TWAS
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Traits
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Cardiovascular Disease
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chr6:14,551,209-16,209,635
Best TWAS P=7.16e-10 · Best GWAS P=5.87e-08 conditioned to 0.892
14.6M
14.8M
15M
15.2M
15.4M
15.6M
15.8M
16M
16.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
JARID2
0.14
0.11
lasso
7
0.13
1.5e-16
5.4
-6.2
7.2e-10
-0.89
0
1
TRUE