TWAS hub - TMEM170A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1080	0.0390	5.6e-04	0.004	NA	0.004	NA	0.008	1.4e-01	NA	1.4e-01	NA	6.7e-02
2	GTEx	Adrenal Gland	0.1075	0.0485	9.5e-03	0.063	NA	0.037	NA	0.000	2.7e-03	NA	1.7e-02	NA	3.2e-01
3	GTEx	Cells EBV-transformed lymphocytes	0.1330	0.0640	9.4e-03	0.066	NA	-0.005	NA	0.022	3.5e-03	NA	5.0e-01	NA	6.2e-02
4	GTEx	Muscle Skeletal	0.0778	0.0297	9.0e-04	0.003	NA	0.002	NA	0.000	1.5e-01	NA	1.9e-01	NA	3.6e-01
5	GTEx	Nerve Tibial	0.1166	0.0413	3.1e-05	0.086	NA	0.109	NA	0.105	1.1e-06	NA	4.1e-08	NA	6.7e-08
6	GTEx	Skin Not Sun Exposed Suprapubic	0.0920	0.0400	3.4e-03	0.024	NA	0.024	NA	0.049	1.8e-02	NA	1.7e-02	NA	1.1e-03
7	GTEx	Skin Sun Exposed Lower leg	0.1350	0.0430	1.1e-05	0.083	NA	0.055	NA	0.059	2.2e-07	NA	2.4e-05	NA	1.2e-05
8	GTEx	Thyroid	0.0900	0.0360	2.5e-03	0.018	NA	-0.003	NA	-0.001	1.5e-02	NA	7.1e-01	NA	4.0e-01
9	METSIM	Adipose	0.0346	0.0152	1.9e-03	0.011	0.013	0.013	NA	0.016	7.0e-03	3.8e-03	3.4e-03	NA	1.5e-03
10	YFS	Blood	0.0287	0.0133	5.2e-03	0.022	0.003	0.016	0.013	0.018	8.9e-08	3.0e-02	4.9e-06	2.1e-05	1.2e-06
11	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0820	0.0350	1.1e-06	0.097	0.128	0.106	NA	0.110	3.2e-06	9.1e-08	1.1e-06	NA	7.4e-07
12	TCGA	Thyroid Carcinoma	0.1360	0.0500	1.3e-04	0.017	0.046	0.042	NA	0.049	7.1e-03	2.5e-05	5.8e-05	NA	1.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12
Lung FEV1/FVC ratio	34.2	173.7	343.3	16.3	-18.5	13.5	16.9	-9.0	-12.0	12.5	16.8	6.9	17.1	2.0
Systolic Blood Pressure	11.6	58.1	116.6	-8.5	10.8	-8.3	-9.7	6.0	7.9	-6.7	-9.6	-3.2	-10.0	0.1
Headache pain in last month	8.8	15.2	29.9	3.7	-5.4	4.4	5.5	-3.3	-4.5	3.9	4.6	1.3	4.7	-0.2
Birth weight of first child	8.2	14.8	27.9	4.6	-5.3	3.7	5.2	-2.2	-3.2	4.4	4.8	1.9	5.1	1.0
Systolic blood pressure, automated reading	7.8	22.8	43.9	-5.5	6.6	-5.0	-6.3	4.1	4.8	-4.2	-6.0	-1.4	-6.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.6	16.1	30.5	5.3	-5.5	3.3	5.4	-2.3	-3.2	4.7	5.3	2.6	4.5	1.7
Coronary Artery Disease (CAD)	7.3	8.7	16.3	-2.8	3.8	-3.6	-3.1	3.9	3.6	-1.5	-3.4	-0.8	-4.0	0.5
High blood pressure (mother)	6.9	9.7	21.4	-3.6	4.6	-3.0	-4.2	1.6	2.3	-3.4	-4.1	-1.5	-4.1	-0.6
Peak expiratory flow (PEF)	6.2	14.5	28.7	4.1	-5.4	4.2	5.2	-2.5	-3.7	3.7	4.8	1.4	4.9	0.0
Heart disease (siblings)	6.1	7.5	15.4	-2.6	3.8	-2.8	-3.1	2.8	3.0	-1.4	-3.9	-1.8	-3.7	-0.1
Ulcerative Colitis	5.8	8.4	19.4	2.4	-3.8	3.6	3.1	-3.8	-3.3	1.1	3.2	0.7	4.4	-1.3
Pulse wave peak to peak time	5.8	6.8	13.7	-1.9	3.2	-3.3	-3.3	2.5	3.7	-2.6	-1.8	1.2	-3.1	1.9
Allergy or Eczema	5.0	13.2	29.9	3.1	-4.8	4.2	3.9	-4.8	-4.2	2.0	4.0	0.7	5.5	-1.4
Pulse wave Arterial Stiffness index	4.8	5.6	12.2	1.7	-2.9	3.0	3.0	-2.3	-3.5	2.5	1.5	-1.3	2.7	-1.9
Emphysema/chronic bronchitis	4.8	5.4	12.1	-2.8	3.1	-2.1	-2.7	1.1	2.1	-1.9	-3.5	-2.0	-2.9	-1.2
Angina	4.2	5.6	11.3	-2.1	3.4	-2.5	-3.1	1.5	2.9	-1.9	-3.3	-1.6	-2.7	-0.4
Hayfever, allergic rhinitis or eczema	4.2	9.1	19.2	2.4	-4.1	3.5	3.5	-3.7	-3.6	2.2	3.0	0.1	4.4	-1.4
Mouth/teeth dental problems: Loose teeth	4.2	4.9	9.1	0.0	-2.1	2.9	2.6	-3.0	-3.0	1.5	0.8	-1.6	3.0	-2.6
Angina (self-reported)	4.1	5.4	11.6	-2.0	3.3	-2.4	-3.0	1.5	2.9	-1.7	-3.4	-1.7	-2.6	-0.4
Medication: Blood pressure	3.9	7.5	16.4	-2.8	3.9	-2.6	-3.1	2.8	2.4	-1.3	-4.0	-2.4	-3.6	-0.6
Supplements: Glucosamine	3.8	4.9	8.3	-2.7	2.9	-2.6	-2.8	2.4	2.5	-2.2	-2.1	0.2	-2.4	1.0
Medication: Paracetamol	3.8	6.3	13.0	2.6	-3.6	2.4	3.1	-1.9	-2.5	2.1	3.6	1.8	3.1	0.6
Illnesses of father: None of the above (group 1)	3.8	4.7	10.7	0.8	-2.8	2.8	2.4	-2.6	-2.8	1.1	2.0	-0.4	3.3	-1.8
Blood Platelet Count	3.7	43.1	82.6	-6.0	9.1	-8.1	-8.7	5.8	7.9	-6.4	-6.9	-1.0	-8.4	1.5
Pulse wave reflection index	3.7	4.6	11.7	0.5	-1.6	2.9	1.8	-3.4	-3.4	0.8	0.3	-2.1	2.2	-2.7
Ever had prostate specific antigen (PSA) test	3.7	4.3	8.4	-2.4	2.7	-1.8	-2.7	2.1	1.8	-1.5	-2.9	-1.5	-2.7	-0.4
Ulcerative Colitis (UC)	3.4	6.3	12.0	2.4	-3.5	3.0	2.9	-2.8	-2.7	0.9	3.3	1.2	3.4	-0.6
High blood pressure	3.4	9.4	27.6	-3.8	4.3	-2.2	-3.2	1.1	1.7	-1.4	-5.3	-4.1	-3.5	-2.0
Birth weight	3.4	7.4	15.5	2.2	-3.7	3.3	2.4	-3.6	-3.2	0.2	3.5	1.4	3.9	-1.0
