TWAS hub - VANGL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0490	0.0190	2.2e-03	0.018	0.020	0.017	0.018	0.022	2.7e-03	1.7e-03	3.2e-03	2.4e-03	9.9e-04
2	GTEx	Adipose Subcutaneous	0.2230	0.0440	3.6e-09	0.218	NA	0.206	NA	0.213	1.1e-17	NA	1.0e-16	NA	3.0e-17
3	GTEx	Artery Tibial	0.1780	0.0515	2.0e-04	0.028	NA	0.027	NA	0.009	2.6e-03	NA	3.2e-03	NA	6.3e-02
4	GTEx	Esophagus Mucosa	0.2080	0.0630	4.2e-04	0.071	NA	0.117	NA	0.108	1.7e-05	NA	3.1e-08	NA	1.1e-07
5	GTEx	Esophagus Muscularis	0.1930	0.0590	3.4e-04	0.019	NA	0.066	NA	0.061	2.5e-02	NA	7.5e-05	NA	1.5e-04
6	GTEx	Liver	0.4380	0.1080	1.3e-03	0.195	NA	0.210	NA	0.175	4.1e-06	NA	1.6e-06	NA	1.3e-05
7	GTEx	Lung	0.1017	0.0392	2.9e-03	0.094	NA	0.101	NA	0.097	1.2e-07	NA	3.6e-08	NA	6.8e-08
8	GTEx	Nerve Tibial	0.1362	0.0397	3.4e-04	0.099	NA	0.079	NA	0.100	1.7e-07	NA	3.1e-06	NA	1.4e-07
9	GTEx	Ovary	0.2790	0.0940	2.5e-03	-0.012	NA	0.038	NA	-0.003	9.4e-01	NA	4.1e-02	NA	3.8e-01
10	GTEx	Pancreas	0.2030	0.0660	3.0e-03	0.135	NA	0.113	NA	0.125	2.6e-06	NA	1.8e-05	NA	6.4e-06
11	GTEx	Small Intestine Terminal Ileum	0.6590	0.1320	3.4e-04	0.087	NA	0.152	NA	0.326	5.6e-03	NA	2.9e-04	NA	4.4e-08
12	GTEx	Thyroid	0.1030	0.0390	3.0e-03	0.050	NA	0.051	NA	0.054	1.1e-04	NA	8.8e-05	NA	5.9e-05
13	GTEx	Whole Blood	0.0850	0.0320	7.2e-03	-0.001	NA	0.003	NA	0.008	3.8e-01	NA	1.5e-01	NA	5.2e-02
14	METSIM	Adipose	0.1640	0.0317	0.0e+00	0.157	0.138	0.161	0.170	0.159	8.4e-23	5.2e-20	2.5e-23	1.0e-24	4.0e-23
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0452	0.0226	7.0e-03	0.027	0.018	0.024	NA	0.019	4.7e-04	3.5e-03	9.9e-04	NA	3.2e-03
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0437	0.0218	7.7e-03	0.002	0.016	0.001	NA	0.001	1.9e-01	6.2e-03	2.1e-01	NA	2.5e-01
17	TCGA	Brain Lower Grade Glioma	0.0562	0.0278	6.4e-03	0.003	0.030	0.012	NA	0.002	1.5e-01	2.0e-04	1.4e-02	NA	1.7e-01
18	TCGA	Prostate Adenocarcinoma	0.1243	0.0438	1.2e-07	0.084	0.068	0.061	NA	0.071	3.9e-09	1.3e-07	5.1e-07	NA	6.2e-08
19	TCGA	Thyroid Carcinoma	0.0460	0.0220	5.4e-03	0.032	0.009	0.022	NA	0.028	4.0e-04	4.4e-02	3.1e-03	NA	9.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Tinnitus: Yes, now most or all of the time	5.3	6.2	13.6	-2.5	-3.1	-1.2	-1.4	-1.6	-3.3	-3.1	-3.5	-0.6	-3.1	-0.4	-3.7	-2.9	-3.2	-2.1	-0.9	-0.5	-2.1	-3.1
Eye problems/disorders: None of the above	3.4	3.9	9.7	-0.5	-2.0	-2.0	-0.0	-2.5	-1.3	-1.7	-2.6	-1.9	-3.1	-2.1	-2.5	-3.0	-1.9	-1.8	-1.7	-1.4	-0.8	-2.0
Alzheimer’s Disease (in father)	2.7	2.9	6.9	2.2	2.1	0.9	1.1	1.1	2.5	2.6	2.0	0.8	1.6	0.3	2.1	1.5	2.0	1.4	0.3	1.2	1.6	2.1
Bipolar Disorder (2018)	2.6	4.0	7.7	-0.2	-2.7	-1.2	-1.0	-1.7	-2.3	-1.6	-1.8	-0.6	-2.2	-0.9	-2.7	-2.2	-2.7	-2.5	-2.4	-2.4	-1.4	-2.8
Commuting to job workplace: Walk	2.6	2.8	7.1	2.0	1.7	1.9	2.4	0.2	0.9	2.2	0.8	2.7	1.3	1.2	1.6	1.1	1.6	2.0	2.2	-0.3	1.9	1.7
Ever highly irritable/argumentative for 2 days	2.4	2.9	5.7	2.1	2.2	1.0	1.1	0.9	2.2	1.8	2.0	1.1	1.5	0.4	2.3	1.6	2.2	2.0	1.4	-0.9	1.0	2.4
Time employed in main current job	2.3	2.7	11.2	-0.9	1.5	1.4	1.2	1.3	1.8	1.0	1.4	-0.2	1.6	-2.7	1.7	1.8	1.5	0.8	0.4	3.3	2.0	1.5
Exposure to tobacco smoke at home	2.3	2.5	8.1	-0.3	1.5	0.9	1.9	1.8	1.9	1.3	0.7	-0.9	0.9	-2.8	1.2	0.7	1.6	1.6	0.8	2.1	2.8	1.5
Type 2 Diabetes (T2D) (2018)	2.2	4.2	10.7	1.6	2.1	2.8	-0.4	1.7	2.6	2.0	2.8	-0.8	3.0	0.1	2.7	3.3	2.2	1.1	1.3	1.1	1.8	1.9
Hearing difficulty/problems: Yes	2.2	3.3	12.1	-2.1	-2.2	0.5	-3.5	-0.5	-2.3	-2.4	-1.4	1.3	-1.1	-1.1	-2.1	-1.0	-2.4	-2.2	-1.3	-0.2	-0.8	-2.3
Pain type(s) experienced in last month: Hip pain	2.2	2.7	6.7	-0.4	1.9	1.3	0.8	2.2	1.7	0.8	2.2	-1.3	1.7	-0.5	1.9	1.6	1.9	1.6	1.2	2.6	1.9	1.9
Multivitamins +/- minerals	2.1	2.7	7.5	1.9	1.9	1.1	1.9	-0.3	1.4	1.5	1.2	0.4	1.6	1.6	1.8	1.8	2.0	2.0	2.7	0.4	1.2	2.0
Medication: Bendroflumethiazide	2.1	3.2	11.6	1.6	1.7	2.9	1.1	0.5	1.2	1.1	1.8	-0.5	2.0	3.4	1.9	2.2	1.9	1.1	2.3	1.5	0.0	1.8
Noisy workplace	1.9	2.3	5.5	-1.8	-1.7	-1.8	-1.8	-0.7	-2.1	-2.0	-0.3	-0.6	-1.1	1.4	-1.7	-0.9	-1.9	-1.1	-0.7	-1.0	-2.3	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.5	7.3	1.0	-1.4	-2.0	-1.2	-2.1	-1.0	-0.8	-1.0	-0.3	-1.7	0.7	-1.5	-1.6	-1.4	-1.5	-1.9	-2.7	-2.5	-1.4
Number of operations (self-reported)	1.8	2.7	7.7	-0.8	1.8	2.3	1.1	2.8	0.5	0.8	1.7	0.8	1.4	0.4	1.8	0.9	1.7	1.8	2.4	2.4	1.4	1.8
Rheumatoid Arthritis	1.7	2.4	6.6	-0.3	1.9	0.4	0.4	2.5	1.1	0.9	2.6	-1.2	2.1	0.0	2.1	2.1	1.9	1.6	0.9	1.1	-0.1	1.7
Had major operations	1.7	2.0	4.5	0.3	1.5	2.1	0.2	1.3	1.2	1.3	2.1	1.1	1.8	-0.8	2.0	1.4	1.6	0.8	1.5	1.2	1.0	1.6
Eye problems/disorders: Cataract	1.7	2.0	6.3	1.0	1.3	2.5	0.4	1.4	0.9	1.4	1.3	2.1	1.6	1.2	1.5	1.4	1.3	1.2	1.2	1.4	1.1	1.3
Hair/balding pattern: Pattern 4	1.6	3.9	7.0	1.3	2.2	1.6	2.5	0.9	2.6	2.6	2.2	1.4	1.9	1.1	2.3	1.6	2.5	2.4	2.3	0.3	1.4	2.4
Emphysema/chronic bronchitis	1.6	1.8	6.8	0.6	-1.4	-1.1	-0.9	-2.6	-0.8	-1.3	-1.4	0.4	-1.3	0.7	-1.4	-1.4	-1.5	-1.4	-1.6	-1.6	-1.1	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	3.8	-0.3	-1.6	-1.3	-1.8	-1.4	-1.2	-1.9	-0.7	-0.9	-1.0	-0.8	-1.2	-0.9	-1.7	-2.0	-1.4	-1.5	-1.5	-1.6
Verbal and Numeric Reasoning (VNR)	1.5	3.6	10.9	-1.5	1.8	-1.6	2.7	2.2	2.0	0.9	-0.2	-2.7	-0.0	-3.1	1.2	-0.1	1.9	2.3	0.6	1.6	3.3	1.9
HDL Cholesterol	1.5	2.4	6.9	1.5	1.6	1.0	0.9	1.0	1.7	1.2	2.0	2.6	1.8	0.8	1.8	1.8	1.5	1.5	1.9	0.5	1.4	1.6
Triglycerides	1.5	2.5	4.2	-1.4	-1.9	-1.5	-0.9	-1.1	-1.6	-1.0	-1.9	-1.5	-2.0	0.7	-2.0	-2.0	-1.9	-1.8	-1.4	-0.2	-2.0	-1.8
Supplements: Zinc	1.5	1.6	7.6	2.8	0.7	1.1	-1.3	-1.9	0.8	0.7	1.6	1.2	1.6	1.3	1.1	1.4	0.5	0.0	1.0	-1.4	0.1	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.4	0.3	1.5	0.5	0.9	1.3	0.9	1.2	1.2	-0.7	1.5	-0.7	1.8	1.5	1.4	1.2	1.1	1.4	2.1	1.4
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	8.3	-1.1	-1.8	-0.7	-2.9	-0.8	-2.6	-2.5	-0.4	-0.3	-0.6	0.9	-1.4	-0.6	-1.7	-1.9	-0.5	-0.5	-2.0	-1.7
