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chr16:74,635,632-76,197,034

Best TWAS P=8.77e-10 · Best GWAS P=1.61e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Cortex	CFDP1	0.18	0.07	lasso	3	0.08	3.4e-03	-6.0	-6.1	8.8e-10	0.98	0.01	0.93	TRUE
9	GTEx	Nerve Tibial	CFDP1	0.16	0.14	lasso	3	0.12	1.6e-08	-5.9	-6.0	2.0e-09	0.96	0.00	1.00	FALSE
3	GTEx	Breast Mammary Tissue (Female)	CFDP1	0.07	0.05	lasso	1	0.05	1.5e-02	-6.0	-6.0	2.5e-09	1.00	0.01	0.86	FALSE
7	GTEx	Esophagus Muscularis	CFDP1	0.18	0.12	lasso	5	0.09	3.1e-06	-6.0	-6.0	2.5e-09	1.00	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	CFDP1	0.11	0.09	lasso	2	0.09	1.1e-07	-5.9	-5.9	3.4e-09	0.98	0.01	0.99	FALSE
5	GTEx	Colon Transverse	CFDP1	0.14	0.11	lasso	2	0.08	7.6e-05	-6.0	-5.9	4.0e-09	1.00	0.00	0.99	FALSE
8	GTEx	Muscle Skeletal	CFDP1	0.05	0.05	enet	4	0.04	3.4e-05	-5.8	-5.9	4.3e-09	0.98	0.01	0.99	FALSE
10	GTEx	Pancreas	CFDP1	0.16	0.07	lasso	2	0.12	1.2e-05	-6.0	-5.8	8.5e-09	0.96	0.00	0.99	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	CFDP1	0.04	0.03	enet	10	0.03	5.2e-07	-5.9	-5.7	1.1e-08	0.93	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	CFDP1	0.04	0.02	lasso	6	0.03	4.0e-04	-5.5	-5.7	1.1e-08	0.92	0.03	0.96	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CFDP1	0.02	0.02	lasso	4	0.02	1.9e-03	-4.7	-5.5	3.4e-08	0.78	0.03	0.83	FALSE
16	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CFDP1	0.23	0.00	blup	70	0.02	4.2e-02	-5.4	-5.5	3.6e-08	0.83	0.01	0.68	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CFDP1	0.03	0.00	blup	71	0.01	1.1e-02	-5.4	-5.5	4.2e-08	0.94	0.01	0.92	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CFDP1	0.10	0.00	blup	70	0.04	1.4e-02	-4.7	-5.4	5.4e-08	0.87	0.02	0.60	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	CFDP1	0.31	0.17	lasso	4	0.16	3.0e-06	-5.4	-5.3	1.3e-07	0.95	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	CFDP1	0.06	0.05	enet	6	0.05	3.2e-06	-6.0	-5.3	1.4e-07	0.96	0.00	1.00	FALSE
11	METSIM	Adipose	TMEM170A	0.03	0.01	lasso	3	0.02	1.5e-03	-4.6	-5.3	1.5e-07	0.71	0.16	0.82	FALSE
4	GTEx	Cells Transformed fibroblasts	CFDP1	0.17	0.20	enet	10	0.24	9.9e-18	-4.6	-5.2	1.7e-07	0.72	0.76	0.23	FALSE