8	0.9	0.8
Fed-up feelings	0.7	1.2	3.1	-0.7	-0.5	-0.9	-0.8	-1.5	0.9	-1.5	0.2	-1.8
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.3	-0.8	-1.1	-0.1	-0.9	-1.0	-1.5	-0.6	-1.1	-0.3
Qualifications: None of the above	0.7	1.5	4.5	-0.7	0.3	-1.0	-2.1	-1.9	-0.5	-1.0	-0.2	-1.6
Alcohol intake versus 10 years previously	0.7	1.1	4.0	-0.7	-1.0	-0.7	-0.8	-1.4	-0.6	-2.0	-0.3	-1.0
Number of live births	0.7	1.0	3.8	-0.8	-0.1	-1.1	-0.5	-1.0	-0.1	-2.0	0.0	-1.4
Happiness	0.7	0.8	2.1	0.9	-0.1	1.3	1.2	0.8	-0.2	0.5	0.6	1.4
Depression (self-reported)	0.7	0.9	4.3	0.6	0.2	0.5	0.9	-0.6	2.1	-1.0	0.8	-0.3
Headache pain in last month	0.7	1.3	2.6	1.0	1.0	1.6	1.4	1.0	0.5	0.9	0.9	1.4
Arm fat-free mass (right)	0.7	3.4	7.8	1.6	2.8	1.0	2.6	1.7	1.4	1.0	2.0	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.1	1.8	0.5	1.7	1.0	0.9	0.3	1.4	0.9	1.4
Asthma (self-reported)	0.7	1.4	2.8	-1.4	-0.4	-1.7	-1.3	-1.0	-1.4	-0.9	-1.0	-1.2
Wears glasses or contact lenses	0.7	0.9	2.0	-1.0	-0.9	-0.3	-1.3	-1.4	-0.6	-0.5	-0.6	-1.1
Ever depressed for a whole week	0.7	0.8	1.8	0.9	1.4	0.5	1.3	1.0	0.1	-0.4	0.7	1.1
Supplements: Calcium	0.7	0.8	1.9	0.7	1.1	0.4	0.9	1.4	-0.1	0.7	1.1	1.0
Arm predicted mass (left)	0.7	3.5	7.4	1.9	2.5	1.6	2.7	1.5	1.4	1.0	2.0	1.7
Mean Putamen Volume	0.6	0.7	2.4	-0.5	-1.5	0.7	-0.2	-1.4	-0.4	-0.4	-0.7	-0.3
HDL Cholesterol	0.6	1.0	1.9	1.1	1.1	0.9	0.5	1.1	-0.2	1.1	1.4	1.1
Height	0.6	10.9	24.0	3.6	0.3	2.9	2.9	4.9	-0.5	4.6	1.0	4.6
Respiratory disease	0.6	1.4	2.0	-1.2	-1.2	-1.2	-1.4	-1.4	-1.0	-1.0	-0.9	-1.2
Sensitivity / hurt feelings	0.6	0.9	2.2	0.6	0.7	0.5	1.3	0.6	1.5	-0.8	1.5	0.5
Townsend deprivation index at recruitment	0.6	0.9	2.6	0.7	0.5	1.1	0.9	-0.3	1.2	-0.9	1.6	0.5
Sitting height	0.6	4.1	9.9	2.0	-0.1	1.6	1.4	3.1	-1.2	2.7	0.1	3.0
Hip circumference	0.6	2.8	6.9	1.2	2.6	1.2	2.6	0.6	2.1	-0.3	1.6	0.8
Hair/balding pattern: Pattern 3	0.6	0.9	2.3	1.3	0.8	1.5	0.4	0.5	0.8	0.9	0.7	1.0
Pulse wave reflection index	0.6	0.7	1.4	-0.7	-0.3	-1.1	-0.8	-1.0	-0.6	-0.8	-0.8	-1.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.6	-0.1	0.2	-0.5	-0.8	0.6	-1.6	1.6	-0.7	0.1
Leg fat percentage (right)	0.6	2.3	5.3	0.9	2.3	0.8	2.1	0.3	2.1	-0.4	2.0	0.5
Mean time to correctly identify matches	0.6	1.2	3.4	-1.2	-0.9	-0.5	-1.3	-1.8	-0.2	-1.4	-0.3	-1.3
