Best TWAS P=8.77e-10 · Best GWAS P=1.61e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CFDP1 | 0.11 | 0.09 | lasso | 2 | 0.09 | 1.1e-07 | -5.9 | -5.9 | 3.4e-09 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Cortex | CFDP1 | 0.18 | 0.07 | lasso | 3 | 0.08 | 3.4e-03 | -6.0 | -6.1 | 8.8e-10 | 0.98 | 0.01 | 0.93 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Female) | CFDP1 | 0.07 | 0.05 | lasso | 1 | 0.05 | 1.5e-02 | -6.0 | -6.0 | 2.5e-09 | 1.00 | 0.01 | 0.86 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | CFDP1 | 0.17 | 0.20 | enet | 10 | 0.24 | 9.9e-18 | -4.6 | -5.2 | 1.7e-07 | 0.72 | 0.76 | 0.23 | FALSE |
| 5 | GTEx | Colon Transverse | CFDP1 | 0.14 | 0.11 | lasso | 2 | 0.08 | 7.6e-05 | -6.0 | -5.9 | 4.0e-09 | 1.00 | 0.00 | 0.99 | FALSE |
| 6 | GTEx | Esophagus Gastroesophageal Junction | CFDP1 | 0.31 | 0.17 | lasso | 4 | 0.16 | 3.0e-06 | -5.4 | -5.3 | 1.3e-07 | 0.95 | 0.01 | 0.99 | FALSE |
| 7 | GTEx | Esophagus Muscularis | CFDP1 | 0.18 | 0.12 | lasso | 5 | 0.09 | 3.1e-06 | -6.0 | -6.0 | 2.5e-09 | 1.00 | 0.00 | 1.00 | FALSE |
| 8 | GTEx | Muscle Skeletal | CFDP1 | 0.05 | 0.05 | enet | 4 | 0.04 | 3.4e-05 | -5.8 | -5.9 | 4.3e-09 | 0.98 | 0.01 | 0.99 | FALSE |
| 9 | GTEx | Nerve Tibial | CFDP1 | 0.16 | 0.14 | lasso | 3 | 0.12 | 1.6e-08 | -5.9 | -6.0 | 2.0e-09 | 0.96 | 0.00 | 1.00 | FALSE |
| 10 | GTEx | Pancreas | CFDP1 | 0.16 | 0.07 | lasso | 2 | 0.12 | 1.2e-05 | -6.0 | -5.8 | 8.5e-09 | 0.96 | 0.00 | 0.99 | FALSE |
| 11 | METSIM | Adipose | TMEM170A | 0.03 | 0.01 | lasso | 3 | 0.02 | 1.5e-03 | -4.6 | -5.3 | 1.5e-07 | 0.71 | 0.16 | 0.82 | FALSE |
| 12 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CFDP1 | 0.04 | 0.03 | enet | 10 | 0.03 | 5.2e-07 | -5.9 | -5.7 | 1.1e-08 | 0.93 | 0.00 | 1.00 | FALSE |
| 13 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CFDP1 | 0.02 | 0.02 | lasso | 4 | 0.02 | 1.9e-03 | -4.7 | -5.5 | 3.4e-08 | 0.78 | 0.03 | 0.83 | FALSE |
| 14 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CFDP1 | 0.03 | 0.00 | blup | 71 | 0.01 | 1.1e-02 | -5.4 | -5.5 | 4.2e-08 | 0.94 | 0.01 | 0.92 | FALSE |
| 15 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CFDP1 | 0.04 | 0.02 | lasso | 6 | 0.03 | 4.0e-04 | -5.5 | -5.7 | 1.1e-08 | 0.92 | 0.03 | 0.96 | FALSE |
| 16 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CFDP1 | 0.23 | 0.00 | blup | 70 | 0.02 | 4.2e-02 | -5.4 | -5.5 | 3.6e-08 | 0.83 | 0.01 | 0.68 | FALSE |
| 17 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CFDP1 | 0.06 | 0.05 | enet | 6 | 0.05 | 3.2e-06 | -6.0 | -5.3 | 1.4e-07 | 0.96 | 0.00 | 1.00 | FALSE |
| 18 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | CFDP1 | 0.10 | 0.00 | blup | 70 | 0.04 | 1.4e-02 | -4.7 | -5.4 | 5.4e-08 | 0.87 | 0.02 | 0.60 | FALSE |