TWAS
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Cardiovascular Disease
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chr1:115,486,678-116,932,921
Best TWAS P=9.81e-08 · Best GWAS P=1.88e-17 conditioned to 2.03e-15
115.6M
115.8M
116M
116.2M
116.4M
116.6M
116.8M
117M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
VANGL1
0.18
0.03
enet
23
0.03
0.0032
-1.1
5.3
9.8e-08
0.12
0.18
0.05
TRUE