Arm predicted mass (right)	0.6	3.2	6.6	1.7	2.6	1.1	2.6	1.7	1.1	0.9	2.0	1.5
Supplements: Vitamin C	0.6	0.8	2.3	-0.2	-1.1	0.4	-1.2	-1.5	-0.6	-0.9	-0.3	-0.5
Knee pain experienced in last month	0.6	0.9	2.8	-0.3	-1.7	0.3	-0.5	-1.5	0.9	-0.8	-0.8	-0.6
Illnesses of siblings: Diabetes	0.6	0.7	1.5	-1.0	-0.7	-1.1	-0.4	-0.9	-0.1	-1.2	-0.3	-1.1
Friendships satisfaction	0.6	0.8	1.7	0.8	0.7	1.3	1.3	-0.1	0.9	-0.3	1.1	0.5
Back pain experienced in last month	0.6	0.9	2.7	1.1	0.1	1.6	0.8	0.4	-0.1	0.1	0.9	1.5
Arm fat-free mass (left)	0.6	3.2	6.9	1.7	2.4	1.4	2.6	1.5	1.2	0.9	2.0	1.6
Cholesterol lowering medication	0.6	0.9	4.0	0.1	2.0	0.2	0.2	-0.9	1.4	-0.2	1.2	-0.5
Worry (Nagel 2018)	0.5	1.0	3.9	-0.2	-0.8	-0.9	-0.5	-1.3	0.4	-2.0	0.6	-1.0
Major Depression (MDD)	0.5	0.6	1.9	-0.8	-0.1	-1.2	-0.8	0.2	-1.4	-0.7	-0.8	-0.2
Neuroticism	0.5	1.3	3.6	-0.5	-0.6	-1.0	-1.0	-1.7	0.5	-1.9	0.6	-1.4
Impedance of leg (right)	0.5	2.4	6.1	1.9	-0.8	1.4	0.3	2.0	-0.6	2.5	1.2	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.9	0.0	0.4	0.6	0.9	-0.9	1.4	-1.2	1.1	-0.5
Taking other prescription medications	0.5	0.8	3.2	-1.0	-0.2	-0.4	-0.6	-1.8	0.4	-0.8	-0.6	-1.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.4	0.1	-0.7	0.6	-0.3	0.3	-1.5	0.7	-0.4	1.0
Body mass index (BMI)	0.5	2.2	6.8	0.1	2.6	0.2	1.9	-0.6	2.2	-1.6	1.4	-0.3
Weight	0.5	2.4	6.4	1.2	2.4	0.9	2.5	1.1	1.6	0.0	1.5	1.2
Impedance of arm (right)	0.5	2.4	9.4	-0.6	-3.1	-0.5	-1.9	-0.3	-2.0	-0.3	-1.8	-0.1
Trunk fat-free mass	0.5	2.8	5.7	1.7	2.0	1.5	2.4	1.5	1.1	1.2	1.7	1.6
Lung cancer (father)	0.5	0.5	1.1	-0.8	-0.6	-1.1	-0.8	-0.7	0.2	-0.4	-0.7	-0.9
Trunk predicted mass	0.5	2.8	5.7	1.7	2.0	1.5	2.4	1.5	1.2	1.1	1.7	1.6
Standing height	0.5	5.3	12.7	2.6	-0.1	1.8	1.8	3.6	-0.9	3.3	0.5	3.2
Age at first live birth	0.5	0.9	3.0	-0.6	-0.5	-1.0	-1.5	0.3	-1.7	0.4	-1.1	-0.2
Leg fat mass (right)	0.5	1.8	6.0	0.7	2.4	0.7	1.9	0.3	1.6	-0.5	1.7	0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	1.9	0.7	-0.1	1.2	1.4	0.6	0.0	0.6	0.5	1.0
Commuting to job workplace: Public transport	0.5	0.6	1.5	1.0	-0.5	1.2	0.3	-0.0	1.0	0.0	0.8	0.8
High cholesterol (Self-reported)	0.5	0.8	2.4	-0.9	0.4	-0.9	-1.3	-1.5	0.1	-0.7	-0.7	-0.9