Average weekly spirits intake	3.3	4.1	8.8	2.2	-2.8	2.1	2.5	-1.5	-2.0	2.2	2.3	0.5	3.0	-0.0
Cardiovascular Disease	3.2	10.5	27.7	-3.0	4.6	-3.3	-3.0	2.8	2.9	-0.4	-5.3	-3.5	-4.4	-0.5
Medication: Cholesterol lowering	3.2	4.9	12.9	-2.1	3.0	-2.1	-2.0	2.1	2.4	-0.5	-3.6	-2.5	-2.6	-0.7
Medication: Ibuprofen	3.2	3.8	7.7	1.1	-2.3	2.4	2.6	-2.6	-2.8	1.3	1.6	-0.3	2.4	-1.4
Hypertension (Self-reported)	3.2	8.8	26.6	-3.5	4.2	-2.1	-3.0	1.2	1.6	-1.1	-5.2	-3.9	-3.5	-1.7
Supplements: Fish oil (including cod liver oil)	3.2	4.1	7.2	-1.5	2.3	-2.6	-2.7	1.8	2.6	-1.8	-1.2	1.6	-2.4	2.3
Medication: Atenolol	3.0	3.8	9.6	-1.4	2.6	-2.1	-3.1	0.6	2.4	-2.5	-2.4	-0.5	-2.1	-0.2
Vascular/heart problems diagnosed by doctor	3.0	8.3	24.0	3.2	-4.1	2.1	3.2	-0.8	-1.9	1.5	4.9	3.7	3.3	1.8
Allergy	2.9	6.7	14.4	-1.8	3.4	-3.0	-3.1	3.5	3.1	-2.2	-2.1	0.5	-3.8	1.5
Illness, injury, bereavement, stress in last 2 years	2.8	3.4	8.9	-0.9	1.7	-2.8	-1.1	3.0	2.3	-0.4	-0.3	1.8	-1.8	2.8
Medication: Bendroflumethiazide	2.8	4.2	9.9	-2.0	2.9	-1.9	-2.5	1.4	1.5	-1.4	-3.1	-1.9	-2.8	-0.8
Medication for cholesterol, blood pressure or diabetes	2.6	4.3	13.8	2.1	-2.8	1.6	1.8	-1.0	-1.5	0.3	3.7	2.9	2.5	1.2
Forced expiratory volume in 1-second (FEV1)	2.5	8.4	21.3	3.3	-3.9	2.7	4.6	-1.4	-2.7	3.9	3.4	0.8	3.1	0.5
Medication: Blood pressure	2.5	4.4	12.1	-2.6	3.0	-1.5	-2.5	0.3	1.4	-1.5	-3.5	-2.3	-2.2	-1.1
Medication for cholesterol	2.5	3.7	9.4	2.1	-2.6	1.2	2.7	-0.8	-1.2	1.8	3.1	1.9	2.2	1.1
Illnesses of mother	2.4	2.9	7.3	1.3	-2.4	1.8	2.7	-1.2	-1.8	2.0	1.8	-0.0	2.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.8	19.0	3.2	-3.7	2.7	4.4	-1.5	-2.8	3.8	3.0	0.4	3.0	0.3
Glaucoma (self-reported)	2.4	2.9	5.8	2.2	-2.1	1.7	2.4	-0.2	-1.8	2.3	1.7	0.6	2.0	0.6
Number of full sisters	2.4	3.0	6.2	0.6	-1.9	2.4	2.2	-1.6	-2.5	1.5	0.9	-1.3	2.1	-1.8
Irritable Bowel Disease (IBD)	2.3	5.5	10.7	1.4	-3.1	3.3	2.6	-2.8	-2.9	0.7	2.6	0.2	3.2	-1.6
Diverticular disease/diverticulitis (self-reported)	2.3	2.8	5.6	0.9	-1.9	2.0	2.4	-2.2	-2.2	1.9	1.0	-0.9	1.7	-1.3
Chronic bronchitis/emphysema (father)	2.3	2.7	6.0	-1.6	2.3	-1.8	-2.1	1.3	1.3	-1.9	-1.8	-0.6	-2.4	-0.2
Impedance of leg (left)	2.3	11.1	25.0	0.8	2.2	-4.8	-2.2	4.9	5.0	0.2	-0.3	2.6	-4.5	4.8
Medication: Ibuprofen (e.g. Nurofen)	2.3	3.0	5.3	1.2	-2.1	2.2	2.3	-2.2	-2.3	0.9	1.7	0.1	2.2	-1.1
High blood pressure (siblings)	2.3	3.3	6.9	-2.5	2.5	-1.0	-2.2	-0.0	0.7	-1.8	-2.6	-1.6	-2.5	-1.0
Eye problems/disorders: Cataract	2.3	2.7	5.9	2.1	-2.1	1.2	2.1	-1.9	-1.4	2.4	1.6	0.9	1.3	0.8
Mineral and other dietary supplements	2.3	3.1	6.6	1.6	-2.1	2.0	2.6	-1.6	-2.0	2.0	1.2	-1.2	2.0	-1.6
Hand grip strength (right)	2.2	5.9	12.1	-2.4	3.4	-3.5	-2.2	2.6	3.1	-1.0	-2.7	-0.5	-3.3	1.3
Serious illness, injury or assault to yourself	2.2	2.7	5.6	1.4	-1.9	2.4	2.0	-1.7	-2.0	1.3	1.1	-0.8	2.0	-1.5
Comparative height size at age 10	2.2	11.8	30.2	-3.4	4.8	-3.9	-3.8	3.9	3.2	-2.5	-4.0	-0.6	-5.5	1.0
Illnesses of father: High blood pressure	2.2	2.7	6.4	-1.7	2.5	-1.9	-2.1	0.5	1.7	-2.0	-2.0	-0.4	-2.0	0.1
Pain experienced in last month	2.2	3.7	7.8	-2.2	2.4	-2.6	-2.8	1.0	2.3	-1.9	-2.0	-0.3	-2.2	0.2
Primary Biliary Cirrhosis	2.1	2.9	9.4	-1.0	-1.0	2.3	0.0	-3.1	-2.2	-1.4	0.6	-0.8	2.3	-2.5
Type 2 Diabetes (T2D) (2012)	2.1	2.4	7.5	1.3	0.7	-2.0	0.2	2.7	2.2	1.6	-0.4	0.8	-1.2	2.4
Pain all over the body in last month	2.1	2.2	4.7	0.4	-1.5	2.2	2.0	-1.6	-2.1	0.9	0.8	-1.1	1.8	-1.6
Eye problems/disorders: None of the above	2.1	2.5	9.7	-1.6	1.9	-1.1	-2.3	1.4	1.4	-3.1	-1.0	0.0	-1.4	-0.5
Medication for pain relief, constipation, heartburn	2.1	3.7	8.4	-2.4	2.3	-1.6	-2.7	1.9	1.7	-2.9	-1.8	-0.4	-2.0	-0.6
LDL Cholesterol	2.0	3.1	9.8	2.6	-1.9	-0.0	1.3	0.4	-0.0	0.8	2.6	3.1	1.1	2.5
Impedance of leg (right)	2.0	9.6	21.2	0.6	2.2	-4.6	-1.9	4.5	4.6	0.3	-0.4	2.3	-4.4	4.5
Exposure to tobacco smoke at home	2.0	2.3	5.3	2.0	-2.1	1.2	2.2	-0.9	-1.1	2.3	1.8	0.4	1.6	0.3
Medication: Amlodipine	2.0	2.8	5.3	-1.2	2.3	-2.0	-2.2	1.9	2.3	-1.2	-1.7	-0.2	-2.0	0.9
Age at first live birth	2.0	3.6	10.2	-0.8	2.4	-2.7	-2.3	1.8	2.2	-0.9	-1.6	0.5	-3.2	1.6
Eye problems/disorders: Glaucoma	2.0	2.4	5.5	1.5	-2.2	2.0	1.6	-1.1	-1.9	1.2	1.7	0.6	2.3	-0.2
