Best TWAS P=4.69e-09 · Best GWAS P=2.65e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | CTB-31O20.6 | 0.16 | 0.07 | lasso | 5 | 0.05 | 7.8e-04 | -5.9 | -5.9 | 4.7e-09 | 0.99 | 0.01 | 0.99 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | KLF16 | 0.12 | 0.08 | bslmm | 372 | 0.08 | 1.0e-10 | -4.8 | -5.4 | 6.3e-08 | 0.43 | 0.58 | 0.41 | FALSE |