Basal metabolic rate	0.5	2.8	6.1	1.6	2.3	1.3	2.5	1.4	1.2	0.8	1.7	1.6
Leg fat percentage (left)	0.5	1.8	4.5	0.6	2.1	0.7	2.1	0.2	1.8	-0.6	1.7	0.5
Alcohol drinker status: Previous	0.5	0.5	2.5	0.6	-0.8	1.6	-0.5	-0.8	-0.5	-0.2	-0.1	0.2
Ulcerative Colitis (UC)	0.4	0.8	2.5	1.5	-0.2	1.6	0.2	0.4	0.2	1.1	0.8	0.9
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.7	-0.5	0.7	-1.2	1.3	1.2	1.2	0.8	-0.5	-0.1
Fasting Glucose	0.4	0.5	1.5	-0.3	-1.2	-0.2	-0.8	-0.5	-0.9	-0.6	-0.9	0.2
Schizophrenia (2014)	0.4	0.8	1.8	1.0	0.4	1.2	1.3	0.6	1.0	0.2	1.0	0.8
Blood Platelet Count	0.4	4.7	10.2	-1.9	-3.2	-0.6	-2.0	-2.2	-2.8	-1.8	-2.7	-0.8
Blood Red Count	0.4	4.0	7.0	-2.1	-2.1	-1.7	-2.2	-1.5	-2.5	-1.4	-2.6	-1.4
Waist Hip Ratio (WHR)	0.4	1.6	4.6	-1.2	-0.5	-1.3	-2.1	-0.1	-2.1	1.0	-0.8	-0.9
Number of treatments/medications taken	0.4	0.8	3.1	-0.5	-0.8	-0.2	-1.2	-1.8	-0.5	-0.4	-0.4	-0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.6	3.3	-0.1	-0.5	0.4	-0.6	-0.7	-0.5	-1.8	-0.5	-0.1
Vitamin and mineral supplements	0.4	0.5	2.2	0.1	1.0	0.1	0.8	0.1	1.5	0.5	0.4	-0.4
Stomach or abdominal pain in last month	0.4	0.5	1.2	-0.5	0.2	0.6	0.5	-1.0	1.1	-1.1	0.4	-0.7
Impedance of leg (left)	0.4	1.7	4.3	1.2	-1.2	1.1	-0.0	1.8	-1.4	2.1	0.4	1.5
Trunk fat mass	0.4	1.8	4.4	1.0	1.9	0.9	2.1	0.8	1.5	-0.2	1.4	1.1
Heart attack	0.4	0.5	2.5	0.3	-0.0	-0.1	-0.1	-0.4	1.6	-1.1	-0.1	-0.5
Allergy	0.4	1.0	1.5	0.9	0.9	1.1	1.0	0.8	1.2	1.2	0.9	0.7
Father’s age at death	0.4	0.6	1.5	-1.2	-0.9	-0.8	-0.5	-0.4	-1.1	-0.4	-0.3	-0.5
Worrier / anxious feelings	0.4	0.7	1.8	1.0	1.2	-0.0	0.5	-0.3	1.1	-0.8	1.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.0	-0.4	0.1	0.4	-0.1	-1.4	-0.1	-1.3	-0.1	-0.5
Impedance of arm (left)	0.4	1.6	6.6	-0.6	-2.6	-0.9	-1.4	0.3	-1.5	0.1	-1.6	-0.1
Arm fat mass (right)	0.4	1.5	4.2	0.4	2.0	0.5	1.8	-0.3	1.7	-1.2	1.1	0.2
Exposure to tobacco smoke at home	0.4	0.4	1.0	-0.7	-0.3	-0.1	-0.9	-1.0	-0.2	-0.9	0.1	-0.9
Gout (self-reported)	0.4	0.6	2.8	-0.6	-0.2	-0.8	-0.7	-0.6	-0.4	0.3	-1.7	-0.5
Eye problems/disorders: None of the above	0.4	0.5	1.5	0.8	1.2	0.5	0.1	-0.1	0.7	-0.6	1.0	0.4
Neck or shoulder pain in last month	0.4	0.6	1.8	0.8	1.3	0.9	0.1	-0.6	1.3	0.2	0.5	-0.3
Whole body fat mass	0.4	1.7	4.5	0.9	2.1	0.7	1.9	0.5	1.6	-0.5	1.4	0.7