Fasting Glucose	1.9	2.2	7.6	2.8	-1.2	-0.7	1.2	0.3	1.0	0.8	2.1	2.2	0.4	2.1
Hand grip strength (left)	1.9	5.1	10.5	-2.1	3.2	-3.2	-1.9	2.4	2.6	-0.6	-2.8	-1.0	-3.2	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.9	2.9	5.6	2.1	-2.4	2.3	1.8	-1.9	-1.8	1.0	1.9	0.4	2.2	-0.7
Illnesses of siblings	1.9	2.6	7.7	1.6	-2.3	1.2	1.7	-0.7	-1.1	0.6	2.8	1.8	2.4	0.6
Length of working week for main job	1.9	2.1	5.9	2.3	-1.5	0.3	2.4	-0.2	-0.6	2.1	1.9	1.2	0.8	1.2
Body mass index (BMI)	1.8	7.6	23.1	1.6	-3.2	3.8	2.9	-3.2	-3.3	1.2	2.1	-0.4	4.8	-2.2
Medication: Simvastatin	1.8	2.6	4.8	-1.7	2.1	-2.0	-1.9	1.3	2.2	-1.2	-2.2	-0.9	-1.9	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	5.9	0.6	-1.8	2.0	1.9	-1.1	-2.0	1.3	1.3	-0.2	2.4	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	4.2	0.1	-1.0	2.0	1.8	-1.3	-2.0	1.3	0.2	-1.7	1.0	-1.8
High cholesterol (Self-reported)	1.8	3.2	6.6	-1.5	2.4	-2.0	-2.0	2.1	2.2	-0.5	-2.6	-1.3	-2.3	0.2
Medication: Paracetamol	1.8	2.9	5.7	1.8	-2.4	1.6	2.3	-1.0	-1.7	1.8	2.3	0.9	2.0	0.5
Fractured/broken bones in last 5 years	1.8	2.3	8.0	-1.9	1.7	-0.4	-0.3	0.6	0.3	0.7	-2.8	-2.8	-1.7	-1.3
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	4.5	1.9	-2.1	1.5	2.0	-1.5	-1.3	1.3	1.7	0.9	2.1	0.2
Impedance of whole body	1.8	9.0	20.7	0.0	2.5	-4.2	-2.5	4.5	4.5	-0.8	-0.8	2.0	-4.2	3.7
Number of incorrect matches in round	1.7	2.8	6.7	-1.6	2.0	-1.9	-2.6	1.4	2.0	-1.7	-1.4	-0.0	-2.3	0.5
Age started oral contraceptive pill	1.7	2.2	3.6	-1.4	1.6	-1.9	-1.7	1.5	1.9	-1.6	-1.0	1.0	-1.8	1.2
BMI	1.6	9.2	26.5	2.1	-3.6	4.1	3.1	-3.8	-3.8	1.1	2.6	-0.0	5.2	-2.0
Hair/balding pattern: Pattern 2	1.6	2.0	4.1	-1.3	1.8	-2.0	-1.5	1.8	1.6	-0.4	-1.6	-0.2	-2.0	1.0
Blood clot in the leg (DVT)	1.6	2.0	4.0	1.7	-2.0	1.6	1.8	-1.5	-1.3	1.1	1.5	0.7	2.0	-0.0
Illnesses of father: Heart disease	1.6	2.3	5.4	-0.1	1.6	-1.9	-1.5	2.3	2.3	-0.1	-1.2	0.3	-2.1	1.5
Medication: Gliclazide	1.6	1.8	5.3	2.0	-0.5	-0.9	1.0	1.4	1.1	2.0	1.0	1.5	0.1	2.3
Height	1.5	29.2	60.2	-5.6	7.8	-6.1	-5.8	5.4	5.3	-3.5	-7.2	-2.6	-7.6	0.8
Arm fat percentage (right)	1.5	5.7	18.1	1.8	-3.0	3.3	2.8	-2.2	-2.6	1.2	2.2	-0.1	4.3	-1.6
Standing height	1.5	14.6	37.0	-3.5	5.4	-4.7	-3.9	4.1	3.8	-2.2	-4.6	-1.1	-6.1	1.5
Hair/balding pattern: Pattern 4	1.5	3.5	10.4	0.8	-2.1	3.1	1.2	-2.2	-2.1	-0.2	1.6	-0.2	3.2	-2.0
Body Mass Index (BMI) (2010)	1.4	1.9	4.5	0.7	-1.7	2.1	1.5	-1.4	-2.1	0.9	1.0	-0.2	2.0	-0.9
Diabetes (father)	1.4	1.8	5.5	1.8	-1.4	0.1	1.6	1.1	0.2	2.3	1.4	1.0	0.7	1.7
Financial difficulties in last 2 years	1.4	1.9	6.4	-0.6	-0.6	1.7	-0.2	-2.5	-1.4	-0.7	-0.3	-1.5	1.3	-2.4
Depression (self-reported)	1.4	1.7	8.6	1.0	-0.3	-0.4	-0.9	-0.6	0.7	-1.8	1.6	2.9	0.4	1.5
Number of operations (self-reported)	1.4	2.1	5.2	0.3	-1.3	2.3	1.3	-2.1	-2.2	0.8	0.6	-1.0	1.6	-1.8
Chronotype (morning person)	1.3	3.0	7.4	-2.7	2.0	-1.0	-2.5	0.8	1.0	-2.4	-2.0	-1.6	-1.3	-1.4
Diabetes (mother)	1.3	1.6	8.4	2.9	-0.6	-0.6	0.6	0.7	1.3	1.2	1.3	1.2	0.2	1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	7.5	-1.6	2.4	-1.9	-1.8	1.9	1.3	-1.1	-1.8	-0.2	-2.7	0.8
Arm fat percentage (left)	1.3	5.2	17.2	1.6	-2.8	3.1	2.5	-2.1	-2.4	0.9	2.2	-0.0	4.2	-1.6
Commuting to job workplace: Walk	1.3	1.4	6.6	-1.4	1.2	-0.8	-2.0	-0.6	1.0	-2.6	-0.8	0.4	-0.6	-0.3
Ever taken oral contraceptive pill	1.3	1.4	5.7	0.8	-0.6	-1.1	0.0	0.7	1.2	0.1	1.4	2.4	-0.0	2.3
Schizophrenia (2018)	1.2	2.5	8.4	-0.0	-1.1	2.3	0.8	-2.9	-2.0	-0.7	0.8	-0.5	2.2	-1.9
Alcohol usually taken with meals	1.2	1.9	4.5	0.5	-1.4	2.1	1.2	-2.1	-1.9	-0.0	0.7	-0.1	2.0	-1.3
Loud music exposure frequency	1.2	1.3	4.7	2.2	-1.4	0.3	0.8	-0.2	-0.6	1.1	1.7	1.5	0.4	1.3
Heart disease (mother)	1.2	1.4	5.1	-1.6	1.5	-0.5	-1.2	0.5	0.7	-0.2	-2.3	-1.6	-1.3	-0.7
Alcohol intake frequency.	1.2	2.9	6.1	2.0	-2.5	2.1	1.8	-0.5	-1.6	0.8	2.5	0.9	2.4	-0.3
Had major operations	1.2	1.4	3.8	0.5	-1.4	1.9	0.7	-2.0	-1.4	0.4	0.8	-0.1	1.6	-1.0
Age at last live birth	1.2	1.8	5.2	-1.0	1.8	-1.5	-1.6	1.4	1.2	-0.9	-1.2	0.3	-2.3	0.9
Diastolic blood pressure, automated reading	1.2	3.7	7.6	-2.6	2.6	-1.6	-2.4	1.6	1.3	-1.5	-2.7	-1.3	-2.4	-0.6
Rheumatoid Arthritis	1.1	1.6	3.8	1.4	-1.4	1.2	1.0	-1.4	-1.4	-0.2	2.0	1.5	1.6	0.3