Average weekly champagne plus white wine intake	1.5	2.1	6.4	2.5	1.9	1.4	1.5	-0.1	1.0	0.8	1.4	0.9	1.3	1.3	1.5	1.5	2.0	2.0	1.0	-0.4	0.8	1.8
Breast Cancer	1.4	3.4	6.7	2.2	2.3	2.6	1.1	-0.2	2.5	2.1	1.6	1.2	1.7	0.5	2.2	1.5	2.2	2.1	2.3	0.3	1.6	2.3
Hearing difficulty/problems with background noise	1.4	2.3	7.1	-1.6	-1.9	0.1	-2.7	-0.9	-1.1	-1.6	-0.1	0.0	-0.3	-2.0	-1.4	-0.2	-1.9	-2.0	-1.4	-2.1	-1.0	-2.0
Prospective memory result	1.4	1.7	5.9	1.8	1.2	0.4	-0.4	0.2	0.7	0.7	1.7	-0.2	2.2	0.8	1.7	2.4	1.2	0.8	1.6	-0.1	1.7	1.2
Qualifications: nursing, teaching	1.4	2.2	6.8	1.0	1.8	2.5	0.4	0.5	1.5	2.6	1.9	-0.1	1.6	-0.5	1.9	1.6	1.8	1.4	0.6	0.1	1.4	1.7
Average weekly beer plus cider intake	1.4	2.0	3.6	-0.6	-1.9	-1.5	-1.3	-1.5	-0.4	-1.0	-1.4	-1.3	-1.8	-0.4	-1.8	-1.8	-1.7	-1.8	-1.9	-0.6	-0.7	-1.8
Commuting to job workplace: Cycle	1.4	1.7	5.6	-0.3	-1.4	-2.4	-1.1	-1.2	-1.3	-0.5	-1.4	-0.7	-1.1	-1.2	-1.4	-1.4	-1.5	-1.8	-1.6	-0.1	-0.8	-1.4
Average weekly red wine intake	1.3	1.9	4.5	-0.1	1.8	1.5	0.8	2.1	1.5	1.4	1.2	0.2	1.1	-1.4	1.7	1.0	1.8	1.4	0.3	1.8	0.5	1.7
Lupus	1.2	1.9	5.1	-0.2	-1.3	-1.0	-0.2	-2.0	-1.3	-1.0	-2.1	-0.9	-1.9	-1.2	-1.6	-1.9	-1.3	-0.7	-0.6	-2.2	-0.3	-1.4
Type 2 Diabetes (T2D) (2012)	1.2	1.3	10.3	-0.6	0.9	0.3	3.2	1.2	0.9	0.4	-0.9	0.1	-0.7	-0.9	0.3	-0.8	0.5	2.1	1.2	0.9	1.2	0.4
Waist Hip Ratio (WHR)	1.2	5.3	13.0	0.8	2.1	2.3	0.6	2.8	2.1	2.2	3.1	3.3	3.3	-0.1	2.5	3.6	1.9	1.6	2.5	1.2	2.2	2.0
Medication for hormone replacement therapy	1.2	1.3	3.8	-1.6	-1.3	-0.5	-0.9	0.6	-1.0	-2.0	-1.2	-0.1	-1.0	-0.6	-1.3	-0.9	-1.3	-1.1	-0.7	0.8	-1.8	-1.4
Vitamin and mineral supplements	1.2	1.6	7.1	-2.7	-0.9	-0.7	-0.4	1.8	-0.1	-1.2	-0.9	-1.7	-0.9	-1.8	-0.9	-0.9	-0.6	-0.9	-1.9	1.5	-0.5	-0.9
Medication: Atenolol	1.2	1.5	4.2	-0.9	0.3	1.7	-1.1	1.5	0.3	0.7	2.0	-0.6	2.0	-1.9	1.0	2.0	0.7	0.3	0.4	-0.2	1.5	0.3
Past tobacco smoking	1.2	2.1	3.6	1.6	1.7	1.6	1.6	1.0	1.1	1.1	1.4	1.1	1.9	-0.4	1.7	1.7	1.9	1.6	1.3	0.4	1.8	1.7
Trunk fat-free mass	1.2	6.6	13.8	0.4	-2.6	-2.2	-1.2	-3.5	-1.6	-2.7	-3.1	-3.7	-3.6	-1.6	-3.1	-3.5	-2.4	-2.0	-2.5	-2.7	-0.9	-2.6
Trunk predicted mass	1.2	6.7	13.8	0.3	-2.6	-2.2	-1.2	-3.4	-1.6	-2.7	-3.1	-3.7	-3.6	-1.6	-3.1	-3.5	-2.5	-2.0	-2.5	-2.7	-0.9	-2.6
Medication: Ibuprofen	1.2	1.5	5.8	0.7	-0.7	-2.2	-1.0	-1.5	-0.7	-0.8	-0.1	-0.5	-1.0	0.9	-0.8	-1.0	-0.9	-0.7	-1.2	-2.3	-2.4	-0.9
Mood swings	1.2	2.2	9.3	0.9	1.0	0.8	-1.4	0.1	1.7	1.7	3.1	-0.4	2.4	-0.5	1.8	2.6	1.1	0.7	0.1	-1.2	0.8	1.2
Eye problems/disorders: Glaucoma	1.2	1.4	6.9	-0.2	0.2	0.5	-1.8	1.2	-0.1	-0.7	1.7	0.3	1.9	2.6	0.9	2.1	0.4	-0.1	0.8	0.4	-1.3	0.3
Ever smoked	1.2	2.2	5.7	-1.7	-1.7	-1.0	-1.7	-0.9	-1.4	-1.4	-1.6	-0.8	-1.7	1.7	-1.7	-1.4	-1.8	-1.3	-0.5	0.2	-2.4	-1.6
Fasting Glucose	1.1	1.3	5.1	-1.0	1.2	1.9	0.6	0.9	1.4	0.7	0.9	0.5	1.0	-0.7	1.2	0.6	1.6	2.3	0.6	0.7	0.9	1.6
Schizophrenia (2014)	1.1	2.5	7.0	0.7	-1.7	-0.2	0.0	-2.3	-1.8	-2.1	-1.3	1.0	-1.4	1.3	-1.6	-1.5	-1.5	-1.5	-1.4	-1.8	-2.6	-1.8
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.8	-0.1	1.2	1.0	0.5	2.2	0.7	0.8	1.0	1.9	1.1	0.3	1.3	0.7	1.1	1.1	1.0	1.5	1.4	1.3
Hair/balding pattern: Pattern 3	1.1	1.7	10.4	-1.5	-1.1	1.1	-3.2	0.1	-0.8	-1.7	-0.2	-1.0	0.4	0.2	-0.7	0.5	-1.1	-1.5	-1.0	1.6	-1.6	-1.2
Blood clot in the leg (DVT)	1.1	1.5	4.3	-0.3	-1.1	-1.6	0.0	-1.2	-1.1	-1.2	-1.6	-0.9	-1.9	0.0	-1.4	-2.1	-1.2	-0.9	-1.2	-0.6	-0.9	-1.2
Glaucoma (self-reported)	1.1	1.3	4.5	0.1	0.8	0.5	-1.2	1.4	0.1	-0.4	1.8	-0.2	1.8	2.1	1.3	1.9	0.9	0.5	1.3	-0.3	-0.6	0.8
Medication: Blood pressure	1.1	1.9	9.6	0.1	1.0	3.1	1.7	0.6	1.2	0.8	1.0	0.6	1.7	0.2	1.3	1.5	1.3	1.1	1.9	1.5	1.4	1.0
Ever taken oral contraceptive pill	1.1	1.2	7.4	2.7	1.1	0.9	1.3	-0.0	0.9	1.4	0.1	0.2	0.2	0.7	0.7	0.1	1.0	1.4	0.5	-2.0	0.7	0.9
Arm predicted mass (left)	1.1	5.4	11.5	0.0	-2.4	-1.9	-1.2	-3.0	-1.6	-2.6	-2.8	-3.2	-3.4	-1.2	-2.9	-3.3	-2.3	-1.9	-1.8	-2.3	-0.9	-2.3
Bipolar Disorder or Schizophrenia	1.0	2.4	4.4	1.3	-1.7	0.2	0.5	-2.1	-1.6	-1.2	-1.6	0.6	-1.5	0.1	-1.8	-1.7	-1.5	-1.9	-1.9	-1.9	-1.9	-1.9
Alzheimer’s Disease (in mother)	1.0	1.2	5.7	-0.6	-0.8	-2.4	-0.3	-1.0	0.2	-0.9	-1.1	-0.3	-1.2	-1.7	-0.9	-1.4	-0.9	-0.6	-1.4	-1.5	-0.5	-0.8
Prostate Cancer	1.0	1.4	7.4	0.8	0.7	0.3	-0.1	0.1	0.7	0.5	1.8	2.7	1.6	1.8	1.1	1.8	0.8	-0.1	1.0	1.4	-0.3	0.8
Cardiovascular Disease	1.0	3.4	28.4	0.7	1.0	5.3	1.4	1.0	1.1	1.1	1.0	1.3	1.4	1.3	1.2	1.6	1.5	0.8	2.5	2.9	1.0	1.0
Angina	1.0	1.3	8.4	0.1	0.4	2.9	-0.1	0.5	-0.3	1.3	1.6	1.0	1.5	1.0	0.8	1.4	0.6	0.3	1.9	0.6	0.5	0.4
Hayfever, allergic rhinitis or eczema	1.0	2.3	6.7	0.3	1.5	2.1	2.2	0.9	0.8	2.6	0.3	2.4	0.6	0.6	1.0	0.6	1.5	1.5	2.1	2.1	0.6	1.4
Nervous feelings	1.0	1.9	4.7	-1.5	-1.6	-1.0	-1.3	-0.3	-2.2	-1.5	-1.5	-0.0	-1.5	-1.0	-1.6	-1.5	-1.8	-1.3	-1.8	0.0	-0.6	-1.4
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	2.9	-0.6	-1.1	-0.7	-0.7	-1.4	-1.2	-1.7	-0.9	-0.6	-1.3	1.6	-1.3	-1.3	-1.2	-0.4	0.3	-0.7	-1.3	-1.1
Impedance of arm (right)	1.0	4.5	11.9	1.0	2.0	2.3	1.2	1.8	0.7	3.0	2.3	3.5	3.1	1.4	2.4	3.2	2.0	1.4	2.0	1.7	0.5	1.9
Illnesses of mother	1.0	1.2	4.9	-1.3	0.7	-0.4	0.8	1.1	0.9	1.1	0.6	0.4	0.4	-2.2	0.8	0.2	0.7	0.5	1.1	1.8	2.0	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	7.4	0.2	-1.9	-2.6	-1.5	-2.0	-0.9	-1.3	-1.4	-2.4	-1.6	-1.1	-1.8	-1.5	-1.8	-1.7	-2.2	-2.7	-1.2	-1.7
Impedance of arm (left)	1.0	4.6	10.8	0.9	2.1	2.1	1.3	2.0	1.0	3.3	2.3	3.0	3.1	1.0	2.5	3.2	2.0	1.5	2.1	1.6	0.8	2.0
Neck or shoulder pain in last month	1.0	1.4	4.4	0.5	-1.4	-0.7	-2.1	-2.1	-0.7	-0.1	0.1	-1.7	-0.3	0.3	-1.0	-0.4	-1.5	-2.1	-1.2	-0.6	-0.8	-1.3
Angina (self-reported)	1.0	1.3	8.0	-0.2	0.4	2.8	-0.1	0.6	-0.6	1.0	1.6	1.0	1.5	0.9	0.7	1.5	0.5	0.3	2.0	0.6	0.5	0.3
Arm predicted mass (right)	1.0	5.1	12.2	0.3	-2.2	-1.8	-1.1	-2.8	-1.4	-2.4	-2.7	-3.5	-3.3	-1.4	-2.7	-3.3	-2.1	-1.7	-1.6	-2.4	-0.4	-2.2