Suffer from ‘nerves’	0.4	0.7	1.9	0.9	0.3	0.8	1.1	0.3	1.4	0.2	1.0	0.4
Overall health rating	0.4	0.8	2.7	0.2	-0.8	0.9	-0.5	-1.6	0.4	-1.7	0.4	-0.4
Age at last live birth	0.4	0.6	1.2	-0.9	-1.0	-1.1	-0.8	-0.2	-0.8	-0.5	-0.8	-0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.0	-1.0	0.6	-0.5	-0.5	-0.4	-0.9	-0.3	-0.5	-0.8
Illnesses of father: Heart disease	0.4	0.6	1.9	0.1	0.6	-1.1	-1.4	-0.6	0.0	-0.2	-0.7	-0.8
Whole body fat-free mass	0.4	2.5	5.2	1.6	2.1	1.3	2.3	1.4	1.1	0.9	1.6	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.2	0.3	-0.4	1.1	0.3	-0.8	0.7	-1.0	1.0	0.0
Osteoporosis (self-reported)	0.4	0.5	1.4	0.9	0.5	1.2	0.2	0.4	0.2	0.1	1.1	0.7
Whole body water mass	0.4	2.4	5.0	1.5	2.1	1.2	2.2	1.4	1.1	0.8	1.5	1.5
Arm fat mass (left)	0.4	1.7	4.9	0.4	2.2	0.2	1.9	-0.2	2.0	-1.2	1.2	0.0
Ever taken oral contraceptive pill	0.4	0.5	1.7	-0.8	-0.2	-0.6	0.1	-0.3	1.3	-0.7	0.6	-0.8
Pack years of smoking	0.4	0.6	1.2	-0.3	1.1	-0.9	-0.7	-0.7	0.6	-1.0	-0.2	-1.1
Leg fat mass (left)	0.4	1.7	5.5	0.6	2.4	0.7	1.9	0.3	1.4	-0.5	1.5	0.5
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.0	0.5	0.6	0.3	1.4	1.4	0.7	0.8	0.1	1.1
Neuroticism (Nagel 2018)	0.3	0.7	2.4	-0.5	-0.5	-0.4	-0.2	-1.2	0.4	-1.5	0.5	-1.1
Bipolar Disorder (2011)	0.3	0.3	1.5	0.2	0.0	0.6	-0.5	0.4	-1.2	0.6	0.1	0.5
HbA1C	0.3	0.3	1.7	0.5	-0.2	-0.3	0.7	0.1	1.3	0.2	-0.1	-0.1
Neuroticism (2016)	0.3	0.5	0.9	1.0	0.6	-0.0	0.8	0.9	0.9	0.2	0.8	0.4
Primary Biliary Cirrhosis	0.3	0.5	1.2	0.8	-0.2	1.0	-0.0	0.6	0.2	1.1	0.4	0.9
Rheumatoid Arthritis	0.3	0.4	1.2	-0.0	-0.9	0.2	-0.1	0.8	-1.1	0.5	-0.1	0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.4	0.2	0.3	0.2	0.0	0.7	-0.3	0.6	0.6	1.2
Heel T-Score	0.3	2.5	6.0	1.8	-0.3	1.7	1.3	2.0	-0.7	2.5	-0.4	2.1
BMI	0.3	1.9	8.1	-0.3	2.9	0.4	1.2	-1.0	1.4	-1.8	0.9	-0.5
Lung FEV1/FVC ratio	0.3	1.5	3.9	0.2	1.9	0.0	1.9	0.7	1.2	-0.3	2.0	0.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.1	-0.3	0.0	0.5	0.4	-0.8	0.8	-1.1	0.5	-0.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.0	-0.3	-1.0	0.5	-0.4	-0.5	-0.5	-1.0	-0.2	0.3
Pack years adult smoking proportion	0.3	0.5	1.6	-0.2	1.3	-0.5	-0.3	-0.5	0.8	-0.9	0.2	-1.0
Leg fat-free mass (left)	0.3	1.5	3.8	1.0	1.9	0.8	1.8	0.9	1.1	0.0	1.1	1.1