Blood White Count	1.1	7.9	19.3	-0.5	2.7	-3.9	-3.2	3.1	4.4	-2.8	-0.8	2.5	-3.1	2.8
Medication: Metformin	1.1	1.5	3.9	1.0	0.8	-1.4	0.1	2.0	1.6	2.0	-1.0	-0.8	-1.1	1.2
Mouth/teeth dental problems	1.1	1.7	4.2	0.5	0.8	-1.7	-1.3	2.1	1.9	-0.8	-0.1	1.4	-1.2	1.8
Medication: Ramipril	1.1	1.5	6.6	-0.9	1.3	-0.5	-0.1	0.2	0.4	0.9	-2.2	-2.6	-0.9	-1.3
Happiness	1.1	1.3	3.3	0.5	0.8	-1.8	0.0	1.8	1.3	1.3	-0.8	-0.2	-1.8	1.3
Arm fat mass (right)	1.1	4.7	14.4	1.3	-2.5	3.1	2.5	-2.3	-2.7	1.0	1.6	-0.4	3.8	-1.7
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	4.6	-1.4	1.8	-0.7	-2.2	0.5	0.9	-2.1	-1.5	-0.7	-1.5	-0.6
Leg fat mass (right)	1.1	4.3	14.2	1.4	-2.5	2.8	2.4	-2.1	-2.2	1.0	1.7	-0.2	3.8	-1.5
Leg pain on walking	1.1	1.4	3.0	0.9	-1.7	1.2	1.2	-1.5	-1.0	0.4	1.6	0.9	1.7	-0.2
Arm fat mass (left)	1.1	4.5	14.2	1.1	-2.4	3.0	2.3	-2.3	-2.6	0.6	1.6	-0.4	3.8	-1.8
Cholesterol lowering medication	1.1	1.6	3.6	-0.5	1.6	-1.6	-1.7	1.0	1.9	-0.9	-1.3	0.0	-1.6	0.8
Supplements: Calcium	1.1	1.3	3.8	-1.2	1.4	-1.0	-1.4	1.6	0.6	-0.8	-1.1	0.0	-1.9	0.4
Leg fat mass (left)	1.1	4.2	13.9	1.4	-2.5	2.7	2.4	-2.0	-2.2	1.0	1.8	-0.2	3.7	-1.4
Type 2 Diabetes (T2D) (2018)	1.0	1.8	9.5	1.6	0.1	-0.7	1.0	1.7	1.4	3.1	-0.9	-1.1	-0.1	1.2
Ever had hysterectomy (womb removed)	1.0	1.2	3.2	0.7	-1.4	1.4	0.9	-1.5	-1.1	0.3	1.1	0.9	1.8	0.1
Qualifications: None of the above	1.0	2.1	4.8	0.7	-1.8	1.9	1.9	-1.6	-1.5	1.3	1.0	-0.5	2.2	-1.1
Alcohol intake versus 10 years previously	1.0	1.5	3.0	1.0	-1.4	1.7	1.6	-1.2	-1.6	1.3	1.0	-0.3	1.4	-0.6
Prospective memory result	1.0	1.2	4.2	-0.1	-0.7	1.4	0.2	-1.5	-0.9	-0.1	-0.4	-1.5	1.3	-2.0
Impedance of arm (left)	1.0	4.7	12.7	-0.2	2.0	-2.9	-2.0	3.6	3.1	-1.1	-0.7	1.3	-3.0	2.3
Migraine (self-reported)	1.0	1.2	2.7	1.7	-1.6	0.9	1.6	-0.7	-0.7	1.2	1.3	0.4	1.1	0.1
Supplements: Vitamin C	1.0	1.2	3.2	-0.4	1.5	-1.3	-1.6	0.7	1.3	-1.0	-0.7	0.5	-1.8	0.9
Mood swings	1.0	1.8	4.0	1.3	-1.8	1.8	1.5	-1.6	-1.1	0.8	1.7	0.3	2.0	-0.5
Diabetes diagnosed by doctor	1.0	1.6	6.7	1.1	0.5	-0.9	0.7	1.8	1.5	2.6	-1.3	-1.3	-0.4	0.8
Breast cancer (self-reported)	1.0	1.2	2.5	-1.6	1.3	-1.1	-1.2	1.5	1.1	-0.3	-1.2	-0.6	-1.6	0.2
Alcohol drinker status: Never	1.0	1.2	3.5	-0.7	-0.6	1.4	0.1	-1.9	-1.4	-1.2	0.2	-0.6	1.2	-1.8
Irritability	1.0	1.7	4.5	1.0	-1.2	1.5	2.1	-1.2	-1.3	1.9	0.6	-0.9	1.5	-0.6
Basal cell carcinoma (self-reported)	1.0	1.2	3.3	-0.7	-0.8	1.6	0.3	-1.1	-1.4	0.4	-0.3	-1.5	1.1	-1.8
Prostate Cancer	0.9	1.3	4.7	1.7	-0.1	-1.2	0.1	0.8	1.1	0.7	0.9	1.7	-0.6	2.2
Crohns Disease (2012)	0.9	1.5	3.3	0.8	-1.8	1.5	1.3	-1.4	-1.5	0.8	1.5	0.0	1.5	-0.7
Lung FVC	0.9	4.8	9.7	1.6	-3.0	2.3	3.1	-2.2	-2.5	2.4	2.6	0.4	2.6	-0.3
Number of treatments/medications taken	0.9	1.6	4.5	-1.4	1.8	-0.9	-1.8	0.0	0.8	-1.3	-2.1	-1.2	-1.1	-0.7
Relative age of first facial hair	0.9	1.9	3.7	-1.3	1.4	-1.9	-1.1	1.3	1.8	-0.9	-0.3	1.5	-1.7	1.9
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	2.4	0.8	-1.1	1.3	1.1	-1.4	-1.6	1.0	0.5	-0.3	1.3	-0.2
Multivitamins +/- minerals	0.9	1.1	4.8	0.3	0.2	-0.6	-1.4	-0.2	0.8	-1.8	0.8	2.2	-0.1	1.3
Waist circumference	0.9	3.2	11.2	0.6	-1.8	2.6	1.6	-2.2	-2.0	-0.1	1.1	-0.4	3.4	-1.9
Impedance of arm (right)	0.9	4.0	9.8	-0.8	2.0	-2.6	-2.1	3.1	2.8	-1.2	-1.0	0.7	-3.0	1.6
Asthma	0.9	1.7	4.5	-2.0	1.9	-0.9	-1.0	0.2	-0.1	-0.4	-2.1	-1.8	-1.6	-0.8
Leg fat percentage (right)	0.9	3.3	10.2	2.0	-2.5	1.9	2.3	-1.1	-1.1	1.4	2.2	0.7	3.2	-0.1
Leg fat percentage (left)	0.9	3.2	10.6	2.0	-2.6	1.8	2.1	-1.0	-1.1	1.3	2.3	0.9	3.3	-0.1
Risk taking	0.9	1.4	2.8	1.5	-1.4	1.0	1.7	-1.1	-1.1	1.6	1.2	0.3	1.5	0.2
Intelligence (Savage-Jansen 2018)	0.8	2.4	7.2	-0.3	-1.4	1.9	1.2	-2.7	-1.9	0.9	0.3	-1.5	1.9	-2.0
Ovarian Cancer	0.8	1.1	2.7	-0.7	1.0	-1.6	-1.2	1.4	1.6	-0.5	-0.5	0.4	-1.0	1.0
Age at First Birth	0.8	1.1	3.2	-1.8	1.1	0.1	-0.9	-0.3	-0.2	-0.8	-1.6	-1.5	-0.4	-1.6
Hypothyroidism (self reported)	0.8	1.9	4.3	-1.9	1.3	-1.4	-2.1	1.0	1.8	-1.8	-1.1	0.3	-1.5	0.3
Sensitivity / hurt feelings	0.8	1.5	2.7	1.0	-1.6	1.5	1.6	-1.4	-1.3	1.6	1.0	-0.2	1.3	-0.3
Medication for hormone replacement therapy	0.8	0.8	2.1	-1.1	1.0	-0.4	-1.4	-0.1	0.2	-1.0	-1.5	-0.9	-0.9	-0.8
