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chr17:42,413,481-43,570,226

Best TWAS P=2.45e-09 · Best GWAS P=1.25e-08 conditioned to 0.0128

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
23	The Cancer Genome Atlas	Thyroid Carcinoma	NMT1	0.18	0.19	enet	20	0.20	3.8e-19	5.5	6.0	2.5e-09	0.63	0.01	0.99	TRUE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NMT1	0.23	0.08	blup	82	0.12	1.1e-05	-5.6	5.9	3.4e-09	0.71	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	HEXIM1	0.05	0.05	blup	47	0.04	8.5e-05	5.4	-5.7	9.3e-09	-0.77	0.02	0.97	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	NMT1	0.09	0.08	lasso	3	0.09	1.1e-09	-5.6	5.7	1.5e-08	0.54	0.01	0.99	FALSE
7	GTEx	Heart Left Ventricle	DCAKD	0.17	0.17	lasso	3	0.17	2.3e-09	5.2	-5.6	2.3e-08	-0.45	0.04	0.96	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	NMT1	0.08	0.04	blup	83	0.05	3.5e-06	5.2	5.6	2.5e-08	0.41	0.03	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NMT1	0.07	0.05	bslmm	323	0.05	1.5e-06	2.9	5.5	3.5e-08	0.42	0.04	0.96	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NMT1	0.05	0.04	lasso	2	0.04	1.5e-05	5.4	5.5	3.8e-08	0.50	0.01	0.98	FALSE
9	GTEx	Nerve Tibial	DCAKD	0.35	0.29	enet	21	0.30	1.6e-21	-5.6	-5.5	4.6e-08	-0.46	0.00	1.00	FALSE
8	GTEx	Muscle Skeletal	DCAKD	0.12	0.06	enet	16	0.07	9.9e-08	4.2	-5.5	4.7e-08	-0.55	0.02	0.98	FALSE
4	GTEx	Breast Mammary Tissue (Male)	DCAKD	0.36	0.29	lasso	8	0.33	1.4e-08	5.1	-5.5	5.0e-08	-0.45	0.04	0.95	FALSE
13	NTR	Blood	DCAKD	0.02	0.01	enet	5	0.01	5.0e-05	-5.6	-5.3	8.7e-08	-0.45	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	NMT1	0.04	0.00	blup	81	0.01	1.9e-02	5.5	5.3	1.5e-07	0.53	0.01	0.87	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	DCAKD	0.12	0.13	lasso	8	0.13	5.5e-13	5.2	-5.2	1.6e-07	-0.34	0.03	0.97	FALSE
10	GTEx	Thyroid	DCAKD	0.25	0.26	enet	17	0.27	9.4e-21	4.2	-5.2	1.7e-07	-0.54	0.16	0.83	FALSE
3	GTEx	Artery Tibial	DCAKD	0.27	0.21	lasso	8	0.20	6.6e-16	5.2	-5.2	1.8e-07	-0.33	0.05	0.95	FALSE
15	The Cancer Genome Atlas	Esophageal Carcinoma	LOC644172	0.19	0.12	lasso	3	0.05	8.2e-03	5.4	-5.2	1.8e-07	-0.28	0.01	0.67	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DCAKD	0.18	0.20	lasso	6	0.20	2.6e-23	5.2	-5.2	2.2e-07	-0.32	0.05	0.95	FALSE
6	GTEx	Esophagus Muscularis	DCAKD	0.27	0.29	lasso	5	0.30	2.1e-18	5.2	-5.2	2.2e-07	-0.36	0.05	0.95	FALSE
11	GTEx	Whole Blood	DCAKD	0.07	0.08	lasso	2	0.06	1.8e-06	5.2	-5.2	2.2e-07	-0.37	0.04	0.95	FALSE
5	GTEx	Esophagus Mucosa	DCAKD	0.33	0.32	enet	20	0.35	5.6e-24	5.2	-5.2	2.5e-07	-0.42	0.05	0.95	FALSE
12	METSIM	Adipose	NMT1	0.13	0.11	lasso	6	0.11	5.7e-16	5.1	5.2	2.5e-07	0.36	0.02	0.97	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	DCAKD	0.26	0.18	enet	27	0.24	8.8e-31	5.2	-5.1	3.1e-07	-0.37	0.05	0.95	FALSE