Trunk fat percentage	0.3	1.2	2.8	0.7	1.6	0.5	1.7	0.5	1.4	-0.6	1.1	0.7
Supplements: Glucosamine	0.3	0.4	1.1	1.1	0.9	0.7	-0.1	0.1	-0.2	0.0	0.9	0.4
Leg predicted mass (left)	0.3	1.5	3.8	1.1	1.9	0.8	1.8	0.9	1.1	0.1	1.1	1.1
Waist circumference	0.3	0.9	4.1	0.2	2.0	0.2	1.1	-0.1	1.3	-0.4	1.1	-0.0
Had menopause	0.3	0.4	1.1	-0.5	-0.1	-1.0	-0.6	-0.5	0.0	-0.2	-0.9	-1.0
Neuroticism score	0.3	0.5	2.6	-0.4	-0.0	-0.5	-0.3	-0.9	0.0	-1.6	0.5	-0.8
Arm fat percentage (right)	0.3	1.2	3.1	0.1	1.4	0.3	1.4	-0.6	1.8	-1.6	0.9	-0.1
Falls in the last year	0.3	0.4	0.9	0.1	-0.6	0.7	-0.8	-1.0	-0.0	-0.4	-0.7	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.9	0.7	0.4	0.9	0.2	0.1	0.7	-0.3	0.9	0.1
Peak expiratory flow (PEF)	0.3	0.7	2.6	-0.6	-1.6	-1.6	0.4	0.1	-0.4	-0.3	-0.6	-0.3
Blood clot in the leg (DVT)	0.3	0.4	1.2	0.2	-1.1	0.1	1.1	0.1	0.1	-0.4	-0.9	0.1
Medication: Paracetamol	0.3	0.5	0.9	0.4	0.7	0.0	-0.2	-1.0	0.5	-0.6	1.0	-0.9
Glaucoma (self-reported)	0.3	0.4	2.0	-0.4	0.5	-0.3	-0.4	-0.4	0.5	-0.5	1.4	-0.6
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.0	0.2	1.0	-0.1	-0.6	0.5	-0.8	0.8	0.3	-0.2
Body fat percentage	0.3	1.3	3.5	0.5	1.9	0.5	1.8	0.3	1.5	-0.6	1.3	0.5
Family relationship satisfaction	0.3	0.4	2.4	0.6	-0.3	1.5	0.4	-0.0	-0.3	-0.1	-0.0	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	0.2	0.0	0.4	0.4	0.2	1.3	0.5	0.6	0.1
Arm fat percentage (left)	0.3	1.4	3.5	-0.0	1.7	-0.0	1.5	-0.6	1.9	-1.6	1.0	-0.3
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.7	-0.4	0.7	-0.6	0.5	0.8	0.2	1.3	0.0	0.2
Ever had bowel cancer screening	0.3	0.4	1.7	-0.2	-1.3	-0.3	-0.5	-0.8	0.4	-0.6	-0.5	-0.3
Qualifications: nursing, teaching	0.3	0.5	1.7	0.1	-0.7	-0.1	1.3	0.7	1.3	0.2	0.4	0.3
Breast cancer (self-reported)	0.3	0.4	0.7	-0.6	-0.8	-0.2	-0.8	-0.7	0.3	0.0	-0.8	-0.8
Smoking status: Current	0.3	0.5	1.3	0.7	-0.4	0.8	1.1	0.3	0.8	0.5	0.3	0.6
Financial situation satisfaction	0.3	0.4	1.6	0.9	-0.1	1.3	0.4	-0.4	0.1	-0.3	0.5	0.5
Fractured/broken bones in last 5 years	0.3	0.4	1.4	1.2	-0.0	1.1	-0.1	0.2	-0.1	0.5	0.3	0.7
Myopia	0.3	0.5	1.5	0.8	-0.2	1.2	0.5	0.5	0.7	0.3	0.7	0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.1	0.6	-0.1	-0.0	0.0	-0.1	1.5	-1.0	0.1	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.8	0.7	-0.6	0.7	1.3	0.2	0.6	-0.2	-0.2	0.3