Vitamin and mineral supplements	0.8	1.1	5.3	1.0	-0.9	0.4	2.0	0.6	-0.6	2.3	0.3	-0.7	0.7	0.1
Nervous feelings	0.8	1.5	6.3	-1.2	0.2	1.5	-0.6	-0.6	-1.2	-0.9	-0.8	-2.0	0.8	-2.5
Bipolar Disorder or Schizophrenia	0.7	1.7	5.3	0.9	-1.0	1.7	0.5	-2.3	-1.2	-1.0	1.4	0.9	1.9	-0.7
Alzheimer’s Disease (in father)	0.7	0.8	2.2	0.8	0.5	-1.0	-0.9	0.9	0.5	-0.4	0.2	1.3	-1.2	1.5
HbA1C	0.7	0.7	2.0	-0.6	1.0	-0.5	-1.1	1.4	0.7	-0.8	-0.8	-0.3	-1.4	0.2
Neuroticism (2016)	0.7	1.0	3.7	-0.9	0.1	0.6	-1.0	-1.0	-0.3	-1.4	-0.9	-1.4	0.6	-1.9
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.9	1.4	-1.0	0.8	1.4	-0.3	-1.1	2.0	0.3	-0.2	0.4	0.2
Supplements: Zinc	0.7	0.7	1.7	-1.2	0.9	-0.2	-1.2	0.2	0.2	-1.3	-1.2	-0.8	-0.5	-1.0
Severe depression (siblings)	0.7	0.8	4.8	-1.0	0.9	-0.0	-1.4	-0.1	0.1	-2.2	-0.6	-0.0	-0.2	-0.8
Medication: Levothyroxine sodium	0.7	1.2	3.0	-0.7	1.0	-1.1	-1.7	0.6	1.2	-1.7	-0.3	1.2	-1.0	1.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.0	-1.0	0.8	-1.3	-1.7	1.4	1.5	-1.4	-0.2	1.2	-1.2	1.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.1	-1.2	0.8	-0.1	-0.8	-0.9	0.1	-0.8	-1.2	-1.4	-0.2	-1.4
Medication: Omeprazole	0.7	0.9	3.7	1.9	-0.7	0.2	0.7	-1.1	-0.0	0.6	1.2	1.2	0.8	1.0
Asthma (self-reported)	0.7	1.4	3.9	-1.7	1.7	-0.9	-0.8	0.4	-0.0	-0.1	-2.0	-1.7	-1.6	-0.6
Bipolar Disorder (2018)	0.6	0.9	4.2	1.6	-0.2	-0.1	-0.2	0.2	0.5	-0.7	1.3	2.0	0.4	1.3
HDL Cholesterol	0.6	1.0	4.4	-0.5	0.5	0.5	-1.5	-1.6	-0.5	-2.1	-0.2	-0.3	0.0	-1.3
Schizophrenia (2014)	0.6	1.2	4.7	0.2	-0.6	1.6	0.1	-2.2	-1.2	-1.0	0.6	-0.0	1.7	-1.3
Heel T-Score	0.6	5.1	10.7	3.1	-2.6	-0.1	2.6	0.8	0.3	2.2	3.3	3.1	1.8	3.0
Respiratory disease	0.6	1.3	3.9	-2.0	1.2	-0.2	-0.7	-0.2	-0.3	-0.7	-1.7	-1.8	-0.6	-1.6
Leg fat-free mass (left)	0.6	3.0	8.1	-0.9	-0.4	2.3	1.1	-2.1	-2.5	-0.2	-0.8	-2.1	2.0	-2.9
Townsend deprivation index at recruitment	0.6	0.9	4.0	-0.5	-0.0	1.2	-0.3	-1.1	-0.5	-1.1	-0.5	-1.2	0.9	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.3	0.8	-0.6	1.4	0.1	-1.5	-0.9	-0.5	0.4	-0.3	1.3	-1.1
Leg predicted mass (left)	0.6	3.2	8.5	-0.9	-0.5	2.4	1.2	-2.2	-2.6	-0.2	-0.7	-2.2	2.1	-2.9
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	3.2	1.8	-1.6	0.9	1.8	-0.2	-0.7	1.8	0.9	-0.2	1.2	-0.1
Diabetes (self-reported)	0.6	1.0	4.3	0.9	0.3	-0.4	0.5	1.4	1.0	2.1	-1.1	-1.4	-0.2	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	3.0	1.7	-1.4	1.2	1.0	-0.4	-0.7	0.8	1.1	0.3	1.1	-0.1
Number of live births	0.6	0.9	2.3	0.2	-1.4	1.5	0.6	-0.5	-1.4	-0.1	1.2	0.5	1.4	-0.5
Pulse rate	0.6	1.0	3.2	1.1	-1.1	-0.1	1.3	0.8	0.1	1.8	1.1	1.1	0.2	1.3
Mouth/teeth dental problems: Dentures	0.6	0.9	1.7	-0.2	-0.9	1.3	1.0	-1.2	-1.3	1.2	-0.1	-1.0	1.2	-1.0
Medication: Lansoprazole	0.6	0.7	1.8	-1.3	0.7	-0.0	-1.1	0.8	0.3	-0.9	-0.9	-1.0	-0.2	-0.9
Medication: Seretide 50 evohaler	0.6	0.7	1.6	-1.2	1.1	-0.8	-0.8	0.3	0.3	-0.6	-1.2	-0.9	-1.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.8	0.3	-1.2	1.3	0.6	-1.2	-1.0	0.1	0.8	-0.0	1.1	-0.8
Average weekly champagne plus white wine intake	0.6	0.9	2.0	-0.7	1.1	-1.2	-1.3	0.5	1.1	-1.4	-0.4	0.6	-1.1	0.6
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.4	-0.1	1.6	-1.1	-0.5	-0.1	1.1	0.3	-1.5	-0.6	-1.4	0.5
Schizophrenia vs Biploar Disorder	0.5	0.7	1.7	-0.2	0.9	-1.0	-0.9	1.0	1.1	-1.3	-0.1	0.7	-0.9	0.6
Lupus	0.5	0.7	3.6	0.9	-1.0	0.5	1.3	-0.0	-0.9	1.9	0.6	-0.4	-0.1	0.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.7	0.5	-0.4	1.1	-0.3	-1.6	-0.4	-0.7	0.1	-0.4	1.1	-1.1
Relative age voice broke	0.5	0.7	2.6	0.1	-0.5	0.6	1.3	-0.9	-1.0	1.6	0.0	-1.1	0.2	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.3	1.7	-1.3	0.5	1.8	0.2	-0.6	1.8	0.9	0.2	1.0	0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.0	-0.7	0.7	-0.8	-1.4	0.0	0.2	-1.2	-0.4	0.6	-0.9	0.4
Had other major operations	0.5	0.6	2.2	1.5	-0.7	-0.1	0.8	0.4	-0.1	0.9	1.0	0.8	-0.0	0.9
Heart attack	0.5	0.7	1.9	-0.0	1.4	-1.0	-0.3	-0.1	1.1	0.3	-1.4	-0.5	-1.2	0.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	2.2	-0.2	-0.3	1.1	0.1	-1.5	-1.1	-0.9	0.3	-0.2	1.0	-1.0