Commuting to job workplace: Public transport	1.0	1.2	3.9	1.2	-1.2	-0.7	-1.5	-2.0	-0.1	-0.7	-0.9	0.3	-0.3	0.7	-0.8	-0.5	-1.1	-1.3	-1.0	-1.7	-1.4	-1.1
Depression (Nagel 2018)	0.9	1.4	6.6	1.2	1.1	0.1	0.7	-0.9	1.1	1.6	1.3	2.6	1.2	-1.3	1.3	1.2	0.8	0.8	0.8	-0.2	0.8	1.1
Body Mass Index (BMI) (2010)	0.9	1.2	4.4	-1.1	-1.0	-0.9	-1.4	-0.4	-1.0	-0.9	-1.0	-2.1	-0.9	-1.1	-1.1	-0.5	-1.0	-0.7	-2.0	-0.9	0.1	-1.0
Fed-up feelings	0.9	1.6	4.3	-0.4	1.1	0.4	-0.2	1.5	2.1	1.5	2.0	-0.7	1.7	-0.8	1.6	1.8	1.1	1.0	0.3	1.2	0.8	1.3
High blood pressure	0.9	2.5	26.0	0.7	0.5	5.1	0.9	0.7	0.8	0.6	0.3	1.7	0.8	1.1	0.6	0.9	0.8	0.4	1.9	2.5	0.7	0.5
Had menopause	0.9	1.1	2.2	-1.1	-0.9	-1.3	0.3	0.9	-1.4	0.3	-1.5	1.4	-1.4	1.4	-1.1	-1.5	-1.1	-0.2	0.4	0.9	-0.7	-0.7
Depression (self-reported)	0.9	1.1	2.5	0.5	-1.2	-1.3	-1.0	-1.6	-1.0	-0.6	-0.6	0.7	-0.8	1.1	-1.0	-0.8	-1.4	-1.6	0.2	-1.0	-0.9	-1.2
Gout (self-reported)	0.9	1.2	2.7	0.1	-1.3	-0.6	-0.5	-0.9	-0.9	-1.6	-1.2	-0.9	-1.2	1.4	-1.4	-1.2	-1.1	-1.4	-0.1	-0.4	-1.5	-1.4
Forced vital capacity (FVC), Best measure	0.9	3.3	7.7	-0.5	-2.1	-2.8	-1.4	-1.9	-1.5	-1.6	-1.6	-2.2	-1.8	-0.2	-2.0	-1.6	-2.0	-1.8	-2.0	-2.0	-2.0	-2.0
Arm fat-free mass (right)	0.9	4.7	12.5	0.1	-2.1	-1.8	-1.0	-2.6	-1.3	-2.3	-2.5	-3.5	-3.1	-1.6	-2.6	-3.1	-2.0	-1.6	-1.7	-2.3	-0.4	-2.0
Number of full sisters	0.9	1.1	6.8	-2.6	0.2	0.8	-0.3	1.4	0.2	-0.4	-0.2	0.1	0.4	-1.9	0.1	0.2	-0.0	0.7	0.5	2.2	1.0	0.2
Chest pain or discomfort	0.9	1.3	6.6	0.8	-0.5	0.3	-1.9	-0.1	-0.6	1.2	1.8	-0.6	1.2	-1.2	0.2	1.1	-0.4	-1.2	-1.3	-2.6	0.5	-0.6
Hypertension (Self-reported)	0.9	2.5	25.1	0.4	0.5	5.0	1.0	1.0	0.6	0.8	0.5	1.7	1.0	1.2	0.6	1.2	0.9	0.7	2.2	2.3	0.5	0.6
Illnesses of father: Heart disease	0.9	1.2	4.5	0.1	-0.9	-0.7	-0.2	-1.6	-2.1	-0.8	-0.8	-0.6	-1.4	-1.5	-1.1	-1.4	-1.0	-1.4	-0.4	-1.1	-0.1	-1.1
Whole body fat-free mass	0.9	4.9	14.9	0.3	-2.1	-1.8	-1.1	-3.1	-1.2	-2.2	-2.5	-3.9	-3.0	-1.5	-2.6	-2.9	-1.9	-1.7	-2.1	-2.5	-0.6	-2.1
Medication: Blood pressure	0.9	1.7	9.9	0.7	0.8	3.1	0.9	0.7	0.9	0.6	0.5	1.1	0.9	2.8	0.8	0.9	1.1	0.8	1.4	1.4	-0.1	0.9
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.4	-0.5	-1.0	-1.5	-0.1	-0.9	-1.0	-1.2	-1.5	-1.0	-1.6	-0.5	-1.3	-1.9	-1.1	-0.8	-1.1	-0.6	-0.7	-1.1
Heart disease (siblings)	0.9	1.1	3.8	-0.2	0.9	-0.2	1.8	1.2	1.2	1.0	-0.4	0.8	-0.1	-1.4	0.7	0.0	0.8	1.1	1.4	0.8	1.9	1.0
Major Depression (MDD)	0.8	0.9	4.6	0.9	-0.7	-0.4	-0.4	-1.4	-2.1	-0.8	-0.5	-0.2	-0.6	1.6	-0.8	-0.6	-0.9	-0.5	0.3	-1.6	-0.7	-0.7
Bipolar Disorder (2011)	0.8	0.7	3.5	1.0	-0.3	0.3	1.4	-0.6	-0.3	0.6	-1.4	0.9	-1.6	-0.0	-0.6	-1.9	-0.2	-0.1	0.4	-0.6	0.6	-0.2
Coronary Artery Disease (CAD)	0.8	0.9	11.8	0.2	0.0	0.5	0.2	-0.1	0.2	1.4	0.6	3.4	1.0	0.6	0.3	0.2	0.1	0.2	1.0	0.1	-0.4	0.5
Average weekly spirits intake	0.8	1.0	4.3	0.4	-0.4	-0.6	-1.9	-0.5	-0.2	-0.9	1.1	-2.1	0.9	0.1	0.3	1.0	-0.3	-1.2	-1.2	-1.0	-1.6	-0.4
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.4	1.0	0.4	0.7	-1.4	-0.3	1.2	0.6	1.5	-0.5	1.5	-0.0	0.9	1.5	0.5	0.2	0.8	0.4	1.2	0.5
Diabetes (father)	0.8	1.0	4.3	0.7	-0.8	-1.1	-0.7	-2.1	-0.8	0.0	0.2	-1.8	-0.2	0.2	-0.5	-0.4	-0.9	-1.5	-1.0	-1.6	-0.1	-0.9
Current tobacco smoking	0.8	1.3	4.8	-1.3	0.8	-0.1	0.4	0.5	0.9	0.3	0.9	1.6	1.1	2.2	0.9	0.9	0.7	1.3	1.7	1.1	-1.5	0.9
Medication: Levothyroxine sodium	0.8	1.3	5.2	0.4	1.0	0.9	-1.3	0.4	1.0	1.1	2.3	-0.1	1.7	-0.8	1.5	1.5	0.9	-0.1	0.1	0.7	1.6	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.9	1.0	1.1	-0.4	0.3	0.5	1.6	1.3	1.7	0.3	1.3	-0.7	1.4	1.3	1.1	1.0	-0.1	-1.4	1.3	1.3
Had other major operations	0.8	0.9	3.2	-0.6	-0.9	-0.8	0.2	0.3	-1.7	-1.0	-1.1	-0.5	-1.4	0.5	-1.3	-1.8	-1.1	-0.5	-0.2	-0.2	-0.8	-1.0
Medication: Simvastatin	0.8	1.2	7.9	0.3	0.6	2.8	-0.4	0.3	0.2	0.4	0.9	1.0	1.1	1.6	0.8	1.0	0.8	0.3	1.7	1.6	0.5	0.7
Falls in the last year	0.8	1.1	2.8	-0.4	-1.4	0.0	-1.2	-1.4	-0.9	-1.0	-0.6	-0.6	-0.8	-1.5	-1.4	-0.8	-1.6	-1.7	-0.4	-0.3	0.4	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.0	-0.1	-1.2	-0.5	-1.7	-2.0	-1.5	-1.1	-0.1	-0.4	-0.4	-0.1	-1.0	-0.4	-1.4	-1.2	-0.6	-1.6	-0.7	-1.3
Number of children fathered	0.8	0.9	2.4	-1.4	-1.2	-0.2	-1.3	-0.0	-1.5	-1.4	0.2	-1.3	0.1	-0.7	-0.9	0.3	-1.0	-1.6	-0.7	0.6	0.1	-1.1
Pulse wave peak to peak time	0.8	1.0	9.7	-0.2	-0.0	-0.4	0.2	-0.9	-0.1	1.0	-0.4	-1.0	-0.3	-3.1	0.1	-0.4	-0.2	-0.1	-1.4	-1.4	1.1	-0.1
Health satisfaction	0.8	1.1	2.6	1.4	1.1	0.7	1.0	-0.2	1.3	1.4	0.8	0.9	0.9	0.8	1.1	0.9	1.0	0.9	1.6	0.6	0.9	1.2
Shortness of breath walking on level ground	0.8	0.9	4.9	1.8	-0.3	1.2	-0.3	-1.4	-0.7	0.6	0.1	1.5	-0.2	2.2	-0.3	-0.3	-0.3	-0.4	-0.0	-1.1	-1.3	-0.3
Age at last live birth	0.8	1.2	5.1	2.1	0.5	-0.7	0.9	-0.9	1.0	1.4	0.8	0.9	0.0	-1.5	0.6	-0.2	0.4	0.3	-0.6	-2.3	1.6	0.6
Breast cancer (self-reported)	0.8	0.9	3.6	-0.1	-0.7	0.0	0.6	0.4	-1.9	-0.4	-1.6	0.6	-1.2	0.0	-1.1	-1.1	-0.9	-0.3	-1.9	0.4	-0.5	-0.8
Whole body water mass	0.8	4.7	13.3	0.4	-2.1	-1.7	-1.0	-3.1	-1.1	-2.1	-2.5	-3.6	-3.0	-1.6	-2.5	-2.9	-1.9	-1.6	-1.9	-2.4	-0.6	-2.0
Medication: Paracetamol	0.8	1.3	2.9	1.2	-1.0	-1.1	-1.5	-1.7	-0.5	-0.5	-0.2	-1.7	-0.2	1.1	-0.8	-0.1	-1.0	-1.7	-1.0	-1.6	-1.3	-1.0
Basal metabolic rate	0.8	4.6	14.6	0.4	-2.1	-1.6	-1.1	-3.0	-1.2	-2.0	-2.3	-3.8	-2.9	-1.5	-2.5	-2.7	-1.9	-1.7	-2.0	-2.5	-0.7	-2.0
Arm fat-free mass (left)	0.8	4.1	9.7	0.2	-2.1	-1.7	-1.1	-2.8	-1.3	-2.2	-2.3	-3.1	-2.9	-0.9	-2.4	-2.8	-1.9	-1.6	-1.4	-2.2	-0.6	-1.9
Fractured/broken bones in last 5 years	0.8	1.0	2.2	-0.3	-1.2	-0.6	-0.1	-0.7	-1.5	-0.8	-1.4	-0.8	-1.3	1.5	-1.4	-1.2	-1.3	-0.7	-0.7	0.2	-0.7	-1.2
Vascular/heart problems diagnosed by doctor	0.8	2.2	26.7	-1.0	-0.4	-5.2	-0.5	-0.6	-0.7	-0.9	-0.6	-1.5	-0.9	-0.8	-0.6	-0.9	-0.7	0.0	-1.4	-2.0	-0.9	-0.4
Cholesterol lowering medication	0.8	1.1	6.5	-0.5	0.3	2.5	-0.2	0.1	0.1	-0.0	-0.1	1.4	0.5	1.9	0.1	0.4	0.4	0.9	2.1	1.7	0.5	0.5
Impedance of whole body	0.8	3.8	11.7	1.1	1.9	1.7	1.0	2.0	0.6	2.8	2.0	3.4	2.8	0.9	2.3	2.8	1.7	1.3	2.2	1.1	1.1	1.8
