Best TWAS P=6.03e-10 · Best GWAS P=2.63e-07 conditioned to 1.96e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | TSPY26P | 0.08 | 0.01 | lasso | 4 | 0.03 | 1.7e-03 | -5.0 | -6.2 | 6.0e-10 | -0.10 | 0.03 | 0.88 | TRUE |
| 6 | NTR | Blood | C20orf160 | 0.01 | 0.00 | bslmm | 305 | 0.00 | 8.0e-03 | -4.2 | 5.4 | 5.8e-08 | 0.10 | 0.05 | 0.06 | TRUE |
| 2 | GTEx | Artery Aorta | KIF3B | 0.15 | 0.00 | enet | 33 | 0.00 | 2.9e-01 | -1.9 | 5.8 | 5.3e-09 | 0.07 | 0.04 | 0.20 | FALSE |
| 3 | GTEx | Brain Cerebellum | TSPY26P | 0.25 | 0.06 | lasso | 6 | 0.15 | 2.9e-05 | 3.9 | -5.8 | 6.3e-09 | -0.09 | 0.05 | 0.48 | FALSE |
| 5 | GTEx | Thyroid | TSPY26P | 0.12 | 0.08 | enet | 18 | 0.08 | 7.2e-07 | -4.5 | -5.7 | 1.5e-08 | -0.19 | 0.05 | 0.93 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TM9SF4 | 0.06 | 0.05 | lasso | 3 | 0.05 | 4.4e-06 | -4.9 | 5.3 | 1.3e-07 | 0.17 | 0.01 | 0.97 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TSPY26P | 0.07 | 0.03 | lasso | 5 | 0.04 | 5.2e-04 | -4.6 | -5.2 | 1.7e-07 | -0.35 | 0.06 | 0.88 | FALSE |