TWAS
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Usage
Models
Genes
Traits
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Cardiovascular Disease
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chr17:38,092,713-39,502,398
Best TWAS P=5.37e-08 · Best GWAS P=1.03e-07 conditioned to 0.0814
38.2M
38.4M
38.6M
38.8M
39M
39.2M
39.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
SMARCE1
0.07
0.05
lasso
3
0.06
8.0e-08
-4.8
5.4
5.4e-08
-0.78
0.04
0.95
TRUE
3
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
SMARCE1
0.13
0.11
lasso
4
0.11
2.6e-05
5.2
5.3
9.2e-08
-0.51
0.02
0.96
FALSE
1
NTR
Blood
SMARCE1
0.04
0.03
lasso
4
0.04
6.5e-13
5.2
5.2
2.5e-07
-0.54
0.02
0.98
FALSE