Hand grip strength (left)	0.7	1.7	6.8	1.2	-0.7	-2.6	-1.8	-1.8	1.1	-1.0	0.3	-0.9	-0.2	-1.2	-0.4	-0.0	-0.7	-1.7	-2.5	-1.6	-0.9	-0.7
Financial difficulties in last 2 years	0.7	0.9	3.8	2.0	-0.8	-0.1	0.2	-0.8	-0.1	0.4	0.3	1.0	-0.4	1.4	-0.7	-0.2	-0.7	-0.9	0.1	-1.8	-1.6	-0.8
Mouth/teeth dental problems	0.7	1.1	8.7	0.1	0.9	-0.7	2.9	-0.2	0.3	1.3	-1.1	0.5	-1.0	0.8	0.3	-1.0	0.8	1.0	1.0	1.0	0.6	0.9
Alcohol intake versus 10 years previously	0.7	1.0	3.5	1.2	1.1	0.9	1.3	-0.3	0.7	1.9	0.5	-0.4	0.4	1.0	1.0	0.4	1.2	1.2	1.6	-0.0	0.8	1.1
Father’s age at death	0.7	0.9	4.0	-1.1	-0.6	-2.0	0.2	0.1	-0.5	-0.8	-1.2	-0.8	-1.3	-0.6	-0.8	-1.4	-0.6	-0.5	-1.3	1.0	-0.3	-0.6
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	8.4	0.0	-1.6	-1.9	-1.0	-1.5	-0.7	-1.2	-1.5	-2.9	-1.9	-1.1	-1.8	-1.7	-1.6	-1.2	-1.7	-1.8	-1.0	-1.5
Pulse wave Arterial Stiffness index	0.7	0.8	9.1	0.5	-0.2	0.1	-0.2	0.5	-0.2	-1.1	0.1	0.8	-0.0	3.0	-0.4	0.1	-0.1	-0.1	1.1	0.9	-1.2	-0.2
Length of working week for main job	0.7	0.8	7.1	-0.3	-0.1	0.5	-0.8	0.3	0.0	-1.8	0.3	-2.7	0.4	-1.1	0.0	0.7	0.1	-0.2	-0.8	0.4	0.6	-0.2
Loud music exposure frequency	0.7	0.7	3.5	0.8	-0.5	-0.4	-1.4	-1.1	0.5	-1.0	-0.0	0.1	-0.2	1.9	-0.3	-0.3	-0.4	-0.4	-0.0	-1.3	-1.5	-0.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.0	0.7	0.2	1.4	-1.7	0.5	1.2	0.2	1.4	0.3	1.1	-1.7	0.5	1.4	0.3	-0.1	-0.3	0.1	0.8	0.3
Comparative body size at age 10	0.7	1.9	6.4	-0.3	-1.5	-0.5	-2.3	-2.5	-1.4	-1.1	-0.6	-0.6	-1.1	-0.0	-1.4	-1.1	-1.6	-1.9	-1.8	-0.4	-1.2	-1.4
Medication: Allopurinol	0.7	0.9	5.1	1.0	-0.8	-0.1	0.0	-1.3	-0.6	-1.4	-0.9	-0.6	-0.7	2.2	-1.0	-0.5	-0.6	-0.6	0.7	0.0	-1.4	-0.8
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.4	-1.8	0.3	-0.3	0.2	1.5	0.8	-0.8	0.1	-1.8	-0.4	-0.9	0.0	-0.3	0.4	0.3	-0.1	1.6	0.2	0.1
Illnesses of siblings: Diabetes	0.7	0.8	2.9	1.4	0.6	0.3	1.1	-0.1	1.4	1.3	0.4	0.1	0.2	-1.7	0.5	0.3	0.6	0.2	-0.1	-1.2	1.7	0.6
Smoking status: Previous	0.7	1.1	2.5	-0.8	-1.3	-1.3	-1.3	-0.8	-0.9	-0.6	-0.6	-0.8	-1.2	-0.2	-1.1	-1.1	-1.5	-1.6	-1.2	-0.7	-0.7	-1.3
Back pain experienced in last month	0.7	1.1	3.8	-0.1	-0.5	-0.9	1.4	0.3	-0.1	-0.1	-1.6	-2.0	-1.7	-0.8	-1.2	-1.7	-0.5	-0.1	-1.5	0.4	-0.6	-0.5
Osteoarthritis (self-reported)	0.7	0.9	2.2	-0.2	-1.2	-1.3	-1.2	-0.9	0.2	-1.2	-0.2	-1.4	-0.1	1.0	-0.7	-0.2	-1.0	-1.2	-0.4	-0.7	-1.5	-1.0
Supplements: Fish oil (including cod liver oil)	0.7	0.9	4.3	0.1	-0.8	-1.3	-0.5	-2.0	-0.8	-0.2	-0.8	0.2	-1.0	0.0	-0.7	-1.1	-1.0	-0.6	-0.7	-2.1	-0.1	-0.7
Respiratory disease	0.6	1.4	5.6	-1.4	-1.0	0.4	-1.1	0.6	-2.4	-1.7	-0.5	0.1	-0.7	1.4	-1.2	-0.6	-1.1	-0.6	-0.7	1.3	-1.9	-1.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.0	1.2	0.6	-0.4	0.3	-1.2	1.1	1.3	1.1	1.4	1.0	-1.2	1.0	0.7	0.6	0.2	-0.5	-0.8	0.4	0.7
Leg fat-free mass (left)	0.6	3.0	13.5	0.4	-1.6	-1.0	-0.8	-2.5	-0.9	-1.5	-1.6	-3.7	-2.1	-1.4	-1.8	-1.9	-1.3	-1.3	-1.7	-2.0	-0.4	-1.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.8	-0.4	0.9	1.0	0.9	1.0	0.4	0.5	0.3	0.5	0.2	0.6	0.8	0.3	1.0	1.0	1.4	0.9	1.3	1.0
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.5	1.1	-0.3	-1.0	-0.7	-1.2	0.9	0.6	1.1	0.9	0.6	-0.2	0.3	0.7	-0.4	-1.0	-0.9	-1.1	-0.1	-0.2
Qualifications: CSEs or equivalent	0.6	0.8	1.9	-0.0	-1.2	-0.3	-0.6	-0.6	-1.0	-1.4	-0.8	-1.2	-1.0	0.1	-1.2	-0.7	-1.1	-0.8	-0.5	-0.7	-1.2	-1.1
Sitting height	0.6	4.4	12.5	-1.1	-2.0	-3.1	0.8	-1.6	-1.9	-1.0	-3.0	-3.5	-2.9	-2.4	-2.5	-2.5	-2.0	-1.2	-1.7	-1.3	0.0	-2.0
Impedance of leg (left)	0.6	2.7	9.3	1.4	1.6	1.0	1.1	1.6	0.5	2.3	1.3	3.0	2.0	1.2	1.8	1.9	1.3	1.3	2.3	0.2	1.2	1.6
Leg predicted mass (left)	0.6	3.0	14.1	0.4	-1.5	-1.0	-0.8	-2.5	-0.8	-1.5	-1.6	-3.8	-2.1	-1.5	-1.8	-1.9	-1.3	-1.3	-1.7	-2.0	-0.3	-1.5
Number of incorrect matches in round	0.6	1.0	2.5	0.0	-1.2	0.1	-1.5	-1.0	-1.3	-1.4	-0.7	0.3	-0.6	1.4	-1.1	-0.6	-1.1	-1.1	0.6	-0.1	-1.6	-1.1
Forced vital capacity (FVC)	0.6	2.3	5.4	-0.3	-1.7	-1.9	-1.2	-1.6	-1.1	-1.5	-1.4	-2.3	-1.8	-0.2	-1.8	-1.6	-1.7	-1.4	-1.2	-1.2	-1.5	-1.7
Fluid intelligence score	0.6	1.2	6.8	-1.3	0.5	-2.6	1.3	0.8	0.9	-0.2	-0.6	-1.4	-0.6	-1.3	0.2	-0.6	0.7	1.0	0.2	1.2	1.5	0.7
Tense / ‘highly strung’	0.6	0.9	7.9	-0.5	-0.4	0.2	-1.4	-0.0	-0.4	-0.1	0.8	0.2	0.7	-2.8	0.0	0.9	-0.6	-1.0	-1.5	-0.0	1.0	-0.4
Medication: Paracetamol	0.6	1.0	3.8	2.0	-0.3	-0.7	-1.2	-1.3	0.0	0.5	0.4	-1.1	0.3	1.7	-0.1	0.4	-0.4	-1.2	-0.9	-1.6	-0.9	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.0	0.1	0.4	1.7	1.1	0.7	-0.4	0.2	0.7	0.9	0.6	1.7	0.5	0.6	0.7	0.7	1.2	1.4	0.0	0.5
High blood pressure (siblings)	0.6	0.9	2.4	-0.4	-1.2	1.0	-1.0	-0.9	-1.3	-0.4	-1.0	0.5	-1.0	1.6	-1.2	-1.0	-1.0	-0.7	0.2	-0.2	-1.0	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	5.6	-0.5	-0.5	-0.0	1.1	-0.2	-0.5	0.5	-0.6	0.4	-1.4	-2.4	-0.6	-1.5	-0.4	-0.4	0.1	0.3	1.3	-0.3
Supplements: Vitamin C	0.6	0.7	2.5	1.2	-0.3	1.0	-1.6	-0.9	-0.0	0.7	1.1	1.5	0.4	-0.0	0.2	0.2	-0.6	-0.8	-0.5	-1.5	-0.6	-0.4
Leg fat-free mass (right)	0.6	3.1	12.5	0.5	-1.6	-1.1	-0.7	-2.8	-0.8	-1.3	-1.7	-3.5	-2.3	-1.3	-1.9	-2.1	-1.4	-1.4	-1.7	-1.9	-0.4	-1.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.2	-0.2	0.4	1.0	-1.0	0.7	0.2	0.6	0.7	1.3	1.2	-1.2	0.7	1.5	0.3	-0.2	0.2	1.2	0.9	0.4
Loneliness, isolation	0.6	0.8	2.5	-0.2	-1.1	0.2	-1.6	-1.3	-0.4	-1.3	-0.5	-0.9	-0.3	-0.1	-0.9	-0.2	-0.9	-1.1	-1.0	-0.8	-1.4	-0.9
Friendships satisfaction	0.6	0.7	3.0	-0.5	0.8	-0.8	0.1	0.6	0.5	0.9	1.1	1.0	0.7	-0.1	0.8	0.9	0.7	1.0	1.7	0.8	1.0	0.8
Medication for cholesterol	0.6	0.9	5.0	0.4	0.5	-2.2	0.6	0.0	0.4	1.0	0.7	-1.0	0.2	-1.6	0.6	0.3	0.3	0.2	-1.3	-1.6	0.9	0.4
Medication: Aspirin	0.6	0.8	5.4	0.3	0.5	2.3	0.5	0.1	-0.4	1.0	0.8	0.5	0.9	0.2	0.6	0.9	0.7	0.4	1.7	0.2	0.9	0.4
Smoking status: Current	0.6	0.9	4.5	-1.4	0.4	-0.6	0.4	0.2	0.5	0.0	0.2	1.0	0.3	2.1	0.3	0.2	0.3	1.1	1.4	1.1	-1.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.4	0.7	-1.4	-0.8	-0.6	-1.5	-0.6	-1.1	-1.3	-0.8	-1.2	-0.5	-1.4	-1.2	-1.3	-1.1	-1.0	-2.1	0.1	-1.3