Worrier / anxious feelings	0.5	1.0	2.1	-1.1	1.4	-1.1	-1.1	1.1	1.0	-0.8	-1.1	-0.2	-1.4	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.7	1.5	-0.8	0.4	0.2	-0.2	-0.0	-0.3	1.3	1.6	0.5	0.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.8	-0.4	0.7	-1.1	-0.2	1.7	1.1	0.3	-0.5	-0.2	-0.6	0.6
Exposure to tobacco smoke outside home	0.5	0.6	1.8	0.1	-0.8	1.3	0.7	-1.0	-1.3	0.2	0.3	-0.5	0.8	-1.0
Number of children fathered	0.5	0.6	2.0	-1.4	0.2	0.4	-0.4	-0.6	-0.6	-0.9	-0.5	-0.9	0.4	-1.4
Shortness of breath walking on level ground	0.5	0.6	1.3	1.1	-0.8	-0.3	0.7	0.4	0.5	1.1	0.8	0.8	0.5	1.0
Whole body fat mass	0.5	1.9	7.5	0.9	-1.6	1.9	1.6	-1.2	-1.4	0.5	1.1	-0.1	2.7	-1.0
Illnesses of siblings: Diabetes	0.5	0.7	2.0	1.3	-1.0	0.8	1.1	-0.3	-0.6	1.4	0.5	0.1	0.7	0.3
Leg fat-free mass (right)	0.5	2.4	6.8	-0.8	-0.3	2.0	0.9	-1.9	-2.3	-0.3	-0.8	-1.9	1.8	-2.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	-1.0	1.0	-0.4	-1.2	0.3	0.2	-0.8	-0.8	-0.6	-1.1	-0.4
Loneliness, isolation	0.5	0.7	1.6	0.9	-0.7	1.2	1.2	-0.5	-0.8	0.9	0.3	-0.8	0.8	-1.0
Back pain experienced in last month	0.5	0.7	2.3	1.2	-1.1	0.5	1.0	-0.1	-0.2	0.4	1.5	1.1	0.8	0.7
Leg predicted mass (right)	0.5	2.5	7.1	-0.9	-0.2	2.1	0.9	-1.9	-2.3	-0.4	-0.8	-2.0	1.8	-2.7
Guilty feelings	0.5	0.7	4.1	-0.7	0.4	0.6	-1.1	-0.5	0.0	-2.0	-0.3	-0.3	0.6	-1.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.7	-0.2	0.4	-1.0	-0.7	1.3	1.6	0.2	-0.3	0.2	-0.6	0.8
Commuting to job workplace: Public transport	0.5	0.6	2.6	-1.3	0.6	0.5	-0.9	-0.3	-0.4	-1.6	-0.4	-0.5	-0.1	-1.0
Medication: Lisinopril	0.5	0.7	1.7	-0.9	1.3	-0.4	-1.3	0.4	0.5	-1.0	-1.2	-0.5	-0.9	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.3	1.0	0.3	-0.9	-0.2	-0.2	1.0	0.3	0.3	1.2	-0.5	1.5
Depressed Affect (Nagel 2018)	0.4	0.9	2.7	1.6	-1.1	1.1	0.8	-0.4	-0.5	0.3	1.6	1.0	1.1	0.4
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-0.2	0.6	-0.7	-1.3	0.5	0.9	-1.0	-0.2	0.8	-0.5	0.6
Alzheimer’s Disease (including proxy)	0.4	0.6	2.3	0.2	0.2	-0.3	-1.2	0.5	0.4	-1.3	0.4	1.5	-0.3	0.9
Crohns Disease (2017)	0.4	0.8	2.0	0.1	-1.2	1.4	1.1	-1.0	-1.2	0.3	1.0	-0.2	1.1	-0.9
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.6	0.5	-1.2	1.0	0.7	-1.9	-0.9	-0.2	1.1	0.4	1.7	-0.7
Breast Cancer	0.4	0.9	3.1	-0.1	0.9	-1.3	-0.6	1.3	0.8	0.4	-1.1	-0.1	-1.8	0.8
Mean Putamen Volume	0.4	0.5	1.3	-0.4	-0.4	1.1	0.1	-0.8	-0.9	-0.4	-0.0	-0.5	1.0	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.8	-0.3	0.1	0.2	0.6	-0.6	-0.4	1.2	-0.7	-1.4	0.1	-0.8
Average weekly fortified wine intake	0.4	0.5	1.2	1.1	-0.7	0.0	1.0	0.1	-0.4	1.1	0.6	0.7	0.3	1.0
Fed-up feelings	0.4	0.7	1.8	1.2	-1.0	1.0	0.6	-1.1	-0.4	0.0	1.3	0.4	1.3	-0.2
Age when periods started (menarche)	0.4	0.9	3.8	1.2	-0.8	0.1	-0.0	-0.8	0.2	-0.5	1.4	2.0	0.7	1.1
Qualifications: CSEs or equivalent	0.4	0.6	1.3	-0.7	0.9	-0.6	-0.2	0.9	0.9	0.3	-1.1	-1.1	-1.1	-0.4
Noisy workplace	0.4	0.5	2.5	0.4	-0.2	0.0	-0.6	0.4	0.1	-1.0	0.9	1.6	0.2	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.0	-0.1	0.0	0.4	0.8	-0.6	-0.6	0.8	-0.6	-1.4	-0.3	-1.0
Lung cancer (father)	0.4	0.5	1.5	0.2	-1.0	1.0	0.7	-0.7	-0.8	0.5	0.5	-0.1	1.2	-0.5
Body fat percentage	0.4	1.7	7.1	1.3	-1.8	1.5	1.6	-0.6	-0.8	0.7	1.5	0.4	2.7	-0.3
Neck or shoulder pain in last month	0.4	0.6	2.8	-0.5	0.5	0.4	0.1	0.7	-0.0	0.6	-1.2	-1.7	-0.1	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.6	-0.4	-0.5	1.3	0.4	-0.8	-1.0	-0.2	0.1	-0.3	1.1	-0.8
Overall health rating	0.4	0.9	2.5	0.6	-0.7	1.5	0.6	-0.9	-1.0	0.3	-0.1	-1.4	1.0	-1.6
Family relationship satisfaction	0.4	0.5	1.5	0.8	-0.0	-1.2	0.0	0.5	1.2	0.7	0.0	0.4	-0.4	1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.9	0.9	-0.6	0.1	1.1	-0.3	-0.3	1.4	0.4	0.0	0.5	0.5
Long-standing illness, disability or infirmity	0.4	0.6	2.9	-0.4	0.4	0.2	-0.0	-0.7	-0.2	0.6	-1.4	-1.7	-0.2	-1.2
Ever had bowel cancer screening	0.4	0.4	1.3	-0.5	-0.1	1.1	-0.2	-0.3	-1.0	-1.0	0.2	-0.0	0.6	-0.9
Qualifications: nursing, teaching	0.4	0.6	1.6	0.3	1.0	-0.9	-0.2	1.0	0.2	0.8	-1.0	-1.0	-1.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.1	1.1	-0.7	0.3	0.7	0.4	-0.1	0.7	0.8	0.8	0.7	0.8
Osteoporosis (self-reported)	0.4	0.5	1.7	-0.8	0.6	0.4	0.0	0.1	-0.7	0.1	-1.0	-1.3	-0.5	-1.0
Medication: Aspirin	0.4	0.5	2.4	-0.3	0.9	-0.5	-0.5	0.4	0.7	0.6	-1.5	-1.1	-0.6	-0.0
