Best TWAS P=1.68e-07 · Best GWAS P=4.6e-10 conditioned to 1.2e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RRP1B | 0.11 | 0.09 | lasso | 11 | 0.11 | 3.7e-13 | -4.6 | -5.2 | 2.1e-07 | -0.13 | 0.23 | 0.77 | FALSE |
| 2 | GTEx | Artery Aorta | PDXK | 0.14 | 0.11 | lasso | 3 | 0.12 | 6.2e-07 | -5.2 | -5.2 | 1.7e-07 | -0.11 | 0.07 | 0.93 | TRUE |
| 3 | GTEx | Vagina | PDXK | 0.23 | 0.19 | lasso | 1 | 0.23 | 5.2e-06 | -5.2 | -5.2 | 2.1e-07 | -0.13 | 0.09 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HSF2BP | 0.16 | -0.01 | blup | 62 | 0.02 | 4.7e-02 | 1.3 | 5.2 | 1.9e-07 | 0.13 | 0.01 | 0.20 | FALSE |