Leg predicted mass (right)	0.6	3.1	13.2	0.4	-1.6	-1.2	-0.7	-2.8	-0.7	-1.3	-1.7	-3.6	-2.3	-1.3	-1.9	-2.1	-1.3	-1.4	-1.7	-1.9	-0.5	-1.5
Guilty feelings	0.6	0.8	5.5	2.3	0.7	-0.1	0.8	-0.9	1.1	1.6	0.4	0.8	-0.0	-0.6	0.6	-0.3	0.4	0.4	0.3	-0.5	1.4	0.7
Hearing aid user	0.6	0.7	5.5	1.2	-0.2	1.2	-0.4	-0.4	-0.4	-0.8	-0.2	1.4	-0.2	2.4	-0.4	-0.4	-0.4	-0.1	0.7	-0.7	0.1	-0.3
Financial situation satisfaction	0.6	0.8	2.8	0.5	-0.8	-0.4	-0.6	-1.6	0.2	-0.7	-0.8	1.7	-1.2	0.4	-0.9	-1.1	-0.8	-0.7	0.3	-0.3	-1.2	-0.6
High cholesterol (Self-reported)	0.6	1.1	5.0	-0.5	0.6	1.7	1.9	0.5	0.3	0.8	-0.2	0.3	0.2	0.7	0.5	0.2	0.9	0.9	2.1	2.2	0.7	0.8
Medication: Lisinopril	0.6	0.8	3.4	0.4	0.7	1.2	0.6	-0.6	0.8	1.0	0.9	0.4	1.1	1.9	0.9	1.0	0.8	0.5	1.0	0.1	-0.5	0.7
Illnesses of father: High blood pressure	0.6	0.8	4.3	0.6	0.6	2.1	1.0	0.9	-0.1	0.8	1.0	1.2	1.0	0.9	0.7	0.8	0.7	0.5	0.8	0.2	0.8	0.6
Alcohol drinker status: Never	0.6	0.7	2.3	1.2	-0.8	0.2	-1.2	-1.0	-0.7	-0.5	-0.6	-1.5	0.0	0.8	-0.5	0.0	-0.7	-1.1	-1.1	-0.7	-0.9	-0.9
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.4	0.1	-0.7	1.0	0.5	-0.1	-1.4	0.1	-1.2	1.6	-1.1	-1.0	-1.0	-1.1	-0.8	-0.1	-0.3	-0.8	-0.1	-0.7
Diastolic blood pressure, automated reading	0.6	1.9	8.7	0.6	-1.5	-0.6	-1.6	-3.0	-0.7	-0.2	-0.1	0.4	-0.6	1.8	-1.2	-0.8	-1.5	-2.5	-0.7	-0.0	-2.1	-1.4
Supplements: Calcium	0.6	0.7	4.9	1.0	-0.4	0.5	-1.3	-0.9	-0.2	-0.5	0.5	-0.3	0.6	1.2	-0.0	0.6	-0.2	0.1	0.1	-2.2	-1.0	-0.3
Intelligence (Savage-Jansen 2018)	0.5	1.5	6.9	-2.1	0.5	-1.9	1.0	1.4	1.1	-0.3	-0.3	-2.6	-0.1	-2.2	0.2	-0.1	0.7	0.9	-0.2	0.7	1.7	0.5
Alzheimer’s Disease (including proxy)	0.5	0.7	2.8	1.3	1.0	-0.9	0.7	-0.0	1.7	1.1	0.5	0.4	0.2	-0.7	0.8	-0.1	0.8	0.5	-0.7	0.0	0.9	1.0
Reaction Time	0.5	0.9	4.6	2.1	0.0	-0.5	0.3	-1.7	-1.0	-0.4	-0.0	0.1	-0.5	1.0	-0.1	-0.2	0.1	-0.4	-1.4	-2.1	0.1	-0.0
Age at First Birth	0.5	0.8	2.8	-0.1	-0.9	-0.7	-0.1	-1.1	-0.0	-0.1	-0.8	-0.3	-1.6	-0.5	-1.1	-1.7	-0.8	-1.0	-1.6	-0.6	-0.4	-0.8
Mean Putamen Volume	0.5	0.6	1.2	-0.0	0.8	0.6	0.9	1.0	0.9	1.0	0.9	0.8	0.8	-0.8	0.8	0.5	0.9	1.1	0.0	-0.3	0.2	0.8
LDL Cholesterol	0.5	0.8	4.8	-1.8	-0.6	-1.5	-0.0	0.4	-0.3	-0.4	-0.5	-1.0	-0.6	-2.2	-0.7	-0.3	-0.6	-0.4	-0.9	0.3	-0.4	-0.6
Neuroticism	0.5	1.1	2.5	0.5	1.2	0.5	0.6	0.4	1.2	1.5	1.6	1.4	1.1	-0.3	1.4	1.0	0.9	1.2	0.6	0.2	1.4	1.3
Medication: Co-codamol	0.5	0.5	3.0	-0.6	0.3	-0.1	1.7	0.4	0.0	0.2	-0.2	-0.1	0.1	1.4	0.1	-0.0	0.4	1.1	1.2	-0.8	-1.0	0.4
Diabetes (mother)	0.5	0.6	2.0	1.4	-0.5	-0.4	-0.8	-1.1	-0.9	0.5	0.5	0.4	0.7	0.8	-0.0	0.7	-0.6	-1.1	-1.1	-1.0	-0.8	-0.5
Severe depression (siblings)	0.5	0.5	1.6	0.9	-0.6	-0.3	0.2	-1.2	-0.5	-0.0	-0.7	0.4	-0.8	0.9	-0.7	-0.9	-0.7	-0.9	-0.7	-1.3	-0.4	-0.6
Impedance of leg (right)	0.5	2.6	10.1	1.3	1.6	1.2	1.0	1.9	0.3	1.8	1.1	3.2	2.1	0.7	1.8	2.0	1.3	1.4	2.2	0.3	1.3	1.5
Serious illness, injury or assault to yourself	0.5	0.6	3.2	0.1	-0.9	-0.9	0.6	-0.2	-0.5	0.1	-0.4	-1.8	-0.4	-1.2	-0.5	-0.7	-0.6	-1.0	-0.9	-0.6	0.0	-0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.6	0.4	0.1	-0.9	-0.7	-0.7	-0.8	-0.6	1.3	1.2	0.9	1.2	0.4	0.6	-0.1	-0.2	1.1	0.4	0.6	0.2
Chronic bronchitis/emphysema (father)	0.5	0.5	1.9	-1.4	0.2	-0.4	1.3	1.2	0.7	0.4	-0.7	-0.9	-0.2	-0.0	-0.1	0.1	0.5	0.8	0.3	1.3	-0.3	0.2
Hair/balding pattern: Pattern 2	0.5	0.7	4.0	0.7	0.7	0.2	0.8	0.9	1.0	0.9	-0.5	-0.0	-0.5	-2.0	0.3	-0.5	0.5	0.5	-0.3	0.0	1.6	0.5
Heart attack	0.5	0.7	2.8	-0.2	-0.7	0.8	-1.7	-0.5	-0.6	0.1	0.6	0.2	1.0	-1.4	0.0	0.6	-0.7	-1.3	-0.0	0.2	1.2	-0.7
Neuroticism score	0.5	1.0	3.2	0.7	0.9	0.4	0.0	0.1	1.1	1.6	1.5	0.1	0.9	-1.8	1.2	0.8	0.7	0.7	-0.3	-0.2	1.7	1.1
Weight	0.5	2.3	10.1	0.4	-1.5	-0.5	-1.1	-2.2	-1.2	-1.3	-1.3	-3.2	-1.8	-1.2	-1.6	-1.7	-1.3	-1.5	-1.4	-1.6	-0.2	-1.4
Mouth/teeth dental problems: Dentures	0.5	0.8	3.1	-0.4	0.6	-0.1	-0.1	1.8	1.3	-0.0	1.1	0.4	1.0	-1.1	0.8	0.8	0.6	1.1	-0.3	-1.0	1.1	0.5
Breastfed as a baby	0.5	0.6	3.7	1.4	0.0	-0.7	-0.6	-0.4	0.8	1.0	0.7	-0.2	0.8	-0.3	0.4	0.6	-0.0	-0.5	-0.1	-0.7	1.9	0.1
Exposure to tobacco smoke outside home	0.5	0.6	3.0	-1.2	-0.7	0.2	-1.2	0.4	-0.5	-1.0	-0.8	-1.2	-0.1	-0.7	-0.5	0.1	-0.6	-0.7	-0.0	1.7	-0.2	-0.7
Age at first live birth	0.5	0.9	5.8	0.5	0.2	-1.1	1.3	-0.6	1.1	1.2	-0.2	0.0	-0.8	-2.4	-0.0	-1.1	0.1	0.2	-1.0	-1.1	1.3	0.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.5	1.0	0.0	1.6	-0.9	0.2	0.8	0.5	1.1	0.1	1.2	0.5	0.5	1.3	0.3	-0.5	0.0	0.3	0.1	0.1
Osteoporosis (self-reported)	0.5	0.6	2.2	0.1	0.9	0.7	0.3	1.2	0.9	0.6	0.1	1.0	0.2	0.6	0.5	0.3	0.7	1.4	1.5	0.7	0.6	0.8
Number of self-reported non-cancer illnesses	0.5	0.9	2.6	-0.3	-1.0	0.7	-0.6	0.0	-1.6	-0.8	-1.3	0.8	-1.2	1.6	-1.2	-1.2	-0.9	-0.6	0.2	0.5	-1.1	-0.8
Miserableness	0.5	0.9	3.1	-0.1	1.1	0.4	0.5	0.5	0.9	0.9	1.3	-1.8	0.7	-0.9	1.3	0.7	1.1	1.3	0.0	-0.5	0.5	1.2
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.9	-0.3	-0.8	0.8	-1.7	-0.4	-0.7	0.1	0.6	0.2	0.9	-1.1	-0.1	0.5	-0.7	-1.4	-0.2	0.2	1.0	-0.8
Schizophrenia (2018)	0.4	0.8	3.4	1.8	0.0	1.3	1.4	-1.4	-0.3	-0.3	-0.6	1.2	-0.3	0.8	-0.1	-0.4	0.2	-0.4	-0.5	-0.5	-1.3	-0.2
Schizophrenia vs Biploar Disorder	0.4	0.5	3.9	-1.0	0.4	-0.2	0.6	0.5	-0.2	0.2	-0.2	0.3	0.4	2.0	0.3	0.5	0.4	0.6	0.5	1.3	-0.7	0.5
HbA1C	0.4	0.5	1.9	-1.0	-0.8	-0.2	0.9	0.2	-0.2	-0.5	-1.0	-1.4	-0.9	-0.4	-0.9	-0.5	-0.4	-0.1	0.0	-0.1	-0.9	-0.5
Neuroticism (2016)	0.4	0.5	2.3	-1.5	-0.4	-1.0	-0.6	-0.6	-0.6	-0.8	-0.8	-0.7	-0.6	-0.2	-0.6	-0.6	-0.7	0.2	-0.5	-0.1	-1.3	-0.5
Blood Red Count	0.4	3.6	7.5	-0.1	-2.7	-0.6	-1.4	-1.9	-2.4	-2.7	-1.6	-0.5	-1.6	1.1	-2.6	-1.6	-2.5	-2.4	-1.1	-2.0	-1.8	-2.6
Systolic Blood Pressure	0.4	2.0	13.4	-1.9	-0.5	3.7	-0.4	1.1	-0.8	0.1	0.6	2.6	1.0	1.4	-0.3	0.9	-0.4	-0.4	-0.4	2.0	-1.6	-0.6