Number of self-reported non-cancer illnesses	0.4	0.6	2.7	-0.5	1.1	-0.7	-0.3	0.5	0.2	0.5	-1.6	-1.2	-1.1	-0.1
Myopia	0.4	0.6	3.4	0.9	-0.4	-0.2	1.3	0.5	0.0	1.8	-0.0	-0.2	0.0	0.6
Pack years of smoking	0.4	0.5	1.9	1.1	-0.7	0.3	1.4	-0.4	-0.5	1.1	0.6	0.0	0.8	0.1
Reaction Time	0.3	0.6	3.0	-1.0	0.0	0.7	-0.2	0.0	-0.3	0.4	-0.8	-1.7	0.2	-1.3
Triglycerides	0.3	0.5	1.0	0.8	-0.8	0.1	0.7	0.8	-0.1	0.8	0.9	1.0	0.3	0.9
Waist Hip Ratio (WHR)	0.3	1.5	3.1	1.7	-1.7	1.5	1.8	-0.6	-0.8	1.0	1.6	0.4	1.6	-0.2
Neuroticism	0.3	0.6	1.3	1.1	-0.8	1.0	0.9	-0.8	-0.8	0.5	0.9	-0.0	1.1	-0.3
Pack years adult smoking proportion	0.3	0.4	1.5	0.9	-0.6	0.5	1.2	-0.5	-0.6	1.0	0.4	-0.3	0.8	-0.2
Trunk fat percentage	0.3	1.1	5.0	1.2	-1.4	1.1	1.3	-0.1	-0.5	0.5	1.2	0.5	2.2	-0.1
Current tobacco smoking	0.3	0.4	1.1	0.9	-0.6	0.8	0.9	-0.4	-1.0	0.9	0.4	-0.5	0.3	-0.3
Past tobacco smoking	0.3	0.5	1.8	1.3	-0.6	0.3	-0.1	0.4	-0.4	-0.4	0.9	1.3	0.2	0.7
Had menopause	0.3	0.3	1.1	-0.3	0.2	-0.6	-0.0	1.0	0.1	0.9	-0.7	0.2	-0.8	0.8
Forced vital capacity (FVC)	0.3	1.0	3.4	-0.9	1.0	-1.3	0.2	1.4	0.8	0.9	-0.8	-0.6	-1.8	0.7
Weight	0.3	1.3	4.0	0.0	-0.7	1.6	1.1	-1.3	-1.5	0.1	0.0	-0.9	2.0	-1.5
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.5	-1.0	1.1	-0.6	-1.0	0.1	0.2	-0.7	-1.1	-0.8	-1.2	-0.4
Tense / ‘highly strung’	0.3	0.6	1.9	1.4	-0.6	0.8	1.1	-0.5	-0.8	1.1	0.4	-0.4	0.5	-0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.4	-0.3	0.9	-0.1	-0.5	0.4	-0.7	-0.3	-0.9	-0.6	-1.5	-0.2
Forced vital capacity (FVC), Best measure	0.3	1.2	3.9	-0.8	1.3	-1.4	-0.1	1.4	0.8	0.8	-1.2	-0.9	-2.0	0.6
Comparative body size at age 10	0.3	0.9	3.6	-1.9	0.7	0.2	-0.6	0.2	-0.1	-0.7	-1.2	-1.4	0.0	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.9	-0.4	-0.1	-0.0	-0.5	0.2	-0.5	1.0	1.3	0.3	0.7
Wheeze or whistling in the chest in last year	0.3	0.5	2.2	-0.2	-0.4	0.9	0.4	-1.0	-1.5	0.0	0.1	-0.7	0.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.6	0.4	-0.3	0.1	1.0	-0.5	-0.5	1.6	-0.1	-0.5	0.1	0.3
Health satisfaction	0.3	0.3	1.8	1.3	-0.8	0.4	0.1	-0.6	-0.2	-0.1	0.8	0.2	0.6	-0.3
Qualifications: College or University degree	0.3	1.0	2.8	0.7	0.7	-1.7	-0.7	0.4	0.8	-0.2	0.1	1.1	-1.6	1.7
Chest pain or discomfort	0.3	0.4	1.5	-0.0	0.5	0.0	0.2	0.4	-0.1	0.9	-1.1	-1.2	-0.5	-0.5
Medication: Aspirin	0.3	0.4	1.3	0.3	0.7	-0.7	-0.2	0.5	0.9	0.8	-1.2	-0.6	-0.6	0.5
Knee pain experienced in last month	0.3	0.4	1.3	-0.2	-0.4	1.2	-0.3	-0.5	-0.6	-1.1	0.3	0.3	1.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.9	-0.9	0.6	0.1	-0.7	-0.5	-0.0	-1.4	-0.5	-0.5	0.1	-0.9
Whole body water mass	0.3	1.5	4.4	-1.2	0.4	1.2	0.5	-1.3	-1.6	-0.2	-1.3	-2.0	0.7	-2.1
Hearing aid user	0.3	0.4	0.9	0.8	-0.9	0.7	0.6	-0.4	-0.7	0.1	0.9	0.6	0.6	0.1
Mother’s age at death	0.3	0.3	1.0	1.0	-0.5	0.3	0.5	-0.2	-0.2	0.2	0.9	1.0	0.0	0.7
Financial situation satisfaction	0.3	0.3	0.7	-0.7	0.7	-0.5	-0.7	0.6	0.6	-0.5	-0.7	-0.4	-0.8	-0.2
Basal metabolic rate	0.3	1.4	3.8	-0.8	0.0	1.4	0.8	-1.4	-1.7	-0.2	-0.8	-1.6	1.2	-2.0
Alcohol drinker status: Previous	0.3	0.3	1.3	1.0	-0.0	-0.3	0.4	1.1	0.3	0.6	0.4	0.1	-0.3	0.4
Depression (Nagel 2018)	0.2	0.4	2.1	0.1	0.4	0.4	-0.9	-0.9	0.2	-1.4	0.1	0.2	0.4	-0.5
Major Depression (MDD)	0.2	0.3	1.0	-0.1	0.3	0.5	-0.2	-1.0	-0.5	-0.8	-0.5	-0.3	-0.1	-1.0
Smoking Status	0.2	0.6	2.7	-1.1	0.1	0.5	0.4	-0.4	-0.4	0.4	-0.6	-1.7	0.3	-1.3
Hearing difficulty/problems: Yes	0.2	0.3	1.2	1.1	-0.5	0.3	-0.3	-0.3	-0.2	-0.1	0.5	0.9	-0.1	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	-0.3	0.1	-0.2	0.6	0.6	0.1	1.2	-0.5	-0.2	-0.4	0.6
Medication: Co-codamol	0.2	0.3	1.0	0.3	-0.1	-0.3	-0.2	0.9	0.2	0.4	0.3	0.9	-0.1	1.0
Taking other prescription medications	0.2	0.3	1.2	1.1	-0.0	-0.2	-0.4	0.1	0.5	-0.3	0.4	0.9	0.1	0.7
Trunk fat mass	0.2	0.9	4.3	0.8	-1.1	1.3	1.2	-0.5	-0.8	0.2	0.8	0.2	2.1	-0.5
Neuroticism score	0.2	0.4	0.8	0.7	-0.4	0.9	0.5	-0.9	-0.5	-0.1	0.6	-0.2	0.9	-0.5
Hip circumference	0.2	0.7	2.5	-0.6	-0.6	1.1	0.6	-1.1	-0.9	-0.4	0.0	-0.5	1.6	-1.2
Falls in the last year	0.2	0.2	1.7	0.1	0.4	-0.1	-0.5	-0.3	0.6	-1.3	-0.1	0.3	0.1	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	0.7	-0.5	-0.1	0.6	0.1	-0.8	-0.5	-0.3	-0.1	-0.5	0.8	-0.8
