[Hub]/) : Traits : Cardiovascular Disease : ← →

chr21:44,392,270-45,879,403

Best TWAS P=1.68e-07 · Best GWAS P=4.6e-10 conditioned to 1.2e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	PDXK	0.14	0.11	lasso	3	0.12	6.2e-07	-5.2	-5.2	1.7e-07	-0.11	0.07	0.93	TRUE
4	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HSF2BP	0.16	-0.01	blup	62	0.02	4.7e-02	1.3	5.2	1.9e-07	0.13	0.01	0.20	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RRP1B	0.11	0.09	lasso	11	0.11	3.7e-13	-4.6	-5.2	2.1e-07	-0.13	0.23	0.77	FALSE
3	GTEx	Vagina	PDXK	0.23	0.19	lasso	1	0.23	5.2e-06	-5.2	-5.2	2.1e-07	-0.13	0.09	0.86	FALSE