Chronotype (morning person)	0.4	1.0	3.8	1.6	0.9	-0.4	-0.2	0.7	0.8	-0.0	1.2	-1.5	0.8	-1.7	1.1	0.5	0.9	0.3	-0.3	0.0	1.9	1.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.4	0.4	-0.5	-1.0	-1.1	-0.9	-0.6	-0.5	0.4	-0.1	0.1	1.3	-0.1	-0.3	-0.4	-0.3	1.5	-0.9	-0.1	-0.4
Systolic blood pressure, automated reading	0.4	1.3	5.9	-2.4	-1.1	0.8	-0.6	0.0	-1.2	-0.2	0.1	1.6	-0.3	0.9	-1.1	-0.6	-1.1	-1.2	-0.3	2.0	-1.4	-1.1
Pack years adult smoking proportion	0.4	0.6	3.0	-1.7	-0.3	1.4	-1.2	0.8	0.1	-0.7	0.2	0.6	1.1	-0.2	0.0	1.3	-0.2	0.3	0.0	0.4	-0.9	-0.2
Townsend deprivation index at recruitment	0.4	0.6	3.3	0.8	-0.8	1.1	-0.7	-0.9	-0.8	-0.2	-0.9	-0.2	-0.5	0.4	-0.9	-0.7	-0.7	-0.5	0.0	-1.8	-0.3	-0.7
Average weekly fortified wine intake	0.4	0.5	3.0	0.5	0.1	-0.3	0.4	-0.4	-0.6	1.2	0.9	-0.3	0.3	-1.7	0.2	0.2	0.0	-0.5	-0.4	-0.8	1.1	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.2	1.0	0.2	0.1	-0.3	-1.4	0.4	0.2	0.8	1.5	0.6	-1.5	0.5	0.8	0.1	0.2	0.2	-1.1	-0.5	0.3
Relative age voice broke	0.4	0.7	3.0	-0.5	0.2	0.6	-0.7	1.1	-0.6	-0.1	0.9	1.6	1.6	-0.2	0.7	1.7	0.1	0.2	-0.5	-0.2	0.0	0.2
Supplements: Glucosamine	0.4	0.5	2.0	1.3	0.4	0.4	1.1	0.3	-0.3	1.0	0.4	0.7	0.0	-0.1	0.3	-0.1	0.4	0.5	0.4	-1.3	1.4	0.5
Allergy	0.4	0.9	3.9	0.4	0.1	-0.7	-1.1	0.2	0.8	-0.7	1.1	-1.6	1.2	-1.3	0.8	1.1	0.3	0.0	-0.5	-2.0	0.9	0.3
Worrier / anxious feelings	0.4	0.8	2.8	1.0	0.9	0.9	-0.2	0.5	0.6	0.9	0.8	1.6	0.7	-0.9	1.0	0.6	0.6	0.3	1.0	0.9	1.7	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.9	1.4	0.5	0.3	0.7	-0.6	1.1	1.4	0.9	-0.6	0.5	-0.4	0.6	0.5	0.4	0.5	1.1	-0.9	0.8	0.7
Happiness	0.4	0.5	1.8	0.1	0.7	-0.1	0.8	-0.1	1.3	1.4	0.8	0.2	0.4	-0.4	0.7	0.3	0.7	0.7	0.8	0.4	0.6	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.3	-0.3	0.7	0.5	1.4	0.2	0.3	0.8	0.2	-1.5	-0.1	0.7	0.3	-0.2	0.6	1.0	0.9	0.3	0.2	0.6
Asthma	0.4	0.8	5.7	-0.5	0.7	1.3	0.2	1.4	-0.7	-0.1	0.6	0.6	0.4	1.5	0.4	0.7	0.5	0.8	0.8	2.4	-0.2	0.6
Standing height	0.4	3.7	10.2	1.6	-1.7	-2.3	0.4	-3.2	-1.8	-0.5	-2.4	-1.4	-2.5	-1.3	-2.3	-2.4	-1.8	-1.3	-1.1	-3.0	-0.2	-1.8
Pulse wave reflection index	0.4	0.4	3.2	-0.3	0.5	-0.7	0.1	0.6	-0.3	-0.8	0.4	-0.6	0.3	1.8	0.3	0.4	0.5	0.8	0.8	0.4	-0.7	0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	5.2	-0.0	-0.4	-2.3	-1.2	-0.2	-0.7	-0.2	-0.7	0.0	-1.1	-0.6	-0.6	-1.1	-0.8	-0.3	-1.2	-0.5	-0.5	-0.4
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.7	1.2	0.7	-0.7	1.3	0.2	0.5	0.7	-0.1	-0.3	-0.3	1.0	0.4	-0.4	0.7	0.8	-0.1	-1.0	-0.1	0.7
Worry too long after embarrassment	0.4	0.7	3.1	-0.0	0.7	-0.1	1.8	0.3	0.6	1.0	-0.5	1.4	-0.5	-0.5	0.2	-0.3	0.7	1.6	0.4	-0.4	0.7	0.9
Wheeze or whistling in the chest in last year	0.4	0.6	3.3	0.9	0.3	1.6	-0.5	0.2	0.3	0.0	1.1	0.6	0.7	1.8	0.5	0.6	0.3	-0.2	0.9	1.0	-0.1	0.3
Medication for pain relief, constipation, heartburn	0.4	0.6	2.8	-1.7	-0.2	-0.7	0.7	-0.3	-0.5	-0.9	-0.8	0.5	-0.8	-1.3	-0.4	-1.0	-0.3	0.3	0.5	1.2	0.5	-0.2
Mean time to correctly identify matches	0.4	0.8	4.8	2.0	0.9	0.2	0.9	-0.4	-0.2	0.6	0.6	0.6	0.1	2.2	0.8	0.2	0.9	0.5	-0.2	-0.8	0.8	0.9
Heart disease (mother)	0.4	0.5	2.8	0.9	0.4	1.7	0.2	0.4	0.1	-0.1	-0.0	1.2	0.3	1.4	0.3	0.4	0.4	0.6	0.5	0.3	-0.6	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.2	0.6	0.6	1.0	0.7	0.1	0.4	0.6	0.6	0.3	0.6	-1.1	0.6	0.4	0.4	0.5	0.5	-0.9	1.1	0.5
Comparative height size at age 10	0.4	2.2	6.5	0.1	-1.5	-1.6	-0.8	-2.5	-1.6	-1.2	-1.9	-1.3	-1.9	-0.1	-1.8	-1.9	-1.6	-1.1	-0.7	-1.6	-1.4	-1.5
Suffer from ‘nerves’	0.4	0.7	1.8	-0.9	-1.0	-0.9	-1.3	0.1	-0.4	0.2	-0.2	0.0	-0.4	-1.3	-0.8	-0.6	-1.2	-1.1	-1.4	-0.1	-0.4	-1.0
Leg pain on walking	0.4	0.5	2.4	1.0	-0.4	-0.8	0.3	-0.7	-0.1	-0.3	-0.3	-1.5	-0.6	1.6	-0.5	-0.7	-0.6	-0.2	0.1	-1.3	0.0	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.0	-0.4	-0.0	-0.6	-1.7	-0.1	-0.4	-0.8	0.7	-0.4	0.9	-0.7	0.4	0.9	-0.2	-0.3	-1.2	-0.1	0.5	-0.0
Medication: Aspirin	0.4	0.6	4.9	-0.2	-0.0	2.2	0.2	-0.0	-0.7	0.4	0.5	0.5	0.7	1.1	0.2	0.7	0.2	0.0	1.5	0.2	-0.3	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.5	1.2	-0.1	0.1	0.3	-1.1	-0.0	-0.7	-1.1	-1.2	-0.5	-1.9	-0.6	-0.5	-0.1	0.5	-0.5	-1.9	1.1	-0.2
Long-standing illness, disability or infirmity	0.4	0.5	1.2	-0.7	-1.0	0.5	-0.8	-0.6	-0.7	-0.8	-1.1	-0.8	-0.6	0.1	-1.0	-0.7	-0.9	-0.7	-0.4	-0.2	0.0	-1.0
Ever had bowel cancer screening	0.4	0.4	3.5	-0.5	0.1	0.2	-0.0	1.0	-0.2	-0.3	0.1	0.7	0.0	-1.4	0.2	0.1	0.1	0.5	0.1	0.4	1.9	0.3
Diabetes diagnosed by doctor	0.4	0.7	2.3	0.6	0.7	1.5	-0.2	0.5	1.3	1.1	0.8	-0.7	1.2	0.0	1.0	1.1	0.8	0.3	0.1	0.3	0.9	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	3.9	-0.9	-0.8	-0.2	-0.1	-0.5	-0.6	-0.4	-0.6	-2.0	-0.5	-0.3	-0.7	-0.3	-0.5	-0.5	-0.9	-0.4	0.0	-0.7
Mineral and other dietary supplements	0.4	0.5	2.9	-1.4	-0.3	-0.2	-0.4	1.1	-0.1	-1.0	-0.2	-0.8	-0.1	-0.7	-0.4	-0.1	-0.1	-0.3	-0.7	1.7	-0.6	-0.4
Medication: Gliclazide	0.4	0.4	2.2	-1.2	-0.2	0.4	-0.3	1.0	-0.3	0.1	0.1	-1.2	0.1	-1.5	-0.0	0.1	-0.3	-0.4	-0.4	1.1	0.3	-0.3
Wears glasses or contact lenses	0.4	0.4	3.7	0.8	0.1	0.7	0.2	0.9	-0.1	0.5	-0.2	0.9	0.4	-0.6	0.3	0.4	0.0	-0.3	0.0	-0.5	1.9	0.2
Mother’s age at death	0.4	0.5	2.8	0.3	0.9	0.4	0.4	1.7	0.5	-0.2	0.2	0.2	0.1	-0.9	0.7	-0.1	0.9	0.9	-0.7	0.5	0.8	0.8
Ever depressed for a whole week	0.4	0.5	2.2	-1.1	0.0	1.0	0.2	0.3	0.4	-0.8	0.2	-1.2	-0.2	1.5	-0.2	-0.2	0.1	0.7	0.4	0.7	-0.9	0.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.8	0.4	-0.4	-0.7	-1.0	0.2	-0.0	-0.8	0.3	-1.7	0.2	1.4	-0.0	0.1	-0.3	-0.2	-1.1	-0.7	-0.6	-0.2
Basal cell carcinoma (self-reported)	0.4	0.5	2.8	0.3	0.6	0.1	-0.3	1.7	0.9	0.3	1.0	0.2	0.9	-0.6	0.8	0.8	0.8	0.5	-0.2	-0.1	0.6	0.7
Alcohol drinker status: Previous	0.4	0.5	2.4	0.5	0.1	0.9	-0.8	-0.9	-0.0	0.1	-0.8	1.1	-0.5	-1.6	-0.1	-0.9	0.1	0.4	0.9	-0.3	0.6	0.2
Pack years of smoking	0.4	0.6	3.4	-1.9	-0.3	1.3	-1.1	1.1	-0.0	-0.6	0.1	0.3	1.0	-0.9	0.0	1.1	-0.2	0.3	-0.1	0.4	-0.5	-0.2
Depressed Affect (Nagel 2018)	0.3	0.6	2.9	-0.6	0.1	0.7	-1.1	-0.3	0.5	0.3	1.7	0.3	1.3	0.6	0.7	1.5	0.1	-0.0	0.1	0.3	-0.4	0.2