Breastfed as a baby	0.2	0.2	1.1	0.4	-0.1	-0.7	-0.1	-0.3	0.5	0.6	-0.1	0.6	-0.2	1.0
Gout (self-reported)	0.2	0.3	0.5	0.1	-0.6	0.7	0.6	-0.6	-0.5	0.7	0.0	-0.5	0.4	-0.5
Pulse rate, automated reading	0.2	0.5	2.4	0.2	0.3	-1.0	0.2	1.6	0.8	0.6	0.1	0.5	-0.9	1.0
Suffer from ‘nerves’	0.2	0.3	1.1	0.6	-0.5	0.4	-0.0	0.3	-0.2	-0.3	1.0	1.0	0.6	0.6
Smoking status: Previous	0.2	0.3	1.2	-1.1	0.0	0.3	0.2	-0.9	-0.1	0.2	-0.4	-0.9	0.5	-0.9
Whole body fat-free mass	0.2	1.4	3.9	-1.2	0.4	1.1	0.5	-1.3	-1.5	-0.3	-1.3	-1.9	0.7	-2.0
Friendships satisfaction	0.2	0.2	1.0	1.0	-0.0	-0.7	0.0	-0.3	0.7	0.5	0.1	0.2	-0.4	0.6
Osteoarthritis (self-reported)	0.2	0.3	1.9	-0.5	0.5	-0.1	-0.8	0.4	0.2	-1.4	-0.1	0.5	0.4	-0.1
Miserableness	0.2	0.3	0.8	0.4	-0.4	0.9	0.4	-0.9	-0.6	-0.2	0.6	-0.3	0.8	-0.7
Medication: Atorvastatin	0.2	0.3	1.0	1.0	-0.4	0.3	-0.4	-0.1	0.4	-0.5	0.7	0.8	0.4	0.3
Ever smoked	0.2	0.3	1.2	-0.4	0.3	-0.2	0.3	-0.1	0.2	1.0	-0.7	-1.1	-0.4	-0.3
Arm fat-free mass (left)	0.2	0.8	2.0	-1.0	0.4	0.7	0.5	-1.0	-1.0	-0.1	-1.1	-1.4	0.5	-1.4
Average weekly beer plus cider intake	0.2	0.3	1.0	-0.7	0.3	-0.2	0.2	0.8	0.1	0.6	-0.6	-1.0	-0.5	-0.5
Commuting to job workplace: Cycle	0.2	0.3	1.2	0.8	0.3	-0.6	0.1	0.5	0.3	0.7	0.2	0.5	-0.4	1.1
Neuroticism (Nagel 2018)	0.1	0.2	0.6	0.8	-0.4	0.7	0.2	0.3	-0.4	-0.1	0.7	0.6	0.4	0.5
Worry (Nagel 2018)	0.1	0.1	0.4	-0.3	0.6	0.1	-0.4	0.7	-0.3	-0.5	-0.2	-0.2	-0.4	0.0
Hair Pigment	0.1	1.5	3.8	-0.8	1.4	-1.8	-0.7	1.9	1.7	0.1	-1.1	-0.1	-1.5	1.1
Tanning	0.1	1.3	3.7	0.8	-1.2	1.0	1.6	-1.9	-1.7	1.5	0.8	0.2	0.8	0.1
Maternal smoking around birth	0.1	0.1	0.3	-0.3	-0.2	0.4	0.5	0.0	-0.4	0.6	-0.3	-0.4	0.4	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.4	-0.2	0.1	0.2	-0.6	-0.5	-0.2	-0.6	0.1	0.2	-0.3	0.1
Sitting height	0.1	0.8	3.0	1.0	-0.9	0.8	1.7	-0.7	-1.4	0.9	0.8	0.3	0.6	0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.7	0.3	-0.3	0.8	0.0	-0.3	-0.6	-0.1	0.0	-0.4	0.5	-0.8
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	-0.4	-0.1	-0.4	-0.2	-0.3	0.1	0.1	0.3	0.5	-0.1	0.5
Fluid intelligence score	0.1	0.1	0.4	0.4	-0.5	0.1	0.6	-0.3	-0.4	0.6	0.4	0.2	0.4	0.2
Trunk fat-free mass	0.1	0.8	2.2	-1.2	0.8	0.4	0.1	-0.9	-1.0	-0.4	-1.4	-1.5	-0.1	-1.4
Time employed in main current job	0.1	0.2	0.4	0.7	-0.1	-0.2	-0.3	-0.2	0.5	-0.4	0.3	0.6	0.6	0.4
Father’s age at death	0.1	0.2	0.8	0.3	0.0	-0.6	-0.1	-0.0	0.5	-0.0	0.4	0.9	-0.2	0.8
Trunk predicted mass	0.1	0.8	2.1	-1.1	0.7	0.5	0.2	-0.9	-1.0	-0.2	-1.3	-1.5	-0.1	-1.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	-0.6	0.5	-0.1	-0.1	-0.5	-0.1	0.1	-0.5	-0.7	-0.6	-0.4
Arm fat-free mass (right)	0.1	0.7	1.8	-1.1	0.7	0.4	0.2	-0.7	-0.7	-0.3	-1.3	-1.4	0.2	-1.3
Number of full brothers	0.1	0.1	1.0	0.6	-0.2	0.2	0.1	-1.0	0.1	-0.1	0.1	0.1	0.4	-0.1
Worry too long after embarrassment	0.1	0.2	0.4	-0.4	0.4	-0.4	-0.2	0.6	0.6	-0.1	-0.4	-0.6	-0.2	-0.2
Medication: Allopurinol	0.1	0.1	0.9	0.0	-0.3	0.3	0.5	-0.3	-0.2	1.0	-0.1	-0.4	0.2	-0.1
Mean time to correctly identify matches	0.1	0.2	0.8	-0.8	0.2	-0.0	-0.3	0.9	0.4	0.3	-0.4	-0.6	-0.4	-0.1
Arm predicted mass (right)	0.1	0.6	1.8	-1.2	0.9	0.2	0.1	-0.5	-0.5	-0.3	-1.3	-1.3	0.1	-1.1
Average weekly red wine intake	0.1	0.2	0.6	-0.3	0.1	0.2	0.1	-0.8	-0.6	0.3	-0.4	-0.5	-0.4	-0.3
Smoking status: Current	0.1	0.2	0.5	0.3	-0.1	0.3	0.6	-0.2	-0.6	0.7	-0.1	-0.7	-0.2	-0.3
Wears glasses or contact lenses	0.1	0.1	0.8	-0.5	-0.1	0.2	0.3	-0.9	-0.5	0.0	0.0	0.3	0.1	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.7	0.3	0.2	-0.1	0.2	0.4	0.2	0.8	-0.5	-0.3	-0.5	0.4
Ever depressed for a whole week	0.1	0.1	0.3	-0.2	0.0	-0.5	0.1	0.3	0.6	0.6	-0.0	0.2	-0.3	0.6
Unable to work because of sickness or disability	0.1	0.1	0.6	0.8	-0.1	0.0	-0.1	0.2	0.5	-0.4	0.2	0.6	0.1	0.2
Arm predicted mass (left)	0.1	0.6	1.3	-0.8	0.2	0.8	0.6	-0.9	-1.0	-0.0	-0.8	-1.1	0.6	-1.1
Bipolar Disorder (2011)	0.0	0.0	0.1	0.3	-0.2	0.1	0.3	0.0	-0.0	0.3	0.2	0.3	0.0	0.0
Blood Eosinophil Count	0.0	0.1	0.2	0.1	-0.4	-0.1	-0.4	-0.3	0.1	-0.3	0.3	-0.1	0.2	-0.2
Blood Red Count	0.0	0.4	1.5	-0.5	0.7	-0.6	-0.3	0.2	0.6	0.4	-1.2	-0.9	-0.8	-0.3

Hub : Genes

TMEM170A

Models

Trait associations