Best TWAS P=5.37e-08 · Best GWAS P=1.03e-07 conditioned to 0.0814
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | SMARCE1 | 0.04 | 0.03 | lasso | 4 | 0.04 | 6.5e-13 | 5.2 | 5.2 | 2.5e-07 | -0.54 | 0.02 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SMARCE1 | 0.07 | 0.05 | lasso | 3 | 0.06 | 8.0e-08 | -4.8 | 5.4 | 5.4e-08 | -0.78 | 0.04 | 0.95 | TRUE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SMARCE1 | 0.13 | 0.11 | lasso | 4 | 0.11 | 2.6e-05 | 5.2 | 5.3 | 9.2e-08 | -0.51 | 0.02 | 0.96 | FALSE |