Worry (Nagel 2018)	0.3	0.7	3.1	-0.2	-0.6	-0.0	-1.8	-0.6	-1.0	-0.2	0.7	1.5	0.5	-0.6	-0.2	0.7	-1.1	-1.1	-0.8	-0.3	0.1	-0.7
Allergy or Eczema	0.3	0.7	2.6	0.3	0.3	1.2	1.1	0.1	0.2	1.6	-0.6	1.6	-0.4	1.1	-0.2	-0.5	0.2	0.6	1.3	0.9	-0.3	0.2
Lung FEV1/FVC ratio	0.3	1.3	4.8	-0.8	-0.9	-1.3	0.2	-0.6	0.1	-0.3	-1.5	-2.1	-1.3	-2.2	-1.2	-1.3	-0.9	-0.5	-1.7	-1.1	0.4	-0.9
Lung FVC	0.3	1.4	2.9	-0.2	-1.2	-1.7	-1.7	-1.2	0.3	-1.2	-1.0	-1.6	-1.4	-0.1	-1.1	-1.3	-1.3	-1.4	-1.1	-0.7	-1.2	-1.0
Number of treatments/medications taken	0.3	0.6	3.6	0.3	-0.5	1.6	-0.2	0.3	-0.4	-0.5	0.2	-0.2	0.1	1.9	-0.4	-0.2	-0.2	0.2	0.5	-1.6	-0.9	-0.3
Relative age of first facial hair	0.3	0.6	2.1	0.6	0.5	0.3	-0.5	0.8	-0.2	0.3	1.0	1.4	1.5	0.8	0.8	1.3	0.4	0.6	-0.1	-0.2	0.3	0.6
Ever had hysterectomy (womb removed)	0.3	0.3	2.5	-0.6	0.3	0.6	-0.4	-0.0	-0.1	0.5	0.4	1.6	0.2	1.0	0.2	0.3	-0.1	0.1	-0.0	0.3	-0.5	0.1
Medication: Metformin	0.3	0.5	1.6	0.4	0.1	0.9	-0.5	0.3	0.7	0.4	0.8	-0.7	1.2	-0.9	0.6	1.2	0.2	-0.6	-0.7	0.3	0.7	0.0
Trunk fat percentage	0.3	1.3	4.0	1.3	1.1	2.0	0.1	0.5	0.2	1.6	1.6	-0.5	1.3	-0.0	1.4	1.4	1.3	0.5	1.1	0.1	1.5	1.2
Hand grip strength (right)	0.3	0.8	4.4	0.3	-0.1	-2.1	-0.6	-1.2	1.1	-0.8	0.3	-0.8	-0.2	-1.7	-0.1	-0.1	-0.2	-0.6	-1.7	-0.4	-0.4	-0.2
Stomach or abdominal pain in last month	0.3	0.4	1.6	1.3	-0.2	-1.2	-0.1	-0.7	0.1	0.5	0.7	-0.3	0.5	-0.3	0.0	0.3	-0.1	-0.7	-1.2	-1.2	0.1	-0.1
High blood pressure (mother)	0.3	0.4	2.1	0.6	0.0	1.5	-0.2	-0.2	0.4	-0.2	-0.0	-1.2	0.2	1.1	-0.2	0.5	0.0	0.2	0.8	0.4	-0.6	-0.1
Alcohol usually taken with meals	0.3	0.5	2.2	0.6	-0.6	0.1	0.3	-0.7	-0.9	-0.4	-1.0	0.9	-0.7	-1.5	-0.7	-0.6	-0.5	-0.8	-0.8	-0.5	-0.5	-0.6
Qualifications: None of the above	0.3	0.6	4.5	0.3	0.1	0.2	-0.4	-0.0	-0.2	0.2	0.9	1.9	0.7	2.1	0.4	0.8	0.0	0.1	0.9	-0.5	-0.9	0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	-1.1	-0.4	-0.2	0.4	-0.0	-0.7	0.8	-0.2	0.4	-0.1	0.7	-0.5	0.0	-0.3	-0.5	-0.5	0.5	-1.5	-0.4
Medication: Ramipril	0.3	0.4	1.8	-1.3	-0.5	0.9	0.8	0.7	-0.1	-0.2	-0.8	-0.9	-0.7	0.4	-0.7	-1.2	-0.2	0.3	-0.1	0.5	-0.3	-0.3
Hip circumference	0.3	1.1	6.6	0.4	-0.6	0.5	-1.1	-1.4	-0.7	-0.2	-0.4	-2.6	-1.1	-1.7	-0.7	-1.2	-0.5	-1.0	-1.2	-0.6	0.5	-0.6
Number of live births	0.3	0.5	1.3	0.7	0.8	-0.9	0.8	0.8	0.4	0.9	1.1	0.2	0.6	0.6	0.8	0.6	0.7	0.7	0.4	-0.4	0.3	0.8
Pulse rate	0.3	0.4	2.5	0.6	0.2	0.6	-0.8	-0.2	1.6	0.7	0.5	0.2	0.4	0.4	0.5	0.4	0.2	-0.1	0.6	1.4	0.2	0.5
Medication: Amlodipine	0.3	0.4	2.5	0.1	0.3	1.6	-0.4	0.3	0.6	-0.9	0.4	0.7	0.7	0.2	0.3	0.9	0.4	0.3	0.8	0.7	-0.0	0.3
Birth weight	0.3	0.6	2.0	0.5	0.8	-0.1	0.8	-0.1	-0.5	0.9	0.5	1.1	0.1	0.2	0.5	0.1	0.5	1.2	1.4	-0.7	1.1	0.8
Qualifications: College or University degree	0.3	1.0	4.5	0.3	0.8	1.9	1.2	0.1	0.9	0.3	-0.5	-1.2	0.1	-1.2	0.4	-0.1	1.0	1.2	0.3	0.9	2.1	0.7
Medication: Omeprazole	0.3	0.4	2.7	0.6	-0.2	-1.0	-0.3	0.0	0.3	-0.4	0.3	-1.6	0.1	1.1	0.1	0.1	-0.2	0.2	-0.3	-1.1	-0.0	0.0
Pulse rate, automated reading	0.3	1.1	6.1	-0.5	0.8	1.3	0.1	0.7	1.4	0.5	-0.2	1.4	0.3	1.1	0.7	0.1	0.8	1.3	1.6	2.5	-0.0	1.1
Overall health rating	0.3	0.5	1.7	-0.2	-1.0	-0.6	-1.3	-0.7	-0.2	-1.0	-0.3	-1.1	-0.4	0.4	-0.8	-0.6	-1.0	-1.0	-0.5	0.1	-0.3	-0.8
Family relationship satisfaction	0.3	0.3	2.0	-0.1	0.7	0.5	0.6	0.0	0.9	0.0	-0.1	0.5	-0.1	0.6	0.2	-0.2	0.6	1.4	1.0	0.1	0.3	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.7	0.1	0.6	0.3	0.6	0.2	0.2	-0.2	-0.2	-0.4	-0.2	-0.1	0.4	-0.1	0.5	1.1	0.6	0.6	1.3	0.7
Asthma (self-reported)	0.3	0.7	5.1	-0.6	0.4	1.0	0.1	1.1	-1.0	-0.1	0.5	0.8	0.3	1.4	0.2	0.6	0.2	0.4	0.6	2.3	-0.3	0.3
Irritability	0.3	0.5	1.6	-0.5	0.4	-0.4	-0.1	-0.0	0.4	0.9	1.2	-1.0	0.7	-1.3	0.8	0.8	0.2	0.0	0.2	0.7	1.0	0.5
Risk taking	0.3	0.4	1.5	-0.2	-0.1	0.7	0.7	0.8	-0.9	-0.4	-0.5	-0.8	-0.0	1.2	-0.3	0.1	-0.2	0.3	1.0	-0.5	-0.7	-0.3
Age started oral contraceptive pill	0.3	0.4	1.6	-0.2	0.1	0.4	0.9	0.8	-0.1	0.3	-0.7	0.3	-1.0	-0.4	-0.2	-1.3	0.3	0.8	-0.6	-0.2	0.5	0.3
Ovarian Cancer	0.2	0.3	1.0	0.3	0.4	-0.1	0.8	-0.8	0.4	-0.0	-0.4	-0.2	-0.6	-1.0	0.0	-0.9	0.4	0.6	0.4	0.5	0.3	0.4
Crohns Disease (2012)	0.2	0.4	2.0	-0.7	-0.7	-0.0	-0.1	-0.7	-1.4	-0.1	-0.5	-0.0	-0.3	-0.8	-0.6	-0.3	-0.9	-0.5	-0.4	-0.3	-0.5	-0.7
Primary Biliary Cirrhosis	0.2	0.3	1.5	0.3	0.0	0.6	1.2	-0.3	-0.1	0.2	-0.9	-0.8	-0.9	-0.8	-0.4	-0.8	0.0	0.1	-0.2	0.1	-0.0	-0.0
Ulcerative Colitis	0.2	0.3	1.3	0.3	-0.5	-0.1	1.2	-0.3	-0.5	0.4	-0.6	-0.2	-0.7	-1.0	-0.5	-0.8	-0.2	-0.3	-0.6	-0.2	0.7	-0.2
Blood Eosinophil Count	0.2	1.9	4.7	-1.1	-1.2	-2.2	0.1	0.2	-1.2	-1.2	-1.9	-1.9	-1.8	0.3	-1.7	-1.4	-1.1	-0.6	-1.7	-0.8	-1.6	-1.3
Blood White Count	0.2	1.2	3.4	-0.6	-1.6	0.4	-0.8	-1.6	-0.6	-1.1	-1.0	-0.9	-0.5	-0.1	-1.4	-0.5	-1.7	-1.8	-0.7	-0.2	-1.2	-1.8
Smoking Status	0.2	0.4	2.5	-0.7	-0.2	-1.3	0.1	-0.3	0.1	0.0	-0.4	0.2	-0.6	1.6	-0.2	-0.4	-0.4	0.1	0.2	0.0	-1.6	-0.2
Sensitivity / hurt feelings	0.2	0.4	1.8	0.6	0.5	0.9	0.3	-0.2	-0.3	1.1	0.5	1.3	-0.1	-0.0	0.5	-0.2	0.3	0.5	0.3	0.2	1.3	0.7
Maternal smoking around birth	0.2	0.3	1.6	0.5	0.4	0.1	0.6	-0.4	0.2	0.8	0.3	0.5	0.1	-0.7	0.2	0.1	0.1	0.2	1.3	-1.2	0.8	0.3
Taking other prescription medications	0.2	0.3	1.2	-0.2	-0.4	1.0	-0.9	0.2	-0.5	-0.3	0.2	0.4	0.1	1.1	-0.2	-0.1	-0.3	-0.0	0.1	0.1	-1.1	-0.3
Age when periods started (menarche)	0.2	0.6	2.3	1.0	-0.7	-1.5	0.0	-1.1	-0.3	0.3	-0.0	1.1	-0.1	-0.5	-0.4	-0.3	-0.9	-1.5	-0.5	-0.4	-0.0	-0.8
Body mass index (BMI)	0.2	0.8	6.8	-0.2	-0.8	0.6	-1.4	-0.9	-0.4	-1.1	-0.1	-2.6	-0.6	-0.5	-0.6	-0.5	-0.5	-1.0	-1.0	-0.4	-0.2	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.1	0.3	0.4	-0.5	1.4	-0.2	0.6	-0.1	-0.1	-0.8	-0.2	0.3	0.2	-0.3	0.5	0.5	1.4	0.5	0.1	0.4
Pain all over the body in last month	0.2	0.2	1.7	0.3	-0.3	-0.2	0.0	-0.1	0.3	-0.1	0.4	1.3	0.1	0.2	-0.1	0.2	-0.2	-0.4	-0.2	-0.5	-0.6	-0.3
Diabetes (self-reported)	0.2	0.3	1.2	-0.4	0.1	1.0	-0.5	0.2	0.6	0.3	0.3	-1.1	0.7	-0.5	0.4	0.7	0.2	-0.1	-0.6	0.3	-0.1	-0.0
