Best TWAS P=6.93e-21 · Best GWAS P=4.69e-37 conditioned to 0.00165
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | 12.6 | -9.4 | 6.9e-21 | -0.69 | 0.01 | 0.65 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TH1L | 0.07 | 0.00 | blup | 46 | 0.02 | 2.8e-02 | -4.4 | 5.6 | 2.6e-08 | 0.25 | 0.02 | 0.42 | TRUE |
| 3 | GTEx | Nerve Tibial | NELFCD | 0.30 | 0.17 | enet | 25 | 0.23 | 2.8e-16 | -4.4 | 5.4 | 5.3e-08 | 0.27 | 1.00 | 0.00 | TRUE |
| 1 | GTEx | Adipose Subcutaneous | NELFCD | 0.43 | 0.31 | enet | 36 | 0.38 | 3.3e-33 | -4.4 | 5.2 | 2.0e-07 | 0.15 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Esophagus Mucosa | NELFCD | 0.32 | 0.20 | enet | 8 | 0.27 | 2.1e-18 | -4.4 | 5.3 | 1.3e-07 | 0.21 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TH1L | 0.16 | 0.00 | enet | 14 | 0.08 | 3.4e-04 | -5.1 | 5.2 | 2.5e-07 | 0.19 | 0.02 | 0.54 | FALSE |