Best TWAS P=6.04e-08 · Best GWAS P=3.66e-07 conditioned to 0.605
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | MARCH2 | 0.36 | 0.37 | lasso | 5 | 0.44 | 5.0e-37 | 5.1 | 5.1 | 3.1e-07 | 0.95 | 0.00 | 0.99 | FALSE |
2 | GTEx | Esophagus Muscularis | MARCH2 | 0.34 | 0.30 | enet | 22 | 0.32 | 6.9e-20 | 4.6 | 5.4 | 6.0e-08 | 0.90 | 0.01 | 0.97 | TRUE |
3 | GTEx | Nerve Tibial | MARCH2 | 0.31 | 0.32 | lasso | 5 | 0.35 | 1.3e-25 | 4.6 | 5.2 | 2.4e-07 | 0.93 | 0.01 | 0.98 | FALSE |