Illnesses of siblings	0.2	0.3	0.8	0.3	0.8	-0.4	-0.5	0.3	0.3	-0.3	0.9	-0.1	0.9	-0.8	0.8	0.6	0.6	0.4	-0.3	0.1	0.6	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	3.1	0.9	0.6	1.8	0.4	-0.0	-0.2	1.4	0.3	-0.1	0.3	-1.0	0.5	0.3	0.7	0.3	-0.0	0.5	0.6	0.6
Lung cancer (father)	0.2	0.3	1.1	-0.1	0.1	-0.2	0.4	-0.1	1.0	0.8	-0.4	-0.5	-0.2	1.0	-0.0	-0.5	0.2	0.6	0.4	-0.6	-0.6	0.2
Arm fat mass (right)	0.2	0.8	4.5	0.9	-0.8	0.5	-1.1	-1.5	-0.6	-0.4	-0.2	-2.1	-0.6	-0.3	-0.6	-0.5	-0.5	-1.1	-0.7	-1.1	-0.3	-0.6
Birth weight of first child	0.2	0.4	2.2	0.8	0.1	-0.2	0.5	-0.7	-0.3	0.5	-0.8	1.5	-0.7	-0.4	-0.1	-0.9	-0.1	0.5	0.5	-1.1	0.8	0.1
Peak expiratory flow (PEF)	0.2	0.6	2.3	-0.6	-0.5	-0.7	-0.2	-0.3	-0.1	-0.7	-1.0	-0.9	-1.4	-0.8	-0.8	-1.5	-0.6	-0.0	-0.4	-0.5	-0.7	-0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.8	0.3	-0.2	-0.2	-0.8	-1.1	-0.0	-0.4	0.3	-1.7	-0.0	-1.0	0.0	0.1	-0.1	-0.4	-0.1	-0.6	-0.1	-0.1
Headache pain in last month	0.2	0.3	1.1	1.1	0.5	-0.1	0.8	-0.1	0.6	0.5	0.8	0.5	0.8	-0.5	0.6	0.6	0.6	-0.1	0.4	-0.5	0.6	0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.1	0.1	0.7	0.3	-0.5	0.1	0.7	0.8	1.1	0.7	0.6	0.4	0.7	0.5	0.6	0.2	0.6	0.5	0.3	0.6
Body fat percentage	0.2	0.9	3.8	1.0	0.7	2.0	-0.3	0.5	-0.1	1.1	1.3	-0.7	1.1	0.0	1.1	1.1	0.9	0.2	1.0	0.1	1.3	0.9
Number of full brothers	0.2	0.3	0.8	-0.5	0.1	0.7	-0.6	0.9	-0.5	-0.8	0.8	0.2	0.4	-0.4	0.2	0.5	0.1	0.1	0.1	0.6	-0.4	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.0	-1.0	-0.7	-0.9	0.3	0.3	-0.4	-0.7	-0.1	0.2	-0.5	-0.5	-0.6	-0.6	-0.6	-0.4	0.3	-0.4	0.3	-0.5
Migraine (self-reported)	0.2	0.3	1.6	1.1	-0.1	0.3	0.1	-1.2	0.4	0.1	-0.5	0.2	-0.2	1.0	-0.2	-0.2	0.1	-0.2	-0.7	-0.4	-0.7	-0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.6	0.8	-0.2	0.4	0.7	-0.5	-0.5	-0.1	-0.4	0.3	-0.6	0.7	-0.4	-0.5	-0.2	0.0	-0.2	-0.0	-0.5	-0.2
Alcohol intake frequency.	0.2	0.5	2.8	1.2	-0.3	1.7	-0.4	-1.0	-0.4	0.8	-0.7	-0.4	-0.3	-0.7	-0.3	-0.3	-0.1	-0.1	-0.3	-1.0	0.4	-0.2
Knee pain experienced in last month	0.2	0.2	1.0	0.4	-0.1	0.6	-1.0	-0.3	0.5	-0.5	0.5	-0.7	0.0	-0.9	-0.0	-0.0	-0.2	-0.5	0.1	0.3	0.3	-0.0
Illnesses of father: None of the above (group 1)	0.2	0.3	1.4	0.2	0.1	-0.4	-1.2	-0.1	0.8	-0.4	0.6	0.1	0.7	0.8	0.5	0.6	0.1	0.1	0.2	-0.8	-0.6	0.2
Unable to work because of sickness or disability	0.2	0.2	0.6	0.1	0.4	-0.1	-0.3	0.4	0.8	0.4	0.7	-0.6	0.7	-0.3	0.7	0.3	0.6	0.4	-0.2	0.4	0.5	0.7
Myopia	0.2	0.2	0.7	0.7	0.0	0.3	-0.3	0.4	0.5	0.7	-0.6	-0.9	-0.4	-0.6	-0.2	-0.7	0.0	-0.2	-0.6	-0.2	0.6	-0.1
Neuroticism (Nagel 2018)	0.1	0.3	1.5	-0.5	-0.1	0.1	-0.9	-0.5	-0.5	0.4	1.1	1.2	0.7	0.5	0.3	0.9	-0.4	-0.2	-0.1	-0.0	0.1	-0.1
Crohns Disease (2017)	0.1	0.2	1.5	-0.7	-0.3	0.3	0.2	-0.6	-1.2	-0.6	-0.3	0.1	0.0	-0.5	-0.2	0.1	-0.5	0.0	0.3	0.1	0.4	-0.3
Irritable Bowel Disease (IBD)	0.1	0.2	1.3	-0.6	-0.3	0.1	0.5	-0.8	-0.9	-0.2	-0.4	-0.0	-0.2	-0.5	-0.3	-0.3	-0.4	-0.1	0.3	-0.0	1.1	-0.2
Ulcerative Colitis (UC)	0.1	0.2	2.4	-0.4	-0.1	0.3	0.4	-0.4	-0.3	0.5	-0.1	-0.4	0.0	-0.6	-0.1	-0.2	-0.0	0.0	0.6	0.1	1.6	0.1
Heel T-Score	0.1	1.2	7.1	0.4	-0.6	-0.5	1.2	-0.1	-1.2	-0.7	-2.1	-2.7	-1.5	-0.7	-0.9	-1.5	-0.3	-0.2	-0.2	0.1	0.2	-0.6
BMI	0.1	0.7	12.0	-0.5	-0.1	0.8	-0.1	-0.2	0.3	-0.8	0.1	-3.5	-0.3	-0.2	-0.1	-0.4	0.2	-0.1	-0.2	-0.1	-0.2	-0.1
Height	0.1	2.6	8.5	2.4	-1.1	-2.3	0.8	-2.3	-1.9	0.1	-1.5	-1.7	-1.8	-1.0	-1.4	-1.9	-1.3	-0.9	-0.6	-2.9	0.5	-1.1
Hypothyroidism (self reported)	0.1	0.2	1.0	0.1	0.4	0.5	-0.2	-0.3	-0.0	0.5	0.4	1.0	0.1	0.0	0.3	-0.0	0.2	0.1	1.0	0.5	0.4	0.3
Tanning	0.1	0.8	3.5	-0.1	1.1	-1.9	0.8	0.5	0.9	-0.4	-0.2	-1.1	-0.3	-0.4	0.6	-0.3	1.0	1.5	0.5	-0.4	1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.4	0.4	0.0	-0.5	0.9	-0.3	0.3	-0.2	-0.6	-0.4	-0.4	0.4	-0.2	-0.6	-0.0	0.0	1.2	0.2	-0.1	-0.1
Trunk fat mass	0.1	0.5	2.5	1.2	0.3	1.3	-0.2	-0.4	-0.2	0.8	0.6	-1.6	0.2	-0.6	0.5	0.3	0.5	-0.1	0.3	-0.6	1.2	0.4
Waist circumference	0.1	0.3	2.3	0.3	-0.2	1.5	-0.6	-0.2	-0.4	-0.0	0.4	-0.8	0.1	-0.7	0.0	0.1	-0.0	-0.5	0.1	0.2	0.8	-0.1
Arm fat percentage (right)	0.1	0.6	3.0	0.9	0.3	1.7	-0.9	-0.3	0.0	0.7	1.1	-0.8	0.9	0.2	0.8	1.0	0.6	-0.2	0.3	-0.1	0.3	0.5
Medication: Cholesterol lowering	0.1	0.2	0.6	-0.2	-0.6	0.6	-0.1	-0.6	-0.3	-0.2	0.1	-0.3	0.1	-0.3	-0.3	0.1	-0.3	-0.7	0.4	-0.5	-0.2	-0.6
Medication: Lansoprazole	0.1	0.1	0.6	-0.6	-0.1	0.5	-0.5	0.2	0.1	-0.1	-0.2	-0.8	0.2	0.3	-0.0	0.3	-0.0	0.4	-0.1	-0.7	-0.0	-0.2
Leg fat percentage (right)	0.1	0.4	3.3	0.7	0.3	1.8	-0.4	0.5	-0.8	0.2	0.3	-0.5	0.2	0.1	0.5	0.2	0.4	-0.0	0.8	-0.1	1.2	0.4
Whole body fat mass	0.1	0.5	3.7	0.8	-0.3	0.9	-0.7	-0.7	-0.5	0.1	0.1	-1.9	-0.2	-0.8	-0.1	-0.2	-0.1	-0.6	-0.0	-0.8	0.8	-0.1
Leg fat mass (right)	0.1	0.6	4.4	0.8	-0.4	0.8	-0.6	-0.6	-0.6	-0.1	-0.4	-2.1	-0.6	-0.9	-0.3	-0.6	-0.2	-0.5	-0.2	-1.0	0.8	-0.2
Arm fat percentage (left)	0.1	0.6	3.1	0.9	0.4	1.8	-0.6	-0.0	0.1	0.8	1.0	-1.0	0.9	-0.1	0.8	1.0	0.7	-0.0	0.4	0.1	0.7	0.6
Arm fat mass (left)	0.1	0.5	4.1	0.8	-0.5	0.6	-1.1	-1.0	-0.4	-0.2	0.1	-2.0	-0.3	-0.4	-0.3	-0.2	-0.3	-0.8	-0.5	-0.9	0.0	-0.3
Medication: Atorvastatin	0.1	0.2	1.1	-0.6	-0.3	0.1	1.1	0.1	0.1	0.3	-0.6	0.4	-0.4	0.3	-0.4	-0.3	-0.2	0.0	0.1	0.1	0.1	-0.3
Leg fat percentage (left)	0.1	0.3	2.1	0.7	0.1	1.5	-0.5	0.2	-0.7	0.4	0.4	-0.7	0.1	0.3	0.4	0.1	0.3	-0.3	0.7	-0.2	1.0	0.3
Pain experienced in last month	0.1	0.2	0.9	-0.3	-0.2	0.7	-0.4	0.2	-0.6	-0.5	-0.4	0.8	-0.2	0.5	-0.1	-0.3	-0.2	0.1	0.3	-0.9	-0.2	-0.2
Leg fat mass (left)	0.1	0.6	4.9	0.8	-0.4	0.8	-0.6	-0.6	-0.5	-0.0	-0.3	-2.2	-0.6	-0.8	-0.3	-0.6	-0.2	-0.5	-0.2	-0.9	0.8	-0.2
Blood Platelet Count	0.0	0.3	0.8	0.1	-0.2	0.6	-0.2	-0.7	-0.6	0.1	-0.9	-0.1	-0.4	-0.8	-0.8	0.2	-0.9	-0.2	-0.6	0.2	-0.3	-0.7
Hair Pigment	0.0	1.4	8.8	3.0	0.4	0.9	-1.1	-1.2	1.0	0.7	0.7	0.8	0.3	3.0	0.6	0.3	0.4	-0.7	0.2	-0.9	-0.7	0.5

Hub : Genes

VANGL1

Models

Trait associations