TWAS
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Traits
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Traits
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Cardiovascular Disease
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chr22:19,262,852-20,330,744
Best TWAS P=2.07e-07 · Best GWAS P=2.79e-08 conditioned to 0.0167
19.2M
19.4M
19.6M
19.8M
20M
20.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
AC006547.14
0.09
0.00
lasso
4
0.00
6.9e-01
5.4
-5.2
2.1e-07
-0.78
0.02
0.59
TRUE
1
GTEx
Artery Aorta
ARVCF
0.30
0.22
lasso
3
0.23
6.0e-13
5.5
-5.2
2.1e-07
-0.96
0.01
0.99
FALSE
3
GTEx
Nerve Tibial
ARVCF
0.19
0.09
lasso
6
0.13
2.3e-09
5.4
5.2
2.2e-07
0.91
0.01
0.99
FALSE