Impedance of whole body	0.3	1.3	4.0	0.4	-2.0	0.1	-0.9	1.2	-1.8	1.1	-0.7	0.8
Crohns Disease (2017)	0.2	0.4	2.0	-0.1	-0.4	-0.7	-0.5	-0.7	-0.0	0.1	-1.4	-0.5
Hand grip strength (left)	0.2	0.6	1.5	0.0	0.3	-0.3	1.2	1.1	-0.2	1.2	-0.5	0.7
Medication for hormone replacement therapy	0.2	0.2	1.0	0.3	0.3	1.0	0.3	-0.1	-0.0	0.3	-0.1	0.6
Supplements: Zinc	0.2	0.2	0.7	0.2	-0.8	0.1	0.7	0.4	-0.2	0.3	-0.3	0.1
Average weekly fortified wine intake	0.2	0.3	1.1	0.2	0.2	0.5	-0.6	-1.0	0.5	-0.5	-0.1	-0.4
Qualifications: CSEs or equivalent	0.2	0.2	0.9	-0.4	-0.7	-0.0	0.1	-0.2	0.1	-0.9	-0.4	-0.6
Number of incorrect matches in round	0.2	0.3	0.6	0.6	-0.3	0.7	0.8	0.0	0.6	-0.1	0.8	0.3
Nervous feelings	0.2	0.3	1.8	0.3	0.1	-0.4	0.5	0.1	-0.3	-1.3	0.4	0.0
Had other major operations	0.2	0.2	1.1	0.4	0.2	0.2	0.5	-0.2	0.3	-1.0	0.1	0.1
Fluid intelligence score	0.2	0.4	1.1	-0.5	0.8	-0.6	0.5	0.4	0.4	0.6	-1.0	-0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	-0.9	-1.1	-1.2	-0.5	-0.1	-0.2	-0.1	-0.9	-0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.5	-0.3	0.3	-0.2	0.5	0.0	0.6	-0.6	0.7	-0.0
Exposure to tobacco smoke outside home	0.2	0.2	0.5	0.1	-0.5	0.5	0.2	0.1	0.7	0.7	-0.5	0.2
Shortness of breath walking on level ground	0.2	0.3	0.8	-0.5	-0.6	-0.0	0.3	-0.7	-0.7	-0.9	-0.3	0.2
Medication: Ibuprofen	0.2	0.2	0.6	0.8	0.4	0.7	-0.0	0.4	-0.2	0.0	0.6	0.2
Pulse rate, automated reading	0.2	0.6	1.6	-1.2	-0.3	-1.3	-0.2	-0.3	-0.5	-0.6	0.8	-0.8
Alcohol intake frequency.	0.2	0.4	0.7	0.7	-0.4	0.9	0.3	0.4	0.7	0.8	0.2	0.7
Number of full sisters	0.2	0.3	1.3	0.5	-0.5	1.2	0.4	-0.2	0.6	0.4	-0.2	0.4
Medication: Aspirin	0.2	0.3	1.1	0.4	0.1	0.1	-0.7	-1.0	-0.1	-0.5	-0.1	-0.4
Leg fat-free mass (right)	0.2	0.8	2.4	0.6	1.6	0.6	1.6	0.7	0.7	-0.1	0.6	0.9
Commuting to job workplace: Walk	0.2	0.3	1.3	-0.3	-0.6	-1.1	-0.0	-0.0	0.5	-0.1	-0.4	-0.5
Mineral and other dietary supplements	0.2	0.3	0.6	-0.8	0.6	-0.6	0.2	0.1	0.7	0.1	-0.5	-0.4
Medication: Aspirin	0.2	0.3	1.2	0.4	0.1	0.1	-0.7	-1.1	-0.3	-0.8	-0.2	-0.4
Eye problems/disorders: Glaucoma	0.2	0.3	1.1	-0.5	0.3	-0.4	-0.7	0.2	-0.3	-0.3	1.0	-0.2
Alcohol drinker status: Never	0.2	0.3	0.9	0.5	-0.6	0.6	0.3	0.2	0.3	0.9	-0.2	0.6
