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Cardiovascular Disease
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chr19:7,793,502-9,200,017
Best TWAS P=6.04e-08 · Best GWAS P=3.66e-07 conditioned to 0.605
7.8M
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Muscularis
MARCH2
0.34
0.30
enet
22
0.32
6.9e-20
4.6
5.4
6.0e-08
0.90
0.01
0.97
TRUE
3
GTEx
Nerve Tibial
MARCH2
0.31
0.32
lasso
5
0.35
1.3e-25
4.6
5.2
2.4e-07
0.93
0.01
0.98
FALSE
1
GTEx
Artery Tibial
MARCH2
0.36
0.37
lasso
5
0.44
5.0e-37
5.1
5.1
3.1e-07
0.95
0.00
0.99
FALSE