Irritability	0.2	0.3	0.9	-0.1	0.3	0.4	-0.8	-0.5	-0.9	-0.5	0.4	-0.1
Bipolar Disorder (2018)	0.1	0.1	0.4	-0.0	-0.2	-0.3	0.2	0.4	0.3	0.3	0.6	0.1
Bipolar Disorder or Schizophrenia	0.1	0.1	0.4	0.3	-0.0	0.2	0.3	-0.0	0.6	-0.3	0.7	-0.0
Schizophrenia (2018)	0.1	0.2	0.5	0.4	0.1	0.6	0.1	-0.4	0.6	-0.7	0.4	-0.1
Schizophrenia vs Biploar Disorder	0.1	0.2	0.3	0.5	0.3	0.5	0.5	-0.2	0.4	-0.5	-0.2	0.1
Irritable Bowel Disease (IBD)	0.1	0.4	1.0	1.0	-0.6	0.6	-0.2	0.2	-0.2	1.0	-0.4	0.5
Prostate Cancer	0.1	0.2	0.7	0.9	0.8	0.2	-0.3	-0.0	0.1	0.3	-0.1	0.4
Age at First Birth	0.1	0.2	0.7	0.2	-0.1	0.9	-0.3	-0.1	-0.1	-0.5	0.2	0.6
Crohns Disease (2012)	0.1	0.1	0.4	0.4	0.5	0.1	0.0	0.4	-0.6	0.1	0.0	0.5
Hair Pigment	0.1	1.9	6.1	-0.8	-2.0	0.0	-1.3	-1.0	-2.5	-0.5	-1.9	-0.3
Tanning	0.1	1.0	3.5	1.4	0.6	1.4	0.4	0.0	1.9	0.2	1.0	0.5
Hearing difficulty/problems: Yes	0.1	0.1	0.4	0.3	-0.2	0.1	0.2	0.3	0.6	0.5	0.3	0.4
Hand grip strength (right)	0.1	0.4	1.1	-0.3	-0.6	-1.1	0.5	0.6	-0.1	0.4	-0.9	-0.0
Relative age voice broke	0.1	0.2	1.0	-0.3	-0.2	1.0	0.4	-0.3	-0.2	0.2	0.5	0.3
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.8	-0.5	-0.6	-0.7	-0.9	-0.3	-0.4	-0.3	-0.5	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	0.4	0.1	0.8	0.8	-0.1	0.5	-0.4	0.4	0.2
Pulse rate	0.1	0.1	0.4	-0.3	0.4	0.3	0.2	-0.5	0.4	-0.4	0.6	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	-0.5	-0.4	-0.1	-0.1	-0.4	0.5	0.4	-0.3	-0.5
Breastfed as a baby	0.1	0.1	0.3	0.4	0.3	0.4	-0.4	0.3	-0.3	0.2	0.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.4	0.1	0.7	-0.3	-0.0	0.2	-0.2	-0.3	0.2	-0.2
Comparative body size at age 10	0.1	0.4	1.3	-0.5	0.1	-0.7	1.1	0.7	0.1	-0.7	-0.5	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.4	-0.5	0.3	0.0	0.2	-0.6	0.5	-0.3	0.4	-0.5
Long-standing illness, disability or infirmity	0.1	0.2	0.7	-0.4	-0.6	0.1	-0.1	-0.7	-0.2	-0.8	-0.4	-0.1
Leg predicted mass (right)	0.1	0.8	2.2	0.6	1.5	0.6	1.5	0.7	0.6	-0.1	0.5	0.9
Mother’s age at death	0.1	0.2	0.9	-0.1	-1.0	-0.4	0.1	0.2	0.1	-0.2	-0.5	-0.0
Heart disease (siblings)	0.1	0.1	0.4	-0.3	0.3	-0.6	-0.1	-0.2	0.1	-0.4	0.3	-0.4
Triglycerides	0.0	0.1	0.2	0.1	0.1	-0.4	0.5	0.3	-0.2	-0.2	